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FTLD_203701897_02790_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177846
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no clear atrophic alterations are visible in the parietal lobe - no evident atrophy or tissue thinning seen in the limbic cortex - the insular cortex shows no notable changes suggestive of atrophy - no appreciable degenerative or atrophic changes observed in the temporal lobe - occipital lobe appears within normal limits without apparent atrophy - no clear atrophic alterations are visible in the frontal lobe For the ventricles: - inf. lateral ventricle appears within normal size limits with no apparent enlargement - the external csf shows no notable changes suggestive of enlargement - 3rd ventricle maintains its expected proportions without signs of enlargement - mild enlargement of the 4th ventricle - no findings suggestive of enlargement are seen in the lateral ventricle For the subcortical structures: - mild-to-moderate atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens - no appreciable degenerative or atrophic changes observed in the ventral dc - mild atrophy of the left pallidum; normal-to-mild atrophy of the right pallidum - no appreciable degenerative or atrophic changes observed in the putamen - no findings suggestive of atrophy are seen in the caudate - no clear atrophic alterations are visible in the thalamus - basal forebrain appears preserved, with no observable tissue loss - amygdala appears preserved, with no observable tissue loss - hippocampus appears within normal limits without apparent atrophy
BV
FTLD_203167453_02356_MR_Sagittal_MPR_br_raw_20230206184743165_1.d_I10182645
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild-to-moderate atrophy of the left hippocampus - mild atrophy of the right hippocampus - no observable atrophic changes in the putamen - mild bilateral atrophy of the pallidum - no observable atrophic changes in the amygdala - no appreciable degenerative or atrophic changes observed in the thalamus - no evident atrophy or tissue thinning seen in the basal forebrain - mild-to-moderate bilateral atrophy of the caudate - ventral dc demonstrates a healthy morphology without signs of atrophy - no observable atrophic changes in the accumbens For the ventricles: - mild enlargement of the 4th ventricle - external csf maintains its expected proportions without signs of enlargement - mild bilateral enlargement of the lateral ventricle - the inf. lateral ventricle shows no notable changes suggestive of enlargement - 3rd ventricle maintains a typical volume without observable enlargement For the cerebral cortex: - the frontal lobe shows no notable changes suggestive of atrophy - the limbic cortex shows no notable changes suggestive of atrophy - parietal lobe demonstrates a healthy morphology without signs of atrophy - the temporal lobe shows no notable changes suggestive of atrophy - no appreciable degenerative or atrophic changes observed in the occipital lobe - no appreciable degenerative or atrophic changes observed in the insular cortex
BV
FTLD_203365973_03376_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450629
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild-to-moderate atrophy of the left thalamus; normal-to-mild atrophy of the right thalamus - severe bilateral atrophy of the amygdala - no observable atrophic changes in the ventral dc - severe atrophy of the left hippocampus - mild-to-moderate atrophy of the right hippocampus - moderate atrophy of the left accumbens and mild atrophy of the right accumbens - mild-to-moderate bilateral atrophy of the pallidum - mild-to-moderate bilateral atrophy of the caudate - moderate-to-severe atrophy of the left putamen and mild-to-moderate atrophy of the right putamen - no observable atrophic changes in the basal forebrain For the ventricles: - 4th ventricle maintains its expected proportions without signs of enlargement - mild-to-moderate enlargement of the external csf - 3rd ventricle appears to be of normal dimensions, with no observable increase in size - severe bilateral enlargement of the inf. lateral ventricle - mild-to-moderate enlargement of the left lateral ventricle and mild enlargement of the right lateral ventricle For the cerebral cortex: - severe atrophy of the left temporal lobe and moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), fusiform gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), inf. temporal gyrus (moderate-to-severe atrophy on the left and normal-to-mild atrophy on the right), middle temporal gyrus (moderate atrophy on the left and mild atrophy on the right), sup. temporal gyrus (mild-to-moderate atrophy on the left and normal on the right) and planum polare (mild atrophy on the left and normal on the right) - no observable atrophic changes in the parietal lobe - moderate bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: posterior insula (moderate-to-severe atrophy on the left and moderate atrophy on the right), anterior insula (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), central operculum (moderate atrophy on the left and normal on the right), frontal operculum (mild atrophy on the right) and parietal operculum (normal on the left and mild atrophy on the right) - mild-to-moderate atrophy of the left limbic cortex and mild atrophy of the right limbic cortex; focal volume loss observed in the following subregions: entorhinal area (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), anterior cingulate gyrus (mild atrophy both left/right) and parahippocampal gyrus (mild atrophy on the left and normal on the right) - occipital lobe maintains a normal appearance with no observable atrophic features - no observable atrophic changes in the frontal lobe
SV
FTLD_203285992_03298_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10177415
On a T1-weighted brain MRI we observed: For the ventricles: - mild enlargement of the external csf - mild enlargement of the 3rd ventricle - severe enlargement of the left inf. lateral ventricle and moderate-to-severe enlargement of the right inf. lateral ventricle - no evident size increase noted in the 4th ventricle - moderate-to-severe enlargement of the left lateral ventricle and mild-to-moderate enlargement of the right lateral ventricle For the cerebral cortex: - severe atrophy of the left frontal lobe; normal-to-mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: sup. frontal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), opercular inf. frontal gyrus (mild atrophy both left/right), medial frontal cortex (mild atrophy both left/right), lateral orbital gyrus (mild atrophy both left/right), supplementary motor cortex (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), gyrus rectus (mild-to-moderate atrophy on the left and normal on the right), medial orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), subcallosal area (mild atrophy on the left and normal-to-mild atrophy on the right), posterior orbital gyrus (mild atrophy on the left and normal on the right), precentral gyrus (mild atrophy on the left), sup. frontal gyrus medial segment (mild atrophy on the left), triangular inf. frontal gyrus (mild atrophy on the left) and middle frontal gyrus (mild atrophy on the left) - no clear atrophic alterations are visible in the parietal lobe - severe atrophy of the left temporal lobe; normal-to-mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), middle temporal gyrus (moderate atrophy on the left and normal on the right), fusiform gyrus (moderate atrophy on the left and normal on the right), inf. temporal gyrus (mild-to-moderate atrophy on the left) and planum temporale (mild atrophy on the left) - moderate atrophy of the left limbic cortex and mild-to-moderate atrophy of the right limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), entorhinal area (mild-to-moderate atrophy on the left and mild atrophy on the right), middle cingulate gyrus (mild atrophy on the left and normal on the right) and parahippocampal gyrus (mild atrophy on the left and normal on the right) - moderate atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (severe atrophy on the left and mild-to-moderate atrophy on the right), central operculum (mild atrophy on the left and normal-to-mild atrophy on the right) and posterior insula (mild atrophy on the left) - the occipital lobe shows no notable changes suggestive of atrophy For the subcortical structures: - severe atrophy of the left accumbens and moderate atrophy of the right accumbens - severe atrophy of the left caudate and mild atrophy of the right caudate - mild-to-moderate atrophy of the left hippocampus - the left hippocampus volume is borderline low - basal forebrain appears preserved, with no observable tissue loss - moderate atrophy of the left pallidum; the right pallidum is normal - mild atrophy of the left thalamus; the right thalamus is normal - the ventral dc shows no notable changes suggestive of atrophy - severe atrophy of the left amygdala and moderate-to-severe atrophy of the right amygdala - severe atrophy of the left putamen and mild atrophy of the right putamen
SV
FTLD_203196400_02009_MR_Sagittal_MP-Rage_br_raw_20230209094406847_I10183255
On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy both left/right) and parahippocampal gyrus (mild atrophy on the left and normal on the right) - mild atrophy of the left frontal lobe and mild-to-moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: posterior orbital gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), opercular inf. frontal gyrus (mild atrophy both left/right), orbital inf. frontal gyrus (mild atrophy both left/right), middle frontal gyrus (mild atrophy both left/right), gyrus rectus (mild atrophy on the left and normal-to-mild atrophy on the right), triangular inf. frontal gyrus (normal on the left and mild atrophy on the right), precentral gyrus (mild atrophy on the left and normal on the right), precentral gyrus medial segment (mild atrophy on the left and normal on the right) and sup. frontal gyrus medial segment (normal on the left and mild atrophy on the right) - parietal lobe appears preserved, with no observable tissue loss - occipital lobe appears within normal limits without apparent atrophy - mild bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: transverse temporal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), temporal pole (normal-to-mild atrophy on the left and mild atrophy on the right), fusiform gyrus (mild atrophy on the left and normal on the right) and planum temporale (normal on the left and mild atrophy on the right) - mild-to-moderate atrophy of the left insular cortex and moderate atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (mild-to-moderate atrophy both left/right), central operculum (mild-to-moderate atrophy both left/right) and posterior insula (normal on the left and mild-to-moderate atrophy on the right) For the subcortical structures: - severe bilateral atrophy of the caudate - moderate-to-severe atrophy of the left putamen and moderate atrophy of the right putamen - mild-to-moderate bilateral atrophy of the thalamus - mild bilateral atrophy of the ventral dc - basal forebrain appears preserved, with no observable tissue loss - mild bilateral atrophy of the amygdala - the left hippocampus volume is borderline low - the left hippocampus volume is borderline low - moderate bilateral atrophy of the pallidum - moderate-to-severe bilateral atrophy of the accumbens For the ventricles: - severe enlargement of the 4th ventricle - severe bilateral enlargement of the lateral ventricle - severe bilateral enlargement of the inf. lateral ventricle - moderate-to-severe enlargement of the 3rd ventricle - moderate enlargement of the external csf
BV
ADNI_072_S_4391_MR_MPRAGE_br_raw_20120110102851585_134_S135851_I276963
On a T1-weighted brain MRI we observed: For the subcortical structures: - pallidum maintains a normal appearance with no observable atrophic features - no evident atrophy or tissue thinning seen in the accumbens - putamen appears within normal limits without apparent atrophy - no appreciable degenerative or atrophic changes observed in the ventral dc - mild atrophy of the left basal forebrain; normal-to-mild atrophy of the right basal forebrain - mild atrophy of the right amygdala; the left amygdala is normal - caudate maintains a normal appearance with no observable atrophic features - thalamus demonstrates a healthy morphology without signs of atrophy - no clear atrophic alterations are visible in the hippocampus For the cerebral cortex: - occipital lobe appears preserved, with no observable tissue loss - no appreciable degenerative or atrophic changes observed in the frontal lobe - no clear atrophic alterations are visible in the insular cortex - no observable atrophic changes in the temporal lobe - the parietal lobe shows no notable changes suggestive of atrophy - mild atrophy of the right limbic cortex; normal-to-mild atrophy of the left limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (normal on the left and mild atrophy on the right) and middle cingulate gyrus (normal on the left and mild atrophy on the right) For the ventricles: - 4th ventricle maintains a typical volume without observable enlargement - no findings suggestive of enlargement are seen in the external csf - no findings suggestive of enlargement are seen in the inf. lateral ventricle - lateral ventricle appears within normal size limits with no apparent enlargement - no clear enlargement or abnormal growth seen in the 3rd ventricle
CN
ADNI_037_S_4001_MR_MT1__GradWarp__N3m_Br_20120412210525847_S100198_I297310
On a T1-weighted brain MRI we observed: For the ventricles: - the lateral ventricle shows no notable changes suggestive of enlargement - the external csf shows no notable changes suggestive of enlargement - 3rd ventricle maintains its expected proportions without signs of enlargement - no appreciable enlargement noted in the 4th ventricle - mild enlargement of the right inf. lateral ventricle; the left inf. lateral ventricle is normal For the subcortical structures: - accumbens maintains a normal appearance with no observable atrophic features - the left hippocampus volume is borderline low - the thalamus shows no notable changes suggestive of atrophy - no clear atrophic alterations are visible in the putamen - no observable atrophic changes in the pallidum - no appreciable degenerative or atrophic changes observed in the amygdala - ventral dc demonstrates a healthy morphology without signs of atrophy - basal forebrain appears preserved, with no observable tissue loss - no observable atrophic changes in the caudate For the cerebral cortex: - mild-to-moderate atrophy of the left parietal lobe and mild atrophy of the right parietal lobe; focal volume loss observed in the following subregions: precuneus (mild-to-moderate atrophy on the left and mild atrophy on the right), angular gyrus (mild atrophy both left/right), supramarginal gyrus (mild atrophy on the left and normal on the right) and sup. parietal lobule (normal on the left and mild atrophy on the right) - limbic cortex demonstrates a healthy morphology without signs of atrophy - no findings suggestive of atrophy are seen in the temporal lobe - the frontal lobe shows no notable changes suggestive of atrophy - insular cortex demonstrates a healthy morphology without signs of atrophy - occipital lobe appears within normal limits without apparent atrophy
AD
FTLD_203686328_03828_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10451178
On a T1-weighted brain MRI we observed: For the cerebral cortex: - parietal lobe maintains a normal appearance with no observable atrophic features - insular cortex maintains a normal appearance with no observable atrophic features - no evident atrophy or tissue thinning seen in the limbic cortex - frontal lobe appears preserved, with no observable tissue loss - no clear atrophic alterations are visible in the temporal lobe - no observable atrophic changes in the occipital lobe For the ventricles: - external csf maintains a typical volume without observable enlargement - mild bilateral enlargement of the inf. lateral ventricle - no evident size increase noted in the lateral ventricle - no findings suggestive of enlargement are seen in the 3rd ventricle - 4th ventricle maintains a typical volume without observable enlargement For the subcortical structures: - amygdala appears preserved, with no observable tissue loss - mild bilateral atrophy of the pallidum - the left hippocampus volume is borderline low - the left hippocampus volume is borderline low - basal forebrain appears preserved, with no observable tissue loss - no evident atrophy or tissue thinning seen in the putamen - thalamus maintains a normal appearance with no observable atrophic features - ventral dc appears within normal limits without apparent atrophy - no observable atrophic changes in the caudate - mild atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens
BV
FTLD_203107266_02660_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177776
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no findings suggestive of atrophy are seen in the occipital lobe - moderate-to-severe atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (moderate-to-severe atrophy on the left and mild atrophy on the right), anterior cingulate gyrus (moderate atrophy on the left and normal-to-mild atrophy on the right) and parahippocampal gyrus (moderate atrophy on the left and normal on the right) - parietal lobe demonstrates a healthy morphology without signs of atrophy - severe atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: posterior insula (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), anterior insula (severe atrophy on the left and normal on the right), central operculum (mild atrophy on the left and normal-to-mild atrophy on the right), frontal operculum (mild-to-moderate atrophy on the left) and parietal operculum (mild atrophy on the left) - severe atrophy of the left temporal lobe and moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (severe atrophy on the left and moderate atrophy on the right), sup. temporal gyrus (moderate-to-severe atrophy on the left and mild atrophy on the right), inf. temporal gyrus (mild-to-moderate atrophy both left/right), planum polare (moderate-to-severe atrophy on the left and normal on the right), fusiform gyrus (mild atrophy both left/right), middle temporal gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), planum temporale (mild-to-moderate atrophy on the left and normal on the right) and transverse temporal gyrus (mild atrophy on the left and normal on the right) - frontal lobe maintains a normal appearance with no observable atrophic features For the ventricles: - mild-to-moderate enlargement of the 3rd ventricle - mild enlargement of the left lateral ventricle; normal-to-mild enlargement of the right lateral ventricle - mild-to-moderate enlargement of the external csf - severe enlargement of the left inf. lateral ventricle and moderate enlargement of the right inf. lateral ventricle - no clear enlargement or abnormal growth seen in the 4th ventricle For the subcortical structures: - severe atrophy of the left amygdala and moderate-to-severe atrophy of the right amygdala - no appreciable degenerative or atrophic changes observed in the caudate - moderate atrophy of the left putamen; the right putamen is normal - mild-to-moderate atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens - ventral dc maintains a normal appearance with no observable atrophic features - thalamus maintains a normal appearance with no observable atrophic features - the basal forebrain shows no notable changes suggestive of atrophy - moderate atrophy of the left hippocampus - no evident atrophy or tissue thinning seen in the pallidum
SV
FTLD_203833438_01833_MR_Sagittal_MP-Rage_br_raw_20230206151827200_I10181363
On a T1-weighted brain MRI we observed: For the subcortical structures: - severe bilateral atrophy of the caudate - severe atrophy of the left putamen and moderate-to-severe atrophy of the right putamen - no appreciable degenerative or atrophic changes observed in the basal forebrain - the ventral dc shows no notable changes suggestive of atrophy - mild-to-moderate atrophy of the left hippocampus - mild atrophy of the right hippocampus - moderate atrophy of the left pallidum and mild atrophy of the right pallidum - moderate-to-severe atrophy of the left amygdala and mild-to-moderate atrophy of the right amygdala - mild-to-moderate atrophy of the left thalamus and mild atrophy of the right thalamus - severe atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens For the ventricles: - mild enlargement of the 4th ventricle - severe bilateral enlargement of the lateral ventricle - severe enlargement of the left inf. lateral ventricle and moderate enlargement of the right inf. lateral ventricle - moderate enlargement of the 3rd ventricle - moderate enlargement of the external csf For the cerebral cortex: - parietal lobe demonstrates a healthy morphology without signs of atrophy - moderate atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: temporal pole (mild-to-moderate atrophy on the left and mild atrophy on the right), planum temporale (mild atrophy on the left), sup. temporal gyrus (mild atrophy on the left), inf. temporal gyrus (mild-to-moderate atrophy on the left and normal on the right) and middle temporal gyrus (mild atrophy on the left) - severe atrophy of the left frontal lobe and moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (moderate-to-severe atrophy on the left and moderate atrophy on the right), supplementary motor cortex (mild-to-moderate atrophy both left/right), precentral gyrus (mild-to-moderate atrophy both left/right), triangular inf. frontal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), posterior orbital gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), sup. frontal gyrus (moderate atrophy on the left and normal-to-mild atrophy on the right), gyrus rectus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), orbital inf. frontal gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), opercular inf. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), frontal pole (mild atrophy on the left) and medial frontal cortex (mild atrophy on the left) - mild-to-moderate atrophy of the left limbic cortex and mild atrophy of the right limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild-to-moderate atrophy both left/right) and parahippocampal gyrus (moderate atrophy on the left and normal-to-mild atrophy on the right) - occipital lobe appears within normal limits without apparent atrophy - moderate-to-severe atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (severe atrophy on the left and mild atrophy on the right), central operculum (mild-to-moderate atrophy on the left and mild atrophy on the right), posterior insula (normal-to-mild atrophy on the left and mild atrophy on the right) and frontal operculum (mild-to-moderate atrophy on the left and normal on the right)
PNFA
FTLD_203197205_03509_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450866
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild atrophy of the left pallidum; the right pallidum is normal - mild atrophy of the left basal forebrain; the right basal forebrain is normal - ventral dc maintains a normal appearance with no observable atrophic features - mild atrophy of the left accumbens; the right accumbens is normal - severe atrophy of the left amygdala and moderate-to-severe atrophy of the right amygdala - caudate maintains a normal appearance with no observable atrophic features - moderate atrophy of the left hippocampus - mild atrophy of the right hippocampus - no observable atrophic changes in the thalamus - mild-to-moderate atrophy of the left putamen and mild atrophy of the right putamen For the cerebral cortex: - parietal lobe appears within normal limits without apparent atrophy - mild-to-moderate atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: parahippocampal gyrus (moderate atrophy on the left and normal on the right), entorhinal area (mild-to-moderate atrophy on the left and normal on the right), middle cingulate gyrus (mild atrophy on the left) and posterior cingulate gyrus (mild atrophy on the left and normal on the right) - occipital lobe demonstrates a healthy morphology without signs of atrophy - severe atrophy of the left temporal lobe and moderate-to-severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (mild-to-moderate atrophy both left/right), inf. temporal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), middle temporal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), fusiform gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), planum polare (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) and sup. temporal gyrus (mild atrophy on the left) - the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in medial frontal cortex (moderate atrophy on the left), gyrus rectus (mild atrophy on the left and normal-to-mild atrophy on the right), precentral gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and sup. frontal gyrus medial segment (normal on the left and mild atrophy on the right) - moderate atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and mild atrophy on the right), posterior insula (mild-to-moderate atrophy on the left and mild atrophy on the right) and parietal operculum (normal-to-mild atrophy on the left and mild atrophy on the right) For the ventricles: - 4th ventricle appears within normal size limits with no apparent enlargement - no appreciable enlargement noted in the 3rd ventricle - external csf maintains a typical volume without observable enlargement - mild-to-moderate enlargement of the left lateral ventricle and mild enlargement of the right lateral ventricle - moderate-to-severe enlargement of the left inf. lateral ventricle; normal-to-mild enlargement of the right inf. lateral ventricle
SV
FTLD_203213070_03071_MR_Accelerated_Sagittal_IR-FSPGR_br_raw_202_I10450227
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild bilateral atrophy of the caudate - mild-to-moderate atrophy of the left accumbens and mild atrophy of the right accumbens - mild bilateral atrophy of the thalamus - moderate atrophy of the left putamen and mild-to-moderate atrophy of the right putamen - mild bilateral atrophy of the pallidum - mild atrophy of the left hippocampus - mild atrophy of the right hippocampus - no appreciable degenerative or atrophic changes observed in the basal forebrain - the ventral dc shows no notable changes suggestive of atrophy - the amygdala shows no notable changes suggestive of atrophy For the ventricles: - moderate-to-severe bilateral enlargement of the lateral ventricle - no findings suggestive of enlargement are seen in the 4th ventricle - moderate-to-severe enlargement of the 3rd ventricle - mild bilateral enlargement of the inf. lateral ventricle - mild enlargement of the external csf For the cerebral cortex: - no clear atrophic alterations are visible in the limbic cortex - no evident atrophy or tissue thinning seen in the frontal lobe - no observable atrophic changes in the temporal lobe - occipital lobe appears preserved, with no observable tissue loss - mild-to-moderate bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: central operculum (mild atrophy on the left and moderate atrophy on the right), posterior insula (mild atrophy both left/right), parietal operculum (mild atrophy on the left and normal-to-mild atrophy on the right), frontal operculum (mild atrophy on the left and normal on the right) and anterior insula (normal on the left and mild atrophy on the right) - parietal lobe maintains a normal appearance with no observable atrophic features
BV
FTLD_203520125_02522_MR_Sagittal_MP-Rage_br_raw_20230206161149625_I10181563
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild-to-moderate atrophy of the left putamen and mild atrophy of the right putamen - no clear atrophic alterations are visible in the basal forebrain - mild bilateral atrophy of the accumbens - mild atrophy of the left thalamus; normal-to-mild atrophy of the right thalamus - caudate demonstrates a healthy morphology without signs of atrophy - pallidum demonstrates a healthy morphology without signs of atrophy - the left hippocampus volume is borderline low - mild atrophy of the left ventral dc; the right ventral dc is normal - no clear atrophic alterations are visible in the amygdala For the cerebral cortex: - no findings suggestive of atrophy are seen in the occipital lobe - mild atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (mild atrophy both left/right) and central operculum (mild atrophy both left/right) - mild atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: inf. temporal gyrus (mild atrophy both left/right) - mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the left) - mild-to-moderate atrophy of the left frontal lobe and mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: precentral gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), sup. frontal gyrus medial segment (mild-to-moderate atrophy on the right), lateral orbital gyrus (mild atrophy on the left), medial frontal cortex (mild atrophy on the left and normal on the right), sup. frontal gyrus (mild atrophy on the left and normal on the right), supplementary motor cortex (normal on the left and mild atrophy on the right), middle frontal gyrus (mild atrophy on the left and normal on the right), anterior orbital gyrus (mild atrophy on the left and normal on the right) and posterior orbital gyrus (mild atrophy on the right) - no appreciable degenerative or atrophic changes observed in the parietal lobe For the ventricles: - the 3rd ventricle shows no notable changes suggestive of enlargement - moderate enlargement of the left lateral ventricle and moderate-to-severe enlargement of the right lateral ventricle - mild-to-moderate enlargement of the left inf. lateral ventricle; normal-to-mild enlargement of the right inf. lateral ventricle - mild enlargement of the external csf - mild enlargement of the 4th ventricle
PNFA
FTLD_203885673_02378_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177207
On a T1-weighted brain MRI we observed: For the subcortical structures: - no clear atrophic alterations are visible in the basal forebrain - caudate demonstrates a healthy morphology without signs of atrophy - no clear atrophic alterations are visible in the thalamus - no findings suggestive of atrophy are seen in the ventral dc - moderate atrophy of the left hippocampus - the left hippocampus volume is borderline low - mild-to-moderate atrophy of the left accumbens and mild atrophy of the right accumbens - severe atrophy of the left amygdala and moderate atrophy of the right amygdala - mild atrophy of the left pallidum; normal-to-mild atrophy of the right pallidum - mild-to-moderate atrophy of the left putamen; the right putamen is normal For the cerebral cortex: - mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and mild atrophy on the right) and posterior insula (mild atrophy on the left and normal-to-mild atrophy on the right) - severe atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy on the left and moderate atrophy on the right), planum polare (mild atrophy both left/right), middle temporal gyrus (mild-to-moderate atrophy on the left and normal on the right), fusiform gyrus (mild-to-moderate atrophy on the left) and inf. temporal gyrus (mild atrophy on the left and normal on the right) - no appreciable degenerative or atrophic changes observed in the parietal lobe - mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (moderate atrophy on the left and mild atrophy on the right) and parahippocampal gyrus (mild atrophy both left/right) - no observable atrophic changes in the frontal lobe - no findings suggestive of atrophy are seen in the occipital lobe For the ventricles: - no findings suggestive of enlargement are seen in the 3rd ventricle - severe enlargement of the left inf. lateral ventricle and mild-to-moderate enlargement of the right inf. lateral ventricle - 4th ventricle maintains a typical volume without observable enlargement - mild-to-moderate enlargement of the left lateral ventricle; the right lateral ventricle is normal - external csf maintains its expected proportions without signs of enlargement
SV
FTLD_203196400_02009_MR_Sagittal_MP-Rage_br_raw_20230209094406847_I10183255
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild bilateral atrophy of the ventral dc - moderate-to-severe bilateral atrophy of the accumbens - moderate bilateral atrophy of the pallidum - severe bilateral atrophy of the caudate - mild-to-moderate bilateral atrophy of the thalamus - moderate-to-severe atrophy of the left putamen and moderate atrophy of the right putamen - no findings suggestive of atrophy are seen in the basal forebrain - mild bilateral atrophy of the amygdala - the left hippocampus volume is borderline low - the left hippocampus volume is borderline low For the ventricles: - severe bilateral enlargement of the lateral ventricle - severe enlargement of the 4th ventricle - moderate-to-severe enlargement of the 3rd ventricle - severe bilateral enlargement of the inf. lateral ventricle - moderate enlargement of the external csf For the cerebral cortex: - mild bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: transverse temporal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), temporal pole (normal-to-mild atrophy on the left and mild atrophy on the right), fusiform gyrus (mild atrophy on the left and normal on the right) and planum temporale (normal on the left and mild atrophy on the right) - mild atrophy of the left frontal lobe and mild-to-moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: posterior orbital gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), opercular inf. frontal gyrus (mild atrophy both left/right), orbital inf. frontal gyrus (mild atrophy both left/right), middle frontal gyrus (mild atrophy both left/right), gyrus rectus (mild atrophy on the left and normal-to-mild atrophy on the right), triangular inf. frontal gyrus (normal on the left and mild atrophy on the right), precentral gyrus (mild atrophy on the left and normal on the right), precentral gyrus medial segment (mild atrophy on the left and normal on the right) and sup. frontal gyrus medial segment (normal on the left and mild atrophy on the right) - mild-to-moderate atrophy of the left insular cortex and moderate atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (mild-to-moderate atrophy both left/right), central operculum (mild-to-moderate atrophy both left/right) and posterior insula (normal on the left and mild-to-moderate atrophy on the right) - mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy both left/right) and parahippocampal gyrus (mild atrophy on the left and normal on the right) - parietal lobe maintains a normal appearance with no observable atrophic features - no findings suggestive of atrophy are seen in the occipital lobe
BV
ADNI_041_S_4427_MR_MPRAGE_br_raw_20111219161558046_114_S133927_I273198
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no appreciable degenerative or atrophic changes observed in the temporal lobe - mild atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: posterior cingulate gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and middle cingulate gyrus (mild atrophy on the right) - insular cortex appears preserved, with no observable tissue loss - occipital lobe appears within normal limits without apparent atrophy - frontal lobe appears preserved, with no observable tissue loss - no appreciable degenerative or atrophic changes observed in the parietal lobe For the ventricles: - no evident size increase noted in the 3rd ventricle - mild bilateral enlargement of the lateral ventricle - no findings suggestive of enlargement are seen in the 4th ventricle - external csf appears to be of normal dimensions, with no observable increase in size - no appreciable enlargement noted in the inf. lateral ventricle For the subcortical structures: - no appreciable degenerative or atrophic changes observed in the thalamus - no clear atrophic alterations are visible in the amygdala - no clear atrophic alterations are visible in the basal forebrain - caudate demonstrates a healthy morphology without signs of atrophy - pallidum maintains a normal appearance with no observable atrophic features - accumbens appears within normal limits without apparent atrophy - no clear atrophic alterations are visible in the putamen - mild atrophy of the left hippocampus - ventral dc appears preserved, with no observable tissue loss
CN
FTLD_203679862_03267_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450433
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no findings suggestive of atrophy are seen in the frontal lobe - parietal lobe maintains a normal appearance with no observable atrophic features - no clear atrophic alterations are visible in the insular cortex - occipital lobe maintains a normal appearance with no observable atrophic features - the temporal lobe shows no notable changes suggestive of atrophy - mild atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (normal on the left and mild atrophy on the right), parahippocampal gyrus (normal on the left and mild atrophy on the right) and anterior cingulate gyrus (normal on the left and mild atrophy on the right) For the subcortical structures: - caudate appears within normal limits without apparent atrophy - the basal forebrain shows no notable changes suggestive of atrophy - mild atrophy of the left ventral dc and mild-to-moderate atrophy of the right ventral dc - no observable atrophic changes in the accumbens - mild atrophy of the right hippocampus - mild-to-moderate bilateral atrophy of the thalamus - mild-to-moderate atrophy of the right amygdala; the left amygdala is normal - mild bilateral atrophy of the putamen - mild bilateral atrophy of the pallidum For the ventricles: - no evident size increase noted in the 3rd ventricle - 4th ventricle maintains its expected proportions without signs of enlargement - inf. lateral ventricle appears within normal size limits with no apparent enlargement - mild bilateral enlargement of the lateral ventricle - mild enlargement of the external csf
PNFA
ADNI_057_S_0941_MR_MPR__GradWarp__B1_Correction__N3__Scaled_Br_20071115130532568_S42111_I82342
On a T1-weighted brain MRI we observed: For the subcortical structures: - no clear atrophic alterations are visible in the thalamus - no observable atrophic changes in the pallidum - mild atrophy of the left hippocampus - mild-to-moderate atrophy of the right hippocampus - no findings suggestive of atrophy are seen in the ventral dc - accumbens appears preserved, with no observable tissue loss - moderate atrophy of the left amygdala and mild-to-moderate atrophy of the right amygdala - no clear atrophic alterations are visible in the basal forebrain - mild atrophy of the left putamen; the right putamen is normal - mild atrophy of the left caudate; normal-to-mild atrophy of the right caudate For the ventricles: - severe enlargement of the left inf. lateral ventricle and mild-to-moderate enlargement of the right inf. lateral ventricle - mild enlargement of the 4th ventricle - 3rd ventricle appears within normal size limits with no apparent enlargement - mild-to-moderate bilateral enlargement of the lateral ventricle - mild-to-moderate enlargement of the external csf For the cerebral cortex: - mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the left) and entorhinal area (mild atrophy on the left and normal on the right) - moderate-to-severe atrophy of the left parietal lobe and mild atrophy of the right parietal lobe; focal volume loss observed in the following subregions: angular gyrus (mild atrophy both left/right), supramarginal gyrus (mild-to-moderate atrophy on the left and normal on the right), postcentral gyrus (normal on the left and mild atrophy on the right), precuneus (mild atrophy on the left and normal on the right) and sup. parietal lobule (mild atrophy on the left) - mild bilateral atrophy of the occipital lobe; focal volume loss observed in the following subregions: calcarine cortex (mild atrophy on the left and normal-to-mild atrophy on the right) and sup. occipital gyrus (normal on the left and mild atrophy on the right) - mild bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: parietal operculum (normal on the left and mild atrophy on the right), anterior insula (mild atrophy on the left and normal on the right) and posterior insula (mild atrophy on the left and normal on the right) - the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in precentral gyrus medial segment (moderate atrophy on the left and normal on the right), middle frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and orbital inf. frontal gyrus (mild atrophy on the right) - moderate atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), inf. temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), middle temporal gyrus (mild-to-moderate atrophy on the left and normal on the right) and temporal pole (mild atrophy on the left and normal on the right)
AD
FTLD_203011672_03271_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177308
On a T1-weighted brain MRI we observed: For the cerebral cortex: - severe atrophy of the left temporal lobe and moderate-to-severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (severe atrophy on the left and moderate-to-severe atrophy on the right), inf. temporal gyrus (mild-to-moderate atrophy on the left and moderate atrophy on the right), middle temporal gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), planum polare (mild atrophy both left/right), sup. temporal gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) and fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) - no appreciable degenerative or atrophic changes observed in the parietal lobe - occipital lobe demonstrates a healthy morphology without signs of atrophy - moderate atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), posterior insula (mild-to-moderate atrophy on the left and mild atrophy on the right) and central operculum (mild atrophy on the left and normal on the right) - mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (moderate atrophy on the left and mild-to-moderate atrophy on the right) and parahippocampal gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right) - mild atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: triangular inf. frontal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), gyrus rectus (mild atrophy both left/right), supplementary motor cortex (normal-to-mild atrophy on the left and mild atrophy on the right), medial orbital gyrus (mild atrophy on the left and normal on the right) and posterior orbital gyrus (normal on the left and mild atrophy on the right) For the subcortical structures: - moderate-to-severe atrophy of the left accumbens and mild atrophy of the right accumbens - severe atrophy of the left putamen and moderate atrophy of the right putamen - severe bilateral atrophy of the amygdala - mild-to-moderate atrophy of the left pallidum; normal-to-mild atrophy of the right pallidum - no appreciable degenerative or atrophic changes observed in the thalamus - no observable atrophic changes in the basal forebrain - moderate-to-severe atrophy of the left hippocampus - moderate atrophy of the right hippocampus - the ventral dc shows no notable changes suggestive of atrophy - mild-to-moderate atrophy of the left caudate and mild atrophy of the right caudate For the ventricles: - mild enlargement of the external csf - severe enlargement of the left inf. lateral ventricle and moderate enlargement of the right inf. lateral ventricle - moderate enlargement of the 3rd ventricle - moderate enlargement of the left lateral ventricle and mild enlargement of the right lateral ventricle - no appreciable enlargement noted in the 4th ventricle
SV
ADNI_053_S_5208_MR_MPRAGE_br_raw_20130618080348968_151_S192574_I376939
On a T1-weighted brain MRI we observed: For the subcortical structures: - moderate-to-severe atrophy of the left hippocampus - severe atrophy of the right hippocampus - mild-to-moderate atrophy of the left amygdala and moderate-to-severe atrophy of the right amygdala - mild atrophy of the left putamen and mild-to-moderate atrophy of the right putamen - mild bilateral atrophy of the caudate - mild bilateral atrophy of the accumbens - no appreciable degenerative or atrophic changes observed in the basal forebrain - mild atrophy of the left pallidum and moderate atrophy of the right pallidum - mild bilateral atrophy of the ventral dc - mild atrophy of the left thalamus and moderate atrophy of the right thalamus For the ventricles: - mild-to-moderate enlargement of the external csf - 4th ventricle appears within normal size limits with no apparent enlargement - mild enlargement of the left lateral ventricle; normal-to-mild enlargement of the right lateral ventricle - mild enlargement of the left inf. lateral ventricle and moderate-to-severe enlargement of the right inf. lateral ventricle - mild-to-moderate enlargement of the 3rd ventricle For the cerebral cortex: - mild-to-moderate atrophy of the right limbic cortex; normal-to-mild atrophy of the left limbic cortex; focal volume loss observed in the following subregions: entorhinal area (normal on the left and mild-to-moderate atrophy on the right), middle cingulate gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), anterior cingulate gyrus (normal on the left and mild atrophy on the right) and parahippocampal gyrus (normal on the left and mild atrophy on the right) - the frontal lobe shows no notable changes suggestive of atrophy - mild atrophy of the left occipital lobe; normal-to-mild atrophy of the right occipital lobe; focal volume loss observed in the following subregions: middle occipital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. occipital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), cuneus (mild atrophy on the left and normal on the right) and inf. occipital gyrus (mild atrophy on the left and normal on the right) - mild atrophy of the right parietal lobe; normal-to-mild atrophy of the left parietal lobe; focal volume loss observed in the following subregions: postcentral gyrus medial segment (mild atrophy on the right), sup. parietal lobule (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right) and precuneus (mild atrophy on the left and normal on the right) - no observable atrophic changes in the insular cortex - mild-to-moderate atrophy of the right temporal lobe; the left temporal lobe is normal; focal volume loss observed in the following subregions: middle temporal gyrus (normal on the left and mild-to-moderate atrophy on the right), temporal pole (normal on the left and mild-to-moderate atrophy on the right), fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and inf. temporal gyrus (mild atrophy on the right)
AD
FTLD_203014537_02731_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178217
On a T1-weighted brain MRI we observed: For the ventricles: - mild enlargement of the left lateral ventricle; normal-to-mild enlargement of the right lateral ventricle - inf. lateral ventricle maintains a typical volume without observable enlargement - external csf appears to be of normal dimensions, with no observable increase in size - 4th ventricle maintains its expected proportions without signs of enlargement - no clear enlargement or abnormal growth seen in the 3rd ventricle For the subcortical structures: - the caudate shows no notable changes suggestive of atrophy - hippocampus maintains a normal appearance with no observable atrophic features - basal forebrain appears within normal limits without apparent atrophy - thalamus appears preserved, with no observable tissue loss - moderate atrophy of the left pallidum; the right pallidum is normal - no appreciable degenerative or atrophic changes observed in the amygdala - the accumbens shows no notable changes suggestive of atrophy - mild atrophy of the left ventral dc; the right ventral dc is normal - mild atrophy of the left putamen; the right putamen is normal For the cerebral cortex: - limbic cortex maintains a normal appearance with no observable atrophic features - mild-to-moderate atrophy of the left frontal lobe and mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: precentral gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), middle frontal gyrus (mild atrophy both left/right), posterior orbital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), anterior orbital gyrus (mild atrophy on the left) and sup. frontal gyrus medial segment (normal on the left and mild atrophy on the right) - parietal lobe appears within normal limits without apparent atrophy - mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (mild atrophy both left/right) - temporal lobe appears within normal limits without apparent atrophy - the occipital lobe shows no notable changes suggestive of atrophy
PNFA
FTLD_203932722_03223_MR_Accelerated_Sagittal_MPRAGE_br_raw_20241_I11047338
On a T1-weighted brain MRI we observed: For the ventricles: - mild bilateral enlargement of the inf. lateral ventricle - the 4th ventricle shows no notable changes suggestive of enlargement - mild enlargement of the left lateral ventricle and mild-to-moderate enlargement of the right lateral ventricle - moderate-to-severe enlargement of the external csf - no appreciable enlargement noted in the 3rd ventricle For the cerebral cortex: - occipital lobe demonstrates a healthy morphology without signs of atrophy - mild-to-moderate atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: middle temporal gyrus (mild-to-moderate atrophy both left/right), sup. temporal gyrus (mild atrophy both left/right), planum temporale (mild atrophy on the left and normal-to-mild atrophy on the right) and temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right) - parietal lobe appears within normal limits without apparent atrophy - limbic cortex appears within normal limits without apparent atrophy - no evident atrophy or tissue thinning seen in the insular cortex - mild atrophy of the left frontal lobe; normal-to-mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: frontal pole (mild atrophy on the left and mild-to-moderate atrophy on the right), gyrus rectus (mild atrophy on the left and normal on the right), anterior orbital gyrus (mild atrophy on the right) and medial orbital gyrus (mild atrophy on the left) For the subcortical structures: - mild atrophy of the left hippocampus - mild atrophy of the right hippocampus - moderate bilateral atrophy of the pallidum - severe bilateral atrophy of the putamen - mild bilateral atrophy of the amygdala - mild bilateral atrophy of the ventral dc - no appreciable degenerative or atrophic changes observed in the basal forebrain - moderate-to-severe atrophy of the left thalamus and moderate atrophy of the right thalamus - mild-to-moderate atrophy of the left accumbens and moderate-to-severe atrophy of the right accumbens - moderate atrophy of the left caudate and moderate-to-severe atrophy of the right caudate
BV
FTLD_203737401_03103_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178277
On a T1-weighted brain MRI we observed: For the ventricles: - mild-to-moderate bilateral enlargement of the lateral ventricle - the 4th ventricle shows no notable changes suggestive of enlargement - moderate enlargement of the left inf. lateral ventricle and mild-to-moderate enlargement of the right inf. lateral ventricle - the external csf shows no notable changes suggestive of enlargement - no observable enlargement of the 3rd ventricle For the cerebral cortex: - no findings suggestive of atrophy are seen in the parietal lobe - no clear atrophic alterations are visible in the frontal lobe - no evident atrophy or tissue thinning seen in the insular cortex - mild atrophy of the right temporal lobe; the left temporal lobe is normal; focal volume loss observed in the following subregions: planum polare (normal on the left and mild atrophy on the right) and inf. temporal gyrus (normal on the left and mild atrophy on the right) - occipital lobe demonstrates a healthy morphology without signs of atrophy - limbic cortex appears preserved, with no observable tissue loss For the subcortical structures: - basal forebrain appears within normal limits without apparent atrophy - the pallidum shows no notable changes suggestive of atrophy - no appreciable degenerative or atrophic changes observed in the caudate - no findings suggestive of atrophy are seen in the accumbens - mild-to-moderate atrophy of the right amygdala; the left amygdala is normal - putamen appears preserved, with no observable tissue loss - no observable atrophic changes in the thalamus - no appreciable degenerative or atrophic changes observed in the ventral dc - the left hippocampus volume is borderline low - mild atrophy of the right hippocampus
BV
FTLD_203030524_03423_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450704
On a T1-weighted brain MRI we observed: For the cerebral cortex: - parietal lobe appears within normal limits without apparent atrophy - mild-to-moderate atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right) and frontal operculum (mild-to-moderate atrophy on the left and mild atrophy on the right) - moderate atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: temporal pole (moderate atrophy on the left and normal-to-mild atrophy on the right), fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and planum temporale (mild atrophy on the left) - occipital lobe appears preserved, with no observable tissue loss - mild-to-moderate atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: opercular inf. frontal gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), triangular inf. frontal gyrus (mild-to-moderate atrophy both left/right), orbital inf. frontal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), medial frontal cortex (mild atrophy on the left and normal-to-mild atrophy on the right), posterior orbital gyrus (mild-to-moderate atrophy on the left and normal on the right), gyrus rectus (mild atrophy on the left and normal on the right) and middle frontal gyrus (mild atrophy on the left) - limbic cortex appears within normal limits without apparent atrophy For the subcortical structures: - moderate atrophy of the left accumbens and mild atrophy of the right accumbens - no appreciable degenerative or atrophic changes observed in the hippocampus - no evident atrophy or tissue thinning seen in the basal forebrain - moderate atrophy of the left putamen and mild-to-moderate atrophy of the right putamen - no observable atrophic changes in the ventral dc - mild-to-moderate atrophy of the left pallidum and mild atrophy of the right pallidum - mild-to-moderate atrophy of the left amygdala; the right amygdala is normal - no findings suggestive of atrophy are seen in the thalamus - moderate atrophy of the left caudate and mild atrophy of the right caudate For the ventricles: - no clear enlargement or abnormal growth seen in the 4th ventricle - mild enlargement of the 3rd ventricle - mild enlargement of the left lateral ventricle; the right lateral ventricle is normal - mild-to-moderate enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal - mild enlargement of the external csf
PNFA
FTLD_203628476_03672_MR_Accelerated_Sagittal_IR-FSPGR_br_raw_202_I10451045
On a T1-weighted brain MRI we observed: For the ventricles: - mild-to-moderate enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle - mild-to-moderate enlargement of the 3rd ventricle - mild-to-moderate bilateral enlargement of the lateral ventricle - 4th ventricle maintains a typical volume without observable enlargement - mild enlargement of the external csf For the cerebral cortex: - no clear atrophic alterations are visible in the limbic cortex - mild atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: sup. temporal gyrus (mild atrophy on the left), planum temporale (moderate atrophy on the left and normal on the right), transverse temporal gyrus (mild atrophy on the left) and temporal pole (mild atrophy on the left and normal on the right) - occipital lobe appears preserved, with no observable tissue loss - mild atrophy of the left parietal lobe; the right parietal lobe is normal - insular cortex appears within normal limits without apparent atrophy - frontal lobe demonstrates a healthy morphology without signs of atrophy For the subcortical structures: - the left hippocampus volume is borderline low - the left hippocampus volume is borderline low - the basal forebrain shows no notable changes suggestive of atrophy - mild-to-moderate atrophy of the left thalamus and mild atrophy of the right thalamus - mild atrophy of the right amygdala; normal-to-mild atrophy of the left amygdala - moderate atrophy of the left caudate and mild-to-moderate atrophy of the right caudate - mild-to-moderate atrophy of the left ventral dc and mild atrophy of the right ventral dc - moderate-to-severe atrophy of the left pallidum and mild atrophy of the right pallidum - moderate atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens - mild-to-moderate atrophy of the left putamen and mild atrophy of the right putamen
PNFA
ADNI_135_S_4598_MR_MPRAGE_br_raw_20120320143741415_135_S144209_I291138
On a T1-weighted brain MRI we observed: For the ventricles: - no observable enlargement of the external csf - no findings suggestive of enlargement are seen in the 4th ventricle - the 3rd ventricle shows no notable changes suggestive of enlargement - inf. lateral ventricle appears to be of normal dimensions, with no observable increase in size - lateral ventricle appears within normal size limits with no apparent enlargement For the cerebral cortex: - no observable atrophic changes in the limbic cortex - occipital lobe appears within normal limits without apparent atrophy - no clear atrophic alterations are visible in the temporal lobe - no appreciable degenerative or atrophic changes observed in the frontal lobe - insular cortex appears within normal limits without apparent atrophy - parietal lobe appears within normal limits without apparent atrophy For the subcortical structures: - no observable atrophic changes in the accumbens - no evident atrophy or tissue thinning seen in the amygdala - moderate atrophy of the left hippocampus - mild atrophy of the right hippocampus - the basal forebrain shows no notable changes suggestive of atrophy - pallidum maintains a normal appearance with no observable atrophic features - no findings suggestive of atrophy are seen in the ventral dc - the thalamus shows no notable changes suggestive of atrophy - caudate appears within normal limits without apparent atrophy - no clear atrophic alterations are visible in the putamen
CN
ADNI_019_S_5012_MR_MPRAGE_br_raw_20121105133035688_113_S173252_I343916
On a T1-weighted brain MRI we observed: For the subcortical structures: - no clear atrophic alterations are visible in the pallidum - no evident atrophy or tissue thinning seen in the ventral dc - mild atrophy of the left hippocampus - no appreciable degenerative or atrophic changes observed in the amygdala - no evident atrophy or tissue thinning seen in the thalamus - putamen demonstrates a healthy morphology without signs of atrophy - no clear atrophic alterations are visible in the accumbens - no clear atrophic alterations are visible in the caudate - basal forebrain appears within normal limits without apparent atrophy For the ventricles: - mild enlargement of the 3rd ventricle - mild enlargement of the right lateral ventricle; normal-to-mild enlargement of the left lateral ventricle - mild enlargement of the external csf - mild enlargement of the 4th ventricle - no evident size increase noted in the inf. lateral ventricle For the cerebral cortex: - mild bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: central operculum (mild atrophy both left/right) and anterior insula (mild atrophy both left/right) - no appreciable degenerative or atrophic changes observed in the limbic cortex - mild atrophy of the left parietal lobe; the right parietal lobe is normal; focal volume loss observed in the following subregions: postcentral gyrus medial segment (normal on the left and mild atrophy on the right) and sup. parietal lobule (mild atrophy on the left and normal on the right) - mild atrophy of the left frontal lobe; normal-to-mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: triangular inf. frontal gyrus (mild atrophy both left/right), medial orbital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), precentral gyrus medial segment (normal on the left and mild-to-moderate atrophy on the right) and orbital inf. frontal gyrus (mild-to-moderate atrophy on the left) - mild bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: sup. temporal gyrus (mild atrophy both left/right) and fusiform gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) - no observable atrophic changes in the occipital lobe
AD
ADNI_941_S_4376_MR_MPRAGE_GRAPPA2_br_raw_20111209090238448_48_S131189_I269040
On a T1-weighted brain MRI we observed: For the ventricles: - the 4th ventricle shows no notable changes suggestive of enlargement - lateral ventricle appears within normal size limits with no apparent enlargement - the inf. lateral ventricle shows no notable changes suggestive of enlargement - the 3rd ventricle shows no notable changes suggestive of enlargement - no findings suggestive of enlargement are seen in the external csf For the subcortical structures: - no appreciable degenerative or atrophic changes observed in the hippocampus - amygdala appears within normal limits without apparent atrophy - no evident atrophy or tissue thinning seen in the thalamus - ventral dc demonstrates a healthy morphology without signs of atrophy - putamen appears within normal limits without apparent atrophy - mild atrophy of the left accumbens; the right accumbens is normal - no appreciable degenerative or atrophic changes observed in the caudate - no evident atrophy or tissue thinning seen in the pallidum - no findings suggestive of atrophy are seen in the basal forebrain For the cerebral cortex: - no observable atrophic changes in the temporal lobe - parietal lobe appears within normal limits without apparent atrophy - frontal lobe maintains a normal appearance with no observable atrophic features - no observable atrophic changes in the occipital lobe - limbic cortex maintains a normal appearance with no observable atrophic features - insular cortex maintains a normal appearance with no observable atrophic features
CN
FTLD_203515451_01151_MR_Sagittal_MP-Rage_br_raw_20230206165921554_I10181869
On a T1-weighted brain MRI we observed: For the ventricles: - no clear enlargement or abnormal growth seen in the 4th ventricle - mild enlargement of the right inf. lateral ventricle; normal-to-mild enlargement of the left inf. lateral ventricle - 3rd ventricle appears to be of normal dimensions, with no observable increase in size - no findings suggestive of enlargement are seen in the lateral ventricle - mild-to-moderate enlargement of the external csf For the cerebral cortex: - mild bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: central operculum (mild-to-moderate atrophy on the left and mild atrophy on the right) and parietal operculum (mild atrophy both left/right) - no findings suggestive of atrophy are seen in the limbic cortex - frontal lobe appears preserved, with no observable tissue loss - parietal lobe appears preserved, with no observable tissue loss - mild-to-moderate atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: middle temporal gyrus (moderate atrophy on the left and mild atrophy on the right) and temporal pole (normal on the left and mild atrophy on the right) - no appreciable degenerative or atrophic changes observed in the occipital lobe For the subcortical structures: - no findings suggestive of atrophy are seen in the pallidum - ventral dc appears preserved, with no observable tissue loss - caudate appears within normal limits without apparent atrophy - putamen appears within normal limits without apparent atrophy - no appreciable degenerative or atrophic changes observed in the basal forebrain - the left hippocampus volume is borderline low - amygdala maintains a normal appearance with no observable atrophic features - accumbens appears within normal limits without apparent atrophy - the thalamus shows no notable changes suggestive of atrophy
CN
ADNI_009_S_5224_MR_MPRAGE_br_raw_20130717152112089_161_S195460_I381184
On a T1-weighted brain MRI we observed: For the subcortical structures: - no evident atrophy or tissue thinning seen in the thalamus - no findings suggestive of atrophy are seen in the basal forebrain - no observable atrophic changes in the putamen - severe bilateral atrophy of the amygdala - mild atrophy of the right ventral dc; normal-to-mild atrophy of the left ventral dc - caudate maintains a normal appearance with no observable atrophic features - mild bilateral atrophy of the accumbens - mild atrophy of the left hippocampus - mild-to-moderate atrophy of the right hippocampus - no observable atrophic changes in the pallidum For the cerebral cortex: - mild-to-moderate atrophy of the right insular cortex; normal-to-mild atrophy of the left insular cortex; focal volume loss observed in the following subregions: posterior insula (normal-to-mild atrophy on the left and mild atrophy on the right), frontal operculum (mild atrophy on the left and normal-to-mild atrophy on the right) and central operculum (normal on the left and mild atrophy on the right) - mild-to-moderate atrophy of the right temporal lobe; normal-to-mild atrophy of the left temporal lobe; focal volume loss observed in the following subregions: temporal pole (mild-to-moderate atrophy on the left and moderate atrophy on the right), middle temporal gyrus (mild atrophy both left/right), inf. temporal gyrus (mild atrophy on the right) and transverse temporal gyrus (mild atrophy on the left) - frontal lobe appears within normal limits without apparent atrophy - mild bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: entorhinal area (mild-to-moderate atrophy both left/right) and parahippocampal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right) - the parietal lobe shows no notable changes suggestive of atrophy - no clear atrophic alterations are visible in the occipital lobe For the ventricles: - mild enlargement of the external csf - mild enlargement of the 3rd ventricle - mild enlargement of the right lateral ventricle; normal-to-mild enlargement of the left lateral ventricle - no evident size increase noted in the 4th ventricle - mild enlargement of the left inf. lateral ventricle and moderate-to-severe enlargement of the right inf. lateral ventricle
AD
FTLD_203781093_01398_MR_Sagittal_MP-Rage_br_raw_20230124211242883_I10178563
On a T1-weighted brain MRI we observed: For the cerebral cortex: - the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in lateral orbital gyrus (normal-to-mild atrophy on the left and moderate atrophy on the right), opercular inf. frontal gyrus (mild atrophy on the left), triangular inf. frontal gyrus (mild atrophy on the right) and medial frontal cortex (mild atrophy on the right) - no clear atrophic alterations are visible in the insular cortex - no evident atrophy or tissue thinning seen in the parietal lobe - no observable atrophic changes in the occipital lobe - limbic cortex appears within normal limits without apparent atrophy - no clear atrophic alterations are visible in the temporal lobe For the ventricles: - no findings suggestive of enlargement are seen in the external csf - mild-to-moderate bilateral enlargement of the lateral ventricle - no appreciable enlargement noted in the 4th ventricle - mild bilateral enlargement of the inf. lateral ventricle - 3rd ventricle maintains a typical volume without observable enlargement For the subcortical structures: - putamen demonstrates a healthy morphology without signs of atrophy - no observable atrophic changes in the basal forebrain - ventral dc appears preserved, with no observable tissue loss - amygdala demonstrates a healthy morphology without signs of atrophy - no clear atrophic alterations are visible in the hippocampus - thalamus demonstrates a healthy morphology without signs of atrophy - no appreciable degenerative or atrophic changes observed in the accumbens - no observable atrophic changes in the caudate - no appreciable degenerative or atrophic changes observed in the pallidum
CN
FTLD_203628476_03672_MR_Accelerated_Sagittal_IR-FSPGR_br_raw_202_I10451045
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no evident atrophy or tissue thinning seen in the frontal lobe - the occipital lobe shows no notable changes suggestive of atrophy - mild atrophy of the left parietal lobe; the right parietal lobe is normal - no appreciable degenerative or atrophic changes observed in the limbic cortex - no clear atrophic alterations are visible in the insular cortex - mild atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: sup. temporal gyrus (mild atrophy on the left), planum temporale (moderate atrophy on the left and normal on the right), transverse temporal gyrus (mild atrophy on the left) and temporal pole (mild atrophy on the left and normal on the right) For the ventricles: - mild-to-moderate bilateral enlargement of the lateral ventricle - mild enlargement of the external csf - mild-to-moderate enlargement of the 3rd ventricle - mild-to-moderate enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle - 4th ventricle maintains its expected proportions without signs of enlargement For the subcortical structures: - mild-to-moderate atrophy of the left ventral dc and mild atrophy of the right ventral dc - mild atrophy of the right amygdala; normal-to-mild atrophy of the left amygdala - the left hippocampus volume is borderline low - the left hippocampus volume is borderline low - basal forebrain maintains a normal appearance with no observable atrophic features - mild-to-moderate atrophy of the left thalamus and mild atrophy of the right thalamus - moderate atrophy of the left caudate and mild-to-moderate atrophy of the right caudate - moderate atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens - mild-to-moderate atrophy of the left putamen and mild atrophy of the right putamen - moderate-to-severe atrophy of the left pallidum and mild atrophy of the right pallidum
PNFA
ADNI_003_S_5165_MR_Accelerated_SAG_IR-SPGR__br_raw_20130520154957012_180_S190116_I373251
On a T1-weighted brain MRI we observed: For the ventricles: - mild enlargement of the 4th ventricle - mild enlargement of the 3rd ventricle - moderate-to-severe enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle - mild-to-moderate enlargement of the left lateral ventricle and mild enlargement of the right lateral ventricle - no appreciable enlargement noted in the external csf For the subcortical structures: - mild bilateral atrophy of the caudate - mild bilateral atrophy of the putamen - mild atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens - mild atrophy of the left thalamus; normal-to-mild atrophy of the right thalamus - the left hippocampus volume is borderline low - mild atrophy of the right hippocampus - ventral dc demonstrates a healthy morphology without signs of atrophy - pallidum appears within normal limits without apparent atrophy - basal forebrain appears within normal limits without apparent atrophy - amygdala appears preserved, with no observable tissue loss For the cerebral cortex: - mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: middle cingulate gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) - no evident atrophy or tissue thinning seen in the parietal lobe - no clear atrophic alterations are visible in the occipital lobe - mild atrophy of the right temporal lobe; the left temporal lobe is normal; focal volume loss observed in the following subregions: sup. temporal gyrus (mild-to-moderate atrophy on the right) and planum temporale (normal on the left and mild atrophy on the right) - frontal lobe appears within normal limits without apparent atrophy - mild atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and mild-to-moderate atrophy on the right), posterior insula (mild atrophy on the left and normal-to-mild atrophy on the right) and parietal operculum (mild atrophy on the left and normal-to-mild atrophy on the right)
AD
FTLD_203197205_03509_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450866
On a T1-weighted brain MRI we observed: For the cerebral cortex: - moderate atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and mild atrophy on the right), posterior insula (mild-to-moderate atrophy on the left and mild atrophy on the right) and parietal operculum (normal-to-mild atrophy on the left and mild atrophy on the right) - mild-to-moderate atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: parahippocampal gyrus (moderate atrophy on the left and normal on the right), entorhinal area (mild-to-moderate atrophy on the left and normal on the right), middle cingulate gyrus (mild atrophy on the left) and posterior cingulate gyrus (mild atrophy on the left and normal on the right) - no clear atrophic alterations are visible in the occipital lobe - parietal lobe maintains a normal appearance with no observable atrophic features - the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in medial frontal cortex (moderate atrophy on the left), gyrus rectus (mild atrophy on the left and normal-to-mild atrophy on the right), precentral gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and sup. frontal gyrus medial segment (normal on the left and mild atrophy on the right) - severe atrophy of the left temporal lobe and moderate-to-severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (mild-to-moderate atrophy both left/right), inf. temporal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), middle temporal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), fusiform gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), planum polare (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) and sup. temporal gyrus (mild atrophy on the left) For the ventricles: - 3rd ventricle maintains its expected proportions without signs of enlargement - moderate-to-severe enlargement of the left inf. lateral ventricle; normal-to-mild enlargement of the right inf. lateral ventricle - mild-to-moderate enlargement of the left lateral ventricle and mild enlargement of the right lateral ventricle - external csf appears within normal size limits with no apparent enlargement - 4th ventricle appears within normal size limits with no apparent enlargement For the subcortical structures: - no evident atrophy or tissue thinning seen in the ventral dc - no appreciable degenerative or atrophic changes observed in the caudate - moderate atrophy of the left hippocampus - mild atrophy of the right hippocampus - mild-to-moderate atrophy of the left putamen and mild atrophy of the right putamen - mild atrophy of the left accumbens; the right accumbens is normal - no evident atrophy or tissue thinning seen in the thalamus - severe atrophy of the left amygdala and moderate-to-severe atrophy of the right amygdala - mild atrophy of the left basal forebrain; the right basal forebrain is normal - mild atrophy of the left pallidum; the right pallidum is normal
SV
FTLD_203929346_03642_MR_Accelerated_Sagittal_MPRAGE_br_raw_20241_I11047637
On a T1-weighted brain MRI we observed: For the cerebral cortex: - severe atrophy of the right temporal lobe; the left temporal lobe is normal; focal volume loss observed in the following subregions: temporal pole (mild-to-moderate atrophy on the left and moderate-to-severe atrophy on the right), inf. temporal gyrus (normal-to-mild atrophy on the left and moderate-to-severe atrophy on the right), fusiform gyrus (normal-to-mild atrophy on the left and moderate atrophy on the right), middle temporal gyrus (moderate-to-severe atrophy on the right), sup. temporal gyrus (mild atrophy on the right) and planum polare (mild atrophy on the right) - frontal lobe maintains a normal appearance with no observable atrophic features - no findings suggestive of atrophy are seen in the occipital lobe - mild-to-moderate atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (mild-to-moderate atrophy on the left and moderate atrophy on the right), anterior cingulate gyrus (mild atrophy on the right) and parahippocampal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) - no evident atrophy or tissue thinning seen in the parietal lobe - mild atrophy of the right insular cortex; the left insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (mild-to-moderate atrophy on the right) and posterior insula (mild-to-moderate atrophy on the right) For the ventricles: - 4th ventricle appears to be of normal dimensions, with no observable increase in size - mild enlargement of the external csf - mild enlargement of the 3rd ventricle - mild enlargement of the left lateral ventricle and mild-to-moderate enlargement of the right lateral ventricle - mild enlargement of the left inf. lateral ventricle and severe enlargement of the right inf. lateral ventricle For the subcortical structures: - no observable atrophic changes in the basal forebrain - mild-to-moderate bilateral atrophy of the accumbens - mild atrophy of the right caudate; normal-to-mild atrophy of the left caudate - mild atrophy of the right ventral dc; the left ventral dc is normal - mild atrophy of the right thalamus; the left thalamus is normal - moderate-to-severe atrophy of the left amygdala and severe atrophy of the right amygdala - the left hippocampus volume is borderline low - moderate atrophy of the right hippocampus - moderate atrophy of the right putamen; normal-to-mild atrophy of the left putamen - mild atrophy of the left pallidum and moderate atrophy of the right pallidum
SV
FTLD_203432376_01673_MR_Sagittal_MP-Rage_br_raw_20230206145827122_I10181308
On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild atrophy of the left insular cortex and moderate atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and mild-to-moderate atrophy on the right), parietal operculum (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right) and central operculum (mild atrophy on the right) - limbic cortex appears within normal limits without apparent atrophy - mild atrophy of the right occipital lobe; normal-to-mild atrophy of the left occipital lobe; focal volume loss observed in the following subregions: inf. occipital gyrus (normal on the left and mild-to-moderate atrophy on the right) - parietal lobe demonstrates a healthy morphology without signs of atrophy - mild atrophy of the right temporal lobe; the left temporal lobe is normal; focal volume loss observed in the following subregions: fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. temporal gyrus (normal on the left and mild-to-moderate atrophy on the right), transverse temporal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right) and planum temporale (normal on the left and mild atrophy on the right) - mild atrophy of the left frontal lobe and moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: frontal pole (mild atrophy on the left and moderate atrophy on the right), middle frontal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), sup. frontal gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), medial frontal cortex (normal on the left and mild atrophy on the right), anterior orbital gyrus (normal on the left and mild atrophy on the right) and precentral gyrus (normal on the left and mild atrophy on the right) For the subcortical structures: - mild atrophy of the left pallidum and mild-to-moderate atrophy of the right pallidum - thalamus maintains a normal appearance with no observable atrophic features - hippocampus maintains a normal appearance with no observable atrophic features - ventral dc appears within normal limits without apparent atrophy - mild-to-moderate atrophy of the left accumbens and moderate atrophy of the right accumbens - mild atrophy of the right caudate; normal-to-mild atrophy of the left caudate - basal forebrain appears within normal limits without apparent atrophy - moderate bilateral atrophy of the amygdala - mild-to-moderate atrophy of the left putamen and moderate atrophy of the right putamen For the ventricles: - inf. lateral ventricle appears within normal size limits with no apparent enlargement - 3rd ventricle maintains a typical volume without observable enlargement - moderate-to-severe enlargement of the external csf - lateral ventricle maintains its expected proportions without signs of enlargement - mild enlargement of the 4th ventricle
PNFA
FTLD_203886850_03058_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177914
On a T1-weighted brain MRI we observed: For the cerebral cortex: - moderate atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (severe atrophy on the left and moderate-to-severe atrophy on the right) and frontal operculum (moderate atrophy on the left and mild-to-moderate atrophy on the right) - no findings suggestive of atrophy are seen in the temporal lobe - no evident atrophy or tissue thinning seen in the parietal lobe - moderate-to-severe atrophy of the left frontal lobe and mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: posterior orbital gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), opercular inf. frontal gyrus (mild-to-moderate atrophy both left/right), triangular inf. frontal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), medial orbital gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), sup. frontal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), sup. frontal gyrus medial segment (mild atrophy both left/right), frontal pole (mild-to-moderate atrophy on the left), orbital inf. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and gyrus rectus (mild atrophy on the left and normal on the right) - mild-to-moderate atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) and entorhinal area (mild-to-moderate atrophy on the left) - no findings suggestive of atrophy are seen in the occipital lobe For the ventricles: - 4th ventricle maintains its expected proportions without signs of enlargement - mild-to-moderate enlargement of the external csf - mild-to-moderate bilateral enlargement of the lateral ventricle - moderate-to-severe enlargement of the 3rd ventricle - severe enlargement of the left inf. lateral ventricle; normal-to-mild enlargement of the right inf. lateral ventricle For the subcortical structures: - mild atrophy of the left caudate; the right caudate is normal - the left hippocampus volume is borderline low - moderate atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens - thalamus appears within normal limits without apparent atrophy - no appreciable degenerative or atrophic changes observed in the basal forebrain - moderate atrophy of the left putamen and mild atrophy of the right putamen - mild-to-moderate atrophy of the left pallidum; normal-to-mild atrophy of the right pallidum - moderate-to-severe atrophy of the left amygdala; normal-to-mild atrophy of the right amygdala - ventral dc appears preserved, with no observable tissue loss
BV
FTLD_203764653_03356_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10450598
On a T1-weighted brain MRI we observed: For the subcortical structures: - ventral dc appears within normal limits without apparent atrophy - no findings suggestive of atrophy are seen in the accumbens - hippocampus appears within normal limits without apparent atrophy - no observable atrophic changes in the basal forebrain - pallidum demonstrates a healthy morphology without signs of atrophy - putamen maintains a normal appearance with no observable atrophic features - amygdala maintains a normal appearance with no observable atrophic features - no evident atrophy or tissue thinning seen in the thalamus - no findings suggestive of atrophy are seen in the caudate For the cerebral cortex: - no observable atrophic changes in the limbic cortex - no clear atrophic alterations are visible in the temporal lobe - no observable atrophic changes in the occipital lobe - insular cortex maintains a normal appearance with no observable atrophic features - frontal lobe maintains a normal appearance with no observable atrophic features - no observable atrophic changes in the parietal lobe For the ventricles: - mild-to-moderate enlargement of the 3rd ventricle - no clear enlargement or abnormal growth seen in the external csf - no clear enlargement or abnormal growth seen in the inf. lateral ventricle - lateral ventricle maintains its expected proportions without signs of enlargement - no appreciable enlargement noted in the 4th ventricle
BV
ADNI_022_S_4266_MR_MPRAGE_GRAPPA2_br_raw_20111117152723220_140_S130070_I267457
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild atrophy of the right pallidum; normal-to-mild atrophy of the left pallidum - hippocampus demonstrates a healthy morphology without signs of atrophy - the putamen shows no notable changes suggestive of atrophy - the accumbens shows no notable changes suggestive of atrophy - no appreciable degenerative or atrophic changes observed in the amygdala - caudate demonstrates a healthy morphology without signs of atrophy - basal forebrain appears preserved, with no observable tissue loss - ventral dc maintains a normal appearance with no observable atrophic features - thalamus maintains a normal appearance with no observable atrophic features For the cerebral cortex: - temporal lobe maintains a normal appearance with no observable atrophic features - the occipital lobe shows no notable changes suggestive of atrophy - no appreciable degenerative or atrophic changes observed in the parietal lobe - mild bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: posterior cingulate gyrus (mild atrophy both left/right) and parahippocampal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) - frontal lobe appears preserved, with no observable tissue loss - insular cortex maintains a normal appearance with no observable atrophic features For the ventricles: - inf. lateral ventricle appears within normal size limits with no apparent enlargement - no findings suggestive of enlargement are seen in the 4th ventricle - lateral ventricle maintains a typical volume without observable enlargement - no evident size increase noted in the 3rd ventricle - no observable enlargement of the external csf
CN
FTLD_203937006_01603_MR_Sagittal_MP-Rage_br_raw_20230206145018960_I10181259
On a T1-weighted brain MRI we observed: For the cerebral cortex: - temporal lobe appears preserved, with no observable tissue loss - mild atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: opercular inf. frontal gyrus (mild atrophy both left/right), orbital inf. frontal gyrus (mild atrophy on the left and normal on the right), posterior orbital gyrus (mild atrophy on the left and normal on the right), gyrus rectus (mild atrophy on the left) and sup. frontal gyrus (mild atrophy on the left) - parietal lobe appears within normal limits without apparent atrophy - no appreciable degenerative or atrophic changes observed in the occipital lobe - mild-to-moderate atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (severe atrophy on the left and moderate atrophy on the right) and frontal operculum (mild atrophy on the left) - no evident atrophy or tissue thinning seen in the limbic cortex For the ventricles: - mild-to-moderate enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal - no findings suggestive of enlargement are seen in the 4th ventricle - no evident size increase noted in the 3rd ventricle - mild enlargement of the left lateral ventricle; the right lateral ventricle is normal - no evident size increase noted in the external csf For the subcortical structures: - no appreciable degenerative or atrophic changes observed in the basal forebrain - the thalamus shows no notable changes suggestive of atrophy - amygdala appears preserved, with no observable tissue loss - no findings suggestive of atrophy are seen in the ventral dc - the left hippocampus volume is borderline low - pallidum demonstrates a healthy morphology without signs of atrophy - mild atrophy of the left putamen; the right putamen is normal - mild atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens - no evident atrophy or tissue thinning seen in the caudate
PNFA
FTLD_203590286_02689_MR_Accelerated_Sagittal_IR-FSPGR_br_raw_202_I10176953
On a T1-weighted brain MRI we observed: For the cerebral cortex: - frontal lobe maintains a normal appearance with no observable atrophic features - the occipital lobe shows no notable changes suggestive of atrophy - no clear atrophic alterations are visible in the limbic cortex - the insular cortex shows no notable changes suggestive of atrophy - parietal lobe demonstrates a healthy morphology without signs of atrophy - mild atrophy of the right temporal lobe; normal-to-mild atrophy of the left temporal lobe; focal volume loss observed in the following subregions: temporal pole (mild atrophy both left/right) and sup. temporal gyrus (mild atrophy on the left and normal on the right) For the subcortical structures: - mild atrophy of the left accumbens; the right accumbens is normal - the putamen shows no notable changes suggestive of atrophy - pallidum demonstrates a healthy morphology without signs of atrophy - thalamus appears preserved, with no observable tissue loss - no observable atrophic changes in the ventral dc - mild bilateral atrophy of the caudate - basal forebrain appears preserved, with no observable tissue loss - no appreciable degenerative or atrophic changes observed in the hippocampus - amygdala maintains a normal appearance with no observable atrophic features For the ventricles: - no findings suggestive of enlargement are seen in the lateral ventricle - no appreciable enlargement noted in the 4th ventricle - no evident size increase noted in the 3rd ventricle - no evident size increase noted in the external csf - no clear enlargement or abnormal growth seen in the inf. lateral ventricle
PNFA
ADNI_007_S_2106_MR_Accelerated_SAG_IR-SPGR__br_raw_20131021160539689_118_S204433_I395325
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no evident atrophy or tissue thinning seen in the frontal lobe - limbic cortex maintains a normal appearance with no observable atrophic features - the temporal lobe shows no notable changes suggestive of atrophy - parietal lobe maintains a normal appearance with no observable atrophic features - occipital lobe demonstrates a healthy morphology without signs of atrophy - no appreciable degenerative or atrophic changes observed in the insular cortex For the ventricles: - lateral ventricle appears to be of normal dimensions, with no observable increase in size - no appreciable enlargement noted in the inf. lateral ventricle - 4th ventricle maintains a typical volume without observable enlargement - no findings suggestive of enlargement are seen in the external csf - no evident size increase noted in the 3rd ventricle For the subcortical structures: - mild bilateral atrophy of the caudate - no observable atrophic changes in the basal forebrain - mild-to-moderate atrophy of the left hippocampus - mild atrophy of the right hippocampus - pallidum maintains a normal appearance with no observable atrophic features - no findings suggestive of atrophy are seen in the putamen - no findings suggestive of atrophy are seen in the thalamus - no observable atrophic changes in the accumbens - mild-to-moderate atrophy of the left amygdala and mild atrophy of the right amygdala - mild atrophy of the left ventral dc; normal-to-mild atrophy of the right ventral dc
AD
ADNI_131_S_1301_MR_MPR__GradWarp__B1_Correction__N3__Scaled_Br_20070801190324220_S26899_I63793
On a T1-weighted brain MRI we observed: For the subcortical structures: - no observable atrophic changes in the ventral dc - basal forebrain maintains a normal appearance with no observable atrophic features - no clear atrophic alterations are visible in the hippocampus - pallidum demonstrates a healthy morphology without signs of atrophy - no clear atrophic alterations are visible in the accumbens - putamen maintains a normal appearance with no observable atrophic features - amygdala maintains a normal appearance with no observable atrophic features - caudate appears preserved, with no observable tissue loss - no clear atrophic alterations are visible in the thalamus For the ventricles: - external csf maintains its expected proportions without signs of enlargement - no evident size increase noted in the inf. lateral ventricle - no clear enlargement or abnormal growth seen in the 4th ventricle - no evident size increase noted in the lateral ventricle - mild enlargement of the 3rd ventricle For the cerebral cortex: - mild bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: planum polare (normal-to-mild atrophy on the left and mild atrophy on the right), inf. temporal gyrus (mild-to-moderate atrophy on the right) and fusiform gyrus (mild atrophy on the left and normal on the right) - no clear atrophic alterations are visible in the insular cortex - no evident atrophy or tissue thinning seen in the parietal lobe - mild bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: frontal pole (mild atrophy on the left and normal-to-mild atrophy on the right), sup. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), precentral gyrus (mild atrophy on the right) and opercular inf. frontal gyrus (normal on the left and mild atrophy on the right) - limbic cortex maintains a normal appearance with no observable atrophic features - no findings suggestive of atrophy are seen in the occipital lobe
CN
FTLD_203995405_01509_MR_Sagittal_MP-Rage_br_raw_20230206173212581_I10182118
On a T1-weighted brain MRI we observed: For the ventricles: - mild enlargement of the 3rd ventricle - no findings suggestive of enlargement are seen in the 4th ventricle - severe enlargement of the external csf - mild enlargement of the left lateral ventricle; normal-to-mild enlargement of the right lateral ventricle - moderate bilateral enlargement of the inf. lateral ventricle For the cerebral cortex: - parietal lobe maintains a normal appearance with no observable atrophic features - mild-to-moderate bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: frontal pole (mild atrophy on the left and mild-to-moderate atrophy on the right), medial frontal cortex (mild atrophy on the left and mild-to-moderate atrophy on the right), medial orbital gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), posterior orbital gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), gyrus rectus (mild atrophy both left/right), sup. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), middle frontal gyrus (mild-to-moderate atrophy on the left) and lateral orbital gyrus (mild atrophy on the right) - mild atrophy of the left insular cortex and mild-to-moderate atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and severe atrophy on the right) and posterior insula (mild-to-moderate atrophy both left/right) - moderate atrophy of the left limbic cortex and moderate-to-severe atrophy of the right limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild-to-moderate atrophy on the left and moderate atrophy on the right), entorhinal area (mild-to-moderate atrophy both left/right), parahippocampal gyrus (mild-to-moderate atrophy both left/right) and middle cingulate gyrus (mild atrophy on the right) - no findings suggestive of atrophy are seen in the occipital lobe - severe bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: temporal pole (severe atrophy both left/right), inf. temporal gyrus (mild-to-moderate atrophy on the left and moderate atrophy on the right), middle temporal gyrus (mild atrophy on the left and moderate-to-severe atrophy on the right), fusiform gyrus (mild-to-moderate atrophy both left/right), planum polare (mild-to-moderate atrophy on the left and mild atrophy on the right) and sup. temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) For the subcortical structures: - mild-to-moderate atrophy of the left caudate and moderate atrophy of the right caudate - mild bilateral atrophy of the thalamus - moderate-to-severe bilateral atrophy of the accumbens - mild bilateral atrophy of the pallidum - no clear atrophic alterations are visible in the basal forebrain - no clear atrophic alterations are visible in the ventral dc - mild-to-moderate bilateral atrophy of the putamen - severe bilateral atrophy of the amygdala - moderate-to-severe atrophy of the left hippocampus - moderate-to-severe atrophy of the right hippocampus
BV
FTLD_203260125_02526_MR_Sagittal_MP-Rage_br_raw_20230206161248652_I10181566
On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: fusiform gyrus (mild-to-moderate atrophy both left/right), transverse temporal gyrus (mild atrophy on the right), planum temporale (normal-to-mild atrophy on the left and mild atrophy on the right) and sup. temporal gyrus (mild atrophy on the right) - no observable atrophic changes in the occipital lobe - mild bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: frontal operculum (mild atrophy both left/right) and parietal operculum (mild atrophy on the left and normal-to-mild atrophy on the right) - no findings suggestive of atrophy are seen in the parietal lobe - limbic cortex demonstrates a healthy morphology without signs of atrophy - mild-to-moderate atrophy of the left frontal lobe and moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: precentral gyrus medial segment (mild atrophy on the left and mild-to-moderate atrophy on the right), sup. frontal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), precentral gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), supplementary motor cortex (mild atrophy both left/right), middle frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), lateral orbital gyrus (mild atrophy on the left and normal on the right), gyrus rectus (mild atrophy on the left and normal on the right), medial frontal cortex (mild atrophy on the left) and sup. frontal gyrus medial segment (normal on the left and mild atrophy on the right) For the ventricles: - moderate bilateral enlargement of the inf. lateral ventricle - mild enlargement of the left lateral ventricle and mild-to-moderate enlargement of the right lateral ventricle - mild-to-moderate enlargement of the external csf - moderate enlargement of the 3rd ventricle - mild enlargement of the 4th ventricle For the subcortical structures: - the ventral dc shows no notable changes suggestive of atrophy - mild bilateral atrophy of the caudate - the pallidum shows no notable changes suggestive of atrophy - mild atrophy of the right accumbens; normal-to-mild atrophy of the left accumbens - amygdala maintains a normal appearance with no observable atrophic features - basal forebrain maintains a normal appearance with no observable atrophic features - no clear atrophic alterations are visible in the hippocampus - putamen demonstrates a healthy morphology without signs of atrophy - mild bilateral atrophy of the thalamus
PNFA
ADNI_137_S_4466_MR_MPRAGE_br_raw_20120130113126300_18_S138527_I280773
On a T1-weighted brain MRI we observed: For the cerebral cortex: - parietal lobe appears within normal limits without apparent atrophy - no findings suggestive of atrophy are seen in the insular cortex - no findings suggestive of atrophy are seen in the temporal lobe - limbic cortex demonstrates a healthy morphology without signs of atrophy - the frontal lobe shows no notable changes suggestive of atrophy - the occipital lobe shows no notable changes suggestive of atrophy For the subcortical structures: - the left hippocampus volume is borderline low - no findings suggestive of atrophy are seen in the putamen - basal forebrain maintains a normal appearance with no observable atrophic features - accumbens appears preserved, with no observable tissue loss - amygdala appears preserved, with no observable tissue loss - caudate maintains a normal appearance with no observable atrophic features - no clear atrophic alterations are visible in the ventral dc - no evident atrophy or tissue thinning seen in the thalamus - mild bilateral atrophy of the pallidum For the ventricles: - no findings suggestive of enlargement are seen in the external csf - the lateral ventricle shows no notable changes suggestive of enlargement - 4th ventricle appears within normal size limits with no apparent enlargement - mild enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal - mild enlargement of the 3rd ventricle
CN
FTLD_203411700_03001_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450139
On a T1-weighted brain MRI we observed: For the ventricles: - no clear enlargement or abnormal growth seen in the inf. lateral ventricle - 4th ventricle maintains its expected proportions without signs of enlargement - 3rd ventricle maintains a typical volume without observable enlargement - mild enlargement of the external csf - no findings suggestive of enlargement are seen in the lateral ventricle For the cerebral cortex: - the occipital lobe shows no notable changes suggestive of atrophy - mild atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (normal on the left and mild atrophy on the right) - mild atrophy of the left frontal lobe and mild-to-moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (mild atrophy on the left and moderate atrophy on the right), medial orbital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), opercular inf. frontal gyrus (mild atrophy on the left and normal on the right) and posterior orbital gyrus (normal on the left and mild atrophy on the right) - temporal lobe appears within normal limits without apparent atrophy - the insular cortex shows no notable changes suggestive of atrophy - parietal lobe demonstrates a healthy morphology without signs of atrophy For the subcortical structures: - ventral dc appears within normal limits without apparent atrophy - mild atrophy of the left caudate and mild-to-moderate atrophy of the right caudate - thalamus demonstrates a healthy morphology without signs of atrophy - no appreciable degenerative or atrophic changes observed in the hippocampus - no evident atrophy or tissue thinning seen in the amygdala - no appreciable degenerative or atrophic changes observed in the basal forebrain - accumbens maintains a normal appearance with no observable atrophic features - mild atrophy of the right putamen; normal-to-mild atrophy of the left putamen - no evident atrophy or tissue thinning seen in the pallidum
PNFA
FTLD_203792827_02729_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10176876
On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild-to-moderate atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (moderate atrophy on the left and mild atrophy on the right) and parahippocampal gyrus (mild atrophy on the left) - no clear atrophic alterations are visible in the parietal lobe - moderate atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy on the left and mild atrophy on the right), middle temporal gyrus (moderate-to-severe atrophy on the left) and planum polare (normal-to-mild atrophy on the left and mild atrophy on the right) - moderate-to-severe atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (severe atrophy on the left and normal-to-mild atrophy on the right), frontal operculum (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), central operculum (mild atrophy both left/right) and parietal operculum (mild atrophy on the left) - severe atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: triangular inf. frontal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), opercular inf. frontal gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), middle frontal gyrus (moderate atrophy on the left), sup. frontal gyrus (moderate atrophy on the left), lateral orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), orbital inf. frontal gyrus (mild atrophy on the left), posterior orbital gyrus (mild atrophy on the left and normal on the right), precentral gyrus (mild atrophy on the left) and sup. frontal gyrus medial segment (mild atrophy on the left) - no observable atrophic changes in the occipital lobe For the ventricles: - moderate-to-severe enlargement of the left lateral ventricle and severe enlargement of the right lateral ventricle - no clear enlargement or abnormal growth seen in the 4th ventricle - moderate-to-severe enlargement of the external csf - moderate-to-severe enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle - no appreciable enlargement noted in the 3rd ventricle For the subcortical structures: - moderate-to-severe atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens - moderate atrophy of the left pallidum and mild atrophy of the right pallidum - mild atrophy of the left hippocampus - mild atrophy of the right hippocampus - moderate-to-severe atrophy of the left amygdala and mild-to-moderate atrophy of the right amygdala - basal forebrain demonstrates a healthy morphology without signs of atrophy - mild bilateral atrophy of the ventral dc - severe atrophy of the left putamen and mild-to-moderate atrophy of the right putamen - mild atrophy of the left thalamus; the right thalamus is normal - severe atrophy of the left caudate and moderate atrophy of the right caudate
BV
ADNI_128_S_1148_MR_MPRAGE_br_raw_20090929170758531_100_S74323_I155880
On a T1-weighted brain MRI we observed: For the ventricles: - no evident size increase noted in the external csf - 4th ventricle maintains a typical volume without observable enlargement - mild-to-moderate enlargement of the left lateral ventricle and moderate enlargement of the right lateral ventricle - mild enlargement of the 3rd ventricle - moderate-to-severe enlargement of the left inf. lateral ventricle and severe enlargement of the right inf. lateral ventricle For the cerebral cortex: - no evident atrophy or tissue thinning seen in the occipital lobe - no observable atrophic changes in the parietal lobe - mild atrophy of the left temporal lobe and mild-to-moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: middle temporal gyrus (normal-to-mild atrophy on the left and moderate atrophy on the right), fusiform gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and planum polare (normal on the left and mild atrophy on the right) - mild atrophy of the right insular cortex; normal-to-mild atrophy of the left insular cortex; focal volume loss observed in the following subregions: frontal operculum (mild atrophy both left/right), anterior insula (mild atrophy on the left and normal-to-mild atrophy on the right) and posterior insula (normal-to-mild atrophy on the left and mild atrophy on the right) - limbic cortex maintains a normal appearance with no observable atrophic features - mild atrophy of the right frontal lobe; the left frontal lobe is normal; focal volume loss observed in the following subregions: medial frontal cortex (mild-to-moderate atrophy on the left and normal on the right) and precentral gyrus (mild atrophy on the right) For the subcortical structures: - mild atrophy of the left caudate and mild-to-moderate atrophy of the right caudate - moderate-to-severe atrophy of the left amygdala and severe atrophy of the right amygdala - mild atrophy of the right accumbens; normal-to-mild atrophy of the left accumbens - no findings suggestive of atrophy are seen in the ventral dc - mild bilateral atrophy of the putamen - mild atrophy of the left hippocampus - moderate atrophy of the right hippocampus - the basal forebrain shows no notable changes suggestive of atrophy - mild atrophy of the left pallidum; normal-to-mild atrophy of the right pallidum - thalamus appears within normal limits without apparent atrophy
AD
FTLD_203644572_03274_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10176939
On a T1-weighted brain MRI we observed: For the subcortical structures: - the basal forebrain shows no notable changes suggestive of atrophy - mild atrophy of the left thalamus; the right thalamus is normal - hippocampus appears within normal limits without apparent atrophy - no observable atrophic changes in the ventral dc - mild bilateral atrophy of the pallidum - mild-to-moderate bilateral atrophy of the caudate - mild bilateral atrophy of the accumbens - mild-to-moderate atrophy of the left putamen and mild atrophy of the right putamen - mild-to-moderate atrophy of the left amygdala and mild atrophy of the right amygdala For the ventricles: - no observable enlargement of the 4th ventricle - no clear enlargement or abnormal growth seen in the 3rd ventricle - no observable enlargement of the inf. lateral ventricle - lateral ventricle appears within normal size limits with no apparent enlargement - severe enlargement of the external csf For the cerebral cortex: - mild atrophy of the left parietal lobe; normal-to-mild atrophy of the right parietal lobe; focal volume loss observed in the following subregions: postcentral gyrus medial segment (mild atrophy both left/right), precuneus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) and sup. parietal lobule (mild atrophy on the left and normal on the right) - no appreciable degenerative or atrophic changes observed in the limbic cortex - mild atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (mild atrophy both left/right) and central operculum (mild atrophy on the left) - severe atrophy of the left frontal lobe and moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), sup. frontal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), frontal pole (mild atrophy on the left and mild-to-moderate atrophy on the right), precentral gyrus (mild atrophy both left/right), sup. frontal gyrus medial segment (mild atrophy both left/right), opercular inf. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), precentral gyrus medial segment (mild atrophy on the left and normal-to-mild atrophy on the right) and supplementary motor cortex (mild atrophy on the left and normal-to-mild atrophy on the right) - mild atrophy of the left temporal lobe; normal-to-mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate atrophy on the left and mild-to-moderate atrophy on the right) - occipital lobe maintains a normal appearance with no observable atrophic features
PNFA
FTLD_203307240_03040_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10177390
On a T1-weighted brain MRI we observed: For the subcortical structures: - putamen maintains a normal appearance with no observable atrophic features - no evident atrophy or tissue thinning seen in the caudate - mild atrophy of the left hippocampus - no findings suggestive of atrophy are seen in the accumbens - moderate-to-severe atrophy of the left amygdala and mild-to-moderate atrophy of the right amygdala - basal forebrain appears preserved, with no observable tissue loss - no evident atrophy or tissue thinning seen in the thalamus - mild atrophy of the left pallidum; the right pallidum is normal - mild atrophy of the left ventral dc; the right ventral dc is normal For the cerebral cortex: - frontal lobe appears within normal limits without apparent atrophy - occipital lobe demonstrates a healthy morphology without signs of atrophy - mild atrophy of the left limbic cortex; normal-to-mild atrophy of the right limbic cortex; focal volume loss observed in the following subregions: entorhinal area (mild atrophy on the left and normal-to-mild atrophy on the right) - mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and normal on the right) - no observable atrophic changes in the parietal lobe - severe atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (severe atrophy on the left and mild atrophy on the right), fusiform gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), inf. temporal gyrus (moderate atrophy on the left), planum polare (mild-to-moderate atrophy on the left and normal on the right), sup. temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), transverse temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), planum temporale (normal on the left and mild atrophy on the right) and middle temporal gyrus (mild atrophy on the left) For the ventricles: - moderate-to-severe enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal - the 4th ventricle shows no notable changes suggestive of enlargement - no evident size increase noted in the 3rd ventricle - mild enlargement of the left lateral ventricle; the right lateral ventricle is normal - no clear enlargement or abnormal growth seen in the external csf
SV
FTLD_203375744_03447_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450757
On a T1-weighted brain MRI we observed: For the subcortical structures: - basal forebrain appears preserved, with no observable tissue loss - the ventral dc shows no notable changes suggestive of atrophy - mild-to-moderate atrophy of the left pallidum; the right pallidum is normal - mild-to-moderate atrophy of the left accumbens and mild atrophy of the right accumbens - severe bilateral atrophy of the amygdala - moderate-to-severe atrophy of the left putamen and mild atrophy of the right putamen - thalamus appears within normal limits without apparent atrophy - moderate atrophy of the left hippocampus - mild atrophy of the right hippocampus - mild-to-moderate atrophy of the left caudate; normal-to-mild atrophy of the right caudate For the cerebral cortex: - occipital lobe maintains a normal appearance with no observable atrophic features - frontal lobe appears within normal limits without apparent atrophy - severe atrophy of the left temporal lobe and moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (severe atrophy both left/right), middle temporal gyrus (moderate-to-severe atrophy on the left and normal-to-mild atrophy on the right), fusiform gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), planum temporale (mild-to-moderate atrophy on the left and normal on the right), inf. temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and sup. temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) - mild-to-moderate atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: posterior insula (mild-to-moderate atrophy on the left and mild atrophy on the right), anterior insula (moderate atrophy on the left and normal on the right) and central operculum (mild atrophy on the left) - parietal lobe appears within normal limits without apparent atrophy - mild-to-moderate atrophy of the left limbic cortex; normal-to-mild atrophy of the right limbic cortex; focal volume loss observed in the following subregions: parahippocampal gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), middle cingulate gyrus (mild atrophy on the left), entorhinal area (mild atrophy on the left and normal-to-mild atrophy on the right) and anterior cingulate gyrus (mild atrophy on the left) For the ventricles: - severe enlargement of the left inf. lateral ventricle and moderate enlargement of the right inf. lateral ventricle - 3rd ventricle appears within normal size limits with no apparent enlargement - mild-to-moderate enlargement of the left lateral ventricle and mild enlargement of the right lateral ventricle - mild enlargement of the external csf - the 4th ventricle shows no notable changes suggestive of enlargement
SV
FTLD_203250302_03205_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178289
On a T1-weighted brain MRI we observed: For the ventricles: - mild-to-moderate enlargement of the left lateral ventricle and mild enlargement of the right lateral ventricle - 3rd ventricle maintains a typical volume without observable enlargement - mild enlargement of the external csf - 4th ventricle appears within normal size limits with no apparent enlargement - moderate-to-severe enlargement of the right inf. lateral ventricle; the left inf. lateral ventricle is normal For the cerebral cortex: - parietal lobe maintains a normal appearance with no observable atrophic features - no observable atrophic changes in the occipital lobe - mild-to-moderate atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the left and moderate atrophy on the right) and entorhinal area (normal on the left and mild atrophy on the right) - moderate atrophy of the left insular cortex and moderate-to-severe atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (severe atrophy both left/right), frontal operculum (mild atrophy both left/right) and posterior insula (normal-to-mild atrophy on the left and mild atrophy on the right) - mild atrophy of the right temporal lobe; normal-to-mild atrophy of the left temporal lobe; focal volume loss observed in the following subregions: temporal pole (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right) - moderate-to-severe atrophy of the right frontal lobe; normal-to-mild atrophy of the left frontal lobe; focal volume loss observed in the following subregions: posterior orbital gyrus (moderate atrophy both left/right), medial orbital gyrus (mild-to-moderate atrophy on the left and moderate-to-severe atrophy on the right), triangular inf. frontal gyrus (mild-to-moderate atrophy both left/right), orbital inf. frontal gyrus (mild atrophy both left/right), gyrus rectus (normal-to-mild atrophy on the left and mild atrophy on the right), opercular inf. frontal gyrus (mild-to-moderate atrophy on the right), medial frontal cortex (normal-to-mild atrophy on the left and mild atrophy on the right), sup. frontal gyrus medial segment (mild atrophy on the left and normal-to-mild atrophy on the right), middle frontal gyrus (normal on the left and mild atrophy on the right) and lateral orbital gyrus (normal on the left and mild atrophy on the right) For the subcortical structures: - mild-to-moderate atrophy of the right amygdala; normal-to-mild atrophy of the left amygdala - the hippocampus shows no notable changes suggestive of atrophy - no clear atrophic alterations are visible in the thalamus - no observable atrophic changes in the ventral dc - mild atrophy of the left accumbens and moderate atrophy of the right accumbens - mild atrophy of the left putamen and mild-to-moderate atrophy of the right putamen - mild atrophy of the left caudate and mild-to-moderate atrophy of the right caudate - mild atrophy of the right pallidum; the left pallidum is normal - basal forebrain maintains a normal appearance with no observable atrophic features
BV
FTLD_203186693_03398_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450669
On a T1-weighted brain MRI we observed: For the subcortical structures: - accumbens demonstrates a healthy morphology without signs of atrophy - no observable atrophic changes in the hippocampus - the caudate shows no notable changes suggestive of atrophy - no evident atrophy or tissue thinning seen in the amygdala - pallidum appears within normal limits without apparent atrophy - no evident atrophy or tissue thinning seen in the putamen - no appreciable degenerative or atrophic changes observed in the ventral dc - the thalamus shows no notable changes suggestive of atrophy - no appreciable degenerative or atrophic changes observed in the basal forebrain For the cerebral cortex: - limbic cortex demonstrates a healthy morphology without signs of atrophy - temporal lobe maintains a normal appearance with no observable atrophic features - parietal lobe appears within normal limits without apparent atrophy - the insular cortex shows no notable changes suggestive of atrophy - no appreciable degenerative or atrophic changes observed in the frontal lobe - occipital lobe demonstrates a healthy morphology without signs of atrophy For the ventricles: - no clear enlargement or abnormal growth seen in the 3rd ventricle - lateral ventricle appears within normal size limits with no apparent enlargement - no clear enlargement or abnormal growth seen in the 4th ventricle - no clear enlargement or abnormal growth seen in the external csf - no evident size increase noted in the inf. lateral ventricle
CN
FTLD_203920762_02262_MR_Sagittal_MP-Rage_br_raw_20230124212703655_I10178645
On a T1-weighted brain MRI we observed: For the subcortical structures: - the ventral dc shows no notable changes suggestive of atrophy - putamen appears within normal limits without apparent atrophy - no clear atrophic alterations are visible in the accumbens - no evident atrophy or tissue thinning seen in the amygdala - basal forebrain appears preserved, with no observable tissue loss - no evident atrophy or tissue thinning seen in the hippocampus - no findings suggestive of atrophy are seen in the caudate - pallidum demonstrates a healthy morphology without signs of atrophy - the thalamus shows no notable changes suggestive of atrophy For the ventricles: - no clear enlargement or abnormal growth seen in the 4th ventricle - the lateral ventricle shows no notable changes suggestive of enlargement - no observable enlargement of the inf. lateral ventricle - no clear enlargement or abnormal growth seen in the 3rd ventricle - the external csf shows no notable changes suggestive of enlargement For the cerebral cortex: - temporal lobe demonstrates a healthy morphology without signs of atrophy - no evident atrophy or tissue thinning seen in the limbic cortex - the parietal lobe shows no notable changes suggestive of atrophy - mild atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: lateral orbital gyrus (mild atrophy on the left), gyrus rectus (mild atrophy on the left and normal on the right), medial orbital gyrus (mild atrophy on the right) and precentral gyrus medial segment (mild atrophy on the left) - insular cortex appears within normal limits without apparent atrophy - no observable atrophic changes in the occipital lobe
CN
ADNI_037_S_5162_MR_MPRAGE_br_raw_20130503091904515_4_S188623_I369977
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild atrophy of the right amygdala; the left amygdala is normal - the basal forebrain shows no notable changes suggestive of atrophy - ventral dc appears within normal limits without apparent atrophy - the left hippocampus volume is borderline low - the left hippocampus volume is borderline low - mild atrophy of the left putamen; normal-to-mild atrophy of the right putamen - accumbens demonstrates a healthy morphology without signs of atrophy - mild atrophy of the right caudate; the left caudate is normal - thalamus appears within normal limits without apparent atrophy - no evident atrophy or tissue thinning seen in the pallidum For the cerebral cortex: - no clear atrophic alterations are visible in the occipital lobe - no clear atrophic alterations are visible in the frontal lobe - no observable atrophic changes in the parietal lobe - mild bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: central operculum (mild atrophy both left/right) and posterior insula (normal on the left and mild atrophy on the right) - no observable atrophic changes in the limbic cortex - mild bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: planum temporale (normal-to-mild atrophy on the left and mild atrophy on the right), middle temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), temporal pole (normal on the left and mild atrophy on the right) and planum polare (mild atrophy on the left and normal on the right) For the ventricles: - mild bilateral enlargement of the inf. lateral ventricle - no evident size increase noted in the 4th ventricle - mild enlargement of the external csf - mild-to-moderate enlargement of the 3rd ventricle - lateral ventricle appears to be of normal dimensions, with no observable increase in size
AD
ADNI_010_S_0067_MR_MPR____N3__Scaled_Br_20080308121553394_S10344_I96211
On a T1-weighted brain MRI we observed: For the cerebral cortex: - limbic cortex maintains a normal appearance with no observable atrophic features - parietal lobe demonstrates a healthy morphology without signs of atrophy - insular cortex demonstrates a healthy morphology without signs of atrophy - no evident atrophy or tissue thinning seen in the temporal lobe - no appreciable degenerative or atrophic changes observed in the frontal lobe - the occipital lobe shows no notable changes suggestive of atrophy For the ventricles: - no findings suggestive of enlargement are seen in the inf. lateral ventricle - no evident size increase noted in the 4th ventricle - no findings suggestive of enlargement are seen in the 3rd ventricle - no observable enlargement of the lateral ventricle - no findings suggestive of enlargement are seen in the external csf For the subcortical structures: - no observable atrophic changes in the caudate - mild bilateral atrophy of the accumbens - basal forebrain appears within normal limits without apparent atrophy - no observable atrophic changes in the putamen - no clear atrophic alterations are visible in the thalamus - amygdala demonstrates a healthy morphology without signs of atrophy - no clear atrophic alterations are visible in the hippocampus - the pallidum shows no notable changes suggestive of atrophy - no findings suggestive of atrophy are seen in the ventral dc
CN
ADNI_014_S_4039_MR_MPRAGE_br_raw_20110603075656539_127_S110533_I238745
On a T1-weighted brain MRI we observed: For the subcortical structures: - the left hippocampus volume is borderline low - mild atrophy of the right hippocampus - mild atrophy of the left amygdala and moderate atrophy of the right amygdala - no findings suggestive of atrophy are seen in the ventral dc - mild atrophy of the right pallidum; the left pallidum is normal - basal forebrain appears within normal limits without apparent atrophy - mild bilateral atrophy of the caudate - mild atrophy of the right putamen; normal-to-mild atrophy of the left putamen - mild atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens - mild atrophy of the right thalamus; normal-to-mild atrophy of the left thalamus For the cerebral cortex: - no observable atrophic changes in the frontal lobe - mild-to-moderate bilateral atrophy of the parietal lobe; focal volume loss observed in the following subregions: precuneus (moderate atrophy on the left and mild-to-moderate atrophy on the right), angular gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right) and supramarginal gyrus (mild atrophy on the left and normal on the right) - mild atrophy of the right insular cortex; normal-to-mild atrophy of the left insular cortex; focal volume loss observed in the following subregions: central operculum (mild atrophy on the left and mild-to-moderate atrophy on the right) - no observable atrophic changes in the occipital lobe - mild-to-moderate atrophy of the left temporal lobe and moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: middle temporal gyrus (mild atrophy both left/right), fusiform gyrus (mild atrophy both left/right), sup. temporal gyrus (mild atrophy both left/right), transverse temporal gyrus (normal on the left and mild atrophy on the right) and temporal pole (normal on the left and mild atrophy on the right) - limbic cortex appears within normal limits without apparent atrophy For the ventricles: - mild-to-moderate enlargement of the left inf. lateral ventricle and moderate-to-severe enlargement of the right inf. lateral ventricle - mild enlargement of the 3rd ventricle - moderate enlargement of the external csf - mild enlargement of the left lateral ventricle and moderate enlargement of the right lateral ventricle - no observable enlargement of the 4th ventricle
AD
FTLD_203163034_02436_MR_Sagittal_MP-Rage_br_raw_20230209101942649_I10183429
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild-to-moderate atrophy of the left accumbens and mild atrophy of the right accumbens - mild atrophy of the left amygdala; the right amygdala is normal - hippocampus maintains a normal appearance with no observable atrophic features - mild atrophy of the left putamen; normal-to-mild atrophy of the right putamen - no clear atrophic alterations are visible in the thalamus - mild bilateral atrophy of the caudate - basal forebrain appears within normal limits without apparent atrophy - mild bilateral atrophy of the pallidum - no appreciable degenerative or atrophic changes observed in the ventral dc For the ventricles: - no observable enlargement of the lateral ventricle - no clear enlargement or abnormal growth seen in the 3rd ventricle - mild-to-moderate enlargement of the external csf - 4th ventricle maintains its expected proportions without signs of enlargement - inf. lateral ventricle maintains its expected proportions without signs of enlargement For the cerebral cortex: - mild atrophy of the left frontal lobe; normal-to-mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: opercular inf. frontal gyrus (mild atrophy both left/right), posterior orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), supplementary motor cortex (mild-to-moderate atrophy on the left and normal on the right), gyrus rectus (mild atrophy on the left and normal on the right) and triangular inf. frontal gyrus (mild atrophy on the left and normal on the right) - no clear atrophic alterations are visible in the temporal lobe - no clear atrophic alterations are visible in the occipital lobe - no appreciable degenerative or atrophic changes observed in the insular cortex - parietal lobe appears preserved, with no observable tissue loss - limbic cortex maintains a normal appearance with no observable atrophic features
PNFA
FTLD_203355715_01515_MR_Sagittal_MP-Rage_br_raw_20230206143046077_I10181202
On a T1-weighted brain MRI we observed: For the cerebral cortex: - the parietal lobe shows no notable changes suggestive of atrophy - the temporal lobe shows no notable changes suggestive of atrophy - limbic cortex maintains a normal appearance with no observable atrophic features - mild bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: precentral gyrus (mild atrophy both left/right), sup. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), sup. frontal gyrus medial segment (normal-to-mild atrophy on the left and mild atrophy on the right), triangular inf. frontal gyrus (mild atrophy on the left and normal on the right), gyrus rectus (mild atrophy on the left and normal on the right) and medial orbital gyrus (normal on the left and mild atrophy on the right) - no clear atrophic alterations are visible in the occipital lobe - insular cortex appears preserved, with no observable tissue loss For the ventricles: - mild enlargement of the external csf - mild enlargement of the 3rd ventricle - mild enlargement of the left inf. lateral ventricle; normal-to-mild enlargement of the right inf. lateral ventricle - no findings suggestive of enlargement are seen in the 4th ventricle - moderate bilateral enlargement of the lateral ventricle For the subcortical structures: - mild-to-moderate atrophy of the left thalamus and mild atrophy of the right thalamus - mild atrophy of the left putamen; normal-to-mild atrophy of the right putamen - the left hippocampus volume is borderline low - the pallidum shows no notable changes suggestive of atrophy - accumbens appears preserved, with no observable tissue loss - ventral dc appears preserved, with no observable tissue loss - amygdala maintains a normal appearance with no observable atrophic features - mild bilateral atrophy of the caudate - no clear atrophic alterations are visible in the basal forebrain
PNFA
FTLD_203735377_03773_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10451145
On a T1-weighted brain MRI we observed: For the cerebral cortex: - severe atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (severe atrophy on the left and mild-to-moderate atrophy on the right), inf. temporal gyrus (moderate-to-severe atrophy on the left), fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and middle temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) - no findings suggestive of atrophy are seen in the insular cortex - no findings suggestive of atrophy are seen in the parietal lobe - no appreciable degenerative or atrophic changes observed in the limbic cortex - occipital lobe appears within normal limits without apparent atrophy - frontal lobe demonstrates a healthy morphology without signs of atrophy For the ventricles: - mild-to-moderate bilateral enlargement of the lateral ventricle - no findings suggestive of enlargement are seen in the 3rd ventricle - 4th ventricle maintains its expected proportions without signs of enlargement - severe enlargement of the left inf. lateral ventricle and mild-to-moderate enlargement of the right inf. lateral ventricle - external csf appears to be of normal dimensions, with no observable increase in size For the subcortical structures: - basal forebrain demonstrates a healthy morphology without signs of atrophy - no clear atrophic alterations are visible in the thalamus - mild-to-moderate atrophy of the left hippocampus - the left hippocampus volume is borderline low - severe atrophy of the left amygdala and mild-to-moderate atrophy of the right amygdala - no evident atrophy or tissue thinning seen in the pallidum - caudate appears within normal limits without apparent atrophy - mild-to-moderate atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens - no clear atrophic alterations are visible in the ventral dc - putamen maintains a normal appearance with no observable atrophic features
SV
ADNI_128_S_1043_MR_MT1__GradWarp__N3m_Br_20140814091209585_S225558_I439322
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no observable atrophic changes in the frontal lobe - no clear atrophic alterations are visible in the parietal lobe - insular cortex appears preserved, with no observable tissue loss - no clear atrophic alterations are visible in the occipital lobe - mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: middle cingulate gyrus (mild-to-moderate atrophy on the left) - no observable atrophic changes in the temporal lobe For the ventricles: - the 4th ventricle shows no notable changes suggestive of enlargement - moderate-to-severe enlargement of the left inf. lateral ventricle and mild-to-moderate enlargement of the right inf. lateral ventricle - external csf appears to be of normal dimensions, with no observable increase in size - moderate-to-severe enlargement of the left lateral ventricle and mild-to-moderate enlargement of the right lateral ventricle - mild enlargement of the 3rd ventricle For the subcortical structures: - caudate appears preserved, with no observable tissue loss - mild bilateral atrophy of the pallidum - moderate atrophy of the left hippocampus - mild atrophy of the right hippocampus - putamen appears within normal limits without apparent atrophy - accumbens appears within normal limits without apparent atrophy - the basal forebrain shows no notable changes suggestive of atrophy - mild-to-moderate atrophy of the left thalamus; normal-to-mild atrophy of the right thalamus - no appreciable degenerative or atrophic changes observed in the ventral dc - mild atrophy of the right amygdala; the left amygdala is normal
AD
FTLD_203030524_03423_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450704
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no findings suggestive of atrophy are seen in the parietal lobe - limbic cortex appears preserved, with no observable tissue loss - mild-to-moderate atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: opercular inf. frontal gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), triangular inf. frontal gyrus (mild-to-moderate atrophy both left/right), orbital inf. frontal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), medial frontal cortex (mild atrophy on the left and normal-to-mild atrophy on the right), posterior orbital gyrus (mild-to-moderate atrophy on the left and normal on the right), gyrus rectus (mild atrophy on the left and normal on the right) and middle frontal gyrus (mild atrophy on the left) - mild-to-moderate atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right) and frontal operculum (mild-to-moderate atrophy on the left and mild atrophy on the right) - moderate atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: temporal pole (moderate atrophy on the left and normal-to-mild atrophy on the right), fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and planum temporale (mild atrophy on the left) - no clear atrophic alterations are visible in the occipital lobe For the ventricles: - mild enlargement of the left lateral ventricle; the right lateral ventricle is normal - no findings suggestive of enlargement are seen in the 4th ventricle - mild-to-moderate enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal - mild enlargement of the external csf - mild enlargement of the 3rd ventricle For the subcortical structures: - ventral dc maintains a normal appearance with no observable atrophic features - moderate atrophy of the left caudate and mild atrophy of the right caudate - moderate atrophy of the left accumbens and mild atrophy of the right accumbens - no appreciable degenerative or atrophic changes observed in the basal forebrain - no evident atrophy or tissue thinning seen in the hippocampus - thalamus appears within normal limits without apparent atrophy - mild-to-moderate atrophy of the left amygdala; the right amygdala is normal - moderate atrophy of the left putamen and mild-to-moderate atrophy of the right putamen - mild-to-moderate atrophy of the left pallidum and mild atrophy of the right pallidum
PNFA
FTLD_203447418_03814_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10451166
On a T1-weighted brain MRI we observed: For the cerebral cortex: - limbic cortex demonstrates a healthy morphology without signs of atrophy - no clear atrophic alterations are visible in the parietal lobe - mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: parietal operculum (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), posterior insula (mild atrophy on the left) and central operculum (mild atrophy on the left and normal on the right) - occipital lobe appears preserved, with no observable tissue loss - the frontal lobe shows no notable changes suggestive of atrophy - severe atrophy of the left temporal lobe and moderate-to-severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), middle temporal gyrus (moderate-to-severe atrophy on the left and mild atrophy on the right), inf. temporal gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), fusiform gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), planum temporale (mild atrophy on the left and mild-to-moderate atrophy on the right) and sup. temporal gyrus (mild atrophy on the left and normal on the right) For the ventricles: - severe enlargement of the left inf. lateral ventricle and moderate-to-severe enlargement of the right inf. lateral ventricle - no evident size increase noted in the external csf - mild bilateral enlargement of the lateral ventricle - 4th ventricle appears to be of normal dimensions, with no observable increase in size - no appreciable enlargement noted in the 3rd ventricle For the subcortical structures: - mild atrophy of the left putamen; the right putamen is normal - moderate atrophy of the left hippocampus - mild atrophy of the right hippocampus - no clear atrophic alterations are visible in the basal forebrain - no observable atrophic changes in the pallidum - severe atrophy of the left amygdala and mild-to-moderate atrophy of the right amygdala - thalamus appears preserved, with no observable tissue loss - mild atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens - ventral dc appears preserved, with no observable tissue loss - no evident atrophy or tissue thinning seen in the caudate
SV
FTLD_203207681_03180_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178283
On a T1-weighted brain MRI we observed: For the cerebral cortex: - moderate bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: central operculum (moderate atrophy on the left and mild-to-moderate atrophy on the right), parietal operculum (mild atrophy on the left and moderate atrophy on the right) and anterior insula (mild atrophy both left/right) - mild atrophy of the right temporal lobe; normal-to-mild atrophy of the left temporal lobe; focal volume loss observed in the following subregions: planum temporale (mild atrophy on the left and mild-to-moderate atrophy on the right) and sup. temporal gyrus (normal on the left and mild-to-moderate atrophy on the right) - no observable atrophic changes in the occipital lobe - mild atrophy of the left parietal lobe; the right parietal lobe is normal; focal volume loss observed in the following subregions: precuneus (mild atrophy both left/right), angular gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), postcentral gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and supramarginal gyrus (mild atrophy on the left) - mild atrophy of the right limbic cortex; normal-to-mild atrophy of the left limbic cortex; focal volume loss observed in the following subregions: parahippocampal gyrus (mild atrophy both left/right), posterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and anterior cingulate gyrus (normal on the left and mild atrophy on the right) - no appreciable degenerative or atrophic changes observed in the frontal lobe For the ventricles: - moderate enlargement of the left inf. lateral ventricle; normal-to-mild enlargement of the right inf. lateral ventricle - no clear enlargement or abnormal growth seen in the external csf - 4th ventricle appears within normal size limits with no apparent enlargement - 3rd ventricle maintains its expected proportions without signs of enlargement - moderate-to-severe enlargement of the left lateral ventricle and moderate enlargement of the right lateral ventricle For the subcortical structures: - no observable atrophic changes in the ventral dc - hippocampus appears preserved, with no observable tissue loss - caudate appears preserved, with no observable tissue loss - putamen appears within normal limits without apparent atrophy - no clear atrophic alterations are visible in the basal forebrain - thalamus demonstrates a healthy morphology without signs of atrophy - mild bilateral atrophy of the accumbens - mild atrophy of the left amygdala; normal-to-mild atrophy of the right amygdala - no appreciable degenerative or atrophic changes observed in the pallidum
BV