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Emergence of ciprofloxacin resistance with high levels of MIC values (up to 32 micro g/ml) in India is alarming. Double and triple mutations in gyrA alone or together in gyrA and parC could be responsible for such a high resistance. | research_paper |
This conceptual framework provides a step-wise roadmap to guide health-care systems and organizations in the provision PCC across various health-care sectors. | literature_review |
Foreign Direct Investment (FDI) is an important field, yet only a few comprehensive reviews available on its current development. There are several meta-analysis studies and systematic literature reviews. However, none has summarized the findings in a unity. This study examines 31 meta-analysis articles and systematic ... | literature_review |
A vital step in the development of an equal partnership for minorities in the academic, social, and economic life of the United States involves moving away from assumptions of the linear model of cultural acquisition. In this article we review the literature on the psychological impact of being bicultural. Assimilation... | literature_review |
OBJECTIVE: To identify environmental features of multi-family housing (MFH) and their surrounding neighborhoods that influence residents' physical activity (PA). DATA SOURCE: Articles published between January 2000 and September 2023 were identified from major social science, medical, health, behavioral science, and ur... | literature_review |
In this paper, two types of reconflgurable Dielectric Resonator Antennas (DRAs) are presented. The designs are based on rotating a Dielectric Resonator (DR), placed on the patch of the antenna, using a DC stepper motor connected to the DR to reconflgure the notch frequency, in the flrst, and the resonance frequency in ... | research_paper |
This work consists of a scoping review to answer the question: What are the attributes that makeup care management in different settings where nurses work? The review will be based on the Joanna Briggs Institute (JBI) recommendations, to map national and international scientific evidence on the attributes that shape ca... | literature_review |
Large-genome eukaryotes use heritable cytosine methylation to silence promoters, especially those associated with transposons and imprinted genes. Cytosine methylation does not reinforce or replace ancestral gene regulation pathways but instead endows methylated genomes with the ability to repress specific promoters in... | literature_review |
Exhausts of airship fabric bag in the stratosphere such as hydrogen which can be used for fuels by using catalytic combustion method.This can save the extra fuels used in the power system.Pd/γ-Al2O3 catalyst was prepared in this work by impregnation method and the H2 catalytic combustion reaction kinetic was investigat... | research_paper |
ABSTRACT Moraxella catarrhalis is subjected to oxidative stress from both internal and environmental sources. A previous study (C. D. Pericone, K. Overweg, P. W. Hermans, and J. N. Weiser, Infect. Immun. 68 :3990-3997, 2000) indicated that a wild-type strain of M. catarrhalis was very resistant to killing by exogenous ... | research_paper |
ABSTRACT The membrane-proximal external region (MPER) of human immunodeficiency virus type 1 (HIV-1) gp41 bears the epitopes of two broadly neutralizing antibodies (Abs), 2F5 and 4E10, making it a target for vaccine design. A third Ab, Fab Z13, had previously been mapped to an epitope that overlaps those of 2F5 and 4E1... | research_paper |
Spinal muscular atrophy is an autosomal recessive neuromuscular disease mainly caused by homozygous deletion of SMN1. The 2-copy SMN1 allele may present in the families of SMA patients with homozygous deletion of SMN1, one of whose parents has two SMN1 copies. In such families, individuals having two SMN1 copies still ... | literature_review |
Interference alignment (IA) can effectively eliminate the interference among users in cognitive radio (CR) networks. Nevertheless, to further increase the transmission rate of the primary user (PU) and guarantee its priority, we propose an optimal transceiver design (OTD) scheme for IA-based CR networks in this letter.... | research_paper |
The recent World Health Organization (WHO) agreement on the standardized classification of overweight and obese, based on body mass index (BMI), allows a comparable analysis of prevalence rates worldwide for the first time. In Asia, however, there is a demand for a more limited range for normal BMIs (i.e., 18.5 to 22.9... | literature_review |
SLE was associated with a significant increase in maternal pregnancy complications and in fetal and neonatal morbidity and mortality as compared to the control population. However, our population-based study found significantly fewer adverse outcomes than were previously reported. This may represent a more accurate cli... | research_paper |
Glia constitute roughly half of the cells of the central nervous system (CNS) but were long-considered to be static bystanders to its formation and function. Here we provide an overview of how the diverse and dynamic functions of glial cells orchestrate essentially all aspects of nervous system formation and function. ... | literature_review |
The experience of integrative TCM/WM in the treatment of SARS is encouraging. The use of TCM as an adjunctive therapy in the treatment of SARS should be further investigated. | literature_review |
Abstract Recombinant murine GM‐CSF produced in Escherichia coli was purified to homogeneity and tested in parallel with purified native GM‐CSF. Both recombinant and native GM‐CSF stimulated granulocyte and/or macrophage colony formation by adult and fetalmouse progenitor cells, and with adult marrow cells the specific ... | research_paper |
The quest for novel therapies to prevent bacterial infections and blood clots (thrombosis) is of utmost importance in biomedical research due to the exponential growth in the cases of thrombosis and blood infections and the emergence of multi-drug-resistant strains of bacteria. Endogenous nitric oxide (NO) is a cellula... | research_paper |
This paper aims to discuss various aspects of the use of reference genes in qPCR technique used in the thousands of present studies. Most frequently, these are housekeeping genes and they must meet several criteria so that they can lay claim to the name. Lots of papers report that in different conditions, for different... | literature_review |
ABSTRACT Antiretroviral therapy (ART) is successful in the suppression of HIV but cannot target and eradicate the latent proviral reservoir. The location of retroviral integration into the human genome is thought to play a role in the clonal expansion of infected cells and HIV persistence. We developed a high-throughpu... | research_paper |
In recent years, immunotherapy represented by immune checkpoint inhibitors (ICIs) has led to unprecedented breakthroughs in cancer treatment. However, the fact that many tumors respond poorly or even not to ICIs, partly caused by the absence of tumor-infiltrating lymphocytes (TILs), significantly limits the application... | literature_review |
Chronic otitis media (COM) often leads to ossicular chain damage, necessitating ossiculoplasty for hearing restoration. Various prosthetic materials are available, including autologous grafts and synthetic materials like titanium, hydroxyapatite, and teflon. However, the comparative efficacy of these materials in ossic... | literature_review |
The most common nosocomial pathogens may well survive or persist on surfaces for months and can thereby be a continuous source of transmission if no regular preventive surface disinfection is performed. | literature_review |
CD24 is a highly glycosylated glycophosphatidylinositol (GPI)-anchored protein that is expressed in many types of differentiating cells and some mature cells of the immune system as well as the central nervous system. CD24 has been extensively used as a biomarker for developing B cells as its expression levels change o... | research_paper |
Abstract Tick control represent a great challenge to animal health. The objective of this study was to evaluate the efficacy of acaricidal compounds against Rhipicephalus microplus from dairy cattle systems in Paraná State, Brazil. Six farms (PR1-PR6) were selected, where anti-tick products were applied at fixed interv... | research_paper |
Large Language Models (LLMs) have shown promise in natural language processing tasks, with the potential to automate systematic reviews. This study evaluates the performance of three state-of-the-art LLMs in conducting systematic review tasks. We assessed GPT-4, Claude-3, and Mistral 8x7B across four systematic review ... | literature_review |
Summary CD20 is an effective target for therapeutic B‐cell depletion with monoclonal antibodies. One proposed mechanism of action is direct cytotoxicity mediated via tyrosine kinase‐dependent signalling pathways activated upon CD20 cross‐linking. The association of CD20 with membrane microdomains known as lipid rafts, ... | research_paper |
The use of extracellular vesicles, specifically exosomes, as carriers of biomarkers in extracellular spaces has been well demonstrated. Despite their promising potential, the use of exosomes in the clinical setting is restricted due to the lack of standardization in exosome isolation and analysis methods. The purpose o... | literature_review |
We investigate the coherent dynamics of a non-interacting Bose-Einstein\ncondensate in a system consisting of two bosonic reservoirs coupled via a\nspatially localized mode. We describe this system by a two-terminal\nFano-Anderson model and investigate analytically the time evolution of\nobservables such as the bosonic... | research_paper |
Measuring the impedance frequency response of systems by means of frequency sweep electrical impedance spectroscopy (EIS) takes time. An alternative based on broadband signals enables the user to acquire simultaneous impedance response data collection. This is directly reflected in a short measuring time compared to th... | research_paper |
LAY SUMMARY Partners of military members and Veterans face not only the usual challenges that most families encounter but also additional difficulties due to their partners’ dangerous deployments and frequent moves. This study reviewed 13 articles to evaluate non-pharmacological treatments designed to improve the menta... | literature_review |
NF-kappaB (nuclear factor-kappaB) is a collective name for inducible dimeric transcription factors composed of members of the Rel family of DNA-binding proteins that recognize a common sequence motif. NF-kappaB is found in essentially all cell types and is involved in activation of an exceptionally large number of gene... | literature_review |
The following paper focuses on the incompleteness arising from model misspecification combined with trading restrictions. While asset price dynamics are assumed to be continuous time processes, the hedging of contingent claims occurs in discrete time. The trading strategies under consideration are understood to be self... | research_paper |
ABSTRACT Different human immunodeficiency virus (HIV)/simian immunodeficiency virus (SIV) vaccine vectors expressing the same viral antigens can elicit disparate T-cell responses. Within this spectrum, replicating variable vaccines, like SIVmac239Δnef, appear to generate particularly efficacious CD8 + T-cell responses.... | research_paper |
be truly designated “dialogues, ” I will raise specific and critical questions about the putative circadian rhythm disturbances in depression, provide a model within which to understand them, and summarize the present status and application of chronobiological therapies. This short overview will not go into detail of t... | literature_review |
Although there was some individual variation, at a mean of 13 months following surgery, there was no significant change in the average junctional intervertebral motion. If fusion is going to affect adjacent motion, it appears that this does not consistently occur in the first 1 to 2 years following surgery. Additionall... | research_paper |
This paper addresses the problem of scheduling n independent jobs processed non-preemptively on m identical parallel machines with the objective of minimising makespan. We consider four popular construction algorithms, LPT, MULTIFIT, COMBINE, and LISTFIT from the literature, which are used for minimising makespan for s... | literature_review |
DNA methylation is a major epigenetic modification of the genome that regulates crucial aspects of its function. Genomic methylation patterns in somatic differentiated cells are generally stable and heritable. However, in mammals there are at least two developmental periods-in germ cells and in preimplantation embryos-... | literature_review |
Abstract Chitin and chitosan are considerably versatile and promising biomaterials. The deacetylated chitin derivative chitosan is a useful and interesting bioactive polymer. Despite its biodegradability, it has many reactive amino side groups, which offer possibilities of chemical modifications, formation of a large v... | literature_review |
An ectopic ureterocele is a rare congenital anomaly often managed surgically due to risks of urinary tract infections (UTIs), hydronephrosis, and renal impairment. Yet there is no consensus on selecting surgical or conservative observation therapy. A girl was diagnosed antenatally with a left ectopic ureterocele. Postn... | literature_review |
ABSTRACT Human immunodeficiency virus type 1 (HIV-1) entry into target cells is mediated by the virus envelope binding to CD4 and the conformationally altered envelope subsequently binding to one of two chemokine receptors. HIV-1 envelope glycoprotein (gp120) has five variable loops, of which three (V1/V2 and V3) influ... | research_paper |
Abstract Rheumatoid arthritis is characterized by synovial joint infiltration of activated CD4+ T cells and MHC class II+ APC, and is linked to specific HLA-DR alleles. Candidate autoantigens in synovial fluid and cartilage include type II collagen (CII) and cartilage gp39 (HCgp39). Using preparations of native Ag and ... | research_paper |
In this paper a novel model of the packed U-cell (PUC) inverter is derived considering the concept of single-phase multilevel converters. Based on the proposed model, a voltage balancing controller is designed to apply on the 7-level PUC inverter. The applied controller is in charge of fixing the capacitor voltage in P... | research_paper |
Abstract We have attempted to purify envelope (Env) glycoproteins of human immunodeficiency virus (HIV) from the culture supernatants of CHO‐Sec cells that secreted truncated 140‐kDa precursor and mature 120‐kDa Env glycoproteins. The concentrated culture supernatants were applied to a column coupled with cibacron blue... | research_paper |
The lymphocyte function of anergic surgical patients who are at increased risk for sepsis and mortality was studied. In vitro lymphocyte responses appear to be normal in most instances, in that over 80% of patients showed a normal response in a standardized mixed leucocyte culture reaction. Similarly, 56% of the lympho... | research_paper |
International variations in cancer rates have been attributed, at least in part, to differences in dietary intake. Recently, it has been suggested that consumption of soyfoods may contribute to the relatively low rates of breast, colon, and prostate cancers in countries such as China and Japan. Soybeans contain a numbe... | literature_review |
Although a variety of microorganisms have caused infective endocarditis, Nocardia species have rarely been reported as a causative agent of the disease. We describe a case of nocardial endocarditis, occurring to a 22-year-old Japanese woman during long-term corticosteroid therapy for adult-onset Still's disease and dia... | literature_review |
IMPORTANCE: The recent advances in the field of machine learning have raised expectations that computer-aided diagnosis will become the standard for the diagnosis of melanoma. OBJECTIVE: To critically review the current literature and compare the diagnostic accuracy of computer-aided diagnosis with that of human expert... | literature_review |
Abstract Pool boiling heat transfer offers high-performance cooling opportunities for thermal problems of electronics limited with high heat fluxes. Therefore, many researchers have been extensively studying over the last six decades. This paper presents a critical literature review of various parametric effects on poo... | literature_review |
The long-term effectiveness of antibody responses relies on the development of humoral immune memory. Humoral immunity is maintained by long-lived plasma cells that secrete antigen-specific antibodies, and memory B cells that rapidly respond to antigen re-exposure by generating new plasma cells and memory B cells. Deve... | research_paper |
In ligand design for asymmetric catalysis, the usual norm is to derive the face shielding elements from a chiral source. New ligands in which the face shielding is determined by fluxional groups are introduced. Their design, modular synthesis, and experiments to demonstrate the significance of the fluxional groups are ... | research_paper |
International migration has been consistently rising in modern times, and understanding what factors are associated with the successful inclusion of migrants is urgent. This meta-analysis helps pinpoint such factors by identifying the most robust social and contextual correlates of successful migrant adaptation to livi... | literature_review |
Summary The principal findings reported in this communication are: 1) the minimum antigen dose necessary to initiate a near maximum antibody response is about 105 times greater for irradiated than for unirradiated spleen cells, and 2) the compartment of immunologically committed progenitor cells (PC2) lacks the potenti... | research_paper |
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTElectrical properties of solid oxide electrolytesT. H. Etsell and Spyridon N. FlengasCite this: Chem. Rev. 1970, 70, 3, 339–376Publication Date (Print):June 1, 1970Publication History Published online1 May 2002Published inissue 1 June 1970https://pubs.acs.org/doi/10.1021/cr60... | literature_review |
Antimicrobial resistance is a global public health crisis. Effective antimicrobial stewardship requires an understanding of the factors and context that contribute to inappropriate use of antimicrobials. The goal of this qualitative systematic review was to synthesize themes across levels of the social ecological frame... | literature_review |
Abstract Small ubiquitin-like modifier (SUMO) is a member of a ubiquitin-like protein superfamily. SUMOylation is a reversible posttranslational modification that has been implicated in the regulation of various cellular processes including inflammatory responses and expression of type 1 interferons (IFN1). In this rep... | research_paper |
Recent studies have revealed that Foxp3(+)CD25(+)CD4(+) regulatory T cells (Tregs), which are physiologically engaged in the maintenance of immunological self-tolerance, play critical roles for the control of antitumor immune responses. For example, a large number of Foxp3(+)Tregs infiltrate into tumors, and systemic r... | literature_review |
Abstract A s.c. route of immunization was developed in non-human primates, which targets the genitourinary-rectal associated lymphoid tissue. A vaccine consisting of rSIV gag p27, expressed as hybrid Ty virus-like particles (p27: Ty-VLP) was administered in the proximity of the internal iliac lymph nodes. Secretory IgA... | research_paper |
The role of intraoperative computer-assisted modalities for periacetabular osteotomy (PAO), as well as the perioperative and post-operative outcomes for these techniques, remains poorly defined. The purpose of this systematic review was to evaluate the techniques and outcomes of intraoperative computer-assisted modalit... | literature_review |
Wear and tear from tyres significantly contributes to the flow of (micro-)plastics into the environment. This paper compiles the fragmented knowledge on tyre wear and tear characteristics, amounts of particles emitted, pathways in the environment, and the possible effects on humans. The estimated per capita emission ra... | literature_review |
INTRODUCTION: Guidelines recommend clozapine for treatment-resistant schizophrenia. However, meta-analysis of aggregate data (AD) did not demonstrate higher efficacy of clozapine compared with other second-generation antipsychotics but found substantial heterogeneity between trials and variation between participants in... | literature_review |
The Hippo pathway was initially discovered in Drosophila melanogaster as a key regulator of tissue growth. It is an evolutionarily conserved signaling cascade regulating numerous biological processes, including cell growth and fate decision, organ size ...Read More | literature_review |
Noroviruses are now recognized as the leading cause of epidemics of gastroenteritis and an important cause of sporadic gastroenteritis among both children and adults. In the United States, more than 90% of the outbreaks of gastroenteritis for which the cause could not previously be identified can now be attributed to t... | literature_review |
A single-protein or -peptide vaccine is not sufficient to arouse immune responses in cancer therapy. A whole-tumor-cell vaccine with complete cancer cell antigens and all conformations elicits robust immune responses and is a promising method for the treatment of advanced malignant tumors. In this study, we used 5-azac... | research_paper |
ABSTRACT: A systematic review involves the identification, evaluation, and synthesis of the best-available evidence to provide an answer to a specific question. The "best-available evidence" is, in many cases, a peer-reviewed scientific article published in an academic journal that details the conduct and results of a ... | literature_review |
ABSTRACT The human immunodeficiency virus type 1 (HIV-1) gp120 exterior envelope glycoprotein is conformationally flexible. Upon binding to the host cell receptor CD4, gp120 assumes a conformation that is recognized by the second receptor, CCR5 and/or CXCR4, and by the CD4-induced (CD4i) antibodies. Guided by the X-ray... | research_paper |
Inflammatory myofibroblastic tumor (IMT) is a benign neoplasm of intermediate biologic potential. It rarely occurs in the larynx, and it has not been previously reported in the epiglottis. We treated a 66-year-old woman who presented with progressive dysphonia and a mass on her suprahyoid epiglottis. The tumor was comp... | literature_review |
HIV-1 latency is a major obstacle to HIV-1 eradication. Coinfection with HTLV-1 has been associated with faster progression to AIDS. HTLV-1 encodes the transactivator Tax which can activate both HTLV-1 and HIV-1 transcription. Here, we demonstrate that Tax activates HIV transcription in latent CD4<sup>+</sup> T cells. ... | research_paper |
Cyperus rotundus L. has been widely used in the treatment and prevention of numerous diseases in traditional systems of medicine around the world, such as nervous, gastrointestinal systems diseases and inflammation. In traditional Chinese medicine (TCM), its rhizomes are frequently used to treat liver disease, stomach ... | literature_review |
Few data are available on the seroprevalence of antibodies to Bartonella henselae among children. We retrospectively evaluated the presence of immunoglobulin G and M class antibodies to B. henselae in 508 children living in central Italy who were apparently free of any features suggesting B. henselae infection. We foun... | research_paper |
We have characterized 43 nef sequences from subtype C HIV-1-infected South Africans and compared deduced amino acid sequences with other subtypes to identify areas of conservation. Our Nef amino acid sequences were aligned with a consensus subtype B, HXB2 reference strain and a consensus subtype C sequence. All were fo... | research_paper |
Adolescence is a time of considerable development at the level of behaviour, cognition and the brain. This article reviews histological and brain imaging studies that have demonstrated specific changes in neural architecture during puberty and adolescence, outlining trajectories of grey and white matter development. Th... | literature_review |
OBJECTIVE: The aim of the present study was to review original clinical studies published in indexed databases, which assessed the role of oral yeasts in the etiopathogenesis of peri-implantitis. DESIGN: The focused question was "Do oral yeasts play a role in the etiopathogenesis of peri-implantitis?". Indexed database... | literature_review |
Medical education is often considered as very stressful. It often causes declines in subjective well-being in clinical medical students (CMS), because of the heavy workload, fear of failing exams for those students, especially for them with English Learning Difficulties (ELD). Research indicates that CMS with ELD often... | literature_review |
Abstract The classical pathway of complement (CP) can mediate C3 opsonization of Ags responsible for the costimulation and activation of cognate B lymphocytes. In this manner, the complement system acts as a bridge between the innate and adaptive immune systems critical for establishing a humoral response. However, abe... | research_paper |
Abstract Objective Due to high rates of irrational use of medicines and low rates of medication adherence among older Iranian patients, this study aimed to explore the determinants of medication adherence in the elderly. Methods This qualitative study was conducted in 2019 via 20 semi‐structured interviews with a purpo... | research_paper |
Tolerance of plants to abiotic stressors such as drought and salinity is triggered by complex multicomponent signaling pathways to restore cellular homeostasis and promote survival. Major plant transcription factor families such as bZIP, NAC, AP2/ERF, and MYB orchestrate regulatory networks underlying abiotic stress to... | literature_review |
ABSTRACT— Five autopsy cases of peliosis hepatis occurring as a late complication of thorotrast (ThO 2 ) liver disease are described. The liver contained many blood‐filled cystic spaces of various sizes. Marked sinusoidal dilatation, disruption of cell cords and reticulin fiber framework, and cystic dilatation of sinus... | research_paper |
Abstract Bovine respiratory tract disease is a multi-factorial disease complex involving several viruses and bacteria. Viruses that play prominent roles in causing the bovine respiratory disease complex include bovine herpesvirus-1, bovine respiratory syncytial virus, bovine viral diarrhea virus and parinfluenza-3 viru... | research_paper |
A. Search strategy for Ovid MEDLINE Epub Ahead of Print, In-Process & Other Non-Indexed Citations, Ovid MEDLINE Daily and Ovid MEDLINE. Data S2 B. Search strategy for EMBASE. Data S2 C. Search strategy for Scopus. Data S3 Exclusion of studies that had the same patient cohort. Data S4 Data of the included cohort stu... | literature_review |
Aspergillus species are globally ubiquitous saprophytes found in a variety of ecological niches. Almost 200 species of aspergilli have been identified, less than 20 of which are known to cause human disease. Among them, Aspergillus fumigatus is the most prevalent and is largely responsible for the increased incidence o... | literature_review |
Over the 10-year period, a stepwise increase in the consumption of broad-spectrum antibiotics and antibiotics against MDR pathogens was observed at a tertiary care hospital in Korea. Conversely, during the same period, nonbroad-spectrum antibiotic consumption showed a significant decreasing trend. | research_paper |
The CD95 (APO-1/Fas) receptor has attracted great interest in recent years because it transduces an apoptotic signal in a variety of different tissues. CD95 belongs to the NGF/TNF-receptor superfamily, members of which need to be trimerized by specific protein ligands in order to generate a signal. This review focuses ... | research_paper |
Article1 May 1935ARTERIOSCLEROSIS IN DIABETESI. RELATIONSHIP BETWEEN PLASMA CHOLESTEROL AND ARTERIOSCLEROSIS. II. EFFECTS OF THE HIGH CARBOHYDRATE-LOW CALORIE DIET*I. M. RABINOWITCH, F.A.C.P.I. M. RABINOWITCH, F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-8-11-1436 SectionsAboutPD... | research_paper |
Because administration of Tat protein, the HIV-1 toxin that induces immunosuppression and apoptosis, may be deleterious to the host immune system, a chemically inactivated but nonetheless immunogenic Tat preparation, Tat toxoid, was used to immunize seronegative individuals against Tat. In an open, controlled, phase I ... | research_paper |
The transfer difficulty of patients with hemiparetic stroke decreases when using the lateral transfer method. The lateral transfer method is easy, potentially helping prevent care-related injuries among caregivers. | literature_review |
We describe a strategy to boost anticancer activity and reduce normal cell toxicity of short antimicrobial peptides by adding positive charge amino acids and non-nature bulky amino acid β-naphthylalanine residues to their termini. Among the designed peptides, K4R2-Nal2-S1 displayed better salt resistance and less toxic... | research_paper |
ABSTRACT Gene technology can offer creative solutions to problems of agronomical relevance, which may not be solved by conventional breeding methods. One of the major problems of wheat cultivation is disease caused by a number of fungal pathogens including the wheat powdery mildew fungus Blumeria graminis f.sp. tritici... | research_paper |
Endophenotypes, measurable components unseen by the unaided eye along the pathway between disease and distal genotype, have emerged as an important concept in the study of complex neuropsychiatric diseases. An endophenotype may be neurophysiological, biochemical, endocrinological, neuroanatomical, cognitive, or neurops... | literature_review |
The aims of this study were to identify, assess, and summarise available evidence about the effectiveness of static air mattress overlays to prevent pressure ulcers. The primary outcome was the incidence of pressure ulcers. Secondary outcomes included costs and patient comfort. This study was a systematic review. Six e... | literature_review |
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease accompanied by persistent multiarticular synovitis and cartilage degradation. The present clinical treatments are limited to disease-modifying anti-rheumatic drugs (DMARDs) and aims to relieve pain and control the inflammation of RA. Despite conside... | research_paper |
Posing the right research question is essential for consolidating your ideas from something that has piqued your interest into a focused, clinically relevant and achievable piece of research. This question should lead to results that can impact upon patient benefit by addressing a gap in your field, such as understandi... | research_paper |
Purpose of review Home monitoring is one of the methods of using telemedical technologies aimed to provide care at home and maintain a connection between patients and healthcare providers. The purpose of this review is to describe recent advancements in the use of home monitoring for the care and management of chronic ... | literature_review |
ABSTRACT The 17-kDa antigen of Bartonella henselae has previously been shown to elicit a strong humoral immune response in patients with cat scratch disease (CSD) and to be useful in screening human serum samples for CSD. In this study, PCR amplification of genes homologous to the 17-kDa antigen gene of B. henselae was... | research_paper |
Gynaecomastia is the most common benign breast disorder in men. Among the various causes, testicular malignancies are an uncommon, life-threatening condition requiring prompt diagnosis and treatment. The case of a 28-year-old man is discussed, who presented with a 6-month history of painful bilateral gynaecomastia with... | literature_review |
Abstract The abilities of various macrophage‐activating agents to trigger tumoricidal activity and/or the secretion of prostaglandin E 2 (PGE 2 ), interleukin 6 (IL 6) and transforming growth factor β (TGFβ) in bone marrow‐derived mononuclear phagocytes (BMMΦ) in vitro were comparatively assessed. Induction of tumorici... | research_paper |
The antibiotics that are recommended for treatment of pelvic inflammatory disease (PID) in the outpatient setting are efficacious against Neisseria gonorrhoeae and Chlamydia trachomatis. The susceptibility of non-sexually transmitted pathogens to these agents has not been well studied. The mean inhibitory concentration... | research_paper |
The main objective of this research is to investigate the role of social media campaigns (the type of social media platform, type of message, and message source sender) in raising public health awareness and behavioral change during (COVID-19) as a global pandemic across national selected countries (Poland and Jordan).... | research_paper |
Abstract Mannan-binding lectin (MBL)-associated serine proteases (MASP-1, -2, and -3) are homologous modular proteases that each associate with MBL and L- and H-ficolins, which are oligomeric serum lectins involved in innate immunity. To investigate its physicochemical, interaction, and enzymatic properties, human MASP... | research_paper |
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