databio/diseases-msmarco · Datasets at Hugging Face

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What is Barmah Forest virus disease?	A viral infectious disease that results_in infection located_in joint, has_material_basis_in Barmah Forest virus, which is transmitted_by mosquito bite. The infection has_symptom fever, has_symptom arthralgia, and has_symptom rash.
What is phagocyte bactericidal dysfunction?	A primary immunodeficiency disease where phagocytes have a diminished ability to fight bacterial infection.
What is multiple cutaneous and mucosal venous malformations?	An autosomal dominant disease that is characterized by multiple bluish cutaneous or mucosal venous lesions.
What is syphilis?	A primary bacterial infectious disease that is a sexually transmitted systemic disease, has_material_basis_in Treponema pallidum subsp pallidum, which is transmitted_by sexual contact, transmitted_by blood product transfusion, transmitted_by congenital method from mother to fetus or transmitted_by contact with infectious lesions. If left untreated, produces chancres, rashes, and systemic lesions in a clinical course with three stages continued over many years.
What is open-angle glaucoma?	A glaucoma characterized by optic nerve damage resulting in progressive loss of visual field and increased pressure in the eye due to trabecular blockage.
What is anal condylomata acuminata?	An anogenital venereal wart that results_in infection located_in skin of anus, has_material_basis_in human papillomaviruses (types 6 and 11), which are transmitted_by direct contact with the skin during anal sex with an infected partner. The infection has_symptom anal warts.
What is holoprosencephaly?	A congenital nervous system abnormality characterized by failed or incomplete separation of the forebrain early in gestation; it is accompanied by a spectrum of characteristic craniofacial anomalies.
What is superficial basidiomycota mycosis?	A superficial mycosis that results_in fungal infection of the outermost layer located_in skin and located_in hair shaft, has_material_basis_in Basidiomycota phylum members.
What is Dravet Syndrome?	An epilepsy that is characterized by frequent febrile seizures with onset before 1 year.
What is adult respiratory distress syndrome?	A respiratory failure that results from diffuse injury to the endothelium of the lung (as in sepsis, chest trauma, massive blood transfusion, aspiration of the gastric contents, or pneumonia) and is characterized by pulmonary edema with an abnormally high amount of protein in the edematous fluid and by difficult rapid breathing and hypoxemia.
What is breast angiosarcoma?	An angiosarcoma and sarcoma of breast and vascular neoplasm of breast that is located_in the cells that line the blood vessels within the breast or underarm area.
What is fruit allergy?	A food allergy triggered by a plant fruit product.
What is candidiasis?	An opportunistic mycosis that involves fungal infection of the mouth, throat, skin, scalp, vagina, fingers, nails, bronchi, lungs, heart and brain by Candida species, of which Candida albicans is the most common. Systemic Candida infections are usually confined to severely immunocompromised persons.
What is filarial elephantiasis?	A filariasis that is characterized by the thickening of the skin and underlying tissues, especially in the legs, male genitals and female breasts, caused by thread-like parasitic worms Wuchereria bancrofti, Brugia malayi or Brugia timori, which inhabit the lymphatics. These nematodes are transmitted by mosquitoes. Acute symptoms include fever, lymphadenitis, lymphangitis, funiculitis, and epididymitis. Chronic symptoms include abscesses, hyperkeratosis, polyarthritis, hydroceles, lymphedema, and elephantiasis.
What is Balamuthia mandrillaris infectious disease?	A parasitic protozoa infectious disease that involves infection caused by a free-living ameba Balamuthia mandrillaris resulting in encephalitis and skin lesions in humans and animals.
What is Meckel syndrome?	A ciliopathy that is characterized by renal cystic dysplasia, occipital encephalocele, polydactyly (post axial), hepatic developmental defects, and pulmonary hypoplasia.
What is tic disorder?	A specific developmental disorder that is characterized by the persistent presence of involuntary brief movements or sounds occuring intermittently and unpredictably out of a background of normal motor activity.
What is liver angiosarcoma?	An angiosarcoma and sarcoma of liver and hemangioma of intra-abdominal structure and Ca liver - primary that is located_in the liver.
What is gonorrhea?	A primary bacterial infectious disease that is a sexually transmitted infection, located_in uterus, located_in fallopian tube, located_in urethra, located_in mouth, located_in throat, located_in eye or located_in anus, has_material_basis_in Neisseria gonorrhoeae, which is transmitted_by contact with the penis, vagina, mouth, or anus or transmitted_by congenitally from mother to baby during delivery. The infection has_symptom burning sensation during urination, has_symptom discharge from the penis, has_symptom increased vaginal discharge, or has_symptom vaginal bleeding between periods.
What is phencyclidine abuse?	A substance abuse that involves the recurring use of phencyclidine (PCP) drugs despite negative consequences.
What is spondylocostal dysostosis?	A dysostosis that results_in abnormal development located_in vertebrae or located_in ribs. The bones of the spine do not develop properly, which causes them to be misshapen and abnormally joined together.
What is rectum adenocarcinoma?	A rectum cancer that derives_from epithelial cells of glandular origin.
What is pleomorphic adenoma?	A gastrointestinal benign neoplasm that is a located_in the salivary glands.
What is xanthinuria?	A purine-pyrimidine metabolic disorder characterized by deficiency of xanthine oxidase, resulting in excretion of large amounts of xanthine in the urine and the formation of xanthine stones.
What is early yaws?	A yaws that results in initial papule at the site of entry of bacteria. Without treatment, this is followed by disseminated skin lesions over the body. Bone pain and bone lesions may also occur.
What is borderline leprosy?	A leprosy that results in small numerous red irregularly shaped plaques.
What is aortic disease?	An artery disease that is characterized by degeneration of the cells composing the aortic wall.
What is recurrent hypersomnia?	A sleep disorder that involves recurring bouts of excessive amounts of sleepiness.
What is auditory system cancer?	An organ system cancer located_in the ear and characterized by uncontrolled cellular proliferation of the auditory organs.
What is emphysematous cholecystitis?	Emphysematous cholecystitis is a bacterial infectious disease consisting of an inflammation of the gallbladder characterized by air-filled expansions in interstitial or subcutaneous tissues.
What is amyotrophic lateral sclerosis type 5?	A type of ALS with juvenile onset caused_by homozygous or compound heterozygous mutation in the spatacsin gene (SPG11) on chromosome 15q21.
What is biliary tract cancer?	A gastrointestinal system cancer that results_in malignant growth located_in the gallbladder or located_in the bile duct.
What is toxocariasis?	A parasitic helminthiasis infectious disease that involves zoonotic infection of humans by the larvae of Toxocara canis or Toxocara cati. The larvae invade multiple tissues like liver, heart, lungs, brain, muscle and eyes causing various symptoms including fever, anorexia, weight loss, cough, wheezing, rashes, hepatosplenomegaly, hypereosinophilia and ophthalmologic lesions.
What is adenosquamous gallbladder carcinoma?	A gallbladder carcinoma that derives_from squamous cells and gland-like cells.
What is acute transudative otitis media?	A non-suppurative otitis media and eustachian tube disorder with a sudden onset and a short course.
What is intrinsic asthma?	An asthma that is triggered by factors not related to allergies such as anxiety, stress, exercise, cold air, dry air, hyperventilation, smoke, viruses, chemical irritants, autonomic imbalance, hormonal deficiencies and psychogenic influences. It is characterized by airway obstruction and inflammation that is at least partially reversible with medication. The symptoms include coughing, wheezing, shortness of breath or rapid breathing, and chest tightness.
What is colon adenocarcinoma?	A colon carcinoma that derives_from epithelial cells of glandular origin.
What is gamma heavy chain disease?	A heavy chain disease that results from an overproduction of gamma antibody (IgG).
What is xanthomatosis?	A lipid storage disease that is characterized by the desposition of yellowish cholesterol-rich material in tendons or other body parts.
What is anaerobic pneumonia?	An aspiration pneumonia caused by anaerobic bacteria like Bacteroides fragilis, Peptostreptococcus, anaerobic streptococci, Fusobacterium species (Fusobacterium nucleatum and Fusobacterium necrophoram). Lung abscess and empyema are diagnosed in this disease.
What is lymph node adenoid cystic carcinoma?	A lymph node cancer that is characterized by a distinctive pattern in which abnormal nests or cords of epithelial cells surround and/or infiltrate ducts or glandular structures of the lymph nodes. These structures are typically filled with a mucous-like material or contain abnormal fibrous membranes.
What is synovial sarcoma?	A synovium cancer which develops in the synovial membrane of the joints.
What is relapsing fever?	A primary bacterial infectious disease that results_in infection, has_material_basis_in Borrelia, which is transmitted_by tick or transmitted_by body louse.
What is Reye syndrome?	A syndrome characterized by acute brain damage and liver function problems. It has been associated with aspirin consumption by children with viral illness, although it also occurs in the absence of aspirin use.
What is cerebrovascular disease?	An artery disease that is characterized by dysfunction of the blood vessels supplying the brain.
What is tyrosinemia type I?	A tyrosinemia that has_material_basis_in deficiency of the enzyme fumarylacetoacetate hydrolase resulting in an increase in fumarylacetoacetate which inhibits previous steps in tyrosine degradation leading to an accumulation of tyrosine in the body.
What is strongyloidiasis?	A parasitic helminthiasis infectious disease that involves infection of the intestine, lungs, skin and central nervous system with nematode Strongyloides stercoralis.
What is esophageal disease?	A gastrointestinal system disease that is located_in the esophagus.
What is postherpetic polyneuropathy?	A Varicellovirus infectious disease that results_in pain located_in nerve fiber, has_material_basis_in Human herpesvirus 3, which reactivates after the primary infection, has_symptom severe pain, has_symptom sensitivity to light touch, has_symptom muscle weakness, has_symptom paralysis, and has_symptom itching.
What is myelomeningocele?	A spina bifida characterized by protrusion of the spinal cord through an opening, covered by meningeal membranes.
What is acute laryngopharyngitis?	An upper respiratory tract disease which involves inflammation of both larynx and pharynx.
What is gastrointestinal carcinoma?	A gastrointestinal system cancer that has_material_basis_in epithelial cells.
What is ornithosis?	A primary bacterial infectious disease that results_in systemic infection, has_material_basis_in Chlamydia psittaci, which is transmitted_by inhaling aerosolized dried droppings or transmitted_by contact with infected birds. The infection has_symptom fever, has_symptom headache, has_symptom rash, has_symptom chills, and has_symptom pneumonia.
What is cellular schwannoma?	A neurilemmoma with a predominantly cellular growth but no Verocay bodies.
What is encephalitis?	Encephalitis is a nervous system infectious disease characterized as an acute inflammation of the brain. The usual cause is a viral infection, but bacteria can also cause it. Cases can range from mild to severe. For mild cases, you could have flu-like symptoms. Serious cases can cause severe headache, sudden fever, drowsiness, vomiting, confusion and seizures.
What is extraosseous chondrosarcoma?	A chondrosarcoma that is located_in exclusively soft tissue.
What is Aicardi-Goutieres syndrome?	An autosomal recessive disease that is a genetically heterogeneous encephalopathy characterized in its most severe form by cerebral atrophy, leukodystrophy, intracranial calcifications, chronic cerebrospinal fluid (CSF) lymphocytosis, increased CSF alpha-interferon, and negative serologic investigations for common prenatal infections.
What is selective IgM deficiency disease?	A selective immunoglobulin deficiency disease thatis a dysgammaglobulinemia resulting from decreased levels of immunoglobulin M (IgM) production to roduction of other antibodies.
What is vaginal carcinoma?	A vaginal cancer that has_material_basis_in epithelial cells.
What is recurrent nephroblastoma?	A nephroblastoma that recurs over time.
What is Hallermann-Streiff syndrome?	A syndrome that affects growth, cranial development, hair growth and dental development.
What is Conn's syndrome?	An adrenal admenoma characterized by over production of aldosterone.
What is Histoplasma capsulatum pericarditis?	An American histoplasmosis that results_in inflammation located_in pericardium, has_material_basis_in Histoplasma capsulatum var capsulatum, transmitted_by airborne spores and has_symptom pleural effusions, has_symptom chest pain and has_symptom cough.
What is infantile myofibromatosis?	A connective tissue benign neoplasm that is characterized by the development of benign tumors in the skin, striated muscles, bones, and in exceptional cases, visceral organs.
What is acromelic frontonasal dysostosis?	A dysostosis characterized by cranium bifidum, severe hypertelorism, median cleft lip and palate, nasal bifurcation, brachycephaly, large fontanelle, tibial hemimelia, preaxial polydactyly of the feet and brain malformations.
What is candidal endocarditis?	A candidiasis that results_in inflammation located_in endocardium, has_material_basis_in Candida, which favors previously damaged or prosthetic heart valves. The source is often an intravascular catheter or contaminated equipment used for illicit intravenous drug injection. The illness has_symptom fever, has_symptom murmur, has_symptom congestive heart failure, has_symptom anemia, and has_symptom splenomegaly.
What is verrucous carcinoma?	A squamous cell carcinoma that is a diffuse, papillary, non metastasizing, well differentiated, malignant neoplasm of epidermis or oral epithelium.
What is pertussis?	A commensal bacterial infectious disease that results_in inflammation located_in respiratory tract, has_material_basis_in Bordetella pertussis, or has_material_basis_in Bordetella parapertussis, which produce toxins that paralyze the cilia of the respiratory epithelial cells. The infection is characterized by a prolonged, high-pitched, deeply indrawn breath (whoop).
What is lipid pneumonia?	An aspiration pneumonitis resulting from the aspiration of lipids. It is the result of a foreign body-type reaction to the presence of lipid material within the lung parenchyma. It is caused by inhalation of nasal drops with oil base or cosmetic oil and aspiration of mineral oil when used as a laxative agent.
What is endogenous depression?	A mental depression that is characterized by a dysregulation of the endogenous opioid system and not of the monaminergic system.
What is pulmonary syphilis?	A tertiary syphilis that is caused by the spirochetal bacterium Treponema pallidum subspecies pallidum. It is a sexually transmitted disease although congenital syphilis can also occur. Treponema infection of the lung leads to a fibrous induration spreading from the roots of the lungs. Ulcerations occur in the superficial tissues, while in the deep tissues gummata are formed. Symptoms include dry cough, hemoptysis, hemorrhage, dyspnea, pain in the chest, loss of weight and slight fever.
What is autism spectrum disorder?	A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.
What is trichinosis?	A parasitic helminthiasis infectious disease that involves parasitic infection of animals and humans by Trichinella spiralis, Trichinella nativa or Trichinella britovi . Intestinal invasion causes diarrhea, abdominal pain and vomiting. Larval migration into muscle tissues can cause periorbital and facial edema, conjunctivitis, fever, myalgias, splinter hemorrhages, rashes, and blood eosinophilia. Myocarditis, central nervous system involvement, and pneumonitis can also occur.
What is notochordal cancer?	An embryonal cancer and bone cancer and mesenchymal cell neoplasm that is located_in the notochord.
What is dysgerminoma?	A germ cell cancer that derives_from cells that give rise to egg cells.
What is arthritis?	A bone inflammation disease that involves a response to irritation or injury, characterized by joint pain, swelling, stiffness located_in joint and/or redness located_in skin over the joint.
What is Simpson-Golabi-Behmel syndrome?	An X-linked disease characterized by pre- and postnatal overgrowth and craniofacial, skeletal, cardiac and renal abnormalities.
What is typhoidal tularemia?	A tularemia that results_in bacteremia and has_symptom fever, has_symptom chills, has_symptom myalgia, has_symptom malaise, and has_symptom weight loss.
What is acute hemorrhagic conjunctivitis?	A viral infectious disease that results_in inflammation located in conjunctiva, has_material_basis_in Human coxsackievirus A24 or has_material_basis_in Human enterovirus 70, which are transmitted_by contaminated fomites or transmitted_by contact with contaminated hands. The infection has_symptom vascular dilation, has_symptom eyelid edema, has_symptom photophobia, has_symptom redness of the eyes, has_symptom watering of the eye, has_symptom conjunctival congestion, and has_symptom superficial punctate epithelial keratitis.
What is swine influenza?	An influenza that results_in infection located_in respiratory tract of pigs and humans, has_material_basis_in Influenza C virus, or has_material_basis_in Influenza A virus subtypes (H1N1, H1N2, H3N1, H3N2, and H2N3), which are transmitted_by direct contact with infected pigs. The infection in humans has_symptom fever, has_symptom lethargy, has_symptom lack of appetite, has_symptom coughing, has_symptom runny nose, has_symptom sore throat, has_symptom nausea, has_symptom vomiting, and has_symptom diarrhea.
What is Ancylostoma ceylanicum ancylostomiasis?	An ancylostomiasis that involves parasitic infection of animals and humans by Ancylostoma ceylanicum larvae, which invade percutaneously and migrate to the intestine.
What is glucosephosphate dehydrogenase deficiency?	A carbohydrate metabolic disorder that is characterised by abnormally low levels of glucose-6-phosphate dehydrogenase (abbreviated G6PD or G6PDH).
What is acrodermatitis chronica atrophicans?	An acrodermatitis characterized by a chronically progressive course, leading to widespread atrophy of the skin. It is a clinical manifestation of Lyme borreliosis.
What is pineoblastoma?	A pineal gland neoplasm located_in the brain.
What is hair disease?	An integumentary system disease that is located_in hair.
What is infectious bovine rhinotracheitis?	A Varicellovirus infectious disease that results_in infection in cattle, located_in upper respiratory tract, and located_in genital tract, has_material_basis_in Bovine herpesvirus 1, has_symptom nasal discharge, has_symptom fever, has_symptom abortion, and has_symptom conjunctivitis.
What is lung disease?	A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide.
What is external ear carcinoma?	An external ear cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.
What is toxic shock syndrome?	A commensal bacterial infectious disease that results_in infection, has_material_basis_in Streptococcus pyogenes or has_material_basis_in Staphylococcus aureus , which produce toxins that are absorbed systemically and produce the systemic manifestations. The infection has_symptom fever, has_symptom rash, has_symptom hypotension, has_symptom multiorgan failure, has_symptom desquamation, has_symptom vomiting, has_symptom diarrhea, has_symptom headache, and has_symptom nonfocal neurologic abnormalities.
What is segmental dystonia?	A dystonia that affects two or more adjacent parts of the body.
What is acquired metabolic disease?	A disease of metabolism that has _material_basis_in enzyme deficiency or accumulation of enzymes or toxins which interfere with normal function due to an endocrine organ disease, organ malfunction, inadequate intake, dietary deficiency, or malabsorption.
What is melon allergy?	A fruit allergy triggered by Cucumis melo plant fruit food product.
What is conduct disorder?	A specific developmental disorder marked by a pattern of repetitive behavior wherein the rights of others or social norms are violated.
What is apricot allergy?	A fruit allergy triggered by Prunus armeniaca plant fruit food product.
What is vestibular neuronitis?	A inner ear infectious disease caused by a viral infection which involves inflammation of the vestibular nerve. It usually results as a complication of an upper respiratory infection. This causes sudden and severe vertigo, nausea and vomiting. Auditory symptoms are usually absent.
What is chicken egg allergy?	An egg allergy triggered by Gallus gallus eggs.
What is metachromatic leukodystrophy?	A sphingolipidosis characterized by the accumulation of sulfatides in cells, especially the myelin producing cells of the nervous system.
What is syndromic X-linked intellectual disability?	A syndromic intellectual characterized by an X-linked inheritance pattern.
What is echovirus meningitis?	A coxsackie meningitis that results_in inflammation located_in meningeal cluster, has_material_basis_in Human echovirus 30, or has_material_basis_in Human echovirus 9, which is transmitted_by ingestion of food contaminated with feces, transmitted_by droplet spread of oronasal secretions from infected person, or transmitted_by contaminated fomites. The infection has_symptom fever, has_symptom chills, has_symptom nausea, has_symptom headache, has_symptom photophobia and has_symptom neck stiffness.
What is suppurative otitis media?	A otitis media which involves inflammation of the middle ear with infected effusion containing pus.

What is Barmah Forest virus disease?

A viral infectious disease that results_in infection located_in joint, has_material_basis_in Barmah Forest virus, which is transmitted_by mosquito bite. The infection has_symptom fever, has_symptom arthralgia, and has_symptom rash.

What is phagocyte bactericidal dysfunction?

A primary immunodeficiency disease where phagocytes have a diminished ability to fight bacterial infection.

What is multiple cutaneous and mucosal venous malformations?

An autosomal dominant disease that is characterized by multiple bluish cutaneous or mucosal venous lesions.

What is syphilis?

A primary bacterial infectious disease that is a sexually transmitted systemic disease, has_material_basis_in Treponema pallidum subsp pallidum, which is transmitted_by sexual contact, transmitted_by blood product transfusion, transmitted_by congenital method from mother to fetus or transmitted_by contact with infectious lesions. If left untreated, produces chancres, rashes, and systemic lesions in a clinical course with three stages continued over many years.

What is open-angle glaucoma?

A glaucoma characterized by optic nerve damage resulting in progressive loss of visual field and increased pressure in the eye due to trabecular blockage.

What is anal condylomata acuminata?

An anogenital venereal wart that results_in infection located_in skin of anus, has_material_basis_in human papillomaviruses (types 6 and 11), which are transmitted_by direct contact with the skin during anal sex with an infected partner. The infection has_symptom anal warts.

What is holoprosencephaly?

A congenital nervous system abnormality characterized by failed or incomplete separation of the forebrain early in gestation; it is accompanied by a spectrum of characteristic craniofacial anomalies.

What is superficial basidiomycota mycosis?

A superficial mycosis that results_in fungal infection of the outermost layer located_in skin and located_in hair shaft, has_material_basis_in Basidiomycota phylum members.

What is Dravet Syndrome?

An epilepsy that is characterized by frequent febrile seizures with onset before 1 year.

What is adult respiratory distress syndrome?

A respiratory failure that results from diffuse injury to the endothelium of the lung (as in sepsis, chest trauma, massive blood transfusion, aspiration of the gastric contents, or pneumonia) and is characterized by pulmonary edema with an abnormally high amount of protein in the edematous fluid and by difficult rapid breathing and hypoxemia.

What is breast angiosarcoma?

An angiosarcoma and sarcoma of breast and vascular neoplasm of breast that is located_in the cells that line the blood vessels within the breast or underarm area.

What is fruit allergy?

A food allergy triggered by a plant fruit product.

What is candidiasis?

An opportunistic mycosis that involves fungal infection of the mouth, throat, skin, scalp, vagina, fingers, nails, bronchi, lungs, heart and brain by Candida species, of which Candida albicans is the most common. Systemic Candida infections are usually confined to severely immunocompromised persons.

What is filarial elephantiasis?

A filariasis that is characterized by the thickening of the skin and underlying tissues, especially in the legs, male genitals and female breasts, caused by thread-like parasitic worms Wuchereria bancrofti, Brugia malayi or Brugia timori, which inhabit the lymphatics. These nematodes are transmitted by mosquitoes. Acute symptoms include fever, lymphadenitis, lymphangitis, funiculitis, and epididymitis. Chronic symptoms include abscesses, hyperkeratosis, polyarthritis, hydroceles, lymphedema, and elephantiasis.

What is Balamuthia mandrillaris infectious disease?

A parasitic protozoa infectious disease that involves infection caused by a free-living ameba Balamuthia mandrillaris resulting in encephalitis and skin lesions in humans and animals.

What is Meckel syndrome?

A ciliopathy that is characterized by renal cystic dysplasia, occipital encephalocele, polydactyly (post axial), hepatic developmental defects, and pulmonary hypoplasia.

What is tic disorder?

A specific developmental disorder that is characterized by the persistent presence of involuntary brief movements or sounds occuring intermittently and unpredictably out of a background of normal motor activity.

What is liver angiosarcoma?

An angiosarcoma and sarcoma of liver and hemangioma of intra-abdominal structure and Ca liver - primary that is located_in the liver.

What is gonorrhea?

A primary bacterial infectious disease that is a sexually transmitted infection, located_in uterus, located_in fallopian tube, located_in urethra, located_in mouth, located_in throat, located_in eye or located_in anus, has_material_basis_in Neisseria gonorrhoeae, which is transmitted_by contact with the penis, vagina, mouth, or anus or transmitted_by congenitally from mother to baby during delivery. The infection has_symptom burning sensation during urination, has_symptom discharge from the penis, has_symptom increased vaginal discharge, or has_symptom vaginal bleeding between periods.

What is phencyclidine abuse?

A substance abuse that involves the recurring use of phencyclidine (PCP) drugs despite negative consequences.

What is spondylocostal dysostosis?

A dysostosis that results_in abnormal development located_in vertebrae or located_in ribs. The bones of the spine do not develop properly, which causes them to be misshapen and abnormally joined together.

What is rectum adenocarcinoma?

A rectum cancer that derives_from epithelial cells of glandular origin.

What is pleomorphic adenoma?

A gastrointestinal benign neoplasm that is a located_in the salivary glands.

What is xanthinuria?

A purine-pyrimidine metabolic disorder characterized by deficiency of xanthine oxidase, resulting in excretion of large amounts of xanthine in the urine and the formation of xanthine stones.

What is early yaws?

A yaws that results in initial papule at the site of entry of bacteria. Without treatment, this is followed by disseminated skin lesions over the body. Bone pain and bone lesions may also occur.

What is borderline leprosy?

A leprosy that results in small numerous red irregularly shaped plaques.

What is aortic disease?

An artery disease that is characterized by degeneration of the cells composing the aortic wall.

What is recurrent hypersomnia?

A sleep disorder that involves recurring bouts of excessive amounts of sleepiness.

What is auditory system cancer?

An organ system cancer located_in the ear and characterized by uncontrolled cellular proliferation of the auditory organs.

What is emphysematous cholecystitis?

Emphysematous cholecystitis is a bacterial infectious disease consisting of an inflammation of the gallbladder characterized by air-filled expansions in interstitial or subcutaneous tissues.

What is amyotrophic lateral sclerosis type 5?

A type of ALS with juvenile onset caused_by homozygous or compound heterozygous mutation in the spatacsin gene (SPG11) on chromosome 15q21.

What is biliary tract cancer?

A gastrointestinal system cancer that results_in malignant growth located_in the gallbladder or located_in the bile duct.

What is toxocariasis?

A parasitic helminthiasis infectious disease that involves zoonotic infection of humans by the larvae of Toxocara canis or Toxocara cati. The larvae invade multiple tissues like liver, heart, lungs, brain, muscle and eyes causing various symptoms including fever, anorexia, weight loss, cough, wheezing, rashes, hepatosplenomegaly, hypereosinophilia and ophthalmologic lesions.

What is adenosquamous gallbladder carcinoma?

A gallbladder carcinoma that derives_from squamous cells and gland-like cells.

What is acute transudative otitis media?

A non-suppurative otitis media and eustachian tube disorder with a sudden onset and a short course.

What is intrinsic asthma?

An asthma that is triggered by factors not related to allergies such as anxiety, stress, exercise, cold air, dry air, hyperventilation, smoke, viruses, chemical irritants, autonomic imbalance, hormonal deficiencies and psychogenic influences. It is characterized by airway obstruction and inflammation that is at least partially reversible with medication. The symptoms include coughing, wheezing, shortness of breath or rapid breathing, and chest tightness.

What is colon adenocarcinoma?

A colon carcinoma that derives_from epithelial cells of glandular origin.

What is gamma heavy chain disease?

A heavy chain disease that results from an overproduction of gamma antibody (IgG).

What is xanthomatosis?

A lipid storage disease that is characterized by the desposition of yellowish cholesterol-rich material in tendons or other body parts.

What is anaerobic pneumonia?

An aspiration pneumonia caused by anaerobic bacteria like Bacteroides fragilis, Peptostreptococcus, anaerobic streptococci, Fusobacterium species (Fusobacterium nucleatum and Fusobacterium necrophoram). Lung abscess and empyema are diagnosed in this disease.

What is lymph node adenoid cystic carcinoma?

A lymph node cancer that is characterized by a distinctive pattern in which abnormal nests or cords of epithelial cells surround and/or infiltrate ducts or glandular structures of the lymph nodes. These structures are typically filled with a mucous-like material or contain abnormal fibrous membranes.

What is synovial sarcoma?

A synovium cancer which develops in the synovial membrane of the joints.

What is relapsing fever?

A primary bacterial infectious disease that results_in infection, has_material_basis_in Borrelia, which is transmitted_by tick or transmitted_by body louse.

What is Reye syndrome?

A syndrome characterized by acute brain damage and liver function problems. It has been associated with aspirin consumption by children with viral illness, although it also occurs in the absence of aspirin use.

What is cerebrovascular disease?

An artery disease that is characterized by dysfunction of the blood vessels supplying the brain.

What is tyrosinemia type I?

A tyrosinemia that has_material_basis_in deficiency of the enzyme fumarylacetoacetate hydrolase resulting in an increase in fumarylacetoacetate which inhibits previous steps in tyrosine degradation leading to an accumulation of tyrosine in the body.

What is strongyloidiasis?

A parasitic helminthiasis infectious disease that involves infection of the intestine, lungs, skin and central nervous system with nematode Strongyloides stercoralis.

What is esophageal disease?

A gastrointestinal system disease that is located_in the esophagus.

What is postherpetic polyneuropathy?

A Varicellovirus infectious disease that results_in pain located_in nerve fiber, has_material_basis_in Human herpesvirus 3, which reactivates after the primary infection, has_symptom severe pain, has_symptom sensitivity to light touch, has_symptom muscle weakness, has_symptom paralysis, and has_symptom itching.

What is myelomeningocele?

A spina bifida characterized by protrusion of the spinal cord through an opening, covered by meningeal membranes.

What is acute laryngopharyngitis?

An upper respiratory tract disease which involves inflammation of both larynx and pharynx.

What is gastrointestinal carcinoma?

A gastrointestinal system cancer that has_material_basis_in epithelial cells.

What is ornithosis?

A primary bacterial infectious disease that results_in systemic infection, has_material_basis_in Chlamydia psittaci, which is transmitted_by inhaling aerosolized dried droppings or transmitted_by contact with infected birds. The infection has_symptom fever, has_symptom headache, has_symptom rash, has_symptom chills, and has_symptom pneumonia.

What is cellular schwannoma?

A neurilemmoma with a predominantly cellular growth but no Verocay bodies.

What is encephalitis?

Encephalitis is a nervous system infectious disease characterized as an acute inflammation of the brain. The usual cause is a viral infection, but bacteria can also cause it. Cases can range from mild to severe. For mild cases, you could have flu-like symptoms. Serious cases can cause severe headache, sudden fever, drowsiness, vomiting, confusion and seizures.

What is extraosseous chondrosarcoma?

A chondrosarcoma that is located_in exclusively soft tissue.

What is Aicardi-Goutieres syndrome?

An autosomal recessive disease that is a genetically heterogeneous encephalopathy characterized in its most severe form by cerebral atrophy, leukodystrophy, intracranial calcifications, chronic cerebrospinal fluid (CSF) lymphocytosis, increased CSF alpha-interferon, and negative serologic investigations for common prenatal infections.

What is selective IgM deficiency disease?

A selective immunoglobulin deficiency disease thatis a dysgammaglobulinemia resulting from decreased levels of immunoglobulin M (IgM) production to roduction of other antibodies.

What is vaginal carcinoma?

A vaginal cancer that has_material_basis_in epithelial cells.

What is recurrent nephroblastoma?

A nephroblastoma that recurs over time.

What is Hallermann-Streiff syndrome?

A syndrome that affects growth, cranial development, hair growth and dental development.

What is Conn's syndrome?

An adrenal admenoma characterized by over production of aldosterone.

What is Histoplasma capsulatum pericarditis?

An American histoplasmosis that results_in inflammation located_in pericardium, has_material_basis_in Histoplasma capsulatum var capsulatum, transmitted_by airborne spores and has_symptom pleural effusions, has_symptom chest pain and has_symptom cough.

What is infantile myofibromatosis?

A connective tissue benign neoplasm that is characterized by the development of benign tumors in the skin, striated muscles, bones, and in exceptional cases, visceral organs.

What is acromelic frontonasal dysostosis?

A dysostosis characterized by cranium bifidum, severe hypertelorism, median cleft lip and palate, nasal bifurcation, brachycephaly, large fontanelle, tibial hemimelia, preaxial polydactyly of the feet and brain malformations.

What is candidal endocarditis?

A candidiasis that results_in inflammation located_in endocardium, has_material_basis_in Candida, which favors previously damaged or prosthetic heart valves. The source is often an intravascular catheter or contaminated equipment used for illicit intravenous drug injection. The illness has_symptom fever, has_symptom murmur, has_symptom congestive heart failure, has_symptom anemia, and has_symptom splenomegaly.

What is verrucous carcinoma?

A squamous cell carcinoma that is a diffuse, papillary, non metastasizing, well differentiated, malignant neoplasm of epidermis or oral epithelium.

What is pertussis?

A commensal bacterial infectious disease that results_in inflammation located_in respiratory tract, has_material_basis_in Bordetella pertussis, or has_material_basis_in Bordetella parapertussis, which produce toxins that paralyze the cilia of the respiratory epithelial cells. The infection is characterized by a prolonged, high-pitched, deeply indrawn breath (whoop).

What is lipid pneumonia?

An aspiration pneumonitis resulting from the aspiration of lipids. It is the result of a foreign body-type reaction to the presence of lipid material within the lung parenchyma. It is caused by inhalation of nasal drops with oil base or cosmetic oil and aspiration of mineral oil when used as a laxative agent.

What is endogenous depression?

A mental depression that is characterized by a dysregulation of the endogenous opioid system and not of the monaminergic system.

What is pulmonary syphilis?

A tertiary syphilis that is caused by the spirochetal bacterium Treponema pallidum subspecies pallidum. It is a sexually transmitted disease although congenital syphilis can also occur. Treponema infection of the lung leads to a fibrous induration spreading from the roots of the lungs. Ulcerations occur in the superficial tissues, while in the deep tissues gummata are formed. Symptoms include dry cough, hemoptysis, hemorrhage, dyspnea, pain in the chest, loss of weight and slight fever.

What is autism spectrum disorder?

A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.

What is trichinosis?

A parasitic helminthiasis infectious disease that involves parasitic infection of animals and humans by Trichinella spiralis, Trichinella nativa or Trichinella britovi . Intestinal invasion causes diarrhea, abdominal pain and vomiting. Larval migration into muscle tissues can cause periorbital and facial edema, conjunctivitis, fever, myalgias, splinter hemorrhages, rashes, and blood eosinophilia. Myocarditis, central nervous system involvement, and pneumonitis can also occur.

What is notochordal cancer?

An embryonal cancer and bone cancer and mesenchymal cell neoplasm that is located_in the notochord.

What is dysgerminoma?

A germ cell cancer that derives_from cells that give rise to egg cells.

What is arthritis?

A bone inflammation disease that involves a response to irritation or injury, characterized by joint pain, swelling, stiffness located_in joint and/or redness located_in skin over the joint.

What is Simpson-Golabi-Behmel syndrome?

An X-linked disease characterized by pre- and postnatal overgrowth and craniofacial, skeletal, cardiac and renal abnormalities.

What is typhoidal tularemia?

A tularemia that results_in bacteremia and has_symptom fever, has_symptom chills, has_symptom myalgia, has_symptom malaise, and has_symptom weight loss.

What is acute hemorrhagic conjunctivitis?

A viral infectious disease that results_in inflammation located in conjunctiva, has_material_basis_in Human coxsackievirus A24 or has_material_basis_in Human enterovirus 70, which are transmitted_by contaminated fomites or transmitted_by contact with contaminated hands. The infection has_symptom vascular dilation, has_symptom eyelid edema, has_symptom photophobia, has_symptom redness of the eyes, has_symptom watering of the eye, has_symptom conjunctival congestion, and has_symptom superficial punctate epithelial keratitis.

What is swine influenza?

An influenza that results_in infection located_in respiratory tract of pigs and humans, has_material_basis_in Influenza C virus, or has_material_basis_in Influenza A virus subtypes (H1N1, H1N2, H3N1, H3N2, and H2N3), which are transmitted_by direct contact with infected pigs. The infection in humans has_symptom fever, has_symptom lethargy, has_symptom lack of appetite, has_symptom coughing, has_symptom runny nose, has_symptom sore throat, has_symptom nausea, has_symptom vomiting, and has_symptom diarrhea.

What is Ancylostoma ceylanicum ancylostomiasis?

An ancylostomiasis that involves parasitic infection of animals and humans by Ancylostoma ceylanicum larvae, which invade percutaneously and migrate to the intestine.

What is glucosephosphate dehydrogenase deficiency?

A carbohydrate metabolic disorder that is characterised by abnormally low levels of glucose-6-phosphate dehydrogenase (abbreviated G6PD or G6PDH).

What is acrodermatitis chronica atrophicans?

An acrodermatitis characterized by a chronically progressive course, leading to widespread atrophy of the skin. It is a clinical manifestation of Lyme borreliosis.

What is pineoblastoma?

A pineal gland neoplasm located_in the brain.

What is hair disease?

An integumentary system disease that is located_in hair.

What is infectious bovine rhinotracheitis?

A Varicellovirus infectious disease that results_in infection in cattle, located_in upper respiratory tract, and located_in genital tract, has_material_basis_in Bovine herpesvirus 1, has_symptom nasal discharge, has_symptom fever, has_symptom abortion, and has_symptom conjunctivitis.

What is lung disease?

A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide.

What is external ear carcinoma?

An external ear cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.

What is toxic shock syndrome?

A commensal bacterial infectious disease that results_in infection, has_material_basis_in Streptococcus pyogenes or has_material_basis_in Staphylococcus aureus , which produce toxins that are absorbed systemically and produce the systemic manifestations. The infection has_symptom fever, has_symptom rash, has_symptom hypotension, has_symptom multiorgan failure, has_symptom desquamation, has_symptom vomiting, has_symptom diarrhea, has_symptom headache, and has_symptom nonfocal neurologic abnormalities.

What is segmental dystonia?

A dystonia that affects two or more adjacent parts of the body.

What is acquired metabolic disease?

A disease of metabolism that has _material_basis_in enzyme deficiency or accumulation of enzymes or toxins which interfere with normal function due to an endocrine organ disease, organ malfunction, inadequate intake, dietary deficiency, or malabsorption.

What is melon allergy?

A fruit allergy triggered by Cucumis melo plant fruit food product.

What is conduct disorder?

A specific developmental disorder marked by a pattern of repetitive behavior wherein the rights of others or social norms are violated.

What is apricot allergy?

A fruit allergy triggered by Prunus armeniaca plant fruit food product.

What is vestibular neuronitis?

A inner ear infectious disease caused by a viral infection which involves inflammation of the vestibular nerve. It usually results as a complication of an upper respiratory infection. This causes sudden and severe vertigo, nausea and vomiting. Auditory symptoms are usually absent.

What is chicken egg allergy?

An egg allergy triggered by Gallus gallus eggs.

What is metachromatic leukodystrophy?

A sphingolipidosis characterized by the accumulation of sulfatides in cells, especially the myelin producing cells of the nervous system.

What is syndromic X-linked intellectual disability?

A syndromic intellectual characterized by an X-linked inheritance pattern.

What is echovirus meningitis?

A coxsackie meningitis that results_in inflammation located_in meningeal cluster, has_material_basis_in Human echovirus 30, or has_material_basis_in Human echovirus 9, which is transmitted_by ingestion of food contaminated with feces, transmitted_by droplet spread of oronasal secretions from infected person, or transmitted_by contaminated fomites. The infection has_symptom fever, has_symptom chills, has_symptom nausea, has_symptom headache, has_symptom photophobia and has_symptom neck stiffness.

What is suppurative otitis media?

A otitis media which involves inflammation of the middle ear with infected effusion containing pus.