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ADNI_114_S_6595_MR_Accelerated_Sagittal_MPRAGE__br_raw_20181127164633250_143_S752138_I1078739
On a T1-weighted brain MRI we observed: For the ventricles: - no appreciable enlargement noted in the 4th ventricle - mild enlargement of the right lateral ventricle; the left lateral ventricle is normal - no clear enlargement or abnormal growth seen in the 3rd ventricle - mild enlargement of the left inf. lateral ventricle and mild-to-moderate enlargement of the right inf. lateral ventricle - moderate-to-severe enlargement of the external csf For the cerebral cortex: - mild bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: anterior orbital gyrus (mild atrophy both left/right), gyrus rectus (normal-to-mild atrophy on the left and mild atrophy on the right), medial frontal cortex (mild atrophy on the left and normal-to-mild atrophy on the right), sup. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), precentral gyrus medial segment (normal on the left and mild atrophy on the right) and supplementary motor cortex (mild atrophy on the left) - the insular cortex shows no notable changes suggestive of atrophy - mild-to-moderate atrophy of the right limbic cortex; normal-to-mild atrophy of the left limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy both left/right) and parahippocampal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) - mild bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: inf. temporal gyrus (mild atrophy both left/right) and middle temporal gyrus (normal on the left and mild-to-moderate atrophy on the right) - mild bilateral atrophy of the parietal lobe; focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), postcentral gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and supramarginal gyrus (normal on the left and mild atrophy on the right) - no appreciable degenerative or atrophic changes observed in the occipital lobe For the subcortical structures: - mild-to-moderate atrophy of the left pallidum and mild atrophy of the right pallidum - mild atrophy of the left caudate and mild-to-moderate atrophy of the right caudate - moderate atrophy of the left amygdala and mild-to-moderate atrophy of the right amygdala - mild atrophy of the right thalamus; normal-to-mild atrophy of the left thalamus - mild-to-moderate atrophy of the left basal forebrain; the right basal forebrain is normal - mild-to-moderate atrophy of the left ventral dc and mild atrophy of the right ventral dc - mild-to-moderate atrophy of the left putamen and moderate atrophy of the right putamen - mild atrophy of the left hippocampus - mild atrophy of the right hippocampus - mild atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens
AD
FTLD_203875531_03137_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450288
On a T1-weighted brain MRI we observed: For the ventricles: - 3rd ventricle appears within normal size limits with no apparent enlargement - no appreciable enlargement noted in the lateral ventricle - no findings suggestive of enlargement are seen in the 4th ventricle - severe enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal - no observable enlargement of the external csf For the cerebral cortex: - moderate atrophy of the left temporal lobe; normal-to-mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy on the left), fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), planum polare (mild atrophy on the left and normal on the right) and middle temporal gyrus (mild atrophy on the left and normal on the right) - limbic cortex demonstrates a healthy morphology without signs of atrophy - frontal lobe appears within normal limits without apparent atrophy - occipital lobe appears preserved, with no observable tissue loss - parietal lobe appears within normal limits without apparent atrophy - no clear atrophic alterations are visible in the insular cortex For the subcortical structures: - severe atrophy of the left amygdala; the right amygdala is normal - basal forebrain maintains a normal appearance with no observable atrophic features - ventral dc maintains a normal appearance with no observable atrophic features - no evident atrophy or tissue thinning seen in the putamen - the left hippocampus volume is borderline low - no evident atrophy or tissue thinning seen in the accumbens - mild-to-moderate atrophy of the left pallidum; normal-to-mild atrophy of the right pallidum - the thalamus shows no notable changes suggestive of atrophy - no evident atrophy or tissue thinning seen in the caudate
SV
FTLD_203447962_03264_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10177413
On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild-to-moderate bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: entorhinal area (moderate atrophy both left/right), anterior cingulate gyrus (mild atrophy both left/right) and parahippocampal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) - mild atrophy of the left insular cortex and moderate atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and severe atrophy on the right) and posterior insula (mild atrophy on the left and mild-to-moderate atrophy on the right) - no observable atrophic changes in the parietal lobe - no observable atrophic changes in the occipital lobe - the frontal lobe shows no notable changes suggestive of atrophy - severe bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy both left/right), fusiform gyrus (mild-to-moderate atrophy on the left and moderate atrophy on the right), inf. temporal gyrus (mild-to-moderate atrophy on the left and moderate atrophy on the right), sup. temporal gyrus (mild atrophy on the left and moderate atrophy on the right) and middle temporal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right) For the subcortical structures: - severe bilateral atrophy of the amygdala - mild atrophy of the left pallidum and moderate atrophy of the right pallidum - mild atrophy of the left hippocampus - mild-to-moderate atrophy of the right hippocampus - moderate-to-severe atrophy of the left accumbens and severe atrophy of the right accumbens - no clear atrophic alterations are visible in the ventral dc - no findings suggestive of atrophy are seen in the thalamus - mild atrophy of the left putamen and severe atrophy of the right putamen - basal forebrain maintains a normal appearance with no observable atrophic features - mild-to-moderate atrophy of the left caudate and mild atrophy of the right caudate For the ventricles: - mild enlargement of the 3rd ventricle - no findings suggestive of enlargement are seen in the 4th ventricle - mild enlargement of the right lateral ventricle; the left lateral ventricle is normal - severe bilateral enlargement of the inf. lateral ventricle - mild enlargement of the external csf
SV
FTLD_203697146_02649_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177770
On a T1-weighted brain MRI we observed: For the ventricles: - external csf maintains its expected proportions without signs of enlargement - moderate-to-severe enlargement of the left inf. lateral ventricle and mild-to-moderate enlargement of the right inf. lateral ventricle - moderate enlargement of the 3rd ventricle - no findings suggestive of enlargement are seen in the 4th ventricle - severe bilateral enlargement of the lateral ventricle For the cerebral cortex: - no observable atrophic changes in the insular cortex - temporal lobe appears preserved, with no observable tissue loss - limbic cortex appears within normal limits without apparent atrophy - mild atrophy of the left parietal lobe; the right parietal lobe is normal; focal volume loss observed in the following subregions: supramarginal gyrus (mild atrophy on the left and normal on the right) - occipital lobe appears within normal limits without apparent atrophy - frontal lobe maintains a normal appearance with no observable atrophic features For the subcortical structures: - mild atrophy of the left hippocampus - the left hippocampus volume is borderline low - no clear atrophic alterations are visible in the ventral dc - the pallidum shows no notable changes suggestive of atrophy - mild-to-moderate atrophy of the left accumbens and moderate atrophy of the right accumbens - caudate appears within normal limits without apparent atrophy - no evident atrophy or tissue thinning seen in the thalamus - mild bilateral atrophy of the putamen - no clear atrophic alterations are visible in the basal forebrain - mild atrophy of the right amygdala; the left amygdala is normal
BV
ADNI_123_S_0113_MR_MPR____N3__Scaled_Br_20070731194237767_S12020_I63551
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no appreciable degenerative or atrophic changes observed in the occipital lobe - the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in precentral gyrus medial segment (moderate atrophy on the left and normal on the right), precentral gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), anterior orbital gyrus (mild atrophy on the left and normal on the right), supplementary motor cortex (normal on the left and mild atrophy on the right), sup. frontal gyrus (normal on the left and mild atrophy on the right) and sup. frontal gyrus medial segment (mild atrophy on the left) - temporal lobe appears within normal limits without apparent atrophy - mild atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: central operculum (mild atrophy both left/right) and parietal operculum (mild atrophy on the left and normal-to-mild atrophy on the right) - parietal lobe demonstrates a healthy morphology without signs of atrophy - mild atrophy of the left limbic cortex; normal-to-mild atrophy of the right limbic cortex; focal volume loss observed in the following subregions: parahippocampal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and posterior cingulate gyrus (mild atrophy on the left and normal on the right) For the ventricles: - severe enlargement of the left lateral ventricle and moderate enlargement of the right lateral ventricle - external csf maintains a typical volume without observable enlargement - mild-to-moderate enlargement of the 4th ventricle - mild enlargement of the 3rd ventricle - moderate enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle For the subcortical structures: - accumbens maintains a normal appearance with no observable atrophic features - no evident atrophy or tissue thinning seen in the basal forebrain - caudate appears within normal limits without apparent atrophy - pallidum appears within normal limits without apparent atrophy - ventral dc appears within normal limits without apparent atrophy - mild atrophy of the left hippocampus - mild atrophy of the right hippocampus - no findings suggestive of atrophy are seen in the thalamus - putamen appears within normal limits without apparent atrophy - amygdala appears preserved, with no observable tissue loss
CN
FTLD_203469454_01456_MR_Sagittal_MP-Rage_br_raw_20230206172857063_I10182094
On a T1-weighted brain MRI we observed: For the ventricles: - moderate-to-severe bilateral enlargement of the inf. lateral ventricle - no clear enlargement or abnormal growth seen in the 4th ventricle - mild-to-moderate enlargement of the 3rd ventricle - mild enlargement of the left lateral ventricle; normal-to-mild enlargement of the right lateral ventricle - external csf maintains a typical volume without observable enlargement For the subcortical structures: - basal forebrain appears within normal limits without apparent atrophy - moderate-to-severe bilateral atrophy of the amygdala - mild bilateral atrophy of the putamen - no appreciable degenerative or atrophic changes observed in the thalamus - ventral dc appears preserved, with no observable tissue loss - moderate atrophy of the left hippocampus - mild-to-moderate atrophy of the right hippocampus - mild bilateral atrophy of the accumbens - caudate appears within normal limits without apparent atrophy - no evident atrophy or tissue thinning seen in the pallidum For the cerebral cortex: - mild atrophy of the left insular cortex and mild-to-moderate atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and mild-to-moderate atrophy on the right) and central operculum (mild atrophy both left/right) - mild-to-moderate atrophy of the left temporal lobe and moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: inf. temporal gyrus (mild atrophy on the left and moderate atrophy on the right), middle temporal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right) and temporal pole (normal-to-mild atrophy on the left and mild atrophy on the right) - frontal lobe maintains a normal appearance with no observable atrophic features - mild-to-moderate atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild-to-moderate atrophy on the left), entorhinal area (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), middle cingulate gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right) and parahippocampal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) - no appreciable degenerative or atrophic changes observed in the occipital lobe - parietal lobe demonstrates a healthy morphology without signs of atrophy
SV
FTLD_203583546_01648_MR_Sagittal_MP-Rage_br_raw_20230206173833327_I10182163
On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild atrophy of the left insular cortex and moderate-to-severe atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and severe atrophy on the right), frontal operculum (mild atrophy on the left and moderate atrophy on the right) and posterior insula (mild atrophy on the left and mild-to-moderate atrophy on the right) - mild atrophy of the left frontal lobe and moderate-to-severe atrophy of the right frontal lobe; focal volume loss observed in the following subregions: medial orbital gyrus (mild atrophy on the left and moderate atrophy on the right), opercular inf. frontal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), gyrus rectus (mild atrophy on the left and mild-to-moderate atrophy on the right), medial frontal cortex (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), frontal pole (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), middle frontal gyrus (mild atrophy both left/right), sup. frontal gyrus (mild atrophy both left/right), posterior orbital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), triangular inf. frontal gyrus (normal on the left and mild atrophy on the right) and sup. frontal gyrus medial segment (normal on the left and mild atrophy on the right) - occipital lobe appears preserved, with no observable tissue loss - mild-to-moderate atrophy of the right temporal lobe; the left temporal lobe is normal; focal volume loss observed in the following subregions: inf. temporal gyrus (mild-to-moderate atrophy on the right), temporal pole (normal on the left and mild-to-moderate atrophy on the right), middle temporal gyrus (mild-to-moderate atrophy on the right) and planum polare (normal on the left and mild atrophy on the right) - mild-to-moderate atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy on the left and moderate atrophy on the right) and parahippocampal gyrus (normal on the left and mild-to-moderate atrophy on the right) - no evident atrophy or tissue thinning seen in the parietal lobe For the ventricles: - mild-to-moderate enlargement of the external csf - mild enlargement of the left lateral ventricle and moderate enlargement of the right lateral ventricle - no findings suggestive of enlargement are seen in the 4th ventricle - 3rd ventricle appears within normal size limits with no apparent enlargement - severe enlargement of the right inf. lateral ventricle; normal-to-mild enlargement of the left inf. lateral ventricle For the subcortical structures: - thalamus appears within normal limits without apparent atrophy - severe atrophy of the right amygdala; normal-to-mild atrophy of the left amygdala - mild-to-moderate atrophy of the left caudate and severe atrophy of the right caudate - mild atrophy of the right hippocampus - mild-to-moderate atrophy of the left accumbens and severe atrophy of the right accumbens - basal forebrain maintains a normal appearance with no observable atrophic features - no findings suggestive of atrophy are seen in the ventral dc - pallidum appears preserved, with no observable tissue loss - mild atrophy of the left putamen and moderate-to-severe atrophy of the right putamen
BV
ADNI_116_S_4010_MR_MPRAGE_br_raw_20110401094558289_2_S102845_I225667
On a T1-weighted brain MRI we observed: For the ventricles: - 4th ventricle appears to be of normal dimensions, with no observable increase in size - 3rd ventricle maintains a typical volume without observable enlargement - no observable enlargement of the external csf - no clear enlargement or abnormal growth seen in the inf. lateral ventricle - mild enlargement of the left lateral ventricle; the right lateral ventricle is normal For the subcortical structures: - no observable atrophic changes in the basal forebrain - mild-to-moderate atrophy of the left hippocampus - mild-to-moderate atrophy of the right hippocampus - amygdala appears preserved, with no observable tissue loss - thalamus appears preserved, with no observable tissue loss - ventral dc appears preserved, with no observable tissue loss - putamen demonstrates a healthy morphology without signs of atrophy - no clear atrophic alterations are visible in the caudate - mild atrophy of the left accumbens; the right accumbens is normal - pallidum demonstrates a healthy morphology without signs of atrophy For the cerebral cortex: - no clear atrophic alterations are visible in the frontal lobe - mild bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: transverse temporal gyrus (mild-to-moderate atrophy both left/right), sup. temporal gyrus (mild atrophy both left/right) and temporal pole (normal on the left and mild atrophy on the right) - no evident atrophy or tissue thinning seen in the insular cortex - occipital lobe demonstrates a healthy morphology without signs of atrophy - parietal lobe appears within normal limits without apparent atrophy - limbic cortex maintains a normal appearance with no observable atrophic features
CN
FTLD_203936524_01423_MR_Sagittal_MP-Rage_br_raw_20230206172842682_I10182092
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild-to-moderate atrophy of the right pallidum; the left pallidum is normal - no evident atrophy or tissue thinning seen in the thalamus - no clear atrophic alterations are visible in the basal forebrain - moderate-to-severe atrophy of the right putamen; normal-to-mild atrophy of the left putamen - mild-to-moderate atrophy of the left accumbens and severe atrophy of the right accumbens - ventral dc appears within normal limits without apparent atrophy - moderate atrophy of the right caudate; the left caudate is normal - mild-to-moderate atrophy of the left hippocampus - severe atrophy of the right hippocampus - severe bilateral atrophy of the amygdala For the ventricles: - 4th ventricle appears to be of normal dimensions, with no observable increase in size - mild-to-moderate enlargement of the external csf - moderate enlargement of the right lateral ventricle; normal-to-mild enlargement of the left lateral ventricle - severe bilateral enlargement of the inf. lateral ventricle - moderate enlargement of the 3rd ventricle For the cerebral cortex: - no evident atrophy or tissue thinning seen in the frontal lobe - the occipital lobe shows no notable changes suggestive of atrophy - the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in entorhinal area (mild-to-moderate atrophy on the left and moderate-to-severe atrophy on the right) and parahippocampal gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right) - moderate atrophy of the left temporal lobe and severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (mild-to-moderate atrophy on the left and severe atrophy on the right), middle temporal gyrus (mild atrophy on the left and severe atrophy on the right), fusiform gyrus (mild-to-moderate atrophy on the left and moderate atrophy on the right), inf. temporal gyrus (normal on the left and moderate-to-severe atrophy on the right), planum polare (normal on the left and mild-to-moderate atrophy on the right) and sup. temporal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) - mild atrophy of the right parietal lobe; the left parietal lobe is normal; focal volume loss observed in the following subregions: postcentral gyrus medial segment (mild-to-moderate atrophy on the left) and angular gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) - mild-to-moderate atrophy of the right insular cortex; the left insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and moderate-to-severe atrophy on the right), posterior insula (mild atrophy on the left and mild-to-moderate atrophy on the right) and central operculum (mild atrophy on the right)
SV
FTLD_203788719_01918_MR_Sagittal_MP-Rage_br_raw_20230206152255569_I10181377
On a T1-weighted brain MRI we observed: For the ventricles: - no observable enlargement of the lateral ventricle - the external csf shows no notable changes suggestive of enlargement - 3rd ventricle appears to be of normal dimensions, with no observable increase in size - 4th ventricle maintains a typical volume without observable enlargement - inf. lateral ventricle maintains its expected proportions without signs of enlargement For the subcortical structures: - no observable atrophic changes in the accumbens - no evident atrophy or tissue thinning seen in the pallidum - the hippocampus shows no notable changes suggestive of atrophy - the thalamus shows no notable changes suggestive of atrophy - mild atrophy of the left putamen; normal-to-mild atrophy of the right putamen - no appreciable degenerative or atrophic changes observed in the caudate - no evident atrophy or tissue thinning seen in the ventral dc - basal forebrain demonstrates a healthy morphology without signs of atrophy - no findings suggestive of atrophy are seen in the amygdala For the cerebral cortex: - mild atrophy of the left frontal lobe; normal-to-mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: precentral gyrus (moderate atrophy on the left and normal-to-mild atrophy on the right), sup. frontal gyrus medial segment (mild atrophy on the left and normal-to-mild atrophy on the right) and anterior orbital gyrus (mild atrophy on the right) - occipital lobe maintains a normal appearance with no observable atrophic features - moderate-to-severe atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: central operculum (moderate atrophy on the left and mild atrophy on the right), anterior insula (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) and parietal operculum (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) - no observable atrophic changes in the limbic cortex - no observable atrophic changes in the temporal lobe - no observable atrophic changes in the parietal lobe
PNFA
FTLD_203231766_02663_MR_Accelerated_Sagittal_MPRAGE_Repeat_br_raw_I10178175
On a T1-weighted brain MRI we observed: For the subcortical structures: - ventral dc appears within normal limits without apparent atrophy - the pallidum shows no notable changes suggestive of atrophy - no appreciable degenerative or atrophic changes observed in the basal forebrain - mild atrophy of the right putamen; normal-to-mild atrophy of the left putamen - thalamus demonstrates a healthy morphology without signs of atrophy - mild atrophy of the right caudate; the left caudate is normal - mild atrophy of the left accumbens and moderate atrophy of the right accumbens - mild-to-moderate atrophy of the right hippocampus - moderate-to-severe atrophy of the left amygdala and severe atrophy of the right amygdala For the cerebral cortex: - no clear atrophic alterations are visible in the occipital lobe - mild-to-moderate bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: parahippocampal gyrus (mild-to-moderate atrophy on the left and moderate atrophy on the right), entorhinal area (mild atrophy on the left and moderate atrophy on the right), middle cingulate gyrus (mild atrophy both left/right) and anterior cingulate gyrus (mild atrophy on the left and normal on the right) - no clear atrophic alterations are visible in the parietal lobe - mild atrophy of the right frontal lobe; the left frontal lobe is normal; focal volume loss observed in the following subregions: subcallosal area (mild atrophy on the left and mild-to-moderate atrophy on the right), frontal pole (mild atrophy both left/right), gyrus rectus (mild atrophy both left/right) and middle frontal gyrus (normal on the left and mild atrophy on the right) - moderate atrophy of the left temporal lobe and severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: middle temporal gyrus (mild atrophy on the left and moderate-to-severe atrophy on the right), temporal pole (mild atrophy on the left and moderate-to-severe atrophy on the right), fusiform gyrus (mild-to-moderate atrophy both left/right), inf. temporal gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right) and sup. temporal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) - mild-to-moderate atrophy of the right insular cortex; the left insular cortex is normal; focal volume loss observed in the following subregions: posterior insula (mild-to-moderate atrophy on the left and moderate-to-severe atrophy on the right), anterior insula (normal on the left and moderate atrophy on the right) and frontal operculum (normal-to-mild atrophy on the left and mild atrophy on the right) For the ventricles: - moderate enlargement of the right inf. lateral ventricle; the left inf. lateral ventricle is normal - no appreciable enlargement noted in the 4th ventricle - no clear enlargement or abnormal growth seen in the 3rd ventricle - lateral ventricle maintains a typical volume without observable enlargement - moderate enlargement of the external csf
SV
FTLD_203107266_02660_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177776
On a T1-weighted brain MRI we observed: For the ventricles: - no observable enlargement of the 4th ventricle - mild-to-moderate enlargement of the external csf - severe enlargement of the left inf. lateral ventricle and moderate enlargement of the right inf. lateral ventricle - mild-to-moderate enlargement of the 3rd ventricle - mild enlargement of the left lateral ventricle; normal-to-mild enlargement of the right lateral ventricle For the cerebral cortex: - severe atrophy of the left temporal lobe and moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (severe atrophy on the left and moderate atrophy on the right), sup. temporal gyrus (moderate-to-severe atrophy on the left and mild atrophy on the right), inf. temporal gyrus (mild-to-moderate atrophy both left/right), planum polare (moderate-to-severe atrophy on the left and normal on the right), fusiform gyrus (mild atrophy both left/right), middle temporal gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), planum temporale (mild-to-moderate atrophy on the left and normal on the right) and transverse temporal gyrus (mild atrophy on the left and normal on the right) - moderate-to-severe atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (moderate-to-severe atrophy on the left and mild atrophy on the right), anterior cingulate gyrus (moderate atrophy on the left and normal-to-mild atrophy on the right) and parahippocampal gyrus (moderate atrophy on the left and normal on the right) - frontal lobe appears preserved, with no observable tissue loss - occipital lobe appears within normal limits without apparent atrophy - no clear atrophic alterations are visible in the parietal lobe - severe atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: posterior insula (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), anterior insula (severe atrophy on the left and normal on the right), central operculum (mild atrophy on the left and normal-to-mild atrophy on the right), frontal operculum (mild-to-moderate atrophy on the left) and parietal operculum (mild atrophy on the left) For the subcortical structures: - thalamus demonstrates a healthy morphology without signs of atrophy - moderate atrophy of the left putamen; the right putamen is normal - no observable atrophic changes in the pallidum - no evident atrophy or tissue thinning seen in the caudate - moderate atrophy of the left hippocampus - basal forebrain maintains a normal appearance with no observable atrophic features - mild-to-moderate atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens - severe atrophy of the left amygdala and moderate-to-severe atrophy of the right amygdala - ventral dc maintains a normal appearance with no observable atrophic features
SV
FTLD_203918719_02911_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178103
On a T1-weighted brain MRI we observed: For the ventricles: - severe bilateral enlargement of the inf. lateral ventricle - the 4th ventricle shows no notable changes suggestive of enlargement - severe bilateral enlargement of the lateral ventricle - severe enlargement of the 3rd ventricle - moderate-to-severe enlargement of the external csf For the subcortical structures: - mild-to-moderate atrophy of the left pallidum and moderate-to-severe atrophy of the right pallidum - mild atrophy of the right thalamus; normal-to-mild atrophy of the left thalamus - severe atrophy of the left hippocampus - severe atrophy of the right hippocampus - severe bilateral atrophy of the accumbens - severe bilateral atrophy of the putamen - the basal forebrain shows no notable changes suggestive of atrophy - severe atrophy of the left amygdala and moderate-to-severe atrophy of the right amygdala - no findings suggestive of atrophy are seen in the ventral dc - severe bilateral atrophy of the caudate For the cerebral cortex: - moderate-to-severe bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: gyrus rectus (moderate atrophy both left/right), medial frontal cortex (moderate-to-severe atrophy on the left and mild atrophy on the right), sup. frontal gyrus medial segment (mild atrophy on the left and moderate atrophy on the right), medial orbital gyrus (mild-to-moderate atrophy both left/right), middle frontal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), anterior orbital gyrus (mild atrophy both left/right), posterior orbital gyrus (mild atrophy both left/right), orbital inf. frontal gyrus (mild-to-moderate atrophy on the left and normal on the right), lateral orbital gyrus (mild-to-moderate atrophy on the left and normal on the right), supplementary motor cortex (normal-to-mild atrophy on the left and mild atrophy on the right) and precentral gyrus medial segment (mild-to-moderate atrophy on the left) - moderate atrophy of the left insular cortex and moderate-to-severe atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and severe atrophy on the right), central operculum (mild atrophy on the left and mild-to-moderate atrophy on the right), frontal operculum (mild atrophy both left/right) and posterior insula (mild atrophy both left/right) - moderate bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (moderate-to-severe atrophy on the left and moderate atrophy on the right), middle cingulate gyrus (mild atrophy both left/right) and entorhinal area (normal-to-mild atrophy on the left and mild atrophy on the right) - mild atrophy of the right parietal lobe; the left parietal lobe is normal; focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and postcentral gyrus medial segment (mild atrophy on the left and normal on the right) - moderate-to-severe atrophy of the left temporal lobe and moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (severe atrophy on the left and moderate-to-severe atrophy on the right), middle temporal gyrus (moderate atrophy on the left and normal-to-mild atrophy on the right), fusiform gyrus (mild atrophy both left/right) and inf. temporal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) - occipital lobe appears preserved, with no observable tissue loss
BV
ADNI_033_S_6824_MR_Accelerated_Sagittal_MPRAGE__br_raw_20191001170054212_114_S879712_I1235084
On a T1-weighted brain MRI we observed: For the ventricles: - the external csf shows no notable changes suggestive of enlargement - lateral ventricle appears within normal size limits with no apparent enlargement - mild enlargement of the 3rd ventricle - no evident size increase noted in the inf. lateral ventricle - 4th ventricle maintains a typical volume without observable enlargement For the subcortical structures: - thalamus appears within normal limits without apparent atrophy - caudate maintains a normal appearance with no observable atrophic features - no findings suggestive of atrophy are seen in the ventral dc - no evident atrophy or tissue thinning seen in the accumbens - hippocampus appears within normal limits without apparent atrophy - amygdala appears within normal limits without apparent atrophy - no appreciable degenerative or atrophic changes observed in the basal forebrain - no evident atrophy or tissue thinning seen in the pallidum - no evident atrophy or tissue thinning seen in the putamen For the cerebral cortex: - limbic cortex appears within normal limits without apparent atrophy - no findings suggestive of atrophy are seen in the temporal lobe - occipital lobe appears within normal limits without apparent atrophy - no clear atrophic alterations are visible in the frontal lobe - no clear atrophic alterations are visible in the parietal lobe - no evident atrophy or tissue thinning seen in the insular cortex
AD
ADNI_037_S_10630_MR_Accelerated_Sagittal_MPRAGE_MSV21_br_raw_20250519190903829_1_I11282413
On a T1-weighted brain MRI we observed: For the subcortical structures: - accumbens appears within normal limits without apparent atrophy - hippocampus demonstrates a healthy morphology without signs of atrophy - putamen maintains a normal appearance with no observable atrophic features - pallidum demonstrates a healthy morphology without signs of atrophy - no findings suggestive of atrophy are seen in the basal forebrain - ventral dc appears within normal limits without apparent atrophy - no observable atrophic changes in the amygdala - thalamus appears preserved, with no observable tissue loss - no findings suggestive of atrophy are seen in the caudate For the cerebral cortex: - no clear atrophic alterations are visible in the limbic cortex - no appreciable degenerative or atrophic changes observed in the occipital lobe - no appreciable degenerative or atrophic changes observed in the parietal lobe - temporal lobe appears within normal limits without apparent atrophy - insular cortex appears within normal limits without apparent atrophy - the frontal lobe shows no notable changes suggestive of atrophy For the ventricles: - the 3rd ventricle shows no notable changes suggestive of enlargement - inf. lateral ventricle appears within normal size limits with no apparent enlargement - no observable enlargement of the 4th ventricle - no evident size increase noted in the lateral ventricle - external csf appears within normal size limits with no apparent enlargement
CN
FTLD_203285992_03298_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10177415
On a T1-weighted brain MRI we observed: For the subcortical structures: - severe atrophy of the left amygdala and moderate-to-severe atrophy of the right amygdala - moderate atrophy of the left pallidum; the right pallidum is normal - severe atrophy of the left putamen and mild atrophy of the right putamen - mild-to-moderate atrophy of the left hippocampus - the left hippocampus volume is borderline low - no observable atrophic changes in the ventral dc - severe atrophy of the left caudate and mild atrophy of the right caudate - severe atrophy of the left accumbens and moderate atrophy of the right accumbens - mild atrophy of the left thalamus; the right thalamus is normal - no findings suggestive of atrophy are seen in the basal forebrain For the ventricles: - moderate-to-severe enlargement of the left lateral ventricle and mild-to-moderate enlargement of the right lateral ventricle - mild enlargement of the 3rd ventricle - severe enlargement of the left inf. lateral ventricle and moderate-to-severe enlargement of the right inf. lateral ventricle - no findings suggestive of enlargement are seen in the 4th ventricle - mild enlargement of the external csf For the cerebral cortex: - no evident atrophy or tissue thinning seen in the occipital lobe - moderate atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (severe atrophy on the left and mild-to-moderate atrophy on the right), central operculum (mild atrophy on the left and normal-to-mild atrophy on the right) and posterior insula (mild atrophy on the left) - moderate atrophy of the left limbic cortex and mild-to-moderate atrophy of the right limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), entorhinal area (mild-to-moderate atrophy on the left and mild atrophy on the right), middle cingulate gyrus (mild atrophy on the left and normal on the right) and parahippocampal gyrus (mild atrophy on the left and normal on the right) - severe atrophy of the left temporal lobe; normal-to-mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), middle temporal gyrus (moderate atrophy on the left and normal on the right), fusiform gyrus (moderate atrophy on the left and normal on the right), inf. temporal gyrus (mild-to-moderate atrophy on the left) and planum temporale (mild atrophy on the left) - no findings suggestive of atrophy are seen in the parietal lobe - severe atrophy of the left frontal lobe; normal-to-mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: sup. frontal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), opercular inf. frontal gyrus (mild atrophy both left/right), medial frontal cortex (mild atrophy both left/right), lateral orbital gyrus (mild atrophy both left/right), supplementary motor cortex (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), gyrus rectus (mild-to-moderate atrophy on the left and normal on the right), medial orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), subcallosal area (mild atrophy on the left and normal-to-mild atrophy on the right), posterior orbital gyrus (mild atrophy on the left and normal on the right), precentral gyrus (mild atrophy on the left), sup. frontal gyrus medial segment (mild atrophy on the left), triangular inf. frontal gyrus (mild atrophy on the left) and middle frontal gyrus (mild atrophy on the left)
SV
ADNI_128_S_0310_MR_MPR__GradWarp__N3__Scaled_Br_20070819162315993_S12468_I68944
On a T1-weighted brain MRI we observed: For the cerebral cortex: - limbic cortex demonstrates a healthy morphology without signs of atrophy - the insular cortex shows no notable changes suggestive of atrophy - mild atrophy of the right frontal lobe; normal-to-mild atrophy of the left frontal lobe; focal volume loss observed in the following subregions: orbital inf. frontal gyrus (mild-to-moderate atrophy on the left and normal on the right), medial frontal cortex (normal-to-mild atrophy on the left and mild atrophy on the right), posterior orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), triangular inf. frontal gyrus (normal on the left and mild atrophy on the right), medial orbital gyrus (normal on the left and mild atrophy on the right) and precentral gyrus medial segment (mild atrophy on the right) - mild atrophy of the right temporal lobe; the left temporal lobe is normal; focal volume loss observed in the following subregions: middle temporal gyrus (mild atrophy both left/right) and sup. temporal gyrus (normal on the left and mild-to-moderate atrophy on the right) - the parietal lobe shows no notable changes suggestive of atrophy - no appreciable degenerative or atrophic changes observed in the occipital lobe For the subcortical structures: - putamen demonstrates a healthy morphology without signs of atrophy - mild atrophy of the left amygdala and moderate-to-severe atrophy of the right amygdala - no evident atrophy or tissue thinning seen in the caudate - thalamus maintains a normal appearance with no observable atrophic features - mild atrophy of the right accumbens; normal-to-mild atrophy of the left accumbens - pallidum appears preserved, with no observable tissue loss - mild atrophy of the left basal forebrain; the right basal forebrain is normal - mild-to-moderate atrophy of the left hippocampus - moderate-to-severe atrophy of the right hippocampus - ventral dc maintains a normal appearance with no observable atrophic features For the ventricles: - 3rd ventricle maintains a typical volume without observable enlargement - no observable enlargement of the external csf - no appreciable enlargement noted in the lateral ventricle - mild-to-moderate enlargement of the left inf. lateral ventricle and moderate enlargement of the right inf. lateral ventricle - mild enlargement of the 4th ventricle
AD
FTLD_203419597_02791_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177849
On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild-to-moderate atrophy of the left temporal lobe and severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate atrophy on the left and moderate-to-severe atrophy on the right), fusiform gyrus (mild-to-moderate atrophy on the left and moderate-to-severe atrophy on the right), middle temporal gyrus (normal-to-mild atrophy on the left and severe atrophy on the right), inf. temporal gyrus (normal on the left and moderate-to-severe atrophy on the right) and planum polare (normal on the left and moderate atrophy on the right) - moderate atrophy of the right occipital lobe; the left occipital lobe is normal; focal volume loss observed in the following subregions: calcarine cortex (mild-to-moderate atrophy both left/right), middle occipital gyrus (mild-to-moderate atrophy on the right), inf. occipital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), sup. occipital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), occipital pole (normal on the left and mild atrophy on the right) and occipital fusiform gyrus (mild atrophy on the right) - mild atrophy of the left limbic cortex and mild-to-moderate atrophy of the right limbic cortex; focal volume loss observed in the following subregions: entorhinal area (moderate atrophy on the left and severe atrophy on the right), parahippocampal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right) and anterior cingulate gyrus (mild atrophy both left/right) - mild atrophy of the right frontal lobe; the left frontal lobe is normal; focal volume loss observed in the following subregions: posterior orbital gyrus (mild atrophy both left/right), medial orbital gyrus (normal on the left and mild atrophy on the right), gyrus rectus (mild atrophy on the right) and triangular inf. frontal gyrus (mild atrophy on the right) - the parietal lobe shows no notable changes suggestive of atrophy - mild-to-moderate atrophy of the left insular cortex and severe atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (severe atrophy both left/right), posterior insula (mild atrophy on the left and severe atrophy on the right), parietal operculum (mild-to-moderate atrophy on the right) and frontal operculum (mild atrophy on the right) For the subcortical structures: - mild atrophy of the left pallidum and moderate atrophy of the right pallidum - no evident atrophy or tissue thinning seen in the basal forebrain - mild atrophy of the left thalamus and mild-to-moderate atrophy of the right thalamus - moderate-to-severe atrophy of the left accumbens and severe atrophy of the right accumbens - severe bilateral atrophy of the amygdala - moderate atrophy of the left caudate and moderate-to-severe atrophy of the right caudate - moderate-to-severe atrophy of the left hippocampus - severe atrophy of the right hippocampus - ventral dc appears within normal limits without apparent atrophy - moderate atrophy of the left putamen and severe atrophy of the right putamen For the ventricles: - mild-to-moderate enlargement of the external csf - severe enlargement of the left inf. lateral ventricle and moderate enlargement of the right inf. lateral ventricle - moderate-to-severe enlargement of the 3rd ventricle - severe bilateral enlargement of the lateral ventricle - the 4th ventricle shows no notable changes suggestive of enlargement
SV
FTLD_203199461_01169_MR_Sagittal_MP-Rage_br_raw_20230206170100687_I10181883
On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild atrophy of the right frontal lobe; normal-to-mild atrophy of the left frontal lobe; focal volume loss observed in the following subregions: posterior orbital gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), lateral orbital gyrus (mild atrophy both left/right), medial frontal cortex (mild atrophy on the right), gyrus rectus (normal on the left and mild atrophy on the right) and sup. frontal gyrus (normal on the left and mild atrophy on the right) - no observable atrophic changes in the parietal lobe - occipital lobe demonstrates a healthy morphology without signs of atrophy - mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the left and normal on the right), entorhinal area (mild atrophy on the left) and parahippocampal gyrus (mild atrophy on the left and normal on the right) - moderate-to-severe atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate atrophy on the left and mild-to-moderate atrophy on the right), fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), inf. temporal gyrus (mild-to-moderate atrophy on the left and normal on the right), planum polare (mild atrophy on the left), sup. temporal gyrus (mild atrophy on the left and normal on the right) and planum temporale (mild atrophy on the left and normal on the right) - mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: posterior insula (mild atrophy on the left and normal-to-mild atrophy on the right) and anterior insula (mild atrophy on the left and normal on the right) For the subcortical structures: - mild atrophy of the left putamen; normal-to-mild atrophy of the right putamen - mild atrophy of the left hippocampus - no clear atrophic alterations are visible in the ventral dc - mild-to-moderate atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens - caudate maintains a normal appearance with no observable atrophic features - no findings suggestive of atrophy are seen in the pallidum - severe atrophy of the left amygdala and mild atrophy of the right amygdala - thalamus demonstrates a healthy morphology without signs of atrophy - no appreciable degenerative or atrophic changes observed in the basal forebrain For the ventricles: - mild-to-moderate enlargement of the left lateral ventricle and mild enlargement of the right lateral ventricle - no evident size increase noted in the external csf - the 3rd ventricle shows no notable changes suggestive of enlargement - severe enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal - no evident size increase noted in the 4th ventricle
SV
FTLD_203697146_02649_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177770
On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild atrophy of the left parietal lobe; the right parietal lobe is normal; focal volume loss observed in the following subregions: supramarginal gyrus (mild atrophy on the left and normal on the right) - no appreciable degenerative or atrophic changes observed in the insular cortex - no evident atrophy or tissue thinning seen in the occipital lobe - limbic cortex demonstrates a healthy morphology without signs of atrophy - no findings suggestive of atrophy are seen in the frontal lobe - the temporal lobe shows no notable changes suggestive of atrophy For the subcortical structures: - mild atrophy of the right amygdala; the left amygdala is normal - mild atrophy of the left hippocampus - the left hippocampus volume is borderline low - mild-to-moderate atrophy of the left accumbens and moderate atrophy of the right accumbens - caudate appears within normal limits without apparent atrophy - thalamus demonstrates a healthy morphology without signs of atrophy - the pallidum shows no notable changes suggestive of atrophy - mild bilateral atrophy of the putamen - basal forebrain appears within normal limits without apparent atrophy - the ventral dc shows no notable changes suggestive of atrophy For the ventricles: - no clear enlargement or abnormal growth seen in the external csf - no evident size increase noted in the 4th ventricle - moderate enlargement of the 3rd ventricle - severe bilateral enlargement of the lateral ventricle - moderate-to-severe enlargement of the left inf. lateral ventricle and mild-to-moderate enlargement of the right inf. lateral ventricle
BV
FTLD_203032154_03453_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10450764
On a T1-weighted brain MRI we observed: For the subcortical structures: - no evident atrophy or tissue thinning seen in the basal forebrain - no appreciable degenerative or atrophic changes observed in the pallidum - mild atrophy of the left ventral dc; normal-to-mild atrophy of the right ventral dc - the amygdala shows no notable changes suggestive of atrophy - mild-to-moderate bilateral atrophy of the putamen - mild atrophy of the left accumbens; the right accumbens is normal - hippocampus maintains a normal appearance with no observable atrophic features - no appreciable degenerative or atrophic changes observed in the caudate - mild atrophy of the right thalamus; normal-to-mild atrophy of the left thalamus For the ventricles: - no observable enlargement of the 3rd ventricle - inf. lateral ventricle appears within normal size limits with no apparent enlargement - mild-to-moderate enlargement of the left lateral ventricle and mild enlargement of the right lateral ventricle - external csf appears to be of normal dimensions, with no observable increase in size - no observable enlargement of the 4th ventricle For the cerebral cortex: - no findings suggestive of atrophy are seen in the occipital lobe - the parietal lobe shows no notable changes suggestive of atrophy - no observable atrophic changes in the limbic cortex - no evident atrophy or tissue thinning seen in the frontal lobe - no clear atrophic alterations are visible in the insular cortex - temporal lobe appears within normal limits without apparent atrophy
CN
FTLD_203212277_03771_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10451144
On a T1-weighted brain MRI we observed: For the ventricles: - mild enlargement of the left lateral ventricle; the right lateral ventricle is normal - severe bilateral enlargement of the inf. lateral ventricle - 3rd ventricle maintains its expected proportions without signs of enlargement - 4th ventricle appears within normal size limits with no apparent enlargement - the external csf shows no notable changes suggestive of enlargement For the subcortical structures: - thalamus appears preserved, with no observable tissue loss - moderate atrophy of the left accumbens and mild atrophy of the right accumbens - basal forebrain demonstrates a healthy morphology without signs of atrophy - putamen appears within normal limits without apparent atrophy - mild atrophy of the left caudate; normal-to-mild atrophy of the right caudate - severe atrophy of the left amygdala and moderate-to-severe atrophy of the right amygdala - no findings suggestive of atrophy are seen in the pallidum - severe atrophy of the left hippocampus - the ventral dc shows no notable changes suggestive of atrophy For the cerebral cortex: - parietal lobe appears within normal limits without apparent atrophy - occipital lobe appears within normal limits without apparent atrophy - severe atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: middle temporal gyrus (moderate-to-severe atrophy on the left and normal-to-mild atrophy on the right), temporal pole (severe atrophy on the left and normal on the right), fusiform gyrus (moderate atrophy on the left and normal-to-mild atrophy on the right) and inf. temporal gyrus (moderate-to-severe atrophy on the left and normal on the right) - no clear atrophic alterations are visible in the frontal lobe - moderate-to-severe atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: posterior insula (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right) and anterior insula (severe atrophy on the left and normal-to-mild atrophy on the right) - moderate atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (moderate-to-severe atrophy on the left and mild atrophy on the right), parahippocampal gyrus (mild atrophy both left/right), anterior cingulate gyrus (mild-to-moderate atrophy on the left) and posterior cingulate gyrus (mild atrophy on the left and normal on the right)
SV
FTLD_203462328_01826_MR_Sagittal_MP-Rage_br_raw_20230206184146237_I10182619
On a T1-weighted brain MRI we observed: For the subcortical structures: - the left hippocampus volume is borderline low - the left hippocampus volume is borderline low - mild bilateral atrophy of the putamen - caudate appears preserved, with no observable tissue loss - mild bilateral atrophy of the pallidum - mild bilateral atrophy of the ventral dc - no evident atrophy or tissue thinning seen in the amygdala - no appreciable degenerative or atrophic changes observed in the basal forebrain - mild-to-moderate atrophy of the left accumbens and mild atrophy of the right accumbens - mild-to-moderate bilateral atrophy of the thalamus For the ventricles: - mild enlargement of the 3rd ventricle - mild-to-moderate enlargement of the external csf - mild enlargement of the left lateral ventricle; normal-to-mild enlargement of the right lateral ventricle - moderate enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle - mild-to-moderate enlargement of the 4th ventricle For the cerebral cortex: - no clear atrophic alterations are visible in the frontal lobe - no clear atrophic alterations are visible in the parietal lobe - mild atrophy of the right temporal lobe; normal-to-mild atrophy of the left temporal lobe; focal volume loss observed in the following subregions: middle temporal gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right) - no observable atrophic changes in the insular cortex - limbic cortex appears within normal limits without apparent atrophy - occipital lobe maintains a normal appearance with no observable atrophic features
BV
FTLD_203885066_01668_MR_Sagittal_MP-Rage_br_raw_20230124211959060_I10178604
On a T1-weighted brain MRI we observed: For the subcortical structures: - no clear atrophic alterations are visible in the pallidum - amygdala appears within normal limits without apparent atrophy - ventral dc appears within normal limits without apparent atrophy - accumbens maintains a normal appearance with no observable atrophic features - no observable atrophic changes in the basal forebrain - no findings suggestive of atrophy are seen in the thalamus - caudate maintains a normal appearance with no observable atrophic features - putamen appears within normal limits without apparent atrophy - no evident atrophy or tissue thinning seen in the hippocampus For the cerebral cortex: - no findings suggestive of atrophy are seen in the insular cortex - no evident atrophy or tissue thinning seen in the limbic cortex - the temporal lobe shows no notable changes suggestive of atrophy - the occipital lobe shows no notable changes suggestive of atrophy - parietal lobe appears preserved, with no observable tissue loss - no evident atrophy or tissue thinning seen in the frontal lobe For the ventricles: - no observable enlargement of the 3rd ventricle - no clear enlargement or abnormal growth seen in the lateral ventricle - no appreciable enlargement noted in the 4th ventricle - no evident size increase noted in the external csf - inf. lateral ventricle maintains a typical volume without observable enlargement
BV
FTLD_203936610_03013_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178074
On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild atrophy of the left limbic cortex and moderate-to-severe atrophy of the right limbic cortex; focal volume loss observed in the following subregions: entorhinal area (mild-to-moderate atrophy on the left and moderate atrophy on the right), parahippocampal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), anterior cingulate gyrus (normal on the left and mild-to-moderate atrophy on the right) and middle cingulate gyrus (normal on the left and mild-to-moderate atrophy on the right) - parietal lobe maintains a normal appearance with no observable atrophic features - no findings suggestive of atrophy are seen in the occipital lobe - no appreciable degenerative or atrophic changes observed in the frontal lobe - mild-to-moderate atrophy of the left temporal lobe and moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate atrophy on the left and moderate-to-severe atrophy on the right), middle temporal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), fusiform gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), planum polare (normal on the left and mild-to-moderate atrophy on the right) and inf. temporal gyrus (mild atrophy on the right) - mild-to-moderate atrophy of the left insular cortex and moderate atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and moderate atrophy on the right), parietal operculum (mild-to-moderate atrophy both left/right), posterior insula (mild atrophy on the left and mild-to-moderate atrophy on the right) and central operculum (mild atrophy on the right) For the ventricles: - moderate enlargement of the 3rd ventricle - mild enlargement of the 4th ventricle - severe bilateral enlargement of the inf. lateral ventricle - mild-to-moderate enlargement of the left lateral ventricle and moderate enlargement of the right lateral ventricle - mild enlargement of the external csf For the subcortical structures: - mild atrophy of the right caudate; the left caudate is normal - mild-to-moderate atrophy of the left hippocampus - moderate-to-severe atrophy of the right hippocampus - mild atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens - mild-to-moderate atrophy of the right pallidum; the left pallidum is normal - mild-to-moderate atrophy of the right putamen; normal-to-mild atrophy of the left putamen - mild atrophy of the left thalamus and mild-to-moderate atrophy of the right thalamus - no appreciable degenerative or atrophic changes observed in the basal forebrain - severe bilateral atrophy of the amygdala - ventral dc maintains a normal appearance with no observable atrophic features
BV
ADNI_127_S_4240_MR_Accelerated_Sag_IR-SPGR__br_raw_20120329160508522_109_S145195_I294276
On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy both left/right) - insular cortex appears preserved, with no observable tissue loss - mild atrophy of the left occipital lobe; the right occipital lobe is normal - the frontal lobe shows no notable changes suggestive of atrophy - temporal lobe appears within normal limits without apparent atrophy - parietal lobe appears within normal limits without apparent atrophy For the ventricles: - moderate enlargement of the 3rd ventricle - no observable enlargement of the lateral ventricle - severe enlargement of the left inf. lateral ventricle and mild-to-moderate enlargement of the right inf. lateral ventricle - no appreciable enlargement noted in the 4th ventricle - no appreciable enlargement noted in the external csf For the subcortical structures: - moderate atrophy of the left hippocampus - mild-to-moderate atrophy of the right hippocampus - no observable atrophic changes in the thalamus - mild-to-moderate bilateral atrophy of the caudate - basal forebrain maintains a normal appearance with no observable atrophic features - no evident atrophy or tissue thinning seen in the ventral dc - mild bilateral atrophy of the accumbens - mild atrophy of the left putamen; normal-to-mild atrophy of the right putamen - moderate atrophy of the left amygdala and mild atrophy of the right amygdala - pallidum maintains a normal appearance with no observable atrophic features
AD
ADNI_094_S_4089_MR_Accelerated_SAG_IR-SPGR__br_raw_20110630122131904_28_S113223_I242720
On a T1-weighted brain MRI we observed: For the ventricles: - no evident size increase noted in the 4th ventricle - lateral ventricle appears to be of normal dimensions, with no observable increase in size - moderate enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle - mild enlargement of the external csf - no appreciable enlargement noted in the 3rd ventricle For the subcortical structures: - severe atrophy of the left amygdala and mild-to-moderate atrophy of the right amygdala - no appreciable degenerative or atrophic changes observed in the basal forebrain - no appreciable degenerative or atrophic changes observed in the caudate - mild atrophy of the left thalamus; the right thalamus is normal - mild atrophy of the left putamen; normal-to-mild atrophy of the right putamen - mild atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens - no appreciable degenerative or atrophic changes observed in the pallidum - ventral dc appears within normal limits without apparent atrophy - mild-to-moderate atrophy of the left hippocampus - the left hippocampus volume is borderline low For the cerebral cortex: - mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: parahippocampal gyrus (mild atrophy both left/right) and posterior cingulate gyrus (mild atrophy on the left) - mild-to-moderate atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: temporal pole (mild-to-moderate atrophy on the left and mild atrophy on the right), planum polare (normal-to-mild atrophy on the left and mild atrophy on the right) and inf. temporal gyrus (mild atrophy on the left) - no appreciable degenerative or atrophic changes observed in the insular cortex - mild atrophy of the right parietal lobe; normal-to-mild atrophy of the left parietal lobe; focal volume loss observed in the following subregions: angular gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), precuneus (mild atrophy on the left and normal-to-mild atrophy on the right), postcentral gyrus medial segment (mild atrophy on the left and normal on the right) and sup. parietal lobule (mild atrophy on the left and normal on the right) - frontal lobe appears preserved, with no observable tissue loss - no findings suggestive of atrophy are seen in the occipital lobe
AD
ADNI_131_S_0441_MR_MPR__GradWarp__B1_Correction__N3__Scaled_Br_20070403135521962_S13681_I48029
On a T1-weighted brain MRI we observed: For the cerebral cortex: - the frontal lobe shows no notable changes suggestive of atrophy - limbic cortex appears within normal limits without apparent atrophy - parietal lobe appears preserved, with no observable tissue loss - insular cortex maintains a normal appearance with no observable atrophic features - no clear atrophic alterations are visible in the temporal lobe - no appreciable degenerative or atrophic changes observed in the occipital lobe For the ventricles: - no observable enlargement of the 4th ventricle - mild enlargement of the 3rd ventricle - external csf maintains its expected proportions without signs of enlargement - inf. lateral ventricle maintains its expected proportions without signs of enlargement - the lateral ventricle shows no notable changes suggestive of enlargement For the subcortical structures: - no observable atrophic changes in the accumbens - no observable atrophic changes in the pallidum - the basal forebrain shows no notable changes suggestive of atrophy - no clear atrophic alterations are visible in the ventral dc - the amygdala shows no notable changes suggestive of atrophy - no clear atrophic alterations are visible in the putamen - no clear atrophic alterations are visible in the caudate - no findings suggestive of atrophy are seen in the thalamus - no clear atrophic alterations are visible in the hippocampus
CN
ADNI_029_S_0914_MR_MT1__GradWarp__N3m_Br_20170516103723977_S470860_I851301
On a T1-weighted brain MRI we observed: For the ventricles: - severe bilateral enlargement of the inf. lateral ventricle - 4th ventricle appears within normal size limits with no apparent enlargement - no observable enlargement of the external csf - mild-to-moderate enlargement of the 3rd ventricle - mild enlargement of the right lateral ventricle; normal-to-mild enlargement of the left lateral ventricle For the cerebral cortex: - moderate-to-severe atrophy of the right temporal lobe; the left temporal lobe is normal; focal volume loss observed in the following subregions: inf. temporal gyrus (mild atrophy on the right), middle temporal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), sup. temporal gyrus (mild-to-moderate atrophy on the right), fusiform gyrus (mild atrophy both left/right) and transverse temporal gyrus (mild atrophy on the right) - mild-to-moderate atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (normal-to-mild atrophy on the left and moderate-to-severe atrophy on the right) and parahippocampal gyrus (normal on the left and mild-to-moderate atrophy on the right) - the parietal lobe shows no notable changes suggestive of atrophy - no observable atrophic changes in the frontal lobe - occipital lobe maintains a normal appearance with no observable atrophic features - mild atrophy of the right insular cortex; the left insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), frontal operculum (mild atrophy on the left and normal on the right) and posterior insula (mild atrophy on the right) For the subcortical structures: - mild atrophy of the right putamen; the left putamen is normal - mild bilateral atrophy of the pallidum - mild-to-moderate atrophy of the left caudate and mild atrophy of the right caudate - mild atrophy of the left ventral dc and mild-to-moderate atrophy of the right ventral dc - moderate-to-severe atrophy of the left amygdala and severe atrophy of the right amygdala - mild-to-moderate atrophy of the left hippocampus - moderate-to-severe atrophy of the right hippocampus - mild bilateral atrophy of the basal forebrain - mild atrophy of the left thalamus and moderate atrophy of the right thalamus - mild atrophy of the left accumbens and moderate atrophy of the right accumbens
AD
FTLD_203833156_02653_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178165
On a T1-weighted brain MRI we observed: For the subcortical structures: - the pallidum shows no notable changes suggestive of atrophy - the caudate shows no notable changes suggestive of atrophy - no evident atrophy or tissue thinning seen in the thalamus - ventral dc demonstrates a healthy morphology without signs of atrophy - mild-to-moderate atrophy of the left putamen; the right putamen is normal - severe atrophy of the left amygdala and moderate-to-severe atrophy of the right amygdala - mild-to-moderate atrophy of the left hippocampus - the left hippocampus volume is borderline low - mild-to-moderate atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens - no appreciable degenerative or atrophic changes observed in the basal forebrain For the cerebral cortex: - mild-to-moderate bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), posterior insula (moderate atrophy on the left and mild-to-moderate atrophy on the right), central operculum (mild atrophy on the right) and parietal operculum (normal on the left and mild atrophy on the right) - parietal lobe maintains a normal appearance with no observable atrophic features - occipital lobe maintains a normal appearance with no observable atrophic features - severe atrophy of the left temporal lobe and mild-to-moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), middle temporal gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), fusiform gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), planum temporale (normal-to-mild atrophy on the left and mild atrophy on the right), inf. temporal gyrus (mild-to-moderate atrophy on the left and normal on the right) and sup. temporal gyrus (mild-to-moderate atrophy on the left and normal on the right) - frontal lobe maintains a normal appearance with no observable atrophic features - mild atrophy of the right limbic cortex; normal-to-mild atrophy of the left limbic cortex; focal volume loss observed in the following subregions: entorhinal area (mild-to-moderate atrophy on the left and mild atrophy on the right) and parahippocampal gyrus (mild atrophy both left/right) For the ventricles: - mild enlargement of the external csf - no findings suggestive of enlargement are seen in the lateral ventricle - no evident size increase noted in the 3rd ventricle - severe enlargement of the left inf. lateral ventricle and mild-to-moderate enlargement of the right inf. lateral ventricle - no evident size increase noted in the 4th ventricle
SV
FTLD_203875531_03137_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450288
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no observable atrophic changes in the frontal lobe - moderate atrophy of the left temporal lobe; normal-to-mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy on the left), fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), planum polare (mild atrophy on the left and normal on the right) and middle temporal gyrus (mild atrophy on the left and normal on the right) - the occipital lobe shows no notable changes suggestive of atrophy - no appreciable degenerative or atrophic changes observed in the insular cortex - parietal lobe demonstrates a healthy morphology without signs of atrophy - limbic cortex demonstrates a healthy morphology without signs of atrophy For the ventricles: - severe enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal - the 3rd ventricle shows no notable changes suggestive of enlargement - no findings suggestive of enlargement are seen in the lateral ventricle - no clear enlargement or abnormal growth seen in the 4th ventricle - external csf appears within normal size limits with no apparent enlargement For the subcortical structures: - mild-to-moderate atrophy of the left pallidum; normal-to-mild atrophy of the right pallidum - severe atrophy of the left amygdala; the right amygdala is normal - the caudate shows no notable changes suggestive of atrophy - no clear atrophic alterations are visible in the ventral dc - accumbens appears preserved, with no observable tissue loss - basal forebrain appears preserved, with no observable tissue loss - the left hippocampus volume is borderline low - no findings suggestive of atrophy are seen in the thalamus - no clear atrophic alterations are visible in the putamen
SV
ADNI_168_S_6151_MR_Accelerated_Sagittal_MPRAGE__br_raw_20171219114009450_45_S645502_I947540
On a T1-weighted brain MRI we observed: For the cerebral cortex: - parietal lobe demonstrates a healthy morphology without signs of atrophy - mild atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: posterior cingulate gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and entorhinal area (mild atrophy on the left and normal on the right) - the insular cortex shows no notable changes suggestive of atrophy - the frontal lobe shows no notable changes suggestive of atrophy - temporal lobe maintains a normal appearance with no observable atrophic features - no findings suggestive of atrophy are seen in the occipital lobe For the subcortical structures: - ventral dc maintains a normal appearance with no observable atrophic features - no observable atrophic changes in the putamen - no observable atrophic changes in the caudate - basal forebrain demonstrates a healthy morphology without signs of atrophy - the amygdala shows no notable changes suggestive of atrophy - no evident atrophy or tissue thinning seen in the hippocampus - no appreciable degenerative or atrophic changes observed in the pallidum - no findings suggestive of atrophy are seen in the thalamus - accumbens appears preserved, with no observable tissue loss For the ventricles: - no clear enlargement or abnormal growth seen in the inf. lateral ventricle - no evident size increase noted in the 3rd ventricle - no findings suggestive of enlargement are seen in the external csf - lateral ventricle appears within normal size limits with no apparent enlargement - no clear enlargement or abnormal growth seen in the 4th ventricle
CN
FTLD_203204349_02940_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177888
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no findings suggestive of atrophy are seen in the temporal lobe - parietal lobe appears within normal limits without apparent atrophy - mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: frontal operculum (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) - moderate-to-severe atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: opercular inf. frontal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), middle frontal gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), lateral orbital gyrus (mild-to-moderate atrophy on the left and normal on the right), medial orbital gyrus (mild-to-moderate atrophy on the left), gyrus rectus (mild-to-moderate atrophy on the left), posterior orbital gyrus (mild atrophy on the left), sup. frontal gyrus (mild atrophy on the left), triangular inf. frontal gyrus (mild atrophy on the left), medial frontal cortex (mild atrophy on the left) and sup. frontal gyrus medial segment (mild atrophy on the left and normal on the right) - no findings suggestive of atrophy are seen in the occipital lobe - no observable atrophic changes in the limbic cortex For the ventricles: - external csf appears within normal size limits with no apparent enlargement - mild-to-moderate bilateral enlargement of the inf. lateral ventricle - mild-to-moderate enlargement of the left lateral ventricle and mild enlargement of the right lateral ventricle - mild enlargement of the 3rd ventricle - 4th ventricle maintains its expected proportions without signs of enlargement For the subcortical structures: - severe atrophy of the left caudate and mild-to-moderate atrophy of the right caudate - moderate-to-severe atrophy of the left accumbens and mild atrophy of the right accumbens - mild-to-moderate atrophy of the left thalamus; normal-to-mild atrophy of the right thalamus - mild atrophy of the left hippocampus - the left hippocampus volume is borderline low - basal forebrain maintains a normal appearance with no observable atrophic features - moderate atrophy of the left pallidum and mild-to-moderate atrophy of the right pallidum - the amygdala shows no notable changes suggestive of atrophy - moderate atrophy of the left ventral dc and mild atrophy of the right ventral dc - moderate-to-severe atrophy of the left putamen and mild atrophy of the right putamen
BV
FTLD_203212277_03771_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10451144
On a T1-weighted brain MRI we observed: For the subcortical structures: - ventral dc maintains a normal appearance with no observable atrophic features - no findings suggestive of atrophy are seen in the pallidum - the basal forebrain shows no notable changes suggestive of atrophy - severe atrophy of the left amygdala and moderate-to-severe atrophy of the right amygdala - moderate atrophy of the left accumbens and mild atrophy of the right accumbens - no appreciable degenerative or atrophic changes observed in the putamen - thalamus appears preserved, with no observable tissue loss - mild atrophy of the left caudate; normal-to-mild atrophy of the right caudate - severe atrophy of the left hippocampus For the cerebral cortex: - moderate-to-severe atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: posterior insula (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right) and anterior insula (severe atrophy on the left and normal-to-mild atrophy on the right) - the parietal lobe shows no notable changes suggestive of atrophy - no observable atrophic changes in the occipital lobe - moderate atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (moderate-to-severe atrophy on the left and mild atrophy on the right), parahippocampal gyrus (mild atrophy both left/right), anterior cingulate gyrus (mild-to-moderate atrophy on the left) and posterior cingulate gyrus (mild atrophy on the left and normal on the right) - no evident atrophy or tissue thinning seen in the frontal lobe - severe atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: middle temporal gyrus (moderate-to-severe atrophy on the left and normal-to-mild atrophy on the right), temporal pole (severe atrophy on the left and normal on the right), fusiform gyrus (moderate atrophy on the left and normal-to-mild atrophy on the right) and inf. temporal gyrus (moderate-to-severe atrophy on the left and normal on the right) For the ventricles: - no findings suggestive of enlargement are seen in the external csf - no evident size increase noted in the 4th ventricle - no appreciable enlargement noted in the 3rd ventricle - mild enlargement of the left lateral ventricle; the right lateral ventricle is normal - severe bilateral enlargement of the inf. lateral ventricle
SV
ADNI_021_S_1109_MR_MPR__GradWarp__N3__Scaled_Br_20070727185946236_S23446_I62695
On a T1-weighted brain MRI we observed: For the ventricles: - no clear enlargement or abnormal growth seen in the lateral ventricle - 4th ventricle appears within normal size limits with no apparent enlargement - mild enlargement of the right inf. lateral ventricle; the left inf. lateral ventricle is normal - moderate enlargement of the external csf - no evident size increase noted in the 3rd ventricle For the cerebral cortex: - mild-to-moderate atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (mild atrophy on the left and mild-to-moderate atrophy on the right), anterior cingulate gyrus (mild atrophy on the left), parahippocampal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and middle cingulate gyrus (mild atrophy on the left) - mild atrophy of the right insular cortex; the left insular cortex is normal; focal volume loss observed in the following subregions: posterior insula (mild atrophy both left/right) and central operculum (mild atrophy on the left and normal on the right) - the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in precentral gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), sup. frontal gyrus medial segment (mild atrophy on the right) and middle frontal gyrus (mild atrophy on the left and normal on the right) - mild-to-moderate atrophy of the right temporal lobe; the left temporal lobe is normal; focal volume loss observed in the following subregions: fusiform gyrus (mild atrophy both left/right), inf. temporal gyrus (normal on the left and mild atrophy on the right), middle temporal gyrus (normal on the left and mild atrophy on the right) and temporal pole (mild atrophy on the right) - moderate atrophy of the left parietal lobe and mild atrophy of the right parietal lobe; focal volume loss observed in the following subregions: angular gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) and precuneus (mild atrophy on the left and normal on the right) - no observable atrophic changes in the occipital lobe For the subcortical structures: - mild-to-moderate atrophy of the right hippocampus - basal forebrain appears preserved, with no observable tissue loss - pallidum appears preserved, with no observable tissue loss - no findings suggestive of atrophy are seen in the accumbens - no observable atrophic changes in the caudate - mild bilateral atrophy of the thalamus - putamen appears preserved, with no observable tissue loss - mild atrophy of the right ventral dc; normal-to-mild atrophy of the left ventral dc - mild atrophy of the left amygdala and moderate-to-severe atrophy of the right amygdala
AD
FTLD_203913818_02811_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10176891
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no observable atrophic changes in the occipital lobe - frontal lobe maintains a normal appearance with no observable atrophic features - parietal lobe appears preserved, with no observable tissue loss - limbic cortex maintains a normal appearance with no observable atrophic features - no evident atrophy or tissue thinning seen in the temporal lobe - insular cortex maintains a normal appearance with no observable atrophic features For the subcortical structures: - moderate-to-severe atrophy of the left pallidum and moderate atrophy of the right pallidum - no clear atrophic alterations are visible in the basal forebrain - mild-to-moderate atrophy of the left hippocampus - mild bilateral atrophy of the accumbens - moderate atrophy of the left thalamus and mild atrophy of the right thalamus - no findings suggestive of atrophy are seen in the amygdala - mild bilateral atrophy of the putamen - mild atrophy of the left caudate; the right caudate is normal - ventral dc demonstrates a healthy morphology without signs of atrophy For the ventricles: - no evident size increase noted in the 4th ventricle - external csf appears within normal size limits with no apparent enlargement - no appreciable enlargement noted in the inf. lateral ventricle - mild-to-moderate bilateral enlargement of the lateral ventricle - 3rd ventricle maintains its expected proportions without signs of enlargement
BV
FTLD_203764653_03356_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10450598
On a T1-weighted brain MRI we observed: For the subcortical structures: - caudate appears preserved, with no observable tissue loss - no appreciable degenerative or atrophic changes observed in the amygdala - basal forebrain appears within normal limits without apparent atrophy - no findings suggestive of atrophy are seen in the putamen - ventral dc appears preserved, with no observable tissue loss - accumbens appears within normal limits without apparent atrophy - no observable atrophic changes in the pallidum - no observable atrophic changes in the thalamus - no observable atrophic changes in the hippocampus For the ventricles: - mild-to-moderate enlargement of the 3rd ventricle - no clear enlargement or abnormal growth seen in the inf. lateral ventricle - 4th ventricle appears within normal size limits with no apparent enlargement - no findings suggestive of enlargement are seen in the external csf - lateral ventricle appears within normal size limits with no apparent enlargement For the cerebral cortex: - no appreciable degenerative or atrophic changes observed in the insular cortex - parietal lobe appears within normal limits without apparent atrophy - no clear atrophic alterations are visible in the frontal lobe - occipital lobe demonstrates a healthy morphology without signs of atrophy - temporal lobe appears preserved, with no observable tissue loss - no clear atrophic alterations are visible in the limbic cortex
BV
FTLD_203447962_03264_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10177413
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild atrophy of the left hippocampus - mild-to-moderate atrophy of the right hippocampus - no clear atrophic alterations are visible in the basal forebrain - severe bilateral atrophy of the amygdala - mild atrophy of the left putamen and severe atrophy of the right putamen - mild atrophy of the left pallidum and moderate atrophy of the right pallidum - mild-to-moderate atrophy of the left caudate and mild atrophy of the right caudate - moderate-to-severe atrophy of the left accumbens and severe atrophy of the right accumbens - no evident atrophy or tissue thinning seen in the thalamus - no observable atrophic changes in the ventral dc For the ventricles: - severe bilateral enlargement of the inf. lateral ventricle - 4th ventricle appears within normal size limits with no apparent enlargement - mild enlargement of the external csf - mild enlargement of the right lateral ventricle; the left lateral ventricle is normal - mild enlargement of the 3rd ventricle For the cerebral cortex: - occipital lobe appears within normal limits without apparent atrophy - mild atrophy of the left insular cortex and moderate atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and severe atrophy on the right) and posterior insula (mild atrophy on the left and mild-to-moderate atrophy on the right) - severe bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy both left/right), fusiform gyrus (mild-to-moderate atrophy on the left and moderate atrophy on the right), inf. temporal gyrus (mild-to-moderate atrophy on the left and moderate atrophy on the right), sup. temporal gyrus (mild atrophy on the left and moderate atrophy on the right) and middle temporal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right) - mild-to-moderate bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: entorhinal area (moderate atrophy both left/right), anterior cingulate gyrus (mild atrophy both left/right) and parahippocampal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) - no observable atrophic changes in the frontal lobe - parietal lobe appears within normal limits without apparent atrophy
SV
FTLD_203177063_03367_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10450616
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild bilateral atrophy of the amygdala - no observable atrophic changes in the basal forebrain - no evident atrophy or tissue thinning seen in the pallidum - hippocampus appears within normal limits without apparent atrophy - mild bilateral atrophy of the accumbens - no observable atrophic changes in the thalamus - mild atrophy of the left caudate; the right caudate is normal - no clear atrophic alterations are visible in the ventral dc - mild atrophy of the left putamen; the right putamen is normal For the ventricles: - the inf. lateral ventricle shows no notable changes suggestive of enlargement - no evident size increase noted in the 4th ventricle - the lateral ventricle shows no notable changes suggestive of enlargement - 3rd ventricle appears within normal size limits with no apparent enlargement - mild enlargement of the external csf For the cerebral cortex: - mild bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: inf. temporal gyrus (mild atrophy both left/right) - mild-to-moderate atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (severe atrophy on the left and moderate atrophy on the right) and frontal operculum (mild-to-moderate atrophy on the left and mild atrophy on the right) - no evident atrophy or tissue thinning seen in the occipital lobe - the limbic cortex shows no notable changes suggestive of atrophy - no evident atrophy or tissue thinning seen in the parietal lobe - mild-to-moderate atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: sup. frontal gyrus (mild atrophy on the left), opercular inf. frontal gyrus (mild-to-moderate atrophy on the left and normal on the right), posterior orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. frontal gyrus medial segment (mild atrophy on the left and normal-to-mild atrophy on the right), frontal pole (mild atrophy on the left and normal on the right), medial frontal cortex (mild atrophy on the left and normal on the right), medial orbital gyrus (mild atrophy on the left and normal on the right) and gyrus rectus (mild atrophy on the right)
PNFA
FTLD_203307240_03040_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10177390
On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and normal on the right) - severe atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (severe atrophy on the left and mild atrophy on the right), fusiform gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), inf. temporal gyrus (moderate atrophy on the left), planum polare (mild-to-moderate atrophy on the left and normal on the right), sup. temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), transverse temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), planum temporale (normal on the left and mild atrophy on the right) and middle temporal gyrus (mild atrophy on the left) - no appreciable degenerative or atrophic changes observed in the parietal lobe - the frontal lobe shows no notable changes suggestive of atrophy - mild atrophy of the left limbic cortex; normal-to-mild atrophy of the right limbic cortex; focal volume loss observed in the following subregions: entorhinal area (mild atrophy on the left and normal-to-mild atrophy on the right) - no observable atrophic changes in the occipital lobe For the ventricles: - no observable enlargement of the external csf - mild enlargement of the left lateral ventricle; the right lateral ventricle is normal - no findings suggestive of enlargement are seen in the 4th ventricle - 3rd ventricle appears to be of normal dimensions, with no observable increase in size - moderate-to-severe enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal For the subcortical structures: - no observable atrophic changes in the thalamus - no evident atrophy or tissue thinning seen in the putamen - moderate-to-severe atrophy of the left amygdala and mild-to-moderate atrophy of the right amygdala - no evident atrophy or tissue thinning seen in the basal forebrain - caudate appears within normal limits without apparent atrophy - accumbens appears preserved, with no observable tissue loss - mild atrophy of the left ventral dc; the right ventral dc is normal - mild atrophy of the left hippocampus - mild atrophy of the left pallidum; the right pallidum is normal
SV
FTLD_203774517_02717_MR_Accelerated_Sagittal_IR-FSPGR_br_raw_202_I10176958
On a T1-weighted brain MRI we observed: For the cerebral cortex: - temporal lobe demonstrates a healthy morphology without signs of atrophy - no appreciable degenerative or atrophic changes observed in the parietal lobe - no evident atrophy or tissue thinning seen in the frontal lobe - no evident atrophy or tissue thinning seen in the insular cortex - no observable atrophic changes in the occipital lobe - no observable atrophic changes in the limbic cortex For the subcortical structures: - the basal forebrain shows no notable changes suggestive of atrophy - mild atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens - mild atrophy of the left putamen; normal-to-mild atrophy of the right putamen - mild atrophy of the left caudate; normal-to-mild atrophy of the right caudate - amygdala demonstrates a healthy morphology without signs of atrophy - the left hippocampus volume is borderline low - mild atrophy of the left thalamus; normal-to-mild atrophy of the right thalamus - ventral dc demonstrates a healthy morphology without signs of atrophy - mild bilateral atrophy of the pallidum For the ventricles: - no findings suggestive of enlargement are seen in the 3rd ventricle - mild-to-moderate enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal - the 4th ventricle shows no notable changes suggestive of enlargement - mild enlargement of the external csf - mild-to-moderate enlargement of the left lateral ventricle; the right lateral ventricle is normal
PNFA
FTLD_203881724_03428_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10450716
On a T1-weighted brain MRI we observed: For the subcortical structures: - ventral dc appears preserved, with no observable tissue loss - no findings suggestive of atrophy are seen in the thalamus - accumbens demonstrates a healthy morphology without signs of atrophy - mild atrophy of the right basal forebrain; the left basal forebrain is normal - hippocampus maintains a normal appearance with no observable atrophic features - amygdala appears preserved, with no observable tissue loss - pallidum appears within normal limits without apparent atrophy - mild atrophy of the left caudate; normal-to-mild atrophy of the right caudate - no findings suggestive of atrophy are seen in the putamen For the ventricles: - the 3rd ventricle shows no notable changes suggestive of enlargement - lateral ventricle maintains its expected proportions without signs of enlargement - no findings suggestive of enlargement are seen in the 4th ventricle - inf. lateral ventricle maintains its expected proportions without signs of enlargement - external csf maintains a typical volume without observable enlargement For the cerebral cortex: - occipital lobe appears preserved, with no observable tissue loss - temporal lobe appears within normal limits without apparent atrophy - parietal lobe appears preserved, with no observable tissue loss - insular cortex demonstrates a healthy morphology without signs of atrophy - no observable atrophic changes in the frontal lobe - no observable atrophic changes in the limbic cortex
CN
ADNI_130_S_4990_MR_MPRAGE_br_raw_20121029151935426_15_S172518_I342911
On a T1-weighted brain MRI we observed: For the ventricles: - mild enlargement of the 3rd ventricle - mild bilateral enlargement of the inf. lateral ventricle - 4th ventricle maintains a typical volume without observable enlargement - mild enlargement of the external csf - mild enlargement of the left lateral ventricle and mild-to-moderate enlargement of the right lateral ventricle For the cerebral cortex: - temporal lobe appears within normal limits without apparent atrophy - no evident atrophy or tissue thinning seen in the limbic cortex - no findings suggestive of atrophy are seen in the insular cortex - mild bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: opercular inf. frontal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), medial orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), posterior orbital gyrus (mild atrophy on the right) and orbital inf. frontal gyrus (mild atrophy on the right) - no observable atrophic changes in the occipital lobe - mild atrophy of the right parietal lobe; normal-to-mild atrophy of the left parietal lobe; focal volume loss observed in the following subregions: supramarginal gyrus (mild atrophy on the left and normal on the right) For the subcortical structures: - mild atrophy of the left pallidum; normal-to-mild atrophy of the right pallidum - ventral dc appears within normal limits without apparent atrophy - no findings suggestive of atrophy are seen in the thalamus - mild bilateral atrophy of the putamen - mild atrophy of the right caudate; normal-to-mild atrophy of the left caudate - the basal forebrain shows no notable changes suggestive of atrophy - mild-to-moderate atrophy of the left accumbens and mild atrophy of the right accumbens - mild atrophy of the left hippocampus - mild atrophy of the right hippocampus - mild bilateral atrophy of the amygdala
AD
FTLD_203884715_02518_MR_Sagittal_MP-Rage_br_raw_20230206161048123_I10181559
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild-to-moderate atrophy of the left caudate and mild atrophy of the right caudate - mild-to-moderate bilateral atrophy of the accumbens - the left hippocampus volume is borderline low - the left hippocampus volume is borderline low - no appreciable degenerative or atrophic changes observed in the ventral dc - basal forebrain appears preserved, with no observable tissue loss - mild atrophy of the left pallidum; the right pallidum is normal - amygdala appears within normal limits without apparent atrophy - no observable atrophic changes in the thalamus - mild-to-moderate atrophy of the left putamen and mild atrophy of the right putamen For the cerebral cortex: - mild bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), sup. frontal gyrus (mild atrophy both left/right) and medial frontal cortex (mild atrophy on the left and normal-to-mild atrophy on the right) - mild-to-moderate atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: sup. temporal gyrus (mild atrophy both left/right), temporal pole (mild atrophy both left/right), middle temporal gyrus (mild-to-moderate atrophy on the left and normal on the right), transverse temporal gyrus (mild-to-moderate atrophy on the right), planum temporale (normal on the left and mild atrophy on the right) and inf. temporal gyrus (mild atrophy on the left) - mild atrophy of the left limbic cortex; normal-to-mild atrophy of the right limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy both left/right) - insular cortex demonstrates a healthy morphology without signs of atrophy - no observable atrophic changes in the occipital lobe - parietal lobe demonstrates a healthy morphology without signs of atrophy For the ventricles: - no appreciable enlargement noted in the 3rd ventricle - mild enlargement of the external csf - no evident size increase noted in the 4th ventricle - severe enlargement of the left inf. lateral ventricle and moderate enlargement of the right inf. lateral ventricle - mild-to-moderate enlargement of the left lateral ventricle and mild enlargement of the right lateral ventricle
BV
ADNI_116_S_1083_MR_MPR__GradWarp__N3_Br_20070812145913579_S22373_I67240
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild atrophy of the left hippocampus - thalamus appears preserved, with no observable tissue loss - the accumbens shows no notable changes suggestive of atrophy - no clear atrophic alterations are visible in the basal forebrain - putamen appears preserved, with no observable tissue loss - no clear atrophic alterations are visible in the amygdala - pallidum maintains a normal appearance with no observable atrophic features - no findings suggestive of atrophy are seen in the caudate - no appreciable degenerative or atrophic changes observed in the ventral dc For the cerebral cortex: - occipital lobe maintains a normal appearance with no observable atrophic features - frontal lobe demonstrates a healthy morphology without signs of atrophy - no appreciable degenerative or atrophic changes observed in the limbic cortex - temporal lobe maintains a normal appearance with no observable atrophic features - parietal lobe maintains a normal appearance with no observable atrophic features - no clear atrophic alterations are visible in the insular cortex For the ventricles: - lateral ventricle maintains its expected proportions without signs of enlargement - inf. lateral ventricle maintains its expected proportions without signs of enlargement - the 3rd ventricle shows no notable changes suggestive of enlargement - 4th ventricle appears within normal size limits with no apparent enlargement - the external csf shows no notable changes suggestive of enlargement
AD
FTLD_203764653_03356_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10450598
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no findings suggestive of atrophy are seen in the insular cortex - no observable atrophic changes in the occipital lobe - parietal lobe demonstrates a healthy morphology without signs of atrophy - temporal lobe maintains a normal appearance with no observable atrophic features - the limbic cortex shows no notable changes suggestive of atrophy - no clear atrophic alterations are visible in the frontal lobe For the subcortical structures: - accumbens appears preserved, with no observable tissue loss - no observable atrophic changes in the ventral dc - amygdala appears preserved, with no observable tissue loss - no observable atrophic changes in the putamen - basal forebrain demonstrates a healthy morphology without signs of atrophy - no observable atrophic changes in the hippocampus - no evident atrophy or tissue thinning seen in the caudate - no observable atrophic changes in the thalamus - pallidum appears within normal limits without apparent atrophy For the ventricles: - inf. lateral ventricle maintains a typical volume without observable enlargement - mild-to-moderate enlargement of the 3rd ventricle - lateral ventricle maintains its expected proportions without signs of enlargement - no observable enlargement of the external csf - no clear enlargement or abnormal growth seen in the 4th ventricle
BV
FTLD_203807239_02930_MR_Accelerated_Sagittal_IR-FSPGR_br_raw_202_I10176979
On a T1-weighted brain MRI we observed: For the subcortical structures: - no appreciable degenerative or atrophic changes observed in the thalamus - mild-to-moderate atrophy of the left caudate and mild atrophy of the right caudate - no observable atrophic changes in the basal forebrain - moderate atrophy of the left putamen; normal-to-mild atrophy of the right putamen - mild-to-moderate atrophy of the left pallidum; normal-to-mild atrophy of the right pallidum - amygdala maintains a normal appearance with no observable atrophic features - no clear atrophic alterations are visible in the ventral dc - mild atrophy of the right accumbens; normal-to-mild atrophy of the left accumbens - the left hippocampus volume is borderline low For the cerebral cortex: - no findings suggestive of atrophy are seen in the parietal lobe - no evident atrophy or tissue thinning seen in the occipital lobe - no evident atrophy or tissue thinning seen in the insular cortex - moderate-to-severe atrophy of the left frontal lobe and mild-to-moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), frontal pole (mild atrophy both left/right), orbital inf. frontal gyrus (mild atrophy both left/right), sup. frontal gyrus (mild atrophy both left/right), opercular inf. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), lateral orbital gyrus (normal on the left and mild-to-moderate atrophy on the right), anterior orbital gyrus (normal on the left and mild atrophy on the right), precentral gyrus (mild atrophy on the left and normal on the right) and supplementary motor cortex (mild atrophy on the left) - limbic cortex appears within normal limits without apparent atrophy - no clear atrophic alterations are visible in the temporal lobe For the ventricles: - mild bilateral enlargement of the lateral ventricle - 3rd ventricle appears to be of normal dimensions, with no observable increase in size - mild-to-moderate bilateral enlargement of the inf. lateral ventricle - mild-to-moderate enlargement of the external csf - no clear enlargement or abnormal growth seen in the 4th ventricle
PNFA
FTLD_203192236_02639_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177752
On a T1-weighted brain MRI we observed: For the subcortical structures: - moderate atrophy of the left hippocampus - moderate atrophy of the right hippocampus - moderate atrophy of the left putamen and mild-to-moderate atrophy of the right putamen - moderate-to-severe atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens - mild-to-moderate bilateral atrophy of the pallidum - the ventral dc shows no notable changes suggestive of atrophy - moderate atrophy of the left caudate and moderate-to-severe atrophy of the right caudate - moderate-to-severe bilateral atrophy of the amygdala - no observable atrophic changes in the basal forebrain - mild-to-moderate bilateral atrophy of the thalamus For the ventricles: - mild bilateral enlargement of the lateral ventricle - mild-to-moderate enlargement of the external csf - severe enlargement of the 3rd ventricle - severe bilateral enlargement of the inf. lateral ventricle - no evident size increase noted in the 4th ventricle For the cerebral cortex: - mild atrophy of the left temporal lobe and moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (mild atrophy on the left and moderate atrophy on the right), middle temporal gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and inf. temporal gyrus (normal on the left and mild atrophy on the right) - no appreciable degenerative or atrophic changes observed in the parietal lobe - mild atrophy of the right insular cortex; the left insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (mild-to-moderate atrophy on the left and moderate atrophy on the right) - occipital lobe demonstrates a healthy morphology without signs of atrophy - mild atrophy of the left frontal lobe and moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: gyrus rectus (mild atrophy both left/right), sup. frontal gyrus (mild atrophy both left/right), medial frontal cortex (mild atrophy on the left and normal-to-mild atrophy on the right), middle frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), posterior orbital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and triangular inf. frontal gyrus (normal on the left and mild atrophy on the right) - no findings suggestive of atrophy are seen in the limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy both left/right)
BV
FTLD_203664697_01796_MR_Sagittal_MP-Rage_br_raw_20230206151537740_I10181354
On a T1-weighted brain MRI we observed: For the ventricles: - external csf maintains its expected proportions without signs of enlargement - no clear enlargement or abnormal growth seen in the inf. lateral ventricle - lateral ventricle maintains its expected proportions without signs of enlargement - no observable enlargement of the 4th ventricle - no clear enlargement or abnormal growth seen in the 3rd ventricle For the subcortical structures: - no clear atrophic alterations are visible in the hippocampus - caudate appears within normal limits without apparent atrophy - the accumbens shows no notable changes suggestive of atrophy - the ventral dc shows no notable changes suggestive of atrophy - mild bilateral atrophy of the basal forebrain - the thalamus shows no notable changes suggestive of atrophy - putamen maintains a normal appearance with no observable atrophic features - the amygdala shows no notable changes suggestive of atrophy - pallidum maintains a normal appearance with no observable atrophic features For the cerebral cortex: - limbic cortex maintains a normal appearance with no observable atrophic features - temporal lobe maintains a normal appearance with no observable atrophic features - no findings suggestive of atrophy are seen in the frontal lobe - no appreciable degenerative or atrophic changes observed in the occipital lobe - no appreciable degenerative or atrophic changes observed in the parietal lobe - no observable atrophic changes in the insular cortex
CN
FTLD_203260125_02526_MR_Sagittal_MP-Rage_br_raw_20230206161248652_I10181566
On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: frontal operculum (mild atrophy both left/right) and parietal operculum (mild atrophy on the left and normal-to-mild atrophy on the right) - occipital lobe maintains a normal appearance with no observable atrophic features - mild atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: fusiform gyrus (mild-to-moderate atrophy both left/right), transverse temporal gyrus (mild atrophy on the right), planum temporale (normal-to-mild atrophy on the left and mild atrophy on the right) and sup. temporal gyrus (mild atrophy on the right) - mild-to-moderate atrophy of the left frontal lobe and moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: precentral gyrus medial segment (mild atrophy on the left and mild-to-moderate atrophy on the right), sup. frontal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), precentral gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), supplementary motor cortex (mild atrophy both left/right), middle frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), lateral orbital gyrus (mild atrophy on the left and normal on the right), gyrus rectus (mild atrophy on the left and normal on the right), medial frontal cortex (mild atrophy on the left) and sup. frontal gyrus medial segment (normal on the left and mild atrophy on the right) - parietal lobe appears within normal limits without apparent atrophy - limbic cortex demonstrates a healthy morphology without signs of atrophy For the ventricles: - mild enlargement of the 4th ventricle - mild enlargement of the left lateral ventricle and mild-to-moderate enlargement of the right lateral ventricle - moderate enlargement of the 3rd ventricle - mild-to-moderate enlargement of the external csf - moderate bilateral enlargement of the inf. lateral ventricle For the subcortical structures: - hippocampus appears within normal limits without apparent atrophy - the basal forebrain shows no notable changes suggestive of atrophy - mild atrophy of the right accumbens; normal-to-mild atrophy of the left accumbens - ventral dc demonstrates a healthy morphology without signs of atrophy - mild bilateral atrophy of the thalamus - no evident atrophy or tissue thinning seen in the pallidum - amygdala appears within normal limits without apparent atrophy - mild bilateral atrophy of the caudate - putamen demonstrates a healthy morphology without signs of atrophy
PNFA
ADNI_114_S_6429_MR_Accelerated_Sagittal_MPRAGE__br_raw_20180912114535504_109_S726434_I1047619
On a T1-weighted brain MRI we observed: For the subcortical structures: - no evident atrophy or tissue thinning seen in the hippocampus - amygdala appears within normal limits without apparent atrophy - no observable atrophic changes in the basal forebrain - thalamus demonstrates a healthy morphology without signs of atrophy - pallidum maintains a normal appearance with no observable atrophic features - accumbens appears within normal limits without apparent atrophy - no clear atrophic alterations are visible in the ventral dc - no clear atrophic alterations are visible in the putamen - no appreciable degenerative or atrophic changes observed in the caudate For the ventricles: - the lateral ventricle shows no notable changes suggestive of enlargement - inf. lateral ventricle appears within normal size limits with no apparent enlargement - 3rd ventricle maintains its expected proportions without signs of enlargement - external csf appears within normal size limits with no apparent enlargement - mild enlargement of the 4th ventricle For the cerebral cortex: - mild atrophy of the right occipital lobe; normal-to-mild atrophy of the left occipital lobe; focal volume loss observed in the following subregions: cuneus (mild atrophy on the left and normal-to-mild atrophy on the right) - frontal lobe appears preserved, with no observable tissue loss - mild atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: middle cingulate gyrus (mild-to-moderate atrophy on the right) - insular cortex demonstrates a healthy morphology without signs of atrophy - temporal lobe appears within normal limits without apparent atrophy - moderate atrophy of the left parietal lobe and mild-to-moderate atrophy of the right parietal lobe; focal volume loss observed in the following subregions: postcentral gyrus (mild atrophy both left/right), precuneus (mild atrophy both left/right), angular gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), postcentral gyrus medial segment (normal-to-mild atrophy on the left and mild atrophy on the right) and supramarginal gyrus (normal on the left and mild atrophy on the right)
CN
ADNI_035_S_0555_MR_Accelerated_Sagittal_MPRAGE__br_raw_20180215140443663_131_S659816_I964899
On a T1-weighted brain MRI we observed: For the ventricles: - mild enlargement of the left lateral ventricle and moderate enlargement of the right lateral ventricle - mild-to-moderate enlargement of the left inf. lateral ventricle and severe enlargement of the right inf. lateral ventricle - mild-to-moderate enlargement of the 4th ventricle - mild enlargement of the 3rd ventricle - no observable enlargement of the external csf For the subcortical structures: - mild-to-moderate bilateral atrophy of the putamen - mild atrophy of the right hippocampus - no observable atrophic changes in the thalamus - mild bilateral atrophy of the ventral dc - accumbens appears preserved, with no observable tissue loss - mild atrophy of the left caudate and mild-to-moderate atrophy of the right caudate - mild atrophy of the left basal forebrain; normal-to-mild atrophy of the right basal forebrain - mild bilateral atrophy of the pallidum - amygdala appears preserved, with no observable tissue loss For the cerebral cortex: - no evident atrophy or tissue thinning seen in the frontal lobe - mild atrophy of the right occipital lobe; the left occipital lobe is normal; focal volume loss observed in the following subregions: middle occipital gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right) and occipital pole (mild atrophy on the right) - the insular cortex shows no notable changes suggestive of atrophy - mild-to-moderate atrophy of the right temporal lobe; the left temporal lobe is normal; focal volume loss observed in the following subregions: fusiform gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), middle temporal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and sup. temporal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) - no clear atrophic alterations are visible in the limbic cortex - mild bilateral atrophy of the parietal lobe; focal volume loss observed in the following subregions: precuneus (mild-to-moderate atrophy both left/right), angular gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right) and postcentral gyrus (mild-to-moderate atrophy on the left and normal on the right)
AD
FTLD_203656054_03455_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450768
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild atrophy of the right accumbens; the left accumbens is normal - basal forebrain maintains a normal appearance with no observable atrophic features - severe bilateral atrophy of the amygdala - caudate appears preserved, with no observable tissue loss - putamen demonstrates a healthy morphology without signs of atrophy - the pallidum shows no notable changes suggestive of atrophy - mild-to-moderate atrophy of the left hippocampus - moderate-to-severe atrophy of the right hippocampus - no evident atrophy or tissue thinning seen in the ventral dc - mild bilateral atrophy of the thalamus For the ventricles: - no clear enlargement or abnormal growth seen in the 4th ventricle - mild enlargement of the external csf - mild enlargement of the 3rd ventricle - mild enlargement of the right lateral ventricle; normal-to-mild enlargement of the left lateral ventricle - severe bilateral enlargement of the inf. lateral ventricle For the cerebral cortex: - no appreciable degenerative or atrophic changes observed in the frontal lobe - no observable atrophic changes in the parietal lobe - moderate atrophy of the left insular cortex and moderate-to-severe atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and moderate-to-severe atrophy on the right), posterior insula (mild atrophy on the left and mild-to-moderate atrophy on the right), parietal operculum (mild atrophy both left/right) and frontal operculum (normal-to-mild atrophy on the left and mild atrophy on the right) - moderate-to-severe atrophy of the left temporal lobe and severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate atrophy on the left and moderate-to-severe atrophy on the right), middle temporal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), inf. temporal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), planum temporale (mild atrophy both left/right), sup. temporal gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), transverse temporal gyrus (mild atrophy both left/right), fusiform gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right) and planum polare (normal-to-mild atrophy on the left and mild atrophy on the right) - occipital lobe demonstrates a healthy morphology without signs of atrophy - no findings suggestive of atrophy are seen in the limbic cortex
SV
FTLD_203437946_02643_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178155
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild-to-moderate atrophy of the left pallidum and mild atrophy of the right pallidum - no clear atrophic alterations are visible in the hippocampus - mild atrophy of the left caudate; normal-to-mild atrophy of the right caudate - ventral dc maintains a normal appearance with no observable atrophic features - no evident atrophy or tissue thinning seen in the accumbens - basal forebrain appears within normal limits without apparent atrophy - mild bilateral atrophy of the amygdala - mild atrophy of the left thalamus; normal-to-mild atrophy of the right thalamus - mild-to-moderate atrophy of the left putamen and mild atrophy of the right putamen For the ventricles: - no observable enlargement of the 4th ventricle - mild enlargement of the 3rd ventricle - mild-to-moderate enlargement of the left lateral ventricle and mild enlargement of the right lateral ventricle - no evident size increase noted in the inf. lateral ventricle - moderate enlargement of the external csf For the cerebral cortex: - moderate atrophy of the left frontal lobe and mild-to-moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: precentral gyrus (moderate-to-severe atrophy on the left and moderate atrophy on the right), middle frontal gyrus (moderate atrophy on the left and normal on the right), opercular inf. frontal gyrus (mild atrophy both left/right), sup. frontal gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), sup. frontal gyrus medial segment (mild atrophy on the left and normal-to-mild atrophy on the right), precentral gyrus medial segment (mild atrophy on the left) and supplementary motor cortex (normal on the left and mild atrophy on the right) - mild bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: fusiform gyrus (mild-to-moderate atrophy on the left and normal on the right) and temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right) - no appreciable degenerative or atrophic changes observed in the occipital lobe - mild-to-moderate atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: central operculum (mild atrophy both left/right) and posterior insula (mild atrophy on the left and normal on the right) - mild atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the right) - mild-to-moderate atrophy of the left parietal lobe and mild atrophy of the right parietal lobe; focal volume loss observed in the following subregions: angular gyrus (mild atrophy both left/right) and postcentral gyrus (mild atrophy on the left and normal-to-mild atrophy on the right)
PNFA
ADNI_029_S_4585_MR_IR-SPGR_w_acceleration_br_raw_20120419104545328_189_S147706_I298523
On a T1-weighted brain MRI we observed: For the ventricles: - no observable enlargement of the inf. lateral ventricle - no clear enlargement or abnormal growth seen in the 3rd ventricle - external csf maintains its expected proportions without signs of enlargement - lateral ventricle maintains its expected proportions without signs of enlargement - 4th ventricle maintains its expected proportions without signs of enlargement For the cerebral cortex: - temporal lobe maintains a normal appearance with no observable atrophic features - no observable atrophic changes in the insular cortex - no clear atrophic alterations are visible in the parietal lobe - occipital lobe appears within normal limits without apparent atrophy - frontal lobe demonstrates a healthy morphology without signs of atrophy - limbic cortex appears within normal limits without apparent atrophy For the subcortical structures: - no evident atrophy or tissue thinning seen in the caudate - mild atrophy of the right ventral dc; the left ventral dc is normal - no findings suggestive of atrophy are seen in the amygdala - no findings suggestive of atrophy are seen in the accumbens - mild atrophy of the left basal forebrain; the right basal forebrain is normal - mild atrophy of the left pallidum; normal-to-mild atrophy of the right pallidum - the putamen shows no notable changes suggestive of atrophy - no findings suggestive of atrophy are seen in the hippocampus - the thalamus shows no notable changes suggestive of atrophy
CN
FTLD_203686328_03828_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10451178
On a T1-weighted brain MRI we observed: For the subcortical structures: - no findings suggestive of atrophy are seen in the putamen - the left hippocampus volume is borderline low - the left hippocampus volume is borderline low - no evident atrophy or tissue thinning seen in the caudate - amygdala appears within normal limits without apparent atrophy - thalamus demonstrates a healthy morphology without signs of atrophy - mild atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens - ventral dc appears preserved, with no observable tissue loss - mild bilateral atrophy of the pallidum - basal forebrain demonstrates a healthy morphology without signs of atrophy For the cerebral cortex: - no evident atrophy or tissue thinning seen in the temporal lobe - no appreciable degenerative or atrophic changes observed in the limbic cortex - no findings suggestive of atrophy are seen in the frontal lobe - no evident atrophy or tissue thinning seen in the parietal lobe - no appreciable degenerative or atrophic changes observed in the occipital lobe - no evident atrophy or tissue thinning seen in the insular cortex For the ventricles: - 4th ventricle appears within normal size limits with no apparent enlargement - no clear enlargement or abnormal growth seen in the external csf - mild bilateral enlargement of the inf. lateral ventricle - no findings suggestive of enlargement are seen in the lateral ventricle - 3rd ventricle maintains a typical volume without observable enlargement
BV
ADNI_016_S_5032_MR_Accelerated_SAG_IR-SPGR__br_raw_20121130134021740_63_S175940_I348593
On a T1-weighted brain MRI we observed: For the ventricles: - 4th ventricle maintains its expected proportions without signs of enlargement - no appreciable enlargement noted in the external csf - no findings suggestive of enlargement are seen in the inf. lateral ventricle - no observable enlargement of the 3rd ventricle - no findings suggestive of enlargement are seen in the lateral ventricle For the cerebral cortex: - the frontal lobe shows no notable changes suggestive of atrophy - parietal lobe appears within normal limits without apparent atrophy - insular cortex appears preserved, with no observable tissue loss - occipital lobe demonstrates a healthy morphology without signs of atrophy - no clear atrophic alterations are visible in the limbic cortex - no appreciable degenerative or atrophic changes observed in the temporal lobe For the subcortical structures: - mild atrophy of the left amygdala and moderate atrophy of the right amygdala - the putamen shows no notable changes suggestive of atrophy - no findings suggestive of atrophy are seen in the basal forebrain - mild bilateral atrophy of the accumbens - ventral dc appears preserved, with no observable tissue loss - no observable atrophic changes in the pallidum - no observable atrophic changes in the caudate - no findings suggestive of atrophy are seen in the hippocampus - thalamus appears within normal limits without apparent atrophy
AD
ADNI_941_S_6058_MR_Accelerated_Sagittal_MPRAGE__br_raw_20170810081036981_159_S592771_I884964
On a T1-weighted brain MRI we observed: For the subcortical structures: - putamen maintains a normal appearance with no observable atrophic features - no evident atrophy or tissue thinning seen in the amygdala - thalamus maintains a normal appearance with no observable atrophic features - the caudate shows no notable changes suggestive of atrophy - pallidum appears within normal limits without apparent atrophy - ventral dc appears preserved, with no observable tissue loss - no evident atrophy or tissue thinning seen in the basal forebrain - no evident atrophy or tissue thinning seen in the accumbens - no appreciable degenerative or atrophic changes observed in the hippocampus For the cerebral cortex: - no observable atrophic changes in the occipital lobe - frontal lobe appears preserved, with no observable tissue loss - parietal lobe maintains a normal appearance with no observable atrophic features - no appreciable degenerative or atrophic changes observed in the insular cortex - no observable atrophic changes in the temporal lobe - no evident atrophy or tissue thinning seen in the limbic cortex For the ventricles: - no clear enlargement or abnormal growth seen in the external csf - no appreciable enlargement noted in the inf. lateral ventricle - no observable enlargement of the 3rd ventricle - no evident size increase noted in the 4th ventricle - no evident size increase noted in the lateral ventricle
CN
FTLD_203440685_03584_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10450955
On a T1-weighted brain MRI we observed: For the ventricles: - no observable enlargement of the 4th ventricle - mild-to-moderate enlargement of the external csf - inf. lateral ventricle appears to be of normal dimensions, with no observable increase in size - 3rd ventricle appears within normal size limits with no apparent enlargement - no evident size increase noted in the lateral ventricle For the cerebral cortex: - parietal lobe demonstrates a healthy morphology without signs of atrophy - no appreciable degenerative or atrophic changes observed in the temporal lobe - the insular cortex shows no notable changes suggestive of atrophy - mild atrophy of the left frontal lobe and mild-to-moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: precentral gyrus (mild-to-moderate atrophy on the left and moderate atrophy on the right), medial frontal cortex (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), sup. frontal gyrus (mild atrophy both left/right), opercular inf. frontal gyrus (normal on the left and mild atrophy on the right) and precentral gyrus medial segment (normal on the left and mild atrophy on the right) - no evident atrophy or tissue thinning seen in the limbic cortex - no clear atrophic alterations are visible in the occipital lobe For the subcortical structures: - hippocampus appears within normal limits without apparent atrophy - mild-to-moderate bilateral atrophy of the accumbens - mild atrophy of the left ventral dc and mild-to-moderate atrophy of the right ventral dc - mild atrophy of the right caudate; normal-to-mild atrophy of the left caudate - mild bilateral atrophy of the putamen - amygdala maintains a normal appearance with no observable atrophic features - mild atrophy of the left pallidum and mild-to-moderate atrophy of the right pallidum - no findings suggestive of atrophy are seen in the basal forebrain - mild atrophy of the right thalamus; the left thalamus is normal
PNFA
FTLD_203432376_01673_MR_Sagittal_MP-Rage_br_raw_20230206145827122_I10181308
On a T1-weighted brain MRI we observed: For the subcortical structures: - no appreciable degenerative or atrophic changes observed in the thalamus - mild atrophy of the right caudate; normal-to-mild atrophy of the left caudate - mild-to-moderate atrophy of the left putamen and moderate atrophy of the right putamen - no appreciable degenerative or atrophic changes observed in the ventral dc - no observable atrophic changes in the basal forebrain - mild atrophy of the left pallidum and mild-to-moderate atrophy of the right pallidum - moderate bilateral atrophy of the amygdala - mild-to-moderate atrophy of the left accumbens and moderate atrophy of the right accumbens - hippocampus demonstrates a healthy morphology without signs of atrophy For the ventricles: - moderate-to-severe enlargement of the external csf - mild enlargement of the 4th ventricle - the inf. lateral ventricle shows no notable changes suggestive of enlargement - lateral ventricle appears to be of normal dimensions, with no observable increase in size - no appreciable enlargement noted in the 3rd ventricle For the cerebral cortex: - limbic cortex appears preserved, with no observable tissue loss - mild atrophy of the left insular cortex and moderate atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and mild-to-moderate atrophy on the right), parietal operculum (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right) and central operculum (mild atrophy on the right) - parietal lobe demonstrates a healthy morphology without signs of atrophy - mild atrophy of the right temporal lobe; the left temporal lobe is normal; focal volume loss observed in the following subregions: fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. temporal gyrus (normal on the left and mild-to-moderate atrophy on the right), transverse temporal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right) and planum temporale (normal on the left and mild atrophy on the right) - mild atrophy of the left frontal lobe and moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: frontal pole (mild atrophy on the left and moderate atrophy on the right), middle frontal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), sup. frontal gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), medial frontal cortex (normal on the left and mild atrophy on the right), anterior orbital gyrus (normal on the left and mild atrophy on the right) and precentral gyrus (normal on the left and mild atrophy on the right) - mild atrophy of the right occipital lobe; normal-to-mild atrophy of the left occipital lobe; focal volume loss observed in the following subregions: inf. occipital gyrus (normal on the left and mild-to-moderate atrophy on the right)
PNFA
ADNI_073_S_5023_MR_MPRAGE_br_raw_20131009133645228_136_S203499_I393941
On a T1-weighted brain MRI we observed: For the subcortical structures: - caudate appears preserved, with no observable tissue loss - no clear atrophic alterations are visible in the hippocampus - no clear atrophic alterations are visible in the basal forebrain - thalamus maintains a normal appearance with no observable atrophic features - no appreciable degenerative or atrophic changes observed in the amygdala - no observable atrophic changes in the ventral dc - accumbens demonstrates a healthy morphology without signs of atrophy - pallidum appears within normal limits without apparent atrophy - putamen maintains a normal appearance with no observable atrophic features For the cerebral cortex: - frontal lobe appears preserved, with no observable tissue loss - the temporal lobe shows no notable changes suggestive of atrophy - limbic cortex appears preserved, with no observable tissue loss - no evident atrophy or tissue thinning seen in the occipital lobe - no appreciable degenerative or atrophic changes observed in the insular cortex - parietal lobe appears within normal limits without apparent atrophy For the ventricles: - external csf appears to be of normal dimensions, with no observable increase in size - no clear enlargement or abnormal growth seen in the lateral ventricle - no appreciable enlargement noted in the inf. lateral ventricle - 3rd ventricle maintains a typical volume without observable enlargement - 4th ventricle appears to be of normal dimensions, with no observable increase in size
CN
FTLD_203708389_02980_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450121
On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild atrophy of the left temporal lobe and mild-to-moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (mild atrophy on the left and moderate atrophy on the right) and inf. temporal gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right) - parietal lobe maintains a normal appearance with no observable atrophic features - mild-to-moderate atrophy of the right frontal lobe; the left frontal lobe is normal; focal volume loss observed in the following subregions: gyrus rectus (mild atrophy on the left and moderate atrophy on the right), medial orbital gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), sup. frontal gyrus medial segment (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), triangular inf. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), medial frontal cortex (normal on the left and mild-to-moderate atrophy on the right), posterior orbital gyrus (normal on the left and mild atrophy on the right), frontal pole (normal on the left and mild atrophy on the right), orbital inf. frontal gyrus (normal on the left and mild atrophy on the right) and lateral orbital gyrus (normal on the left and mild atrophy on the right) - mild atrophy of the left limbic cortex and moderate atrophy of the right limbic cortex; focal volume loss observed in the following subregions: parahippocampal gyrus (moderate-to-severe atrophy both left/right), entorhinal area (mild atrophy on the left and moderate atrophy on the right) and anterior cingulate gyrus (normal on the left and mild-to-moderate atrophy on the right) - mild atrophy of the left insular cortex and moderate atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and severe atrophy on the right) and posterior insula (mild atrophy on the left and mild-to-moderate atrophy on the right) - no findings suggestive of atrophy are seen in the occipital lobe For the subcortical structures: - no clear atrophic alterations are visible in the basal forebrain - severe bilateral atrophy of the amygdala - moderate-to-severe atrophy of the left accumbens and severe atrophy of the right accumbens - severe atrophy of the left hippocampus - severe atrophy of the right hippocampus - moderate-to-severe atrophy of the left caudate and severe atrophy of the right caudate - mild-to-moderate bilateral atrophy of the ventral dc - mild-to-moderate atrophy of the left thalamus and moderate-to-severe atrophy of the right thalamus - moderate-to-severe atrophy of the left putamen and severe atrophy of the right putamen - moderate-to-severe atrophy of the left pallidum and severe atrophy of the right pallidum For the ventricles: - mild-to-moderate enlargement of the external csf - mild-to-moderate bilateral enlargement of the lateral ventricle - mild enlargement of the 3rd ventricle - severe bilateral enlargement of the inf. lateral ventricle - the 4th ventricle shows no notable changes suggestive of enlargement
BV
FTLD_203519649_02941_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177147
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no appreciable degenerative or atrophic changes observed in the parietal lobe - no appreciable degenerative or atrophic changes observed in the insular cortex - no clear atrophic alterations are visible in the limbic cortex - occipital lobe demonstrates a healthy morphology without signs of atrophy - temporal lobe appears preserved, with no observable tissue loss - frontal lobe appears preserved, with no observable tissue loss For the subcortical structures: - no evident atrophy or tissue thinning seen in the putamen - mild atrophy of the right hippocampus - basal forebrain appears within normal limits without apparent atrophy - moderate atrophy of the left accumbens and mild atrophy of the right accumbens - no findings suggestive of atrophy are seen in the thalamus - no appreciable degenerative or atrophic changes observed in the ventral dc - mild bilateral atrophy of the pallidum - caudate appears preserved, with no observable tissue loss - mild bilateral atrophy of the amygdala For the ventricles: - no clear enlargement or abnormal growth seen in the 4th ventricle - mild enlargement of the external csf - mild enlargement of the 3rd ventricle - lateral ventricle maintains a typical volume without observable enlargement - inf. lateral ventricle maintains its expected proportions without signs of enlargement
BV
ADNI_068_S_0473_MR_MPR____N3__Scaled_Br_20090402095548096_S13925_I140334
On a T1-weighted brain MRI we observed: For the cerebral cortex: - occipital lobe demonstrates a healthy morphology without signs of atrophy - mild atrophy of the left parietal lobe; the right parietal lobe is normal; focal volume loss observed in the following subregions: sup. parietal lobule (mild atrophy on the left and normal on the right) and postcentral gyrus medial segment (mild atrophy on the right) - frontal lobe appears within normal limits without apparent atrophy - insular cortex demonstrates a healthy morphology without signs of atrophy - temporal lobe appears within normal limits without apparent atrophy - no clear atrophic alterations are visible in the limbic cortex For the subcortical structures: - pallidum maintains a normal appearance with no observable atrophic features - mild bilateral atrophy of the ventral dc - mild atrophy of the left basal forebrain; normal-to-mild atrophy of the right basal forebrain - no observable atrophic changes in the amygdala - no clear atrophic alterations are visible in the thalamus - the accumbens shows no notable changes suggestive of atrophy - putamen appears within normal limits without apparent atrophy - no observable atrophic changes in the caudate - no evident atrophy or tissue thinning seen in the hippocampus For the ventricles: - 4th ventricle appears to be of normal dimensions, with no observable increase in size - lateral ventricle maintains a typical volume without observable enlargement - no appreciable enlargement noted in the external csf - no findings suggestive of enlargement are seen in the 3rd ventricle - no appreciable enlargement noted in the inf. lateral ventricle
CN
ADNI_052_S_1250_MR_MPR__GradWarp__B1_Correction__N3__Scaled_Br_20070727104806153_S25829_I62240
On a T1-weighted brain MRI we observed: For the ventricles: - the 4th ventricle shows no notable changes suggestive of enlargement - the lateral ventricle shows no notable changes suggestive of enlargement - 3rd ventricle appears to be of normal dimensions, with no observable increase in size - mild enlargement of the right inf. lateral ventricle; the left inf. lateral ventricle is normal - external csf maintains its expected proportions without signs of enlargement For the cerebral cortex: - limbic cortex appears within normal limits without apparent atrophy - no clear atrophic alterations are visible in the insular cortex - no observable atrophic changes in the parietal lobe - no appreciable degenerative or atrophic changes observed in the temporal lobe - no findings suggestive of atrophy are seen in the occipital lobe - no findings suggestive of atrophy are seen in the frontal lobe For the subcortical structures: - hippocampus demonstrates a healthy morphology without signs of atrophy - accumbens demonstrates a healthy morphology without signs of atrophy - basal forebrain appears within normal limits without apparent atrophy - caudate appears within normal limits without apparent atrophy - amygdala demonstrates a healthy morphology without signs of atrophy - ventral dc demonstrates a healthy morphology without signs of atrophy - no clear atrophic alterations are visible in the thalamus - no clear atrophic alterations are visible in the pallidum - the putamen shows no notable changes suggestive of atrophy
CN
FTLD_203723261_03162_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10177101
On a T1-weighted brain MRI we observed: For the ventricles: - 3rd ventricle maintains a typical volume without observable enlargement - 4th ventricle maintains a typical volume without observable enlargement - severe bilateral enlargement of the inf. lateral ventricle - severe enlargement of the left lateral ventricle and mild-to-moderate enlargement of the right lateral ventricle - mild-to-moderate enlargement of the external csf For the cerebral cortex: - no appreciable degenerative or atrophic changes observed in the parietal lobe - severe atrophy of the left temporal lobe and mild-to-moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy on the left and moderate atrophy on the right), inf. temporal gyrus (moderate-to-severe atrophy on the left and mild atrophy on the right), middle temporal gyrus (moderate-to-severe atrophy on the left and normal-to-mild atrophy on the right), fusiform gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), planum polare (mild atrophy both left/right), sup. temporal gyrus (mild-to-moderate atrophy on the left) and planum temporale (mild atrophy on the left) - mild bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: entorhinal area (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right) and parahippocampal gyrus (mild-to-moderate atrophy on the left and normal on the right) - mild atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: gyrus rectus (mild-to-moderate atrophy on the left and normal on the right), triangular inf. frontal gyrus (mild atrophy on the right), medial frontal cortex (mild atrophy on the left) and anterior orbital gyrus (mild atrophy on the left) - no clear atrophic alterations are visible in the occipital lobe - mild-to-moderate atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), posterior insula (moderate atrophy both left/right) and central operculum (mild atrophy on the left) For the subcortical structures: - basal forebrain appears within normal limits without apparent atrophy - severe bilateral atrophy of the amygdala - ventral dc appears preserved, with no observable tissue loss - moderate-to-severe atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens - moderate-to-severe atrophy of the left putamen and mild-to-moderate atrophy of the right putamen - mild atrophy of the left thalamus; the right thalamus is normal - moderate atrophy of the left pallidum and mild-to-moderate atrophy of the right pallidum - moderate-to-severe atrophy of the left hippocampus - moderate-to-severe atrophy of the right hippocampus - moderate atrophy of the left caudate and mild atrophy of the right caudate
SV
ADNI_100_S_0190_MR_MPR____N3__Scaled_Br_20061213164423765_S13689_I33109
On a T1-weighted brain MRI we observed: For the ventricles: - 4th ventricle maintains its expected proportions without signs of enlargement - no clear enlargement or abnormal growth seen in the external csf - mild-to-moderate enlargement of the left lateral ventricle and moderate enlargement of the right lateral ventricle - 3rd ventricle appears to be of normal dimensions, with no observable increase in size - moderate enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle For the subcortical structures: - mild bilateral atrophy of the ventral dc - mild-to-moderate bilateral atrophy of the caudate - moderate atrophy of the left pallidum and mild-to-moderate atrophy of the right pallidum - mild-to-moderate bilateral atrophy of the thalamus - mild-to-moderate bilateral atrophy of the accumbens - mild-to-moderate bilateral atrophy of the putamen - severe bilateral atrophy of the amygdala - no evident atrophy or tissue thinning seen in the basal forebrain - mild-to-moderate atrophy of the left hippocampus - moderate atrophy of the right hippocampus For the cerebral cortex: - the insular cortex shows no notable changes suggestive of atrophy - moderate atrophy of the left temporal lobe and mild-to-moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (mild-to-moderate atrophy both left/right), inf. temporal gyrus (mild atrophy both left/right), middle temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. temporal gyrus (mild-to-moderate atrophy on the left and normal on the right), planum polare (mild atrophy on the left) and planum temporale (mild atrophy on the left and normal on the right) - mild atrophy of the right limbic cortex; normal-to-mild atrophy of the left limbic cortex; focal volume loss observed in the following subregions: entorhinal area (moderate atrophy on the left and mild-to-moderate atrophy on the right) and parahippocampal gyrus (moderate atrophy on the left and mild atrophy on the right) - no findings suggestive of atrophy are seen in the frontal lobe - no appreciable degenerative or atrophic changes observed in the occipital lobe - the parietal lobe shows no notable changes suggestive of atrophy
AD
ADNI_011_S_0005_MR_MPR-R__GradWarp__B1_Correction__N3__Scaled_Br_20061208112603927_S9136_I32246
On a T1-weighted brain MRI we observed: For the subcortical structures: - basal forebrain demonstrates a healthy morphology without signs of atrophy - putamen appears preserved, with no observable tissue loss - the caudate shows no notable changes suggestive of atrophy - mild-to-moderate atrophy of the left hippocampus - no findings suggestive of atrophy are seen in the pallidum - moderate atrophy of the left amygdala and mild atrophy of the right amygdala - ventral dc demonstrates a healthy morphology without signs of atrophy - no evident atrophy or tissue thinning seen in the accumbens - thalamus appears within normal limits without apparent atrophy For the ventricles: - no appreciable enlargement noted in the inf. lateral ventricle - the 3rd ventricle shows no notable changes suggestive of enlargement - no findings suggestive of enlargement are seen in the external csf - the lateral ventricle shows no notable changes suggestive of enlargement - no evident size increase noted in the 4th ventricle For the cerebral cortex: - mild atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: sup. temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) - no evident atrophy or tissue thinning seen in the insular cortex - no appreciable degenerative or atrophic changes observed in the occipital lobe - the frontal lobe shows no notable changes suggestive of atrophy - the parietal lobe shows no notable changes suggestive of atrophy - no clear atrophic alterations are visible in the limbic cortex
CN
ADNI_002_S_6009_MR_Accelerated_Sagittal_MPRAGE__br_raw_20170418133703199_1_S555304_I840235
On a T1-weighted brain MRI we observed: For the subcortical structures: - no appreciable degenerative or atrophic changes observed in the putamen - no findings suggestive of atrophy are seen in the accumbens - mild atrophy of the right basal forebrain; the left basal forebrain is normal - no clear atrophic alterations are visible in the amygdala - no evident atrophy or tissue thinning seen in the pallidum - thalamus maintains a normal appearance with no observable atrophic features - ventral dc appears within normal limits without apparent atrophy - no evident atrophy or tissue thinning seen in the caudate - no appreciable degenerative or atrophic changes observed in the hippocampus For the ventricles: - no observable enlargement of the 3rd ventricle - no appreciable enlargement noted in the 4th ventricle - external csf appears to be of normal dimensions, with no observable increase in size - lateral ventricle maintains its expected proportions without signs of enlargement - no clear enlargement or abnormal growth seen in the inf. lateral ventricle For the cerebral cortex: - no findings suggestive of atrophy are seen in the frontal lobe - occipital lobe appears preserved, with no observable tissue loss - no observable atrophic changes in the temporal lobe - no evident atrophy or tissue thinning seen in the parietal lobe - no findings suggestive of atrophy are seen in the limbic cortex - no evident atrophy or tissue thinning seen in the insular cortex
CN
ADNI_141_S_0726_MR_MPR__GradWarp__B1_Correction__N3__Scaled_Br_20080302105053142_S18354_I94824
On a T1-weighted brain MRI we observed: For the ventricles: - no findings suggestive of enlargement are seen in the lateral ventricle - no evident size increase noted in the external csf - mild enlargement of the right inf. lateral ventricle; the left inf. lateral ventricle is normal - the 4th ventricle shows no notable changes suggestive of enlargement - no evident size increase noted in the 3rd ventricle For the cerebral cortex: - limbic cortex demonstrates a healthy morphology without signs of atrophy - the temporal lobe shows no notable changes suggestive of atrophy - no clear atrophic alterations are visible in the frontal lobe - mild atrophy of the left parietal lobe; the right parietal lobe is normal; focal volume loss observed in the following subregions: postcentral gyrus (mild atrophy both left/right) and angular gyrus (mild-to-moderate atrophy on the left) - the occipital lobe shows no notable changes suggestive of atrophy - no findings suggestive of atrophy are seen in the insular cortex For the subcortical structures: - putamen demonstrates a healthy morphology without signs of atrophy - no clear atrophic alterations are visible in the ventral dc - the caudate shows no notable changes suggestive of atrophy - no findings suggestive of atrophy are seen in the amygdala - the basal forebrain shows no notable changes suggestive of atrophy - thalamus demonstrates a healthy morphology without signs of atrophy - no clear atrophic alterations are visible in the accumbens - hippocampus appears within normal limits without apparent atrophy - the pallidum shows no notable changes suggestive of atrophy
CN
FTLD_203320313_03312_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10176943
On a T1-weighted brain MRI we observed: For the ventricles: - mild enlargement of the left lateral ventricle and mild-to-moderate enlargement of the right lateral ventricle - mild enlargement of the 3rd ventricle - no evident size increase noted in the 4th ventricle - moderate-to-severe bilateral enlargement of the inf. lateral ventricle - external csf maintains a typical volume without observable enlargement For the subcortical structures: - the pallidum shows no notable changes suggestive of atrophy - mild atrophy of the left amygdala and mild-to-moderate atrophy of the right amygdala - basal forebrain maintains a normal appearance with no observable atrophic features - no appreciable degenerative or atrophic changes observed in the thalamus - no clear atrophic alterations are visible in the putamen - the left hippocampus volume is borderline low - mild atrophy of the right hippocampus - mild atrophy of the left accumbens; the right accumbens is normal - the ventral dc shows no notable changes suggestive of atrophy - no clear atrophic alterations are visible in the caudate For the cerebral cortex: - no evident atrophy or tissue thinning seen in the parietal lobe - mild-to-moderate atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: inf. temporal gyrus (mild-to-moderate atrophy on the left and normal on the right), temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right) and middle temporal gyrus (normal on the left and mild atrophy on the right) - mild atrophy of the left occipital lobe; the right occipital lobe is normal; focal volume loss observed in the following subregions: middle occipital gyrus (mild atrophy on the left), sup. occipital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), cuneus (mild atrophy on the left and normal on the right), occipital fusiform gyrus (mild atrophy on the left) and occipital pole (mild atrophy on the right) - mild atrophy of the left frontal lobe; normal-to-mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: gyrus rectus (mild atrophy both left/right), lateral orbital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), precentral gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), frontal pole (normal on the left and mild atrophy on the right), medial frontal cortex (normal on the left and mild atrophy on the right), sup. frontal gyrus (mild atrophy on the left and normal on the right), medial orbital gyrus (mild atrophy on the right) and posterior orbital gyrus (mild atrophy on the left and normal on the right) - no observable atrophic changes in the insular cortex - mild bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: entorhinal area (mild atrophy both left/right), anterior cingulate gyrus (mild atrophy on the left and normal on the right) and posterior cingulate gyrus (normal on the left and mild atrophy on the right)
SV
FTLD_203447962_03264_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10177413
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild atrophy of the left pallidum and moderate atrophy of the right pallidum - mild-to-moderate atrophy of the left caudate and mild atrophy of the right caudate - mild atrophy of the left hippocampus - mild-to-moderate atrophy of the right hippocampus - severe bilateral atrophy of the amygdala - thalamus appears preserved, with no observable tissue loss - no observable atrophic changes in the basal forebrain - mild atrophy of the left putamen and severe atrophy of the right putamen - ventral dc demonstrates a healthy morphology without signs of atrophy - moderate-to-severe atrophy of the left accumbens and severe atrophy of the right accumbens For the cerebral cortex: - mild-to-moderate bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: entorhinal area (moderate atrophy both left/right), anterior cingulate gyrus (mild atrophy both left/right) and parahippocampal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) - severe bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy both left/right), fusiform gyrus (mild-to-moderate atrophy on the left and moderate atrophy on the right), inf. temporal gyrus (mild-to-moderate atrophy on the left and moderate atrophy on the right), sup. temporal gyrus (mild atrophy on the left and moderate atrophy on the right) and middle temporal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right) - parietal lobe maintains a normal appearance with no observable atrophic features - no clear atrophic alterations are visible in the frontal lobe - mild atrophy of the left insular cortex and moderate atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and severe atrophy on the right) and posterior insula (mild atrophy on the left and mild-to-moderate atrophy on the right) - occipital lobe maintains a normal appearance with no observable atrophic features For the ventricles: - mild enlargement of the external csf - mild enlargement of the 3rd ventricle - severe bilateral enlargement of the inf. lateral ventricle - mild enlargement of the right lateral ventricle; the left lateral ventricle is normal - no evident size increase noted in the 4th ventricle
SV
ADNI_099_S_0492_MR_MPR__GradWarp__B1_Correction__N3__Scaled_Br_20070209170021020_S14944_I38770
On a T1-weighted brain MRI we observed: For the subcortical structures: - the pallidum shows no notable changes suggestive of atrophy - mild bilateral atrophy of the amygdala - thalamus demonstrates a healthy morphology without signs of atrophy - accumbens demonstrates a healthy morphology without signs of atrophy - mild atrophy of the left hippocampus - the left hippocampus volume is borderline low - no clear atrophic alterations are visible in the basal forebrain - no findings suggestive of atrophy are seen in the caudate - no findings suggestive of atrophy are seen in the ventral dc - no findings suggestive of atrophy are seen in the putamen For the ventricles: - no clear enlargement or abnormal growth seen in the lateral ventricle - no evident size increase noted in the 3rd ventricle - mild enlargement of the 4th ventricle - no clear enlargement or abnormal growth seen in the external csf - severe enlargement of the left inf. lateral ventricle and mild-to-moderate enlargement of the right inf. lateral ventricle For the cerebral cortex: - occipital lobe maintains a normal appearance with no observable atrophic features - parietal lobe demonstrates a healthy morphology without signs of atrophy - the insular cortex shows no notable changes suggestive of atrophy; focal volume loss observed in the following subregions: central operculum (mild atrophy both left/right) - mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (mild atrophy on the left and normal-to-mild atrophy on the right) and posterior cingulate gyrus (mild atrophy on the left and normal on the right) - no findings suggestive of atrophy are seen in the frontal lobe - moderate atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: fusiform gyrus (mild atrophy both left/right), middle temporal gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), planum polare (mild atrophy on the left and normal-to-mild atrophy on the right), temporal pole (normal-to-mild atrophy on the left and mild atrophy on the right) and inf. temporal gyrus (mild atrophy on the left)
AD
FTLD_203117063_03361_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10176826
On a T1-weighted brain MRI we observed: For the subcortical structures: - moderate atrophy of the left caudate and mild atrophy of the right caudate - severe atrophy of the left putamen and mild-to-moderate atrophy of the right putamen - mild-to-moderate atrophy of the left ventral dc; normal-to-mild atrophy of the right ventral dc - moderate atrophy of the left accumbens and mild atrophy of the right accumbens - moderate atrophy of the left pallidum; normal-to-mild atrophy of the right pallidum - moderate-to-severe atrophy of the left amygdala; normal-to-mild atrophy of the right amygdala - severe atrophy of the left thalamus; the right thalamus is normal - severe atrophy of the left hippocampus - moderate atrophy of the right hippocampus - no findings suggestive of atrophy are seen in the basal forebrain For the cerebral cortex: - mild-to-moderate atrophy of the left limbic cortex; normal-to-mild atrophy of the right limbic cortex; focal volume loss observed in the following subregions: parahippocampal gyrus (moderate atrophy on the left), anterior cingulate gyrus (mild atrophy both left/right) and middle cingulate gyrus (normal on the left and mild atrophy on the right) - no appreciable degenerative or atrophic changes observed in the occipital lobe - no clear atrophic alterations are visible in the parietal lobe - moderate atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: gyrus rectus (normal-to-mild atrophy on the left and mild atrophy on the right), opercular inf. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), sup. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), supplementary motor cortex (mild atrophy on the left), frontal pole (mild atrophy on the left and normal on the right), middle frontal gyrus (mild atrophy on the left and normal on the right), anterior orbital gyrus (mild atrophy on the left) and sup. frontal gyrus medial segment (mild atrophy on the left) - severe atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: sup. temporal gyrus (moderate atrophy on the left and mild atrophy on the right), middle temporal gyrus (moderate atrophy on the left and normal on the right), temporal pole (moderate atrophy on the left and normal on the right), planum temporale (mild atrophy both left/right), fusiform gyrus (mild-to-moderate atrophy on the left and normal on the right), planum polare (mild-to-moderate atrophy on the left and normal on the right), inf. temporal gyrus (mild-to-moderate atrophy on the left and normal on the right) and transverse temporal gyrus (mild atrophy on the left and normal on the right) - moderate-to-severe atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and normal-to-mild atrophy on the right), posterior insula (mild-to-moderate atrophy on the left and mild atrophy on the right), frontal operculum (mild atrophy both left/right), parietal operculum (mild atrophy on the left and normal-to-mild atrophy on the right) and central operculum (mild-to-moderate atrophy on the left) For the ventricles: - severe enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal - moderate enlargement of the 3rd ventricle - moderate-to-severe enlargement of the left lateral ventricle and mild enlargement of the right lateral ventricle - 4th ventricle maintains its expected proportions without signs of enlargement - moderate enlargement of the external csf
SV
FTLD_203175368_01867_MR_Sagittal_MP-Rage_br_raw_20230209093418458_I10183210
On a T1-weighted brain MRI we observed: For the ventricles: - moderate enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal - moderate enlargement of the external csf - mild enlargement of the left lateral ventricle; normal-to-mild enlargement of the right lateral ventricle - mild enlargement of the 4th ventricle - mild-to-moderate enlargement of the 3rd ventricle For the cerebral cortex: - moderate atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), entorhinal area (mild atrophy both left/right), posterior cingulate gyrus (mild atrophy on the left) and parahippocampal gyrus (mild atrophy on the left and normal on the right) - occipital lobe maintains a normal appearance with no observable atrophic features - mild-to-moderate atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: temporal pole (moderate atrophy on the left and normal-to-mild atrophy on the right), fusiform gyrus (mild atrophy both left/right) and middle temporal gyrus (mild atrophy on the left and normal on the right) - parietal lobe appears preserved, with no observable tissue loss - moderate atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (severe atrophy on the left and moderate atrophy on the right), frontal operculum (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), central operculum (mild atrophy on the left) and posterior insula (mild atrophy on the left and normal on the right) - severe atrophy of the left frontal lobe and mild-to-moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: gyrus rectus (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), frontal pole (mild-to-moderate atrophy both left/right), sup. frontal gyrus medial segment (mild-to-moderate atrophy on the left and mild atrophy on the right), triangular inf. frontal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), medial orbital gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), posterior orbital gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), middle frontal gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), sup. frontal gyrus (mild atrophy both left/right), orbital inf. frontal gyrus (mild-to-moderate atrophy on the left and normal on the right), medial frontal cortex (mild atrophy on the left and normal-to-mild atrophy on the right), lateral orbital gyrus (mild-to-moderate atrophy on the left), opercular inf. frontal gyrus (mild atrophy on the left and normal on the right) and anterior orbital gyrus (mild atrophy on the left) For the subcortical structures: - severe atrophy of the left amygdala and moderate atrophy of the right amygdala - basal forebrain appears preserved, with no observable tissue loss - pallidum maintains a normal appearance with no observable atrophic features - moderate-to-severe atrophy of the left putamen; the right putamen is normal - mild-to-moderate atrophy of the left caudate; the right caudate is normal - no clear atrophic alterations are visible in the ventral dc - mild atrophy of the left hippocampus - mild atrophy of the left thalamus; normal-to-mild atrophy of the right thalamus - moderate atrophy of the left accumbens and mild atrophy of the right accumbens
SV
FTLD_203117063_03361_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10176826
On a T1-weighted brain MRI we observed: For the subcortical structures: - moderate-to-severe atrophy of the left amygdala; normal-to-mild atrophy of the right amygdala - no observable atrophic changes in the basal forebrain - moderate atrophy of the left pallidum; normal-to-mild atrophy of the right pallidum - severe atrophy of the left thalamus; the right thalamus is normal - severe atrophy of the left putamen and mild-to-moderate atrophy of the right putamen - mild-to-moderate atrophy of the left ventral dc; normal-to-mild atrophy of the right ventral dc - moderate atrophy of the left caudate and mild atrophy of the right caudate - severe atrophy of the left hippocampus - moderate atrophy of the right hippocampus - moderate atrophy of the left accumbens and mild atrophy of the right accumbens For the ventricles: - moderate-to-severe enlargement of the left lateral ventricle and mild enlargement of the right lateral ventricle - moderate enlargement of the 3rd ventricle - no observable enlargement of the 4th ventricle - severe enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal - moderate enlargement of the external csf For the cerebral cortex: - mild-to-moderate atrophy of the left limbic cortex; normal-to-mild atrophy of the right limbic cortex; focal volume loss observed in the following subregions: parahippocampal gyrus (moderate atrophy on the left), anterior cingulate gyrus (mild atrophy both left/right) and middle cingulate gyrus (normal on the left and mild atrophy on the right) - moderate atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: gyrus rectus (normal-to-mild atrophy on the left and mild atrophy on the right), opercular inf. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), sup. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), supplementary motor cortex (mild atrophy on the left), frontal pole (mild atrophy on the left and normal on the right), middle frontal gyrus (mild atrophy on the left and normal on the right), anterior orbital gyrus (mild atrophy on the left) and sup. frontal gyrus medial segment (mild atrophy on the left) - no evident atrophy or tissue thinning seen in the parietal lobe - moderate-to-severe atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and normal-to-mild atrophy on the right), posterior insula (mild-to-moderate atrophy on the left and mild atrophy on the right), frontal operculum (mild atrophy both left/right), parietal operculum (mild atrophy on the left and normal-to-mild atrophy on the right) and central operculum (mild-to-moderate atrophy on the left) - severe atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: sup. temporal gyrus (moderate atrophy on the left and mild atrophy on the right), middle temporal gyrus (moderate atrophy on the left and normal on the right), temporal pole (moderate atrophy on the left and normal on the right), planum temporale (mild atrophy both left/right), fusiform gyrus (mild-to-moderate atrophy on the left and normal on the right), planum polare (mild-to-moderate atrophy on the left and normal on the right), inf. temporal gyrus (mild-to-moderate atrophy on the left and normal on the right) and transverse temporal gyrus (mild atrophy on the left and normal on the right) - no findings suggestive of atrophy are seen in the occipital lobe
SV
ADNI_114_S_0378_MR_MT1__GradWarp__N3m_Br_20120411164719630_S136142_I297046
On a T1-weighted brain MRI we observed: For the ventricles: - 4th ventricle appears to be of normal dimensions, with no observable increase in size - moderate-to-severe enlargement of the left inf. lateral ventricle and moderate enlargement of the right inf. lateral ventricle - mild-to-moderate enlargement of the 3rd ventricle - mild-to-moderate enlargement of the left lateral ventricle and mild enlargement of the right lateral ventricle - mild-to-moderate enlargement of the external csf For the cerebral cortex: - mild atrophy of the left occipital lobe and moderate-to-severe atrophy of the right occipital lobe; focal volume loss observed in the following subregions: inf. occipital gyrus (mild-to-moderate atrophy both left/right), cuneus (normal-to-mild atrophy on the left and mild atrophy on the right), lingual gyrus (normal on the left and mild-to-moderate atrophy on the right), middle occipital gyrus (mild atrophy on the right) and occipital pole (normal on the left and mild atrophy on the right) - no clear atrophic alterations are visible in the insular cortex - mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), posterior cingulate gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) and parahippocampal gyrus (normal on the left and mild atrophy on the right) - parietal lobe maintains a normal appearance with no observable atrophic features - moderate atrophy of the left temporal lobe and mild-to-moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: middle temporal gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), inf. temporal gyrus (mild atrophy both left/right), sup. temporal gyrus (mild atrophy on the left and normal on the right) and temporal pole (normal on the left and mild atrophy on the right) - no evident atrophy or tissue thinning seen in the frontal lobe For the subcortical structures: - mild atrophy of the left caudate; normal-to-mild atrophy of the right caudate - the putamen shows no notable changes suggestive of atrophy - the pallidum shows no notable changes suggestive of atrophy - no findings suggestive of atrophy are seen in the ventral dc - mild atrophy of the left thalamus; the right thalamus is normal - no observable atrophic changes in the basal forebrain - moderate bilateral atrophy of the amygdala - mild bilateral atrophy of the accumbens - mild-to-moderate atrophy of the left hippocampus - mild-to-moderate atrophy of the right hippocampus
AD
FTLD_203188503_03308_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10176913
On a T1-weighted brain MRI we observed: For the ventricles: - 3rd ventricle maintains a typical volume without observable enlargement - no observable enlargement of the external csf - the 4th ventricle shows no notable changes suggestive of enlargement - severe bilateral enlargement of the inf. lateral ventricle - mild-to-moderate enlargement of the left lateral ventricle and moderate enlargement of the right lateral ventricle For the subcortical structures: - moderate-to-severe atrophy of the left hippocampus - severe atrophy of the right hippocampus - mild atrophy of the right caudate; normal-to-mild atrophy of the left caudate - severe bilateral atrophy of the amygdala - mild bilateral atrophy of the putamen - mild-to-moderate bilateral atrophy of the accumbens - mild bilateral atrophy of the thalamus - ventral dc demonstrates a healthy morphology without signs of atrophy - basal forebrain appears within normal limits without apparent atrophy - mild bilateral atrophy of the pallidum For the cerebral cortex: - parietal lobe demonstrates a healthy morphology without signs of atrophy - mild-to-moderate atrophy of the left occipital lobe and mild atrophy of the right occipital lobe; focal volume loss observed in the following subregions: calcarine cortex (mild-to-moderate atrophy both left/right), inf. occipital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), occipital pole (mild atrophy on the left and normal-to-mild atrophy on the right) and cuneus (mild atrophy on the left and normal on the right) - frontal lobe demonstrates a healthy morphology without signs of atrophy - mild atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: parahippocampal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right) and entorhinal area (mild atrophy both left/right) - mild atrophy of the right insular cortex; normal-to-mild atrophy of the left insular cortex; focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), frontal operculum (mild atrophy both left/right) and posterior insula (normal-to-mild atrophy on the left and mild atrophy on the right) - mild atrophy of the left temporal lobe and mild-to-moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate atrophy both left/right), transverse temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and fusiform gyrus (normal on the left and mild atrophy on the right)
BV
ADNI_057_S_0934_MR_MPR__GradWarp__B1_Correction__N3__Scaled_Br_20061229160134007_S19971_I34734
On a T1-weighted brain MRI we observed: For the ventricles: - the 4th ventricle shows no notable changes suggestive of enlargement - no findings suggestive of enlargement are seen in the external csf - 3rd ventricle maintains its expected proportions without signs of enlargement - inf. lateral ventricle maintains a typical volume without observable enlargement - the lateral ventricle shows no notable changes suggestive of enlargement For the subcortical structures: - basal forebrain maintains a normal appearance with no observable atrophic features - amygdala appears preserved, with no observable tissue loss - no appreciable degenerative or atrophic changes observed in the caudate - accumbens appears within normal limits without apparent atrophy - no evident atrophy or tissue thinning seen in the thalamus - mild atrophy of the left putamen; normal-to-mild atrophy of the right putamen - no observable atrophic changes in the pallidum - no clear atrophic alterations are visible in the ventral dc - no observable atrophic changes in the hippocampus For the cerebral cortex: - the temporal lobe shows no notable changes suggestive of atrophy - no observable atrophic changes in the occipital lobe - no observable atrophic changes in the parietal lobe - mild atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: parietal operculum (mild atrophy both left/right), anterior insula (mild atrophy on the left and normal on the right) and frontal operculum (mild atrophy on the left and normal on the right) - no appreciable degenerative or atrophic changes observed in the frontal lobe - the limbic cortex shows no notable changes suggestive of atrophy
CN
FTLD_203833156_02653_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178165
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no appreciable degenerative or atrophic changes observed in the parietal lobe - mild atrophy of the right limbic cortex; normal-to-mild atrophy of the left limbic cortex; focal volume loss observed in the following subregions: entorhinal area (mild-to-moderate atrophy on the left and mild atrophy on the right) and parahippocampal gyrus (mild atrophy both left/right) - no clear atrophic alterations are visible in the frontal lobe - occipital lobe demonstrates a healthy morphology without signs of atrophy - severe atrophy of the left temporal lobe and mild-to-moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), middle temporal gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), fusiform gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), planum temporale (normal-to-mild atrophy on the left and mild atrophy on the right), inf. temporal gyrus (mild-to-moderate atrophy on the left and normal on the right) and sup. temporal gyrus (mild-to-moderate atrophy on the left and normal on the right) - mild-to-moderate bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), posterior insula (moderate atrophy on the left and mild-to-moderate atrophy on the right), central operculum (mild atrophy on the right) and parietal operculum (normal on the left and mild atrophy on the right) For the subcortical structures: - severe atrophy of the left amygdala and moderate-to-severe atrophy of the right amygdala - mild-to-moderate atrophy of the left putamen; the right putamen is normal - no observable atrophic changes in the ventral dc - mild-to-moderate atrophy of the left hippocampus - the left hippocampus volume is borderline low - no findings suggestive of atrophy are seen in the caudate - thalamus demonstrates a healthy morphology without signs of atrophy - mild-to-moderate atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens - no findings suggestive of atrophy are seen in the pallidum - no clear atrophic alterations are visible in the basal forebrain For the ventricles: - the 4th ventricle shows no notable changes suggestive of enlargement - no clear enlargement or abnormal growth seen in the lateral ventricle - mild enlargement of the external csf - severe enlargement of the left inf. lateral ventricle and mild-to-moderate enlargement of the right inf. lateral ventricle - 3rd ventricle maintains its expected proportions without signs of enlargement
SV
FTLD_203260125_02526_MR_Sagittal_MP-Rage_br_raw_20230206161248652_I10181566
On a T1-weighted brain MRI we observed: For the ventricles: - mild enlargement of the 4th ventricle - moderate enlargement of the 3rd ventricle - mild-to-moderate enlargement of the external csf - moderate bilateral enlargement of the inf. lateral ventricle - mild enlargement of the left lateral ventricle and mild-to-moderate enlargement of the right lateral ventricle For the subcortical structures: - mild bilateral atrophy of the caudate - the amygdala shows no notable changes suggestive of atrophy - mild atrophy of the right accumbens; normal-to-mild atrophy of the left accumbens - pallidum maintains a normal appearance with no observable atrophic features - no observable atrophic changes in the basal forebrain - no appreciable degenerative or atrophic changes observed in the ventral dc - the putamen shows no notable changes suggestive of atrophy - no appreciable degenerative or atrophic changes observed in the hippocampus - mild bilateral atrophy of the thalamus For the cerebral cortex: - mild bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: frontal operculum (mild atrophy both left/right) and parietal operculum (mild atrophy on the left and normal-to-mild atrophy on the right) - mild atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: fusiform gyrus (mild-to-moderate atrophy both left/right), transverse temporal gyrus (mild atrophy on the right), planum temporale (normal-to-mild atrophy on the left and mild atrophy on the right) and sup. temporal gyrus (mild atrophy on the right) - the parietal lobe shows no notable changes suggestive of atrophy - occipital lobe appears preserved, with no observable tissue loss - the limbic cortex shows no notable changes suggestive of atrophy - mild-to-moderate atrophy of the left frontal lobe and moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: precentral gyrus medial segment (mild atrophy on the left and mild-to-moderate atrophy on the right), sup. frontal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), precentral gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), supplementary motor cortex (mild atrophy both left/right), middle frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), lateral orbital gyrus (mild atrophy on the left and normal on the right), gyrus rectus (mild atrophy on the left and normal on the right), medial frontal cortex (mild atrophy on the left) and sup. frontal gyrus medial segment (normal on the left and mild atrophy on the right)
PNFA
FTLD_203184740_03048_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177079
On a T1-weighted brain MRI we observed: For the cerebral cortex: - frontal lobe appears within normal limits without apparent atrophy - the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in transverse temporal gyrus (normal on the left and severe atrophy on the right) and sup. temporal gyrus (normal on the left and mild atrophy on the right) - the limbic cortex shows no notable changes suggestive of atrophy - no findings suggestive of atrophy are seen in the parietal lobe - no observable atrophic changes in the occipital lobe - insular cortex demonstrates a healthy morphology without signs of atrophy For the ventricles: - no clear enlargement or abnormal growth seen in the lateral ventricle - 3rd ventricle appears within normal size limits with no apparent enlargement - no observable enlargement of the external csf - no appreciable enlargement noted in the inf. lateral ventricle - 4th ventricle maintains its expected proportions without signs of enlargement For the subcortical structures: - no appreciable degenerative or atrophic changes observed in the hippocampus - no appreciable degenerative or atrophic changes observed in the caudate - accumbens appears preserved, with no observable tissue loss - no appreciable degenerative or atrophic changes observed in the thalamus - no clear atrophic alterations are visible in the ventral dc - no findings suggestive of atrophy are seen in the amygdala - no observable atrophic changes in the pallidum - basal forebrain demonstrates a healthy morphology without signs of atrophy - putamen appears within normal limits without apparent atrophy
CN
FTLD_203537998_01893_MR_Sagittal_MP-Rage_br_raw_20230206152126880_I10181373
On a T1-weighted brain MRI we observed: For the subcortical structures: - no appreciable degenerative or atrophic changes observed in the thalamus - mild-to-moderate bilateral atrophy of the accumbens - hippocampus maintains a normal appearance with no observable atrophic features - amygdala appears preserved, with no observable tissue loss - caudate maintains a normal appearance with no observable atrophic features - basal forebrain demonstrates a healthy morphology without signs of atrophy - pallidum demonstrates a healthy morphology without signs of atrophy - putamen maintains a normal appearance with no observable atrophic features - no evident atrophy or tissue thinning seen in the ventral dc For the cerebral cortex: - mild-to-moderate atrophy of the right limbic cortex; normal-to-mild atrophy of the left limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and middle cingulate gyrus (normal on the left and mild atrophy on the right) - temporal lobe appears preserved, with no observable tissue loss - mild atrophy of the right insular cortex; normal-to-mild atrophy of the left insular cortex; focal volume loss observed in the following subregions: parietal operculum (mild atrophy on the left and mild-to-moderate atrophy on the right) and central operculum (mild atrophy both left/right) - mild atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: precentral gyrus medial segment (mild-to-moderate atrophy on the left and mild atrophy on the right), anterior orbital gyrus (mild atrophy on the left), gyrus rectus (mild atrophy on the left and normal-to-mild atrophy on the right), lateral orbital gyrus (mild-to-moderate atrophy on the left) and sup. frontal gyrus medial segment (mild atrophy on the left and normal on the right) - occipital lobe appears within normal limits without apparent atrophy - mild atrophy of the right parietal lobe; normal-to-mild atrophy of the left parietal lobe; focal volume loss observed in the following subregions: supramarginal gyrus (mild atrophy both left/right) and postcentral gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) For the ventricles: - severe enlargement of the left inf. lateral ventricle and moderate enlargement of the right inf. lateral ventricle - mild-to-moderate enlargement of the 3rd ventricle - moderate-to-severe bilateral enlargement of the lateral ventricle - no evident size increase noted in the 4th ventricle - external csf maintains its expected proportions without signs of enlargement
BV
FTLD_203520125_02522_MR_Sagittal_MP-Rage_br_raw_20230206161149625_I10181563
On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (mild atrophy both left/right) and central operculum (mild atrophy both left/right) - parietal lobe appears preserved, with no observable tissue loss - mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the left) - mild atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: inf. temporal gyrus (mild atrophy both left/right) - mild-to-moderate atrophy of the left frontal lobe and mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: precentral gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), sup. frontal gyrus medial segment (mild-to-moderate atrophy on the right), lateral orbital gyrus (mild atrophy on the left), medial frontal cortex (mild atrophy on the left and normal on the right), sup. frontal gyrus (mild atrophy on the left and normal on the right), supplementary motor cortex (normal on the left and mild atrophy on the right), middle frontal gyrus (mild atrophy on the left and normal on the right), anterior orbital gyrus (mild atrophy on the left and normal on the right) and posterior orbital gyrus (mild atrophy on the right) - no observable atrophic changes in the occipital lobe For the ventricles: - mild enlargement of the external csf - 3rd ventricle maintains its expected proportions without signs of enlargement - moderate enlargement of the left lateral ventricle and moderate-to-severe enlargement of the right lateral ventricle - mild enlargement of the 4th ventricle - mild-to-moderate enlargement of the left inf. lateral ventricle; normal-to-mild enlargement of the right inf. lateral ventricle For the subcortical structures: - mild bilateral atrophy of the accumbens - caudate appears preserved, with no observable tissue loss - mild-to-moderate atrophy of the left putamen and mild atrophy of the right putamen - mild atrophy of the left ventral dc; the right ventral dc is normal - the basal forebrain shows no notable changes suggestive of atrophy - the left hippocampus volume is borderline low - amygdala appears preserved, with no observable tissue loss - the pallidum shows no notable changes suggestive of atrophy - mild atrophy of the left thalamus; normal-to-mild atrophy of the right thalamus
PNFA
ADNI_137_S_6826_MR_Accelerated_Sagittal_MPRAGE__br_raw_20191018122908626_185_S885472_I1242424
On a T1-weighted brain MRI we observed: For the subcortical structures: - no clear atrophic alterations are visible in the hippocampus - pallidum demonstrates a healthy morphology without signs of atrophy - putamen demonstrates a healthy morphology without signs of atrophy - amygdala demonstrates a healthy morphology without signs of atrophy - no appreciable degenerative or atrophic changes observed in the ventral dc - no observable atrophic changes in the caudate - mild-to-moderate atrophy of the left thalamus and mild atrophy of the right thalamus - mild atrophy of the right accumbens; normal-to-mild atrophy of the left accumbens - the basal forebrain shows no notable changes suggestive of atrophy For the cerebral cortex: - the temporal lobe shows no notable changes suggestive of atrophy - limbic cortex maintains a normal appearance with no observable atrophic features - no clear atrophic alterations are visible in the insular cortex - occipital lobe maintains a normal appearance with no observable atrophic features - mild atrophy of the right frontal lobe; normal-to-mild atrophy of the left frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), medial orbital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and sup. frontal gyrus medial segment (mild atrophy on the right) - no appreciable degenerative or atrophic changes observed in the parietal lobe For the ventricles: - moderate enlargement of the external csf - mild enlargement of the left inf. lateral ventricle and mild-to-moderate enlargement of the right inf. lateral ventricle - the 4th ventricle shows no notable changes suggestive of enlargement - lateral ventricle appears within normal size limits with no apparent enlargement - mild-to-moderate enlargement of the 3rd ventricle
CN
FTLD_203977632_02237_MR_Sagittal_MP-Rage_br_raw_20230206180257105_I10182344
On a T1-weighted brain MRI we observed: For the subcortical structures: - hippocampus appears preserved, with no observable tissue loss - putamen appears preserved, with no observable tissue loss - accumbens appears preserved, with no observable tissue loss - no observable atrophic changes in the pallidum - no observable atrophic changes in the thalamus - the caudate shows no notable changes suggestive of atrophy - the basal forebrain shows no notable changes suggestive of atrophy - amygdala appears within normal limits without apparent atrophy - no appreciable degenerative or atrophic changes observed in the ventral dc For the ventricles: - 3rd ventricle appears to be of normal dimensions, with no observable increase in size - no observable enlargement of the lateral ventricle - no findings suggestive of enlargement are seen in the 4th ventricle - no evident size increase noted in the inf. lateral ventricle - no appreciable enlargement noted in the external csf For the cerebral cortex: - insular cortex demonstrates a healthy morphology without signs of atrophy - no observable atrophic changes in the frontal lobe - no observable atrophic changes in the occipital lobe - parietal lobe demonstrates a healthy morphology without signs of atrophy - no clear atrophic alterations are visible in the temporal lobe - the limbic cortex shows no notable changes suggestive of atrophy
CN
FTLD_203608227_03720_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10451105
On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild-to-moderate atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: anterior orbital gyrus (moderate atrophy both left/right), precentral gyrus (moderate atrophy on the left and mild atrophy on the right), middle frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), supplementary motor cortex (mild atrophy on the left) and opercular inf. frontal gyrus (mild atrophy on the left) - limbic cortex appears preserved, with no observable tissue loss - moderate atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: central operculum (moderate atrophy on the left and normal-to-mild atrophy on the right), anterior insula (mild atrophy both left/right), parietal operculum (mild atrophy both left/right) and frontal operculum (mild atrophy on the left and normal on the right) - mild-to-moderate atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: middle temporal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), temporal pole (mild atrophy both left/right), planum temporale (mild atrophy on the left and normal-to-mild atrophy on the right) and transverse temporal gyrus (mild atrophy on the left and normal on the right) - mild-to-moderate atrophy of the left parietal lobe; the right parietal lobe is normal; focal volume loss observed in the following subregions: precuneus (mild atrophy on the left and normal-to-mild atrophy on the right), postcentral gyrus (mild atrophy on the left and normal on the right), sup. parietal lobule (mild atrophy on the left and normal on the right) and supramarginal gyrus (mild atrophy on the left) - mild atrophy of the left occipital lobe; normal-to-mild atrophy of the right occipital lobe; focal volume loss observed in the following subregions: occipital pole (normal-to-mild atrophy on the left and mild atrophy on the right) and inf. occipital gyrus (mild atrophy on the left and normal on the right) For the subcortical structures: - moderate-to-severe atrophy of the left thalamus and mild-to-moderate atrophy of the right thalamus - no evident atrophy or tissue thinning seen in the amygdala - no evident atrophy or tissue thinning seen in the basal forebrain - mild atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens - moderate-to-severe atrophy of the left caudate and mild-to-moderate atrophy of the right caudate - moderate atrophy of the left pallidum and mild atrophy of the right pallidum - moderate atrophy of the left hippocampus - mild-to-moderate atrophy of the right hippocampus - moderate-to-severe atrophy of the left putamen and mild-to-moderate atrophy of the right putamen - mild-to-moderate atrophy of the left ventral dc and mild atrophy of the right ventral dc For the ventricles: - mild-to-moderate enlargement of the 4th ventricle - severe bilateral enlargement of the inf. lateral ventricle - external csf maintains its expected proportions without signs of enlargement - mild enlargement of the 3rd ventricle - severe bilateral enlargement of the lateral ventricle
BV
ADNI_033_S_6572_MR_Accelerated_Sagittal_MPRAGE__br_raw_20180905092530775_154_S724488_I1045204
On a T1-weighted brain MRI we observed: For the ventricles: - external csf appears within normal size limits with no apparent enlargement - 4th ventricle appears within normal size limits with no apparent enlargement - no evident size increase noted in the 3rd ventricle - the lateral ventricle shows no notable changes suggestive of enlargement - inf. lateral ventricle maintains a typical volume without observable enlargement For the subcortical structures: - putamen appears within normal limits without apparent atrophy - caudate maintains a normal appearance with no observable atrophic features - ventral dc appears preserved, with no observable tissue loss - the hippocampus shows no notable changes suggestive of atrophy - thalamus appears preserved, with no observable tissue loss - basal forebrain appears within normal limits without apparent atrophy - no clear atrophic alterations are visible in the pallidum - no appreciable degenerative or atrophic changes observed in the accumbens - amygdala appears within normal limits without apparent atrophy For the cerebral cortex: - no findings suggestive of atrophy are seen in the insular cortex - no evident atrophy or tissue thinning seen in the parietal lobe - mild bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: middle temporal gyrus (mild atrophy both left/right), temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right) and planum temporale (mild atrophy on the right) - the occipital lobe shows no notable changes suggestive of atrophy - no clear atrophic alterations are visible in the frontal lobe - no appreciable degenerative or atrophic changes observed in the limbic cortex
CN
FTLD_203520125_02522_MR_Sagittal_MP-Rage_br_raw_20230206161149625_I10181563
On a T1-weighted brain MRI we observed: For the subcortical structures: - caudate appears within normal limits without apparent atrophy - mild atrophy of the left thalamus; normal-to-mild atrophy of the right thalamus - no findings suggestive of atrophy are seen in the pallidum - mild atrophy of the left ventral dc; the right ventral dc is normal - the left hippocampus volume is borderline low - mild-to-moderate atrophy of the left putamen and mild atrophy of the right putamen - the basal forebrain shows no notable changes suggestive of atrophy - mild bilateral atrophy of the accumbens - no clear atrophic alterations are visible in the amygdala For the cerebral cortex: - mild atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: inf. temporal gyrus (mild atrophy both left/right) - mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the left) - no findings suggestive of atrophy are seen in the occipital lobe - mild-to-moderate atrophy of the left frontal lobe and mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: precentral gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), sup. frontal gyrus medial segment (mild-to-moderate atrophy on the right), lateral orbital gyrus (mild atrophy on the left), medial frontal cortex (mild atrophy on the left and normal on the right), sup. frontal gyrus (mild atrophy on the left and normal on the right), supplementary motor cortex (normal on the left and mild atrophy on the right), middle frontal gyrus (mild atrophy on the left and normal on the right), anterior orbital gyrus (mild atrophy on the left and normal on the right) and posterior orbital gyrus (mild atrophy on the right) - mild atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (mild atrophy both left/right) and central operculum (mild atrophy both left/right) - parietal lobe demonstrates a healthy morphology without signs of atrophy For the ventricles: - mild enlargement of the 4th ventricle - mild enlargement of the external csf - no clear enlargement or abnormal growth seen in the 3rd ventricle - moderate enlargement of the left lateral ventricle and moderate-to-severe enlargement of the right lateral ventricle - mild-to-moderate enlargement of the left inf. lateral ventricle; normal-to-mild enlargement of the right inf. lateral ventricle
PNFA
FTLD_203471402_03207_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178329
On a T1-weighted brain MRI we observed: For the cerebral cortex: - occipital lobe maintains a normal appearance with no observable atrophic features - mild-to-moderate atrophy of the left limbic cortex and moderate-to-severe atrophy of the right limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (moderate atrophy both left/right), entorhinal area (mild atrophy on the left and moderate-to-severe atrophy on the right) and parahippocampal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right) - mild-to-moderate atrophy of the left frontal lobe and severe atrophy of the right frontal lobe; focal volume loss observed in the following subregions: medial orbital gyrus (mild-to-moderate atrophy on the left and moderate-to-severe atrophy on the right), gyrus rectus (mild atrophy on the left and moderate-to-severe atrophy on the right), lateral orbital gyrus (mild-to-moderate atrophy both left/right), medial frontal cortex (mild atrophy both left/right), frontal pole (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), posterior orbital gyrus (mild atrophy both left/right), subcallosal area (mild atrophy both left/right), sup. frontal gyrus medial segment (normal on the left and mild-to-moderate atrophy on the right), middle frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), anterior orbital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), supplementary motor cortex (normal on the left and mild atrophy on the right), opercular inf. frontal gyrus (normal on the left and mild atrophy on the right) and precentral gyrus medial segment (mild atrophy on the right) - mild-to-moderate atrophy of the left temporal lobe and severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (mild-to-moderate atrophy on the left and severe atrophy on the right), inf. temporal gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), fusiform gyrus (normal on the left and mild-to-moderate atrophy on the right), middle temporal gyrus (normal on the left and mild atrophy on the right) and sup. temporal gyrus (mild atrophy on the right) - parietal lobe appears preserved, with no observable tissue loss - mild-to-moderate atrophy of the left insular cortex and moderate atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (severe atrophy both left/right), posterior insula (normal-to-mild atrophy on the left and moderate atrophy on the right) and frontal operculum (normal-to-mild atrophy on the left and mild atrophy on the right) For the subcortical structures: - no observable atrophic changes in the pallidum - severe bilateral atrophy of the amygdala - mild-to-moderate atrophy of the left caudate and moderate atrophy of the right caudate - severe bilateral atrophy of the accumbens - severe atrophy of the right hippocampus - thalamus appears within normal limits without apparent atrophy - no observable atrophic changes in the ventral dc - mild atrophy of the left putamen and moderate atrophy of the right putamen - no findings suggestive of atrophy are seen in the basal forebrain For the ventricles: - moderate enlargement of the external csf - mild enlargement of the 3rd ventricle - 4th ventricle maintains its expected proportions without signs of enlargement - no appreciable enlargement noted in the lateral ventricle - severe enlargement of the right inf. lateral ventricle; normal-to-mild enlargement of the left inf. lateral ventricle
BV
FTLD_203089629_02928_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177882
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no clear atrophic alterations are visible in the occipital lobe - mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: parahippocampal gyrus (mild atrophy on the left) and entorhinal area (mild atrophy on the left and normal on the right) - severe atrophy of the left temporal lobe and moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (severe atrophy on the left and moderate-to-severe atrophy on the right), inf. temporal gyrus (moderate-to-severe atrophy on the left and mild atrophy on the right), middle temporal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. temporal gyrus (mild-to-moderate atrophy on the left and normal on the right) and planum polare (mild atrophy on the left) - parietal lobe demonstrates a healthy morphology without signs of atrophy - frontal lobe maintains a normal appearance with no observable atrophic features - no observable atrophic changes in the insular cortex For the subcortical structures: - no findings suggestive of atrophy are seen in the thalamus - mild-to-moderate atrophy of the left hippocampus - ventral dc maintains a normal appearance with no observable atrophic features - pallidum demonstrates a healthy morphology without signs of atrophy - the putamen shows no notable changes suggestive of atrophy - no clear atrophic alterations are visible in the accumbens - caudate appears preserved, with no observable tissue loss - severe atrophy of the left amygdala and mild-to-moderate atrophy of the right amygdala - no observable atrophic changes in the basal forebrain For the ventricles: - mild enlargement of the external csf - the 3rd ventricle shows no notable changes suggestive of enlargement - moderate enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal - lateral ventricle maintains a typical volume without observable enlargement - no evident size increase noted in the 4th ventricle
SV
FTLD_203030127_03723_MR_Accelerated_Sagittal_MPRAGE_br_raw_20241_I11047718
On a T1-weighted brain MRI we observed: For the subcortical structures: - the caudate shows no notable changes suggestive of atrophy - no evident atrophy or tissue thinning seen in the basal forebrain - hippocampus appears preserved, with no observable tissue loss - pallidum appears preserved, with no observable tissue loss - no appreciable degenerative or atrophic changes observed in the amygdala - no clear atrophic alterations are visible in the putamen - ventral dc maintains a normal appearance with no observable atrophic features - no appreciable degenerative or atrophic changes observed in the accumbens - no findings suggestive of atrophy are seen in the thalamus For the ventricles: - no evident size increase noted in the 3rd ventricle - external csf appears within normal size limits with no apparent enlargement - the 4th ventricle shows no notable changes suggestive of enlargement - inf. lateral ventricle maintains its expected proportions without signs of enlargement - lateral ventricle maintains its expected proportions without signs of enlargement For the cerebral cortex: - parietal lobe demonstrates a healthy morphology without signs of atrophy - mild-to-moderate atrophy of the left frontal lobe and mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: gyrus rectus (mild atrophy on the left and normal-to-mild atrophy on the right), lateral orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), precentral gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), medial frontal cortex (normal on the left and mild atrophy on the right) and triangular inf. frontal gyrus (normal on the left and mild atrophy on the right) - no evident atrophy or tissue thinning seen in the occipital lobe - mild bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: middle temporal gyrus (mild atrophy both left/right) and temporal pole (mild atrophy both left/right) - limbic cortex appears preserved, with no observable tissue loss - no evident atrophy or tissue thinning seen in the insular cortex
PNFA
ADNI_023_S_10173_MR_Accelerated_Sagittal_MPRAGE_MSV21_br_raw_20240719184108324_1_I10883255
On a T1-weighted brain MRI we observed: For the cerebral cortex: - parietal lobe demonstrates a healthy morphology without signs of atrophy - no findings suggestive of atrophy are seen in the frontal lobe - the insular cortex shows no notable changes suggestive of atrophy - no findings suggestive of atrophy are seen in the limbic cortex - no appreciable degenerative or atrophic changes observed in the occipital lobe - no evident atrophy or tissue thinning seen in the temporal lobe For the subcortical structures: - no evident atrophy or tissue thinning seen in the thalamus - no observable atrophic changes in the basal forebrain - no evident atrophy or tissue thinning seen in the putamen - no findings suggestive of atrophy are seen in the amygdala - no evident atrophy or tissue thinning seen in the caudate - no clear atrophic alterations are visible in the pallidum - no appreciable degenerative or atrophic changes observed in the hippocampus - ventral dc maintains a normal appearance with no observable atrophic features - accumbens appears within normal limits without apparent atrophy For the ventricles: - no observable enlargement of the 4th ventricle - external csf appears to be of normal dimensions, with no observable increase in size - lateral ventricle maintains a typical volume without observable enlargement - 3rd ventricle maintains a typical volume without observable enlargement - no evident size increase noted in the inf. lateral ventricle
CN
FTLD_203638978_01873_MR_Sagittal_MP-Rage_br_raw_20230206175220725_I10182269
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild bilateral atrophy of the ventral dc - moderate atrophy of the left accumbens and mild atrophy of the right accumbens - moderate atrophy of the left caudate and mild atrophy of the right caudate - basal forebrain appears within normal limits without apparent atrophy - mild-to-moderate atrophy of the left putamen; normal-to-mild atrophy of the right putamen - mild-to-moderate atrophy of the left thalamus; normal-to-mild atrophy of the right thalamus - mild atrophy of the left hippocampus - amygdala maintains a normal appearance with no observable atrophic features - mild-to-moderate atrophy of the left pallidum and mild atrophy of the right pallidum For the cerebral cortex: - no observable atrophic changes in the occipital lobe - moderate atrophy of the left frontal lobe and mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (mild-to-moderate atrophy both left/right), sup. frontal gyrus medial segment (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), precentral gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), gyrus rectus (mild atrophy on the left and normal on the right) and medial orbital gyrus (mild atrophy on the left) - mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) - mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and normal on the right) - temporal lobe appears preserved, with no observable tissue loss - parietal lobe appears preserved, with no observable tissue loss For the ventricles: - mild-to-moderate enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal - mild-to-moderate enlargement of the external csf - mild-to-moderate bilateral enlargement of the lateral ventricle - 4th ventricle appears within normal size limits with no apparent enlargement - 3rd ventricle maintains its expected proportions without signs of enlargement
BV
FTLD_203756460_03065_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10177394
On a T1-weighted brain MRI we observed: For the subcortical structures: - ventral dc maintains a normal appearance with no observable atrophic features - no observable atrophic changes in the basal forebrain - moderate-to-severe atrophy of the left amygdala and moderate atrophy of the right amygdala - pallidum demonstrates a healthy morphology without signs of atrophy - mild atrophy of the left hippocampus - mild atrophy of the left caudate; normal-to-mild atrophy of the right caudate - accumbens demonstrates a healthy morphology without signs of atrophy - no observable atrophic changes in the putamen - thalamus appears preserved, with no observable tissue loss For the ventricles: - mild enlargement of the 3rd ventricle - 4th ventricle maintains its expected proportions without signs of enlargement - mild-to-moderate enlargement of the external csf - lateral ventricle appears within normal size limits with no apparent enlargement - severe enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle For the cerebral cortex: - moderate atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate atrophy on the left and mild-to-moderate atrophy on the right), fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), inf. temporal gyrus (mild atrophy on the left and normal on the right) and middle temporal gyrus (mild atrophy on the left and normal on the right) - mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (mild-to-moderate atrophy on the left and mild atrophy on the right), parahippocampal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and middle cingulate gyrus (mild atrophy on the left) - no clear atrophic alterations are visible in the parietal lobe - mild atrophy of the left frontal lobe; normal-to-mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), medial frontal cortex (mild atrophy on the left and normal-to-mild atrophy on the right), anterior orbital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), gyrus rectus (mild atrophy on the left and normal on the right) and posterior orbital gyrus (normal on the left and mild atrophy on the right) - no appreciable degenerative or atrophic changes observed in the occipital lobe - no observable atrophic changes in the insular cortex
SV
FTLD_203666905_03506_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450860
On a T1-weighted brain MRI we observed: For the cerebral cortex: - occipital lobe appears within normal limits without apparent atrophy - the frontal lobe shows no notable changes suggestive of atrophy - mild bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: anterior insula (mild-to-moderate atrophy both left/right) and central operculum (normal-to-mild atrophy on the left and mild atrophy on the right) - no evident atrophy or tissue thinning seen in the temporal lobe - parietal lobe appears within normal limits without apparent atrophy - limbic cortex appears within normal limits without apparent atrophy For the ventricles: - moderate enlargement of the left lateral ventricle and severe enlargement of the right lateral ventricle - moderate-to-severe enlargement of the 3rd ventricle - mild-to-moderate enlargement of the 4th ventricle - mild-to-moderate enlargement of the left inf. lateral ventricle and severe enlargement of the right inf. lateral ventricle - external csf maintains its expected proportions without signs of enlargement For the subcortical structures: - the left hippocampus volume is borderline low - the basal forebrain shows no notable changes suggestive of atrophy - no findings suggestive of atrophy are seen in the caudate - mild atrophy of the right amygdala; the left amygdala is normal - mild-to-moderate bilateral atrophy of the accumbens - mild atrophy of the left putamen and mild-to-moderate atrophy of the right putamen - mild-to-moderate bilateral atrophy of the ventral dc - mild-to-moderate bilateral atrophy of the thalamus - mild-to-moderate atrophy of the left pallidum and moderate atrophy of the right pallidum
PNFA
ADNI_052_S_10267_MR_Accelerated_Sagittal_MPRAGE_MSV21_br_raw_20241101184401013_1_I11039385
On a T1-weighted brain MRI we observed: For the ventricles: - lateral ventricle maintains a typical volume without observable enlargement - no appreciable enlargement noted in the 3rd ventricle - inf. lateral ventricle maintains a typical volume without observable enlargement - no findings suggestive of enlargement are seen in the external csf - no findings suggestive of enlargement are seen in the 4th ventricle For the cerebral cortex: - no observable atrophic changes in the limbic cortex - no observable atrophic changes in the temporal lobe - no appreciable degenerative or atrophic changes observed in the parietal lobe - frontal lobe maintains a normal appearance with no observable atrophic features - no findings suggestive of atrophy are seen in the insular cortex - no clear atrophic alterations are visible in the occipital lobe For the subcortical structures: - no evident atrophy or tissue thinning seen in the pallidum - no observable atrophic changes in the putamen - the amygdala shows no notable changes suggestive of atrophy - mild atrophy of the left hippocampus - no appreciable degenerative or atrophic changes observed in the accumbens - no evident atrophy or tissue thinning seen in the ventral dc - no evident atrophy or tissue thinning seen in the basal forebrain - thalamus appears preserved, with no observable tissue loss - no evident atrophy or tissue thinning seen in the caudate
CN
ADNI_023_S_5120_MR_MPRAGE_GRAPPA2_br_raw_20130515153208092_97_S189446_I372410
On a T1-weighted brain MRI we observed: For the subcortical structures: - pallidum demonstrates a healthy morphology without signs of atrophy - no observable atrophic changes in the ventral dc - no evident atrophy or tissue thinning seen in the caudate - mild atrophy of the right basal forebrain; the left basal forebrain is normal - hippocampus maintains a normal appearance with no observable atrophic features - no evident atrophy or tissue thinning seen in the thalamus - no appreciable degenerative or atrophic changes observed in the amygdala - mild atrophy of the right putamen; normal-to-mild atrophy of the left putamen - no observable atrophic changes in the accumbens For the ventricles: - no clear enlargement or abnormal growth seen in the external csf - the 4th ventricle shows no notable changes suggestive of enlargement - inf. lateral ventricle appears within normal size limits with no apparent enlargement - no observable enlargement of the lateral ventricle - the 3rd ventricle shows no notable changes suggestive of enlargement For the cerebral cortex: - no observable atrophic changes in the frontal lobe - parietal lobe appears preserved, with no observable tissue loss - no evident atrophy or tissue thinning seen in the occipital lobe - temporal lobe appears within normal limits without apparent atrophy - no clear atrophic alterations are visible in the insular cortex - no evident atrophy or tissue thinning seen in the limbic cortex
AD
ADNI_036_S_4491_MR_MPRAGE_br_raw_20120201100141402_26_S139086_I281772
On a T1-weighted brain MRI we observed: For the cerebral cortex: - the parietal lobe shows no notable changes suggestive of atrophy - frontal lobe appears preserved, with no observable tissue loss - mild atrophy of the right occipital lobe; the left occipital lobe is normal; focal volume loss observed in the following subregions: calcarine cortex (normal-to-mild atrophy on the left and mild atrophy on the right) and occipital pole (normal on the left and mild-to-moderate atrophy on the right) - no appreciable degenerative or atrophic changes observed in the temporal lobe - insular cortex demonstrates a healthy morphology without signs of atrophy - no clear atrophic alterations are visible in the limbic cortex For the ventricles: - mild bilateral enlargement of the inf. lateral ventricle - no findings suggestive of enlargement are seen in the external csf - no findings suggestive of enlargement are seen in the 3rd ventricle - lateral ventricle maintains its expected proportions without signs of enlargement - no evident size increase noted in the 4th ventricle For the subcortical structures: - the accumbens shows no notable changes suggestive of atrophy - no clear atrophic alterations are visible in the thalamus - putamen maintains a normal appearance with no observable atrophic features - ventral dc maintains a normal appearance with no observable atrophic features - pallidum demonstrates a healthy morphology without signs of atrophy - caudate appears preserved, with no observable tissue loss - amygdala demonstrates a healthy morphology without signs of atrophy - hippocampus appears within normal limits without apparent atrophy - no evident atrophy or tissue thinning seen in the basal forebrain
CN
FTLD_203788719_01918_MR_Sagittal_MP-Rage_br_raw_20230206152255569_I10181377
On a T1-weighted brain MRI we observed: For the subcortical structures: - thalamus appears preserved, with no observable tissue loss - no findings suggestive of atrophy are seen in the accumbens - no appreciable degenerative or atrophic changes observed in the pallidum - ventral dc appears preserved, with no observable tissue loss - basal forebrain appears within normal limits without apparent atrophy - amygdala appears within normal limits without apparent atrophy - no observable atrophic changes in the hippocampus - caudate maintains a normal appearance with no observable atrophic features - mild atrophy of the left putamen; normal-to-mild atrophy of the right putamen For the ventricles: - 3rd ventricle appears to be of normal dimensions, with no observable increase in size - no appreciable enlargement noted in the 4th ventricle - no appreciable enlargement noted in the external csf - the inf. lateral ventricle shows no notable changes suggestive of enlargement - the lateral ventricle shows no notable changes suggestive of enlargement For the cerebral cortex: - mild atrophy of the left frontal lobe; normal-to-mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: precentral gyrus (moderate atrophy on the left and normal-to-mild atrophy on the right), sup. frontal gyrus medial segment (mild atrophy on the left and normal-to-mild atrophy on the right) and anterior orbital gyrus (mild atrophy on the right) - no clear atrophic alterations are visible in the parietal lobe - moderate-to-severe atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: central operculum (moderate atrophy on the left and mild atrophy on the right), anterior insula (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) and parietal operculum (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) - no clear atrophic alterations are visible in the limbic cortex - occipital lobe appears within normal limits without apparent atrophy - no clear atrophic alterations are visible in the temporal lobe
PNFA