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FTLD_203011672_03271_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177308
On a T1-weighted brain MRI we observed: For the cerebral cortex: - moderate atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), posterior insula (mild-to-moderate atrophy on the left and mild atrophy on the right) and central operculum (mild atrophy on the left and normal on the right) - the occipital lobe shows no notable changes suggestive of atrophy - severe atrophy of the left temporal lobe and moderate-to-severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (severe atrophy on the left and moderate-to-severe atrophy on the right), inf. temporal gyrus (mild-to-moderate atrophy on the left and moderate atrophy on the right), middle temporal gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), planum polare (mild atrophy both left/right), sup. temporal gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) and fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) - mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (moderate atrophy on the left and mild-to-moderate atrophy on the right) and parahippocampal gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right) - mild atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: triangular inf. frontal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), gyrus rectus (mild atrophy both left/right), supplementary motor cortex (normal-to-mild atrophy on the left and mild atrophy on the right), medial orbital gyrus (mild atrophy on the left and normal on the right) and posterior orbital gyrus (normal on the left and mild atrophy on the right) - parietal lobe appears within normal limits without apparent atrophy For the ventricles: - moderate enlargement of the 3rd ventricle - mild enlargement of the external csf - severe enlargement of the left inf. lateral ventricle and moderate enlargement of the right inf. lateral ventricle - moderate enlargement of the left lateral ventricle and mild enlargement of the right lateral ventricle - 4th ventricle appears within normal size limits with no apparent enlargement For the subcortical structures: - moderate-to-severe atrophy of the left hippocampus - moderate atrophy of the right hippocampus - no evident atrophy or tissue thinning seen in the thalamus - mild-to-moderate atrophy of the left caudate and mild atrophy of the right caudate - mild-to-moderate atrophy of the left pallidum; normal-to-mild atrophy of the right pallidum - severe bilateral atrophy of the amygdala - moderate-to-severe atrophy of the left accumbens and mild atrophy of the right accumbens - severe atrophy of the left putamen and moderate atrophy of the right putamen - the ventral dc shows no notable changes suggestive of atrophy - no evident atrophy or tissue thinning seen in the basal forebrain
SV
ADNI_027_S_0404_MR_MPR__GradWarp__B1_Correction__N3__Scaled_Br_20061222194841960_S13866_I34204
On a T1-weighted brain MRI we observed: For the ventricles: - mild enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal - lateral ventricle appears to be of normal dimensions, with no observable increase in size - external csf maintains a typical volume without observable enlargement - no evident size increase noted in the 3rd ventricle - 4th ventricle maintains a typical volume without observable enlargement For the cerebral cortex: - frontal lobe appears preserved, with no observable tissue loss - mild-to-moderate atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: temporal pole (moderate atrophy on the left and mild-to-moderate atrophy on the right), middle temporal gyrus (mild-to-moderate atrophy on the left) and sup. temporal gyrus (mild atrophy on the right) - insular cortex appears within normal limits without apparent atrophy - parietal lobe appears preserved, with no observable tissue loss - no evident atrophy or tissue thinning seen in the occipital lobe - mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) and posterior cingulate gyrus (mild atrophy on the left) For the subcortical structures: - basal forebrain maintains a normal appearance with no observable atrophic features - thalamus maintains a normal appearance with no observable atrophic features - no clear atrophic alterations are visible in the pallidum - ventral dc appears preserved, with no observable tissue loss - mild atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens - moderate bilateral atrophy of the amygdala - caudate maintains a normal appearance with no observable atrophic features - mild atrophy of the left hippocampus - mild-to-moderate atrophy of the right hippocampus - putamen appears within normal limits without apparent atrophy
AD
ADNI_006_S_6770_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_20210903135418788_210_S1059447_I1488072
On a T1-weighted brain MRI we observed: For the subcortical structures: - no appreciable degenerative or atrophic changes observed in the accumbens - pallidum maintains a normal appearance with no observable atrophic features - no findings suggestive of atrophy are seen in the basal forebrain - amygdala demonstrates a healthy morphology without signs of atrophy - no evident atrophy or tissue thinning seen in the thalamus - no findings suggestive of atrophy are seen in the ventral dc - no clear atrophic alterations are visible in the hippocampus - no observable atrophic changes in the putamen - caudate maintains a normal appearance with no observable atrophic features For the ventricles: - mild-to-moderate enlargement of the 4th ventricle - no evident size increase noted in the external csf - mild enlargement of the right inf. lateral ventricle; normal-to-mild enlargement of the left inf. lateral ventricle - lateral ventricle appears to be of normal dimensions, with no observable increase in size - no appreciable enlargement noted in the 3rd ventricle For the cerebral cortex: - no findings suggestive of atrophy are seen in the frontal lobe - no findings suggestive of atrophy are seen in the temporal lobe - limbic cortex appears within normal limits without apparent atrophy - no appreciable degenerative or atrophic changes observed in the parietal lobe - no observable atrophic changes in the occipital lobe - no clear atrophic alterations are visible in the insular cortex
AD
FTLD_203290737_03739_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10451122
On a T1-weighted brain MRI we observed: For the ventricles: - 4th ventricle maintains its expected proportions without signs of enlargement - severe enlargement of the left inf. lateral ventricle and mild-to-moderate enlargement of the right inf. lateral ventricle - mild-to-moderate enlargement of the left lateral ventricle and mild enlargement of the right lateral ventricle - 3rd ventricle appears within normal size limits with no apparent enlargement - mild enlargement of the external csf For the subcortical structures: - mild atrophy of the left thalamus; the right thalamus is normal - mild bilateral atrophy of the accumbens - no evident atrophy or tissue thinning seen in the basal forebrain - mild-to-moderate atrophy of the left pallidum; normal-to-mild atrophy of the right pallidum - no appreciable degenerative or atrophic changes observed in the ventral dc - severe atrophy of the left amygdala and moderate atrophy of the right amygdala - mild-to-moderate atrophy of the left putamen; the right putamen is normal - mild atrophy of the left caudate; the right caudate is normal - moderate-to-severe atrophy of the left hippocampus - the left hippocampus volume is borderline low For the cerebral cortex: - mild-to-moderate atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and mild atrophy on the right), posterior insula (moderate atrophy on the left and mild-to-moderate atrophy on the right) and central operculum (mild atrophy on the left) - no findings suggestive of atrophy are seen in the occipital lobe - mild atrophy of the left limbic cortex; normal-to-mild atrophy of the right limbic cortex; focal volume loss observed in the following subregions: entorhinal area (mild-to-moderate atrophy both left/right) and parahippocampal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) - severe atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (severe atrophy on the left and mild atrophy on the right), inf. temporal gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), planum polare (mild atrophy both left/right), middle temporal gyrus (moderate atrophy on the left), fusiform gyrus (mild-to-moderate atrophy on the left and normal on the right) and sup. temporal gyrus (mild atrophy on the left) - parietal lobe maintains a normal appearance with no observable atrophic features - frontal lobe appears within normal limits without apparent atrophy
SV
FTLD_203423634_03432_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450731
On a T1-weighted brain MRI we observed: For the ventricles: - mild enlargement of the 4th ventricle - mild enlargement of the 3rd ventricle - no evident size increase noted in the inf. lateral ventricle - no clear enlargement or abnormal growth seen in the external csf - no findings suggestive of enlargement are seen in the lateral ventricle For the cerebral cortex: - no findings suggestive of atrophy are seen in the limbic cortex - no findings suggestive of atrophy are seen in the occipital lobe - the temporal lobe shows no notable changes suggestive of atrophy - mild atrophy of the right parietal lobe; normal-to-mild atrophy of the left parietal lobe; focal volume loss observed in the following subregions: supramarginal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), angular gyrus (normal on the left and mild atrophy on the right) and precuneus (mild atrophy on the left and normal on the right) - no findings suggestive of atrophy are seen in the insular cortex - mild bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: precentral gyrus (mild atrophy both left/right), medial orbital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), sup. frontal gyrus (normal on the left and mild-to-moderate atrophy on the right), supplementary motor cortex (mild atrophy on the left and normal-to-mild atrophy on the right) and middle frontal gyrus (mild atrophy on the left) For the subcortical structures: - no observable atrophic changes in the pallidum - ventral dc appears preserved, with no observable tissue loss - amygdala appears within normal limits without apparent atrophy - no findings suggestive of atrophy are seen in the caudate - no findings suggestive of atrophy are seen in the putamen - the thalamus shows no notable changes suggestive of atrophy - accumbens demonstrates a healthy morphology without signs of atrophy - hippocampus appears preserved, with no observable tissue loss - no observable atrophic changes in the basal forebrain
PNFA
ADNI_130_S_4589_MR_MPRAGE_br_raw_20120321091622292_155_S144262_I291219
On a T1-weighted brain MRI we observed: For the ventricles: - the 4th ventricle shows no notable changes suggestive of enlargement - 3rd ventricle maintains a typical volume without observable enlargement - lateral ventricle maintains a typical volume without observable enlargement - external csf maintains a typical volume without observable enlargement - inf. lateral ventricle maintains a typical volume without observable enlargement For the cerebral cortex: - frontal lobe demonstrates a healthy morphology without signs of atrophy - mild bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: inf. temporal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), transverse temporal gyrus (mild atrophy on the right) and middle temporal gyrus (mild atrophy on the left and normal on the right) - no clear atrophic alterations are visible in the insular cortex - limbic cortex appears preserved, with no observable tissue loss - mild atrophy of the left parietal lobe and mild-to-moderate atrophy of the right parietal lobe; focal volume loss observed in the following subregions: supramarginal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), angular gyrus (mild atrophy on the left and normal on the right), postcentral gyrus medial segment (normal on the left and mild atrophy on the right) and precuneus (normal on the left and mild atrophy on the right) - occipital lobe appears within normal limits without apparent atrophy For the subcortical structures: - accumbens demonstrates a healthy morphology without signs of atrophy - no evident atrophy or tissue thinning seen in the hippocampus - caudate appears preserved, with no observable tissue loss - no evident atrophy or tissue thinning seen in the ventral dc - mild-to-moderate atrophy of the left amygdala and moderate atrophy of the right amygdala - no observable atrophic changes in the putamen - basal forebrain appears within normal limits without apparent atrophy - pallidum appears within normal limits without apparent atrophy - no clear atrophic alterations are visible in the thalamus
AD
FTLD_203628476_03672_MR_Accelerated_Sagittal_IR-FSPGR_br_raw_202_I10451045
On a T1-weighted brain MRI we observed: For the subcortical structures: - moderate atrophy of the left caudate and mild-to-moderate atrophy of the right caudate - basal forebrain maintains a normal appearance with no observable atrophic features - mild atrophy of the right amygdala; normal-to-mild atrophy of the left amygdala - mild-to-moderate atrophy of the left putamen and mild atrophy of the right putamen - the left hippocampus volume is borderline low - the left hippocampus volume is borderline low - mild-to-moderate atrophy of the left thalamus and mild atrophy of the right thalamus - moderate atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens - mild-to-moderate atrophy of the left ventral dc and mild atrophy of the right ventral dc - moderate-to-severe atrophy of the left pallidum and mild atrophy of the right pallidum For the ventricles: - mild enlargement of the external csf - mild-to-moderate enlargement of the 3rd ventricle - 4th ventricle appears to be of normal dimensions, with no observable increase in size - mild-to-moderate enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle - mild-to-moderate bilateral enlargement of the lateral ventricle For the cerebral cortex: - mild atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: sup. temporal gyrus (mild atrophy on the left), planum temporale (moderate atrophy on the left and normal on the right), transverse temporal gyrus (mild atrophy on the left) and temporal pole (mild atrophy on the left and normal on the right) - occipital lobe appears within normal limits without apparent atrophy - frontal lobe demonstrates a healthy morphology without signs of atrophy - the insular cortex shows no notable changes suggestive of atrophy - mild atrophy of the left parietal lobe; the right parietal lobe is normal - the limbic cortex shows no notable changes suggestive of atrophy
PNFA
FTLD_203932722_03223_MR_Accelerated_Sagittal_MPRAGE_br_raw_20241_I11047338
On a T1-weighted brain MRI we observed: For the ventricles: - mild bilateral enlargement of the inf. lateral ventricle - no appreciable enlargement noted in the 4th ventricle - moderate-to-severe enlargement of the external csf - mild enlargement of the left lateral ventricle and mild-to-moderate enlargement of the right lateral ventricle - no clear enlargement or abnormal growth seen in the 3rd ventricle For the subcortical structures: - mild bilateral atrophy of the ventral dc - moderate bilateral atrophy of the pallidum - mild-to-moderate atrophy of the left accumbens and moderate-to-severe atrophy of the right accumbens - moderate-to-severe atrophy of the left thalamus and moderate atrophy of the right thalamus - no evident atrophy or tissue thinning seen in the basal forebrain - moderate atrophy of the left caudate and moderate-to-severe atrophy of the right caudate - mild bilateral atrophy of the amygdala - mild atrophy of the left hippocampus - mild atrophy of the right hippocampus - severe bilateral atrophy of the putamen For the cerebral cortex: - no appreciable degenerative or atrophic changes observed in the insular cortex - mild atrophy of the left frontal lobe; normal-to-mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: frontal pole (mild atrophy on the left and mild-to-moderate atrophy on the right), gyrus rectus (mild atrophy on the left and normal on the right), anterior orbital gyrus (mild atrophy on the right) and medial orbital gyrus (mild atrophy on the left) - occipital lobe appears within normal limits without apparent atrophy - no clear atrophic alterations are visible in the limbic cortex - mild-to-moderate atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: middle temporal gyrus (mild-to-moderate atrophy both left/right), sup. temporal gyrus (mild atrophy both left/right), planum temporale (mild atrophy on the left and normal-to-mild atrophy on the right) and temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right) - parietal lobe maintains a normal appearance with no observable atrophic features
BV
ADNI_098_S_10543_MR_Accelerated_Sagittal_MPRAGE_MSV22_br_raw_20250317190723888_1_I11158421
On a T1-weighted brain MRI we observed: For the ventricles: - no evident size increase noted in the external csf - inf. lateral ventricle maintains a typical volume without observable enlargement - no appreciable enlargement noted in the lateral ventricle - no observable enlargement of the 4th ventricle - 3rd ventricle appears within normal size limits with no apparent enlargement For the cerebral cortex: - no appreciable degenerative or atrophic changes observed in the insular cortex - occipital lobe maintains a normal appearance with no observable atrophic features - no observable atrophic changes in the limbic cortex - no appreciable degenerative or atrophic changes observed in the temporal lobe - no observable atrophic changes in the parietal lobe - frontal lobe demonstrates a healthy morphology without signs of atrophy For the subcortical structures: - the hippocampus shows no notable changes suggestive of atrophy - no evident atrophy or tissue thinning seen in the putamen - no findings suggestive of atrophy are seen in the ventral dc - pallidum appears preserved, with no observable tissue loss - the thalamus shows no notable changes suggestive of atrophy - no evident atrophy or tissue thinning seen in the amygdala - no appreciable degenerative or atrophic changes observed in the accumbens - the caudate shows no notable changes suggestive of atrophy - mild atrophy of the right basal forebrain; the left basal forebrain is normal
CN
FTLD_203979630_03037_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10176924
On a T1-weighted brain MRI we observed: For the subcortical structures: - moderate atrophy of the left putamen and moderate-to-severe atrophy of the right putamen - basal forebrain maintains a normal appearance with no observable atrophic features - mild atrophy of the left pallidum and mild-to-moderate atrophy of the right pallidum - severe bilateral atrophy of the amygdala - ventral dc maintains a normal appearance with no observable atrophic features - moderate atrophy of the left accumbens and moderate-to-severe atrophy of the right accumbens - moderate-to-severe atrophy of the left hippocampus - severe atrophy of the right hippocampus - mild bilateral atrophy of the caudate - no observable atrophic changes in the thalamus For the cerebral cortex: - mild-to-moderate bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: entorhinal area (mild-to-moderate atrophy both left/right), parahippocampal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right) and posterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) - no clear atrophic alterations are visible in the frontal lobe - mild-to-moderate atrophy of the left temporal lobe and moderate-to-severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (mild-to-moderate atrophy on the left and moderate atrophy on the right), inf. temporal gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), sup. temporal gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), planum temporale (normal-to-mild atrophy on the left and mild atrophy on the right), transverse temporal gyrus (mild atrophy on the left), fusiform gyrus (normal on the left and mild atrophy on the right) and middle temporal gyrus (normal on the left and mild atrophy on the right) - no observable atrophic changes in the parietal lobe - mild bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: posterior insula (mild-to-moderate atrophy on the left and moderate-to-severe atrophy on the right) and anterior insula (mild atrophy on the left and mild-to-moderate atrophy on the right) - occipital lobe maintains a normal appearance with no observable atrophic features For the ventricles: - severe bilateral enlargement of the inf. lateral ventricle - 4th ventricle maintains its expected proportions without signs of enlargement - mild-to-moderate enlargement of the 3rd ventricle - no observable enlargement of the external csf - mild-to-moderate bilateral enlargement of the lateral ventricle
BV
ADNI_010_S_10871_MR_Accelerated_Sagittal_MPRAGE_MSV22_br_raw_20250815190049460_1_I11416330
On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: inf. temporal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and planum temporale (mild atrophy on the left and normal on the right) - occipital lobe demonstrates a healthy morphology without signs of atrophy - mild atrophy of the right parietal lobe; normal-to-mild atrophy of the left parietal lobe; focal volume loss observed in the following subregions: precuneus (mild atrophy both left/right) - mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: parietal operculum (mild-to-moderate atrophy on the left and normal on the right) - limbic cortex appears within normal limits without apparent atrophy - frontal lobe maintains a normal appearance with no observable atrophic features For the subcortical structures: - no findings suggestive of atrophy are seen in the basal forebrain - no observable atrophic changes in the pallidum - putamen appears within normal limits without apparent atrophy - accumbens appears within normal limits without apparent atrophy - thalamus maintains a normal appearance with no observable atrophic features - no findings suggestive of atrophy are seen in the hippocampus - no evident atrophy or tissue thinning seen in the ventral dc - mild atrophy of the right caudate; normal-to-mild atrophy of the left caudate - mild bilateral atrophy of the amygdala For the ventricles: - lateral ventricle maintains a typical volume without observable enlargement - no appreciable enlargement noted in the 3rd ventricle - mild enlargement of the external csf - no evident size increase noted in the 4th ventricle - inf. lateral ventricle appears to be of normal dimensions, with no observable increase in size
AD
FTLD_203799061_03169_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10177105
On a T1-weighted brain MRI we observed: For the ventricles: - no clear enlargement or abnormal growth seen in the 3rd ventricle - no findings suggestive of enlargement are seen in the lateral ventricle - no clear enlargement or abnormal growth seen in the inf. lateral ventricle - 4th ventricle appears to be of normal dimensions, with no observable increase in size - external csf maintains its expected proportions without signs of enlargement For the cerebral cortex: - frontal lobe appears within normal limits without apparent atrophy - occipital lobe demonstrates a healthy morphology without signs of atrophy - no evident atrophy or tissue thinning seen in the limbic cortex - no appreciable degenerative or atrophic changes observed in the parietal lobe - no clear atrophic alterations are visible in the temporal lobe - insular cortex demonstrates a healthy morphology without signs of atrophy For the subcortical structures: - accumbens appears preserved, with no observable tissue loss - hippocampus appears within normal limits without apparent atrophy - amygdala appears preserved, with no observable tissue loss - no clear atrophic alterations are visible in the ventral dc - the basal forebrain shows no notable changes suggestive of atrophy - no findings suggestive of atrophy are seen in the thalamus - no findings suggestive of atrophy are seen in the pallidum - no findings suggestive of atrophy are seen in the putamen - no evident atrophy or tissue thinning seen in the caudate
CN
ADNI_027_S_0404_MR_MPR__GradWarp__B1_Correction__N3__Scaled_Br_20061222194841960_S13866_I34204
On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) and posterior cingulate gyrus (mild atrophy on the left) - occipital lobe appears within normal limits without apparent atrophy - no clear atrophic alterations are visible in the frontal lobe - no appreciable degenerative or atrophic changes observed in the parietal lobe - insular cortex appears preserved, with no observable tissue loss - mild-to-moderate atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: temporal pole (moderate atrophy on the left and mild-to-moderate atrophy on the right), middle temporal gyrus (mild-to-moderate atrophy on the left) and sup. temporal gyrus (mild atrophy on the right) For the subcortical structures: - moderate bilateral atrophy of the amygdala - no evident atrophy or tissue thinning seen in the putamen - mild atrophy of the left hippocampus - mild-to-moderate atrophy of the right hippocampus - mild atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens - basal forebrain demonstrates a healthy morphology without signs of atrophy - no observable atrophic changes in the pallidum - caudate maintains a normal appearance with no observable atrophic features - no observable atrophic changes in the thalamus - ventral dc maintains a normal appearance with no observable atrophic features For the ventricles: - mild enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal - lateral ventricle maintains a typical volume without observable enlargement - 4th ventricle appears to be of normal dimensions, with no observable increase in size - no clear enlargement or abnormal growth seen in the 3rd ventricle - the external csf shows no notable changes suggestive of enlargement
AD
FTLD_203411700_03001_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450139
On a T1-weighted brain MRI we observed: For the subcortical structures: - no findings suggestive of atrophy are seen in the accumbens - the hippocampus shows no notable changes suggestive of atrophy - pallidum maintains a normal appearance with no observable atrophic features - mild atrophy of the right putamen; normal-to-mild atrophy of the left putamen - thalamus appears preserved, with no observable tissue loss - amygdala maintains a normal appearance with no observable atrophic features - no observable atrophic changes in the basal forebrain - ventral dc appears preserved, with no observable tissue loss - mild atrophy of the left caudate and mild-to-moderate atrophy of the right caudate For the cerebral cortex: - no appreciable degenerative or atrophic changes observed in the temporal lobe - no evident atrophy or tissue thinning seen in the occipital lobe - mild atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (normal on the left and mild atrophy on the right) - no appreciable degenerative or atrophic changes observed in the parietal lobe - no observable atrophic changes in the insular cortex - mild atrophy of the left frontal lobe and mild-to-moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (mild atrophy on the left and moderate atrophy on the right), medial orbital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), opercular inf. frontal gyrus (mild atrophy on the left and normal on the right) and posterior orbital gyrus (normal on the left and mild atrophy on the right) For the ventricles: - inf. lateral ventricle maintains its expected proportions without signs of enlargement - lateral ventricle maintains a typical volume without observable enlargement - no evident size increase noted in the 4th ventricle - mild enlargement of the external csf - 3rd ventricle appears to be of normal dimensions, with no observable increase in size
PNFA
FTLD_203705780_03080_MR_Accelerated_Sagittal_MPRAGE_br_raw_20241_I11047242
On a T1-weighted brain MRI we observed: For the ventricles: - mild enlargement of the 3rd ventricle - mild enlargement of the left lateral ventricle; the right lateral ventricle is normal - no evident size increase noted in the external csf - no evident size increase noted in the inf. lateral ventricle - moderate enlargement of the 4th ventricle For the cerebral cortex: - mild-to-moderate bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: temporal pole (mild atrophy on the left and mild-to-moderate atrophy on the right), sup. temporal gyrus (mild atrophy both left/right) and inf. temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) - no findings suggestive of atrophy are seen in the frontal lobe - insular cortex appears preserved, with no observable tissue loss - no observable atrophic changes in the parietal lobe - occipital lobe appears within normal limits without apparent atrophy - limbic cortex appears within normal limits without apparent atrophy For the subcortical structures: - accumbens appears within normal limits without apparent atrophy - no appreciable degenerative or atrophic changes observed in the putamen - mild bilateral atrophy of the amygdala - the ventral dc shows no notable changes suggestive of atrophy - no clear atrophic alterations are visible in the caudate - mild atrophy of the left hippocampus - mild atrophy of the right hippocampus - pallidum appears within normal limits without apparent atrophy - thalamus appears preserved, with no observable tissue loss - no appreciable degenerative or atrophic changes observed in the basal forebrain
PNFA
FTLD_203545403_03304_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10176941
On a T1-weighted brain MRI we observed: For the ventricles: - mild enlargement of the external csf - severe bilateral enlargement of the lateral ventricle - no evident size increase noted in the 4th ventricle - mild enlargement of the 3rd ventricle - severe bilateral enlargement of the inf. lateral ventricle For the cerebral cortex: - mild-to-moderate atrophy of the left insular cortex and moderate atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and severe atrophy on the right), posterior insula (mild-to-moderate atrophy both left/right) and frontal operculum (normal-to-mild atrophy on the left and mild atrophy on the right) - moderate bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: entorhinal area (mild-to-moderate atrophy on the left and moderate atrophy on the right), anterior cingulate gyrus (mild-to-moderate atrophy both left/right) and parahippocampal gyrus (mild-to-moderate atrophy both left/right) - occipital lobe maintains a normal appearance with no observable atrophic features - no evident atrophy or tissue thinning seen in the parietal lobe - mild-to-moderate atrophy of the right temporal lobe; the left temporal lobe is normal; focal volume loss observed in the following subregions: temporal pole (mild atrophy on the left and moderate atrophy on the right) and inf. temporal gyrus (normal on the left and mild atrophy on the right) - moderate atrophy of the right frontal lobe; normal-to-mild atrophy of the left frontal lobe; focal volume loss observed in the following subregions: sup. frontal gyrus medial segment (mild atrophy on the left and mild-to-moderate atrophy on the right), medial frontal cortex (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), medial orbital gyrus (mild atrophy both left/right), gyrus rectus (mild atrophy both left/right), triangular inf. frontal gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), opercular inf. frontal gyrus (normal on the left and mild-to-moderate atrophy on the right), posterior orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. frontal gyrus (normal on the left and mild atrophy on the right) and lateral orbital gyrus (mild atrophy on the left and normal on the right) For the subcortical structures: - no evident atrophy or tissue thinning seen in the basal forebrain - severe bilateral atrophy of the putamen - severe bilateral atrophy of the accumbens - moderate atrophy of the left pallidum and severe atrophy of the right pallidum - mild-to-moderate atrophy of the right thalamus; normal-to-mild atrophy of the left thalamus - moderate-to-severe atrophy of the left hippocampus - severe atrophy of the right hippocampus - moderate-to-severe atrophy of the left amygdala and severe atrophy of the right amygdala - severe bilateral atrophy of the caudate - mild atrophy of the right ventral dc; normal-to-mild atrophy of the left ventral dc
BV
FTLD_203107266_02660_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177776
On a T1-weighted brain MRI we observed: For the subcortical structures: - moderate atrophy of the left hippocampus - moderate atrophy of the left putamen; the right putamen is normal - mild-to-moderate atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens - basal forebrain appears within normal limits without apparent atrophy - no observable atrophic changes in the ventral dc - severe atrophy of the left amygdala and moderate-to-severe atrophy of the right amygdala - the thalamus shows no notable changes suggestive of atrophy - pallidum maintains a normal appearance with no observable atrophic features - no appreciable degenerative or atrophic changes observed in the caudate For the ventricles: - severe enlargement of the left inf. lateral ventricle and moderate enlargement of the right inf. lateral ventricle - mild enlargement of the left lateral ventricle; normal-to-mild enlargement of the right lateral ventricle - no findings suggestive of enlargement are seen in the 4th ventricle - mild-to-moderate enlargement of the 3rd ventricle - mild-to-moderate enlargement of the external csf For the cerebral cortex: - no appreciable degenerative or atrophic changes observed in the frontal lobe - moderate-to-severe atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (moderate-to-severe atrophy on the left and mild atrophy on the right), anterior cingulate gyrus (moderate atrophy on the left and normal-to-mild atrophy on the right) and parahippocampal gyrus (moderate atrophy on the left and normal on the right) - occipital lobe appears within normal limits without apparent atrophy - severe atrophy of the left temporal lobe and moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (severe atrophy on the left and moderate atrophy on the right), sup. temporal gyrus (moderate-to-severe atrophy on the left and mild atrophy on the right), inf. temporal gyrus (mild-to-moderate atrophy both left/right), planum polare (moderate-to-severe atrophy on the left and normal on the right), fusiform gyrus (mild atrophy both left/right), middle temporal gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), planum temporale (mild-to-moderate atrophy on the left and normal on the right) and transverse temporal gyrus (mild atrophy on the left and normal on the right) - no observable atrophic changes in the parietal lobe - severe atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: posterior insula (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), anterior insula (severe atrophy on the left and normal on the right), central operculum (mild atrophy on the left and normal-to-mild atrophy on the right), frontal operculum (mild-to-moderate atrophy on the left) and parietal operculum (mild atrophy on the left)
SV
FTLD_203888981_02188_MR_Sagittal_MP-Rage_br_raw_20230206184523694_I10182636
On a T1-weighted brain MRI we observed: For the ventricles: - moderate enlargement of the left lateral ventricle and mild-to-moderate enlargement of the right lateral ventricle - severe bilateral enlargement of the inf. lateral ventricle - the 3rd ventricle shows no notable changes suggestive of enlargement - no appreciable enlargement noted in the 4th ventricle - no findings suggestive of enlargement are seen in the external csf For the cerebral cortex: - mild atrophy of the right limbic cortex; normal-to-mild atrophy of the left limbic cortex; focal volume loss observed in the following subregions: parahippocampal gyrus (mild atrophy both left/right) - no observable atrophic changes in the insular cortex - parietal lobe appears preserved, with no observable tissue loss - no findings suggestive of atrophy are seen in the frontal lobe - mild atrophy of the left temporal lobe and mild-to-moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: middle temporal gyrus (mild atrophy on the left and moderate atrophy on the right), transverse temporal gyrus (mild atrophy on the left and normal on the right) and temporal pole (normal on the left and mild atrophy on the right) - no evident atrophy or tissue thinning seen in the occipital lobe For the subcortical structures: - mild-to-moderate bilateral atrophy of the caudate - mild atrophy of the left pallidum and mild-to-moderate atrophy of the right pallidum - the amygdala shows no notable changes suggestive of atrophy - thalamus maintains a normal appearance with no observable atrophic features - mild-to-moderate atrophy of the left hippocampus - mild-to-moderate atrophy of the right hippocampus - moderate-to-severe atrophy of the left putamen and moderate atrophy of the right putamen - mild bilateral atrophy of the accumbens - the ventral dc shows no notable changes suggestive of atrophy - the basal forebrain shows no notable changes suggestive of atrophy
BV
FTLD_203916466_03661_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10451034
On a T1-weighted brain MRI we observed: For the cerebral cortex: - temporal lobe appears within normal limits without apparent atrophy - no clear atrophic alterations are visible in the occipital lobe - parietal lobe appears preserved, with no observable tissue loss - mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left) and posterior insula (mild atrophy on the left and normal on the right) - no appreciable degenerative or atrophic changes observed in the limbic cortex - no findings suggestive of atrophy are seen in the frontal lobe For the subcortical structures: - the putamen shows no notable changes suggestive of atrophy - mild atrophy of the left pallidum; the right pallidum is normal - mild atrophy of the left hippocampus - mild-to-moderate atrophy of the left amygdala and mild atrophy of the right amygdala - no observable atrophic changes in the accumbens - the caudate shows no notable changes suggestive of atrophy - mild atrophy of the left ventral dc; the right ventral dc is normal - mild atrophy of the left thalamus; the right thalamus is normal - no observable atrophic changes in the basal forebrain For the ventricles: - no clear enlargement or abnormal growth seen in the 3rd ventricle - no findings suggestive of enlargement are seen in the external csf - mild enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal - 4th ventricle maintains its expected proportions without signs of enlargement - lateral ventricle appears within normal size limits with no apparent enlargement
PNFA
ADNI_052_S_10284_MR_Accelerated_Sagittal_MPRAGE_MSV21_br_raw_20241021192547871_1_I10985640
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no findings suggestive of atrophy are seen in the parietal lobe - the insular cortex shows no notable changes suggestive of atrophy - temporal lobe demonstrates a healthy morphology without signs of atrophy - moderate bilateral atrophy of the occipital lobe; focal volume loss observed in the following subregions: calcarine cortex (mild-to-moderate atrophy both left/right), inf. occipital gyrus (mild atrophy both left/right), cuneus (mild atrophy on the left and normal-to-mild atrophy on the right), middle occipital gyrus (mild atrophy on the left), sup. occipital gyrus (normal on the left and mild atrophy on the right) and occipital fusiform gyrus (normal on the left and mild atrophy on the right) - limbic cortex appears within normal limits without apparent atrophy - no evident atrophy or tissue thinning seen in the frontal lobe For the ventricles: - 3rd ventricle appears to be of normal dimensions, with no observable increase in size - external csf maintains a typical volume without observable enlargement - inf. lateral ventricle appears to be of normal dimensions, with no observable increase in size - 4th ventricle maintains its expected proportions without signs of enlargement - lateral ventricle appears to be of normal dimensions, with no observable increase in size For the subcortical structures: - the putamen shows no notable changes suggestive of atrophy - thalamus maintains a normal appearance with no observable atrophic features - no evident atrophy or tissue thinning seen in the pallidum - hippocampus appears within normal limits without apparent atrophy - no evident atrophy or tissue thinning seen in the ventral dc - accumbens appears preserved, with no observable tissue loss - basal forebrain maintains a normal appearance with no observable atrophic features - amygdala appears within normal limits without apparent atrophy - no observable atrophic changes in the caudate
CN
FTLD_203011672_03271_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177308
On a T1-weighted brain MRI we observed: For the ventricles: - mild enlargement of the external csf - severe enlargement of the left inf. lateral ventricle and moderate enlargement of the right inf. lateral ventricle - the 4th ventricle shows no notable changes suggestive of enlargement - moderate enlargement of the left lateral ventricle and mild enlargement of the right lateral ventricle - moderate enlargement of the 3rd ventricle For the cerebral cortex: - severe atrophy of the left temporal lobe and moderate-to-severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (severe atrophy on the left and moderate-to-severe atrophy on the right), inf. temporal gyrus (mild-to-moderate atrophy on the left and moderate atrophy on the right), middle temporal gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), planum polare (mild atrophy both left/right), sup. temporal gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) and fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) - mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (moderate atrophy on the left and mild-to-moderate atrophy on the right) and parahippocampal gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right) - mild atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: triangular inf. frontal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), gyrus rectus (mild atrophy both left/right), supplementary motor cortex (normal-to-mild atrophy on the left and mild atrophy on the right), medial orbital gyrus (mild atrophy on the left and normal on the right) and posterior orbital gyrus (normal on the left and mild atrophy on the right) - moderate atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), posterior insula (mild-to-moderate atrophy on the left and mild atrophy on the right) and central operculum (mild atrophy on the left and normal on the right) - no observable atrophic changes in the occipital lobe - no clear atrophic alterations are visible in the parietal lobe For the subcortical structures: - no appreciable degenerative or atrophic changes observed in the ventral dc - severe bilateral atrophy of the amygdala - basal forebrain appears within normal limits without apparent atrophy - mild-to-moderate atrophy of the left pallidum; normal-to-mild atrophy of the right pallidum - the thalamus shows no notable changes suggestive of atrophy - moderate-to-severe atrophy of the left hippocampus - moderate atrophy of the right hippocampus - mild-to-moderate atrophy of the left caudate and mild atrophy of the right caudate - severe atrophy of the left putamen and moderate atrophy of the right putamen - moderate-to-severe atrophy of the left accumbens and mild atrophy of the right accumbens
SV
ADNI_098_S_4002_MR_Accelerated_Sag_IR-SPGR__br_raw_20110301150635678_160_S100612_I221789
On a T1-weighted brain MRI we observed: For the cerebral cortex: - the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in lateral orbital gyrus (moderate atrophy on the right), posterior orbital gyrus (mild atrophy on the left), medial frontal cortex (mild atrophy on the left and normal on the right) and precentral gyrus medial segment (normal on the left and mild atrophy on the right) - the insular cortex shows no notable changes suggestive of atrophy - mild-to-moderate atrophy of the right temporal lobe; normal-to-mild atrophy of the left temporal lobe; focal volume loss observed in the following subregions: fusiform gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), middle temporal gyrus (mild atrophy on the right) and sup. temporal gyrus (normal on the left and mild atrophy on the right) - mild-to-moderate atrophy of the left parietal lobe and mild atrophy of the right parietal lobe; focal volume loss observed in the following subregions: postcentral gyrus (normal on the left and mild atrophy on the right), angular gyrus (mild atrophy on the left and normal on the right), postcentral gyrus medial segment (normal on the left and mild atrophy on the right) and sup. parietal lobule (mild atrophy on the left) - no appreciable degenerative or atrophic changes observed in the occipital lobe - mild atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (normal on the left and mild atrophy on the right) For the subcortical structures: - amygdala demonstrates a healthy morphology without signs of atrophy - mild bilateral atrophy of the accumbens - the basal forebrain shows no notable changes suggestive of atrophy - no evident atrophy or tissue thinning seen in the pallidum - no observable atrophic changes in the caudate - no findings suggestive of atrophy are seen in the putamen - mild atrophy of the right hippocampus - ventral dc maintains a normal appearance with no observable atrophic features - no clear atrophic alterations are visible in the thalamus For the ventricles: - no findings suggestive of enlargement are seen in the lateral ventricle - no clear enlargement or abnormal growth seen in the 3rd ventricle - 4th ventricle appears to be of normal dimensions, with no observable increase in size - mild-to-moderate enlargement of the external csf - inf. lateral ventricle maintains a typical volume without observable enlargement
CN
ADNI_305_S_6881_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_20200825165730443_1_S953745_I1330894
On a T1-weighted brain MRI we observed: For the ventricles: - mild enlargement of the 3rd ventricle - mild-to-moderate enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle - mild-to-moderate enlargement of the 4th ventricle - moderate bilateral enlargement of the lateral ventricle - the external csf shows no notable changes suggestive of enlargement For the subcortical structures: - no observable atrophic changes in the basal forebrain - no findings suggestive of atrophy are seen in the caudate - mild-to-moderate atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens - no evident atrophy or tissue thinning seen in the thalamus - pallidum appears preserved, with no observable tissue loss - no evident atrophy or tissue thinning seen in the amygdala - the left hippocampus volume is borderline low - mild atrophy of the right hippocampus - no clear atrophic alterations are visible in the putamen - no observable atrophic changes in the ventral dc For the cerebral cortex: - no clear atrophic alterations are visible in the occipital lobe - frontal lobe appears within normal limits without apparent atrophy - mild-to-moderate bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: inf. temporal gyrus (mild atrophy both left/right), temporal pole (mild atrophy both left/right) and transverse temporal gyrus (mild-to-moderate atrophy on the left and normal on the right) - parietal lobe demonstrates a healthy morphology without signs of atrophy - mild-to-moderate atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: central operculum (mild-to-moderate atrophy both left/right) and parietal operculum (mild atrophy on the left and normal on the right) - no clear atrophic alterations are visible in the limbic cortex
AD
FTLD_203833156_02653_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178165
On a T1-weighted brain MRI we observed: For the ventricles: - no observable enlargement of the 4th ventricle - no findings suggestive of enlargement are seen in the lateral ventricle - no evident size increase noted in the 3rd ventricle - mild enlargement of the external csf - severe enlargement of the left inf. lateral ventricle and mild-to-moderate enlargement of the right inf. lateral ventricle For the cerebral cortex: - mild atrophy of the right limbic cortex; normal-to-mild atrophy of the left limbic cortex; focal volume loss observed in the following subregions: entorhinal area (mild-to-moderate atrophy on the left and mild atrophy on the right) and parahippocampal gyrus (mild atrophy both left/right) - parietal lobe appears preserved, with no observable tissue loss - no evident atrophy or tissue thinning seen in the frontal lobe - severe atrophy of the left temporal lobe and mild-to-moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), middle temporal gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), fusiform gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), planum temporale (normal-to-mild atrophy on the left and mild atrophy on the right), inf. temporal gyrus (mild-to-moderate atrophy on the left and normal on the right) and sup. temporal gyrus (mild-to-moderate atrophy on the left and normal on the right) - mild-to-moderate bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), posterior insula (moderate atrophy on the left and mild-to-moderate atrophy on the right), central operculum (mild atrophy on the right) and parietal operculum (normal on the left and mild atrophy on the right) - occipital lobe appears preserved, with no observable tissue loss For the subcortical structures: - no clear atrophic alterations are visible in the thalamus - no findings suggestive of atrophy are seen in the pallidum - no appreciable degenerative or atrophic changes observed in the basal forebrain - severe atrophy of the left amygdala and moderate-to-severe atrophy of the right amygdala - no findings suggestive of atrophy are seen in the caudate - no evident atrophy or tissue thinning seen in the ventral dc - mild-to-moderate atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens - mild-to-moderate atrophy of the left putamen; the right putamen is normal - mild-to-moderate atrophy of the left hippocampus - the left hippocampus volume is borderline low
SV
FTLD_203933841_02143_MR_Sagittal_MP-Rage_br_raw_20230124205938681_I10178482
On a T1-weighted brain MRI we observed: For the ventricles: - severe enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal - mild enlargement of the 3rd ventricle - mild enlargement of the external csf - the 4th ventricle shows no notable changes suggestive of enlargement - moderate-to-severe enlargement of the left lateral ventricle and mild enlargement of the right lateral ventricle For the cerebral cortex: - severe atrophy of the left frontal lobe and mild-to-moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: gyrus rectus (moderate atrophy on the left and mild-to-moderate atrophy on the right), medial orbital gyrus (moderate atrophy on the left and mild atrophy on the right), sup. frontal gyrus medial segment (moderate atrophy on the left and mild atrophy on the right), frontal pole (mild-to-moderate atrophy both left/right), triangular inf. frontal gyrus (mild-to-moderate atrophy both left/right), sup. frontal gyrus (moderate-to-severe atrophy on the left and normal-to-mild atrophy on the right), precentral gyrus medial segment (mild atrophy on the right), medial frontal cortex (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), posterior orbital gyrus (mild atrophy both left/right), opercular inf. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), middle frontal gyrus (mild-to-moderate atrophy on the left and normal on the right), lateral orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and supplementary motor cortex (mild atrophy on the left and normal on the right) - moderate atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and mild atrophy on the right), central operculum (mild atrophy on the left and normal-to-mild atrophy on the right) and frontal operculum (mild atrophy on the left and normal-to-mild atrophy on the right) - parietal lobe appears within normal limits without apparent atrophy - moderate-to-severe atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: temporal pole (moderate atrophy on the left and normal-to-mild atrophy on the right), fusiform gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), middle temporal gyrus (mild atrophy on the left) and inf. temporal gyrus (mild atrophy on the left) - mild-to-moderate atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (moderate atrophy on the left and mild atrophy on the right) and parahippocampal gyrus (mild atrophy on the left) - no findings suggestive of atrophy are seen in the occipital lobe For the subcortical structures: - severe atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens - moderate atrophy of the left caudate; the right caudate is normal - the left hippocampus volume is borderline low - basal forebrain maintains a normal appearance with no observable atrophic features - mild-to-moderate atrophy of the left putamen; the right putamen is normal - no observable atrophic changes in the ventral dc - severe atrophy of the left amygdala; the right amygdala is normal - thalamus maintains a normal appearance with no observable atrophic features - pallidum appears within normal limits without apparent atrophy
BV
ADNI_002_S_0619_MR_MPR-R__GradWarp__N3__Scaled_Br_20070411125458928_S15145_I48617
On a T1-weighted brain MRI we observed: For the ventricles: - mild-to-moderate enlargement of the left inf. lateral ventricle and moderate enlargement of the right inf. lateral ventricle - moderate enlargement of the external csf - 4th ventricle appears within normal size limits with no apparent enlargement - moderate enlargement of the left lateral ventricle and mild-to-moderate enlargement of the right lateral ventricle - moderate enlargement of the 3rd ventricle For the subcortical structures: - moderate atrophy of the left hippocampus - moderate-to-severe atrophy of the right hippocampus - mild-to-moderate atrophy of the left ventral dc; normal-to-mild atrophy of the right ventral dc - moderate atrophy of the left caudate and moderate-to-severe atrophy of the right caudate - basal forebrain demonstrates a healthy morphology without signs of atrophy - mild-to-moderate bilateral atrophy of the thalamus - mild atrophy of the left pallidum and mild-to-moderate atrophy of the right pallidum - mild-to-moderate atrophy of the left putamen and moderate atrophy of the right putamen - moderate-to-severe atrophy of the left amygdala and severe atrophy of the right amygdala - mild-to-moderate atrophy of the left accumbens and moderate atrophy of the right accumbens For the cerebral cortex: - mild bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: triangular inf. frontal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), medial frontal cortex (mild atrophy both left/right), frontal pole (mild atrophy on the left and normal-to-mild atrophy on the right), gyrus rectus (normal-to-mild atrophy on the left and mild atrophy on the right) and supplementary motor cortex (mild-to-moderate atrophy on the left and normal on the right) - mild atrophy of the left temporal lobe and mild-to-moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (mild atrophy on the left and mild-to-moderate atrophy on the right), middle temporal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and inf. temporal gyrus (normal on the left and mild atrophy on the right) - mild bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: parahippocampal gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), anterior cingulate gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right) and entorhinal area (mild atrophy both left/right) - no appreciable degenerative or atrophic changes observed in the parietal lobe - no evident atrophy or tissue thinning seen in the occipital lobe - mild bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: anterior insula (mild-to-moderate atrophy on the left and mild atrophy on the right), posterior insula (mild atrophy on the left and mild-to-moderate atrophy on the right), frontal operculum (mild atrophy on the left and normal on the right) and parietal operculum (mild atrophy on the left and normal on the right)
AD
ADNI_033_S_5235_MR_MPRAGE_br_raw_20130627094517258_155_S193564_I378404
On a T1-weighted brain MRI we observed: For the ventricles: - no evident size increase noted in the inf. lateral ventricle - mild enlargement of the 4th ventricle - mild enlargement of the external csf - mild-to-moderate enlargement of the 3rd ventricle - mild enlargement of the right lateral ventricle; normal-to-mild enlargement of the left lateral ventricle For the cerebral cortex: - temporal lobe demonstrates a healthy morphology without signs of atrophy - no findings suggestive of atrophy are seen in the occipital lobe - no observable atrophic changes in the frontal lobe - mild atrophy of the left parietal lobe; the right parietal lobe is normal; focal volume loss observed in the following subregions: supramarginal gyrus (mild-to-moderate atrophy on the left) and angular gyrus (mild atrophy on the left and normal on the right) - the insular cortex shows no notable changes suggestive of atrophy - mild atrophy of the right limbic cortex; normal-to-mild atrophy of the left limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right) For the subcortical structures: - caudate demonstrates a healthy morphology without signs of atrophy - hippocampus demonstrates a healthy morphology without signs of atrophy - basal forebrain demonstrates a healthy morphology without signs of atrophy - no findings suggestive of atrophy are seen in the pallidum - mild atrophy of the left accumbens; the right accumbens is normal - thalamus demonstrates a healthy morphology without signs of atrophy - putamen appears within normal limits without apparent atrophy - amygdala appears preserved, with no observable tissue loss - no appreciable degenerative or atrophic changes observed in the ventral dc
CN
ADNI_037_S_10209_MR_Accelerated_Sagittal_MPRAGE_MSV21_br_raw_20241213190901902_1_I11075831
On a T1-weighted brain MRI we observed: For the ventricles: - inf. lateral ventricle maintains a typical volume without observable enlargement - no clear enlargement or abnormal growth seen in the 3rd ventricle - moderate enlargement of the 4th ventricle - external csf maintains a typical volume without observable enlargement - no evident size increase noted in the lateral ventricle For the subcortical structures: - mild bilateral atrophy of the accumbens - hippocampus maintains a normal appearance with no observable atrophic features - pallidum demonstrates a healthy morphology without signs of atrophy - the basal forebrain shows no notable changes suggestive of atrophy - no evident atrophy or tissue thinning seen in the putamen - no clear atrophic alterations are visible in the thalamus - no observable atrophic changes in the caudate - amygdala appears preserved, with no observable tissue loss - no observable atrophic changes in the ventral dc For the cerebral cortex: - insular cortex demonstrates a healthy morphology without signs of atrophy - the parietal lobe shows no notable changes suggestive of atrophy - no appreciable degenerative or atrophic changes observed in the occipital lobe - limbic cortex demonstrates a healthy morphology without signs of atrophy - the frontal lobe shows no notable changes suggestive of atrophy - temporal lobe demonstrates a healthy morphology without signs of atrophy
CN
FTLD_203833156_02653_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178165
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild-to-moderate atrophy of the left hippocampus - the left hippocampus volume is borderline low - pallidum demonstrates a healthy morphology without signs of atrophy - severe atrophy of the left amygdala and moderate-to-severe atrophy of the right amygdala - no clear atrophic alterations are visible in the thalamus - mild-to-moderate atrophy of the left putamen; the right putamen is normal - mild-to-moderate atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens - ventral dc appears preserved, with no observable tissue loss - caudate appears within normal limits without apparent atrophy - no appreciable degenerative or atrophic changes observed in the basal forebrain For the ventricles: - mild enlargement of the external csf - severe enlargement of the left inf. lateral ventricle and mild-to-moderate enlargement of the right inf. lateral ventricle - no appreciable enlargement noted in the 3rd ventricle - the lateral ventricle shows no notable changes suggestive of enlargement - 4th ventricle maintains its expected proportions without signs of enlargement For the cerebral cortex: - occipital lobe demonstrates a healthy morphology without signs of atrophy - no evident atrophy or tissue thinning seen in the parietal lobe - frontal lobe appears preserved, with no observable tissue loss - mild atrophy of the right limbic cortex; normal-to-mild atrophy of the left limbic cortex; focal volume loss observed in the following subregions: entorhinal area (mild-to-moderate atrophy on the left and mild atrophy on the right) and parahippocampal gyrus (mild atrophy both left/right) - severe atrophy of the left temporal lobe and mild-to-moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), middle temporal gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), fusiform gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), planum temporale (normal-to-mild atrophy on the left and mild atrophy on the right), inf. temporal gyrus (mild-to-moderate atrophy on the left and normal on the right) and sup. temporal gyrus (mild-to-moderate atrophy on the left and normal on the right) - mild-to-moderate bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), posterior insula (moderate atrophy on the left and mild-to-moderate atrophy on the right), central operculum (mild atrophy on the right) and parietal operculum (normal on the left and mild atrophy on the right)
SV
ADNI_109_S_6218_MR_Accelerated_Sagittal_MPRAGE__br_raw_20180409104711193_158_S674381_I982856
On a T1-weighted brain MRI we observed: For the subcortical structures: - thalamus appears within normal limits without apparent atrophy - caudate maintains a normal appearance with no observable atrophic features - no observable atrophic changes in the putamen - no clear atrophic alterations are visible in the ventral dc - amygdala demonstrates a healthy morphology without signs of atrophy - no appreciable degenerative or atrophic changes observed in the hippocampus - pallidum appears preserved, with no observable tissue loss - basal forebrain appears within normal limits without apparent atrophy - accumbens appears within normal limits without apparent atrophy For the cerebral cortex: - no observable atrophic changes in the occipital lobe - temporal lobe maintains a normal appearance with no observable atrophic features - mild atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: middle cingulate gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right) - insular cortex appears within normal limits without apparent atrophy - no evident atrophy or tissue thinning seen in the frontal lobe - no clear atrophic alterations are visible in the parietal lobe For the ventricles: - no findings suggestive of enlargement are seen in the external csf - inf. lateral ventricle maintains its expected proportions without signs of enlargement - no appreciable enlargement noted in the 4th ventricle - no clear enlargement or abnormal growth seen in the 3rd ventricle - no evident size increase noted in the lateral ventricle
CN
ADNI_035_S_7001_MR_Accelerated_Sagittal_MPRAGE_Phase_A-P__br_raw_20211028164628878_138_S1077098_I1509946
On a T1-weighted brain MRI we observed: For the subcortical structures: - the ventral dc shows no notable changes suggestive of atrophy - no appreciable degenerative or atrophic changes observed in the basal forebrain - mild atrophy of the left hippocampus - the left hippocampus volume is borderline low - mild atrophy of the left amygdala; the right amygdala is normal - mild atrophy of the left putamen; the right putamen is normal - thalamus appears within normal limits without apparent atrophy - no evident atrophy or tissue thinning seen in the pallidum - mild atrophy of the left accumbens; the right accumbens is normal - no observable atrophic changes in the caudate For the ventricles: - mild enlargement of the 4th ventricle - mild bilateral enlargement of the lateral ventricle - moderate-to-severe enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle - no appreciable enlargement noted in the external csf - 3rd ventricle maintains a typical volume without observable enlargement For the cerebral cortex: - no evident atrophy or tissue thinning seen in the occipital lobe - no evident atrophy or tissue thinning seen in the limbic cortex - mild atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (mild atrophy both left/right) and central operculum (mild atrophy on the left and normal on the right) - no observable atrophic changes in the temporal lobe - parietal lobe demonstrates a healthy morphology without signs of atrophy - no clear atrophic alterations are visible in the frontal lobe
AD
FTLD_203679862_03267_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450433
On a T1-weighted brain MRI we observed: For the cerebral cortex: - temporal lobe appears within normal limits without apparent atrophy - insular cortex appears within normal limits without apparent atrophy - parietal lobe appears within normal limits without apparent atrophy - mild atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (normal on the left and mild atrophy on the right), parahippocampal gyrus (normal on the left and mild atrophy on the right) and anterior cingulate gyrus (normal on the left and mild atrophy on the right) - occipital lobe maintains a normal appearance with no observable atrophic features - frontal lobe appears within normal limits without apparent atrophy For the subcortical structures: - mild-to-moderate atrophy of the right amygdala; the left amygdala is normal - no clear atrophic alterations are visible in the basal forebrain - mild atrophy of the left ventral dc and mild-to-moderate atrophy of the right ventral dc - no clear atrophic alterations are visible in the accumbens - mild-to-moderate bilateral atrophy of the thalamus - caudate demonstrates a healthy morphology without signs of atrophy - mild bilateral atrophy of the pallidum - mild bilateral atrophy of the putamen - mild atrophy of the right hippocampus For the ventricles: - mild bilateral enlargement of the lateral ventricle - mild enlargement of the external csf - no observable enlargement of the 4th ventricle - inf. lateral ventricle maintains its expected proportions without signs of enlargement - no findings suggestive of enlargement are seen in the 3rd ventricle
PNFA
FTLD_203773746_03647_MR_Accelerated_Sagittal_MPRAGE_br_raw_20241_I11047639
On a T1-weighted brain MRI we observed: For the ventricles: - moderate enlargement of the external csf - the lateral ventricle shows no notable changes suggestive of enlargement - inf. lateral ventricle maintains its expected proportions without signs of enlargement - 3rd ventricle appears to be of normal dimensions, with no observable increase in size - no observable enlargement of the 4th ventricle For the cerebral cortex: - mild atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and normal-to-mild atrophy on the right) - mild atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: middle temporal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right) and planum polare (normal on the left and mild atrophy on the right) - no evident atrophy or tissue thinning seen in the parietal lobe - mild-to-moderate bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: gyrus rectus (mild atrophy on the left and normal-to-mild atrophy on the right), middle frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), precentral gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), orbital inf. frontal gyrus (mild atrophy on the left and normal on the right), lateral orbital gyrus (normal on the left and mild atrophy on the right), anterior orbital gyrus (mild atrophy on the left) and sup. frontal gyrus (mild atrophy on the left and normal on the right) - occipital lobe demonstrates a healthy morphology without signs of atrophy - mild atrophy of the right limbic cortex; normal-to-mild atrophy of the left limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and parahippocampal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) For the subcortical structures: - accumbens appears preserved, with no observable tissue loss - hippocampus maintains a normal appearance with no observable atrophic features - mild atrophy of the right pallidum; normal-to-mild atrophy of the left pallidum - mild-to-moderate bilateral atrophy of the caudate - no observable atrophic changes in the putamen - no observable atrophic changes in the thalamus - mild-to-moderate atrophy of the left amygdala and mild atrophy of the right amygdala - no appreciable degenerative or atrophic changes observed in the basal forebrain - ventral dc appears preserved, with no observable tissue loss
PNFA
FTLD_203628476_03672_MR_Accelerated_Sagittal_IR-FSPGR_br_raw_202_I10451045
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild-to-moderate atrophy of the left putamen and mild atrophy of the right putamen - moderate atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens - basal forebrain maintains a normal appearance with no observable atrophic features - mild-to-moderate atrophy of the left thalamus and mild atrophy of the right thalamus - mild-to-moderate atrophy of the left ventral dc and mild atrophy of the right ventral dc - mild atrophy of the right amygdala; normal-to-mild atrophy of the left amygdala - moderate atrophy of the left caudate and mild-to-moderate atrophy of the right caudate - moderate-to-severe atrophy of the left pallidum and mild atrophy of the right pallidum - the left hippocampus volume is borderline low - the left hippocampus volume is borderline low For the ventricles: - mild enlargement of the external csf - mild-to-moderate enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle - no observable enlargement of the 4th ventricle - mild-to-moderate bilateral enlargement of the lateral ventricle - mild-to-moderate enlargement of the 3rd ventricle For the cerebral cortex: - no appreciable degenerative or atrophic changes observed in the occipital lobe - insular cortex maintains a normal appearance with no observable atrophic features - mild atrophy of the left parietal lobe; the right parietal lobe is normal - mild atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: sup. temporal gyrus (mild atrophy on the left), planum temporale (moderate atrophy on the left and normal on the right), transverse temporal gyrus (mild atrophy on the left) and temporal pole (mild atrophy on the left and normal on the right) - limbic cortex appears preserved, with no observable tissue loss - no observable atrophic changes in the frontal lobe
PNFA
ADNI_014_S_4401_MR_MPRAGE_br_raw_20111202113251695_83_S131598_I269615
On a T1-weighted brain MRI we observed: For the subcortical structures: - caudate appears within normal limits without apparent atrophy - the ventral dc shows no notable changes suggestive of atrophy - the pallidum shows no notable changes suggestive of atrophy - no evident atrophy or tissue thinning seen in the amygdala - moderate atrophy of the left basal forebrain and mild atrophy of the right basal forebrain - no observable atrophic changes in the thalamus - no observable atrophic changes in the putamen - hippocampus appears preserved, with no observable tissue loss - the accumbens shows no notable changes suggestive of atrophy For the ventricles: - no evident size increase noted in the lateral ventricle - external csf maintains its expected proportions without signs of enlargement - inf. lateral ventricle appears to be of normal dimensions, with no observable increase in size - 4th ventricle appears within normal size limits with no apparent enlargement - no clear enlargement or abnormal growth seen in the 3rd ventricle For the cerebral cortex: - mild atrophy of the left parietal lobe; normal-to-mild atrophy of the right parietal lobe; focal volume loss observed in the following subregions: postcentral gyrus (normal on the left and mild atrophy on the right) and sup. parietal lobule (mild atrophy on the left and normal on the right) - no clear atrophic alterations are visible in the limbic cortex - no findings suggestive of atrophy are seen in the frontal lobe - no observable atrophic changes in the temporal lobe - insular cortex maintains a normal appearance with no observable atrophic features - no evident atrophy or tissue thinning seen in the occipital lobe
CN
FTLD_203192379_02979_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178310
On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: middle cingulate gyrus (mild atrophy on the right) - no clear atrophic alterations are visible in the temporal lobe - no findings suggestive of atrophy are seen in the insular cortex - no findings suggestive of atrophy are seen in the frontal lobe - parietal lobe appears within normal limits without apparent atrophy - occipital lobe appears preserved, with no observable tissue loss For the subcortical structures: - ventral dc maintains a normal appearance with no observable atrophic features - amygdala appears within normal limits without apparent atrophy - no observable atrophic changes in the pallidum - mild atrophy of the right accumbens; normal-to-mild atrophy of the left accumbens - no observable atrophic changes in the thalamus - the caudate shows no notable changes suggestive of atrophy - basal forebrain maintains a normal appearance with no observable atrophic features - no evident atrophy or tissue thinning seen in the putamen - no clear atrophic alterations are visible in the hippocampus For the ventricles: - no evident size increase noted in the 4th ventricle - 3rd ventricle appears within normal size limits with no apparent enlargement - external csf appears within normal size limits with no apparent enlargement - lateral ventricle appears to be of normal dimensions, with no observable increase in size - inf. lateral ventricle maintains its expected proportions without signs of enlargement
BV
FTLD_203856309_03905_MR_Accelerated_Sagittal_MPRAGE_br_raw_20241_I11047976
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild-to-moderate bilateral atrophy of the pallidum - no observable atrophic changes in the thalamus - severe bilateral atrophy of the putamen - mild-to-moderate atrophy of the left hippocampus - mild-to-moderate atrophy of the right hippocampus - severe atrophy of the left amygdala and moderate-to-severe atrophy of the right amygdala - the ventral dc shows no notable changes suggestive of atrophy - moderate atrophy of the left accumbens and moderate-to-severe atrophy of the right accumbens - severe bilateral atrophy of the caudate - basal forebrain maintains a normal appearance with no observable atrophic features For the cerebral cortex: - mild-to-moderate atrophy of the left limbic cortex and mild atrophy of the right limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy both left/right), posterior cingulate gyrus (mild atrophy on the left and normal on the right) and parahippocampal gyrus (mild atrophy on the left and normal on the right) - moderate-to-severe atrophy of the left temporal lobe and moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate atrophy on the left and mild-to-moderate atrophy on the right), planum temporale (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), fusiform gyrus (mild atrophy both left/right), middle temporal gyrus (mild atrophy both left/right), transverse temporal gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), inf. temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. temporal gyrus (normal on the left and mild atrophy on the right) and planum polare (normal on the left and mild atrophy on the right) - mild-to-moderate bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: sup. frontal gyrus (moderate atrophy on the left and mild atrophy on the right), medial frontal cortex (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), precentral gyrus (mild atrophy both left/right), precentral gyrus medial segment (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), gyrus rectus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. frontal gyrus medial segment (mild atrophy on the left and normal-to-mild atrophy on the right), opercular inf. frontal gyrus (mild atrophy on the left and normal on the right) and supplementary motor cortex (mild atrophy on the left) - occipital lobe appears preserved, with no observable tissue loss - mild bilateral atrophy of the parietal lobe; focal volume loss observed in the following subregions: postcentral gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), precuneus (mild atrophy on the left and normal-to-mild atrophy on the right) and sup. parietal lobule (mild atrophy on the left) - moderate atrophy of the left insular cortex and mild-to-moderate atrophy of the right insular cortex; focal volume loss observed in the following subregions: central operculum (mild-to-moderate atrophy on the left and mild atrophy on the right), parietal operculum (mild atrophy both left/right), posterior insula (normal on the left and mild-to-moderate atrophy on the right) and anterior insula (mild atrophy on the left and normal on the right) For the ventricles: - 4th ventricle maintains a typical volume without observable enlargement - mild enlargement of the 3rd ventricle - severe enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle - severe bilateral enlargement of the lateral ventricle - severe enlargement of the external csf
BV
FTLD_203735377_03773_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10451145
On a T1-weighted brain MRI we observed: For the ventricles: - severe enlargement of the left inf. lateral ventricle and mild-to-moderate enlargement of the right inf. lateral ventricle - no clear enlargement or abnormal growth seen in the 3rd ventricle - 4th ventricle maintains a typical volume without observable enlargement - external csf maintains its expected proportions without signs of enlargement - mild-to-moderate bilateral enlargement of the lateral ventricle For the cerebral cortex: - occipital lobe appears preserved, with no observable tissue loss - no evident atrophy or tissue thinning seen in the parietal lobe - no appreciable degenerative or atrophic changes observed in the insular cortex - no observable atrophic changes in the limbic cortex - severe atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (severe atrophy on the left and mild-to-moderate atrophy on the right), inf. temporal gyrus (moderate-to-severe atrophy on the left), fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and middle temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) - frontal lobe maintains a normal appearance with no observable atrophic features For the subcortical structures: - no appreciable degenerative or atrophic changes observed in the thalamus - no findings suggestive of atrophy are seen in the caudate - pallidum appears within normal limits without apparent atrophy - no evident atrophy or tissue thinning seen in the ventral dc - putamen demonstrates a healthy morphology without signs of atrophy - severe atrophy of the left amygdala and mild-to-moderate atrophy of the right amygdala - basal forebrain maintains a normal appearance with no observable atrophic features - mild-to-moderate atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens - mild-to-moderate atrophy of the left hippocampus - the left hippocampus volume is borderline low
SV
FTLD_203437946_02643_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178155
On a T1-weighted brain MRI we observed: For the ventricles: - inf. lateral ventricle maintains a typical volume without observable enlargement - mild-to-moderate enlargement of the left lateral ventricle and mild enlargement of the right lateral ventricle - no clear enlargement or abnormal growth seen in the 4th ventricle - moderate enlargement of the external csf - mild enlargement of the 3rd ventricle For the subcortical structures: - no clear atrophic alterations are visible in the ventral dc - mild-to-moderate atrophy of the left pallidum and mild atrophy of the right pallidum - basal forebrain appears within normal limits without apparent atrophy - mild-to-moderate atrophy of the left putamen and mild atrophy of the right putamen - mild atrophy of the left thalamus; normal-to-mild atrophy of the right thalamus - no clear atrophic alterations are visible in the hippocampus - mild bilateral atrophy of the amygdala - mild atrophy of the left caudate; normal-to-mild atrophy of the right caudate - no observable atrophic changes in the accumbens For the cerebral cortex: - mild bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: fusiform gyrus (mild-to-moderate atrophy on the left and normal on the right) and temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right) - mild-to-moderate atrophy of the left parietal lobe and mild atrophy of the right parietal lobe; focal volume loss observed in the following subregions: angular gyrus (mild atrophy both left/right) and postcentral gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) - mild-to-moderate atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: central operculum (mild atrophy both left/right) and posterior insula (mild atrophy on the left and normal on the right) - mild atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the right) - no evident atrophy or tissue thinning seen in the occipital lobe - moderate atrophy of the left frontal lobe and mild-to-moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: precentral gyrus (moderate-to-severe atrophy on the left and moderate atrophy on the right), middle frontal gyrus (moderate atrophy on the left and normal on the right), opercular inf. frontal gyrus (mild atrophy both left/right), sup. frontal gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), sup. frontal gyrus medial segment (mild atrophy on the left and normal-to-mild atrophy on the right), precentral gyrus medial segment (mild atrophy on the left) and supplementary motor cortex (normal on the left and mild atrophy on the right)
PNFA
ADNI_019_S_5180_MR_MPRAGE_br_raw_20130522161055863_149_S190310_I373541
On a T1-weighted brain MRI we observed: For the subcortical structures: - the basal forebrain shows no notable changes suggestive of atrophy - no clear atrophic alterations are visible in the accumbens - mild atrophy of the left caudate; normal-to-mild atrophy of the right caudate - the hippocampus shows no notable changes suggestive of atrophy - no clear atrophic alterations are visible in the ventral dc - amygdala appears within normal limits without apparent atrophy - pallidum appears within normal limits without apparent atrophy - no findings suggestive of atrophy are seen in the putamen - no observable atrophic changes in the thalamus For the ventricles: - external csf maintains a typical volume without observable enlargement - mild bilateral enlargement of the lateral ventricle - mild enlargement of the 3rd ventricle - no findings suggestive of enlargement are seen in the 4th ventricle - mild-to-moderate enlargement of the left inf. lateral ventricle; normal-to-mild enlargement of the right inf. lateral ventricle For the cerebral cortex: - insular cortex appears within normal limits without apparent atrophy - no appreciable degenerative or atrophic changes observed in the temporal lobe - occipital lobe appears preserved, with no observable tissue loss - mild atrophy of the right parietal lobe; normal-to-mild atrophy of the left parietal lobe; focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), supramarginal gyrus (normal on the left and mild atrophy on the right) and precuneus (normal on the left and mild atrophy on the right) - limbic cortex appears within normal limits without apparent atrophy - frontal lobe maintains a normal appearance with no observable atrophic features
CN
ADNI_027_S_5288_MR_Accelerated_Sag_IR-FSPGR_br_raw_20130918141640842_23_S201426_I390934
On a T1-weighted brain MRI we observed: For the ventricles: - no appreciable enlargement noted in the lateral ventricle - mild bilateral enlargement of the inf. lateral ventricle - mild enlargement of the 4th ventricle - external csf maintains a typical volume without observable enlargement - no observable enlargement of the 3rd ventricle For the cerebral cortex: - no evident atrophy or tissue thinning seen in the insular cortex - mild atrophy of the right occipital lobe; normal-to-mild atrophy of the left occipital lobe; focal volume loss observed in the following subregions: sup. occipital gyrus (normal on the left and moderate atrophy on the right), calcarine cortex (mild atrophy both left/right), lingual gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and inf. occipital gyrus (mild atrophy on the left) - parietal lobe demonstrates a healthy morphology without signs of atrophy - frontal lobe appears preserved, with no observable tissue loss - temporal lobe demonstrates a healthy morphology without signs of atrophy - no observable atrophic changes in the limbic cortex For the subcortical structures: - pallidum appears preserved, with no observable tissue loss - ventral dc demonstrates a healthy morphology without signs of atrophy - no evident atrophy or tissue thinning seen in the caudate - putamen demonstrates a healthy morphology without signs of atrophy - accumbens maintains a normal appearance with no observable atrophic features - no observable atrophic changes in the amygdala - no evident atrophy or tissue thinning seen in the basal forebrain - hippocampus maintains a normal appearance with no observable atrophic features - no clear atrophic alterations are visible in the thalamus
CN
FTLD_203590286_02689_MR_Accelerated_Sagittal_IR-FSPGR_br_raw_202_I10176953
On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild atrophy of the right temporal lobe; normal-to-mild atrophy of the left temporal lobe; focal volume loss observed in the following subregions: temporal pole (mild atrophy both left/right) and sup. temporal gyrus (mild atrophy on the left and normal on the right) - limbic cortex demonstrates a healthy morphology without signs of atrophy - occipital lobe demonstrates a healthy morphology without signs of atrophy - no clear atrophic alterations are visible in the insular cortex - frontal lobe demonstrates a healthy morphology without signs of atrophy - no findings suggestive of atrophy are seen in the parietal lobe For the subcortical structures: - no clear atrophic alterations are visible in the pallidum - basal forebrain appears preserved, with no observable tissue loss - no appreciable degenerative or atrophic changes observed in the hippocampus - amygdala appears preserved, with no observable tissue loss - putamen demonstrates a healthy morphology without signs of atrophy - thalamus demonstrates a healthy morphology without signs of atrophy - mild bilateral atrophy of the caudate - ventral dc appears preserved, with no observable tissue loss - mild atrophy of the left accumbens; the right accumbens is normal For the ventricles: - no evident size increase noted in the 4th ventricle - inf. lateral ventricle maintains its expected proportions without signs of enlargement - external csf maintains a typical volume without observable enlargement - lateral ventricle appears within normal size limits with no apparent enlargement - no observable enlargement of the 3rd ventricle
PNFA
FTLD_203355715_01515_MR_Sagittal_MP-Rage_br_raw_20230206143046077_I10181202
On a T1-weighted brain MRI we observed: For the cerebral cortex: - temporal lobe demonstrates a healthy morphology without signs of atrophy - no evident atrophy or tissue thinning seen in the occipital lobe - limbic cortex appears preserved, with no observable tissue loss - mild bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: precentral gyrus (mild atrophy both left/right), sup. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), sup. frontal gyrus medial segment (normal-to-mild atrophy on the left and mild atrophy on the right), triangular inf. frontal gyrus (mild atrophy on the left and normal on the right), gyrus rectus (mild atrophy on the left and normal on the right) and medial orbital gyrus (normal on the left and mild atrophy on the right) - no appreciable degenerative or atrophic changes observed in the insular cortex - no clear atrophic alterations are visible in the parietal lobe For the ventricles: - mild enlargement of the external csf - the 4th ventricle shows no notable changes suggestive of enlargement - moderate bilateral enlargement of the lateral ventricle - mild enlargement of the 3rd ventricle - mild enlargement of the left inf. lateral ventricle; normal-to-mild enlargement of the right inf. lateral ventricle For the subcortical structures: - ventral dc maintains a normal appearance with no observable atrophic features - no observable atrophic changes in the amygdala - the left hippocampus volume is borderline low - no evident atrophy or tissue thinning seen in the basal forebrain - mild atrophy of the left putamen; normal-to-mild atrophy of the right putamen - no clear atrophic alterations are visible in the accumbens - mild-to-moderate atrophy of the left thalamus and mild atrophy of the right thalamus - mild bilateral atrophy of the caudate - no clear atrophic alterations are visible in the pallidum
PNFA
FTLD_203773746_03647_MR_Accelerated_Sagittal_MPRAGE_br_raw_20241_I11047639
On a T1-weighted brain MRI we observed: For the subcortical structures: - hippocampus demonstrates a healthy morphology without signs of atrophy - thalamus maintains a normal appearance with no observable atrophic features - mild-to-moderate bilateral atrophy of the caudate - no findings suggestive of atrophy are seen in the ventral dc - no clear atrophic alterations are visible in the putamen - mild-to-moderate atrophy of the left amygdala and mild atrophy of the right amygdala - mild atrophy of the right pallidum; normal-to-mild atrophy of the left pallidum - no appreciable degenerative or atrophic changes observed in the basal forebrain - accumbens appears preserved, with no observable tissue loss For the cerebral cortex: - occipital lobe appears preserved, with no observable tissue loss - parietal lobe maintains a normal appearance with no observable atrophic features - mild-to-moderate bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: gyrus rectus (mild atrophy on the left and normal-to-mild atrophy on the right), middle frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), precentral gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), orbital inf. frontal gyrus (mild atrophy on the left and normal on the right), lateral orbital gyrus (normal on the left and mild atrophy on the right), anterior orbital gyrus (mild atrophy on the left) and sup. frontal gyrus (mild atrophy on the left and normal on the right) - mild atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: middle temporal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right) and planum polare (normal on the left and mild atrophy on the right) - mild atrophy of the right limbic cortex; normal-to-mild atrophy of the left limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and parahippocampal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) - mild atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and normal-to-mild atrophy on the right) For the ventricles: - no evident size increase noted in the 3rd ventricle - no evident size increase noted in the inf. lateral ventricle - moderate enlargement of the external csf - no evident size increase noted in the 4th ventricle - no findings suggestive of enlargement are seen in the lateral ventricle
PNFA
FTLD_203149534_01434_MR_Sagittal_MP-Rage_br_raw_20230206142016642_I10181173
On a T1-weighted brain MRI we observed: For the ventricles: - moderate-to-severe enlargement of the left lateral ventricle and mild-to-moderate enlargement of the right lateral ventricle - mild-to-moderate enlargement of the 3rd ventricle - no observable enlargement of the 4th ventricle - external csf appears within normal size limits with no apparent enlargement - severe enlargement of the left inf. lateral ventricle and moderate enlargement of the right inf. lateral ventricle For the cerebral cortex: - temporal lobe appears within normal limits without apparent atrophy - mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: posterior cingulate gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) - mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: central operculum (mild-to-moderate atrophy on the left and normal on the right) and parietal operculum (mild atrophy on the left and normal on the right) - parietal lobe demonstrates a healthy morphology without signs of atrophy - mild-to-moderate bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: precentral gyrus (mild atrophy both left/right), anterior orbital gyrus (mild atrophy both left/right), precentral gyrus medial segment (mild atrophy both left/right), opercular inf. frontal gyrus (mild-to-moderate atrophy on the left and normal on the right), lateral orbital gyrus (mild atrophy on the left), middle frontal gyrus (mild atrophy on the left and normal on the right), posterior orbital gyrus (mild atrophy on the left and normal on the right), sup. frontal gyrus medial segment (normal on the left and mild atrophy on the right), gyrus rectus (mild atrophy on the left) and medial frontal cortex (mild atrophy on the left) - no evident atrophy or tissue thinning seen in the occipital lobe For the subcortical structures: - no evident atrophy or tissue thinning seen in the basal forebrain - mild atrophy of the left putamen; normal-to-mild atrophy of the right putamen - no clear atrophic alterations are visible in the amygdala - no evident atrophy or tissue thinning seen in the pallidum - no appreciable degenerative or atrophic changes observed in the ventral dc - mild bilateral atrophy of the accumbens - thalamus appears preserved, with no observable tissue loss - mild bilateral atrophy of the caudate - no observable atrophic changes in the hippocampus
PNFA
FTLD_203735377_03773_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10451145
On a T1-weighted brain MRI we observed: For the cerebral cortex: - the frontal lobe shows no notable changes suggestive of atrophy - no observable atrophic changes in the insular cortex - no evident atrophy or tissue thinning seen in the occipital lobe - severe atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (severe atrophy on the left and mild-to-moderate atrophy on the right), inf. temporal gyrus (moderate-to-severe atrophy on the left), fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and middle temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) - no findings suggestive of atrophy are seen in the parietal lobe - limbic cortex maintains a normal appearance with no observable atrophic features For the ventricles: - mild-to-moderate bilateral enlargement of the lateral ventricle - external csf appears within normal size limits with no apparent enlargement - no clear enlargement or abnormal growth seen in the 4th ventricle - 3rd ventricle maintains its expected proportions without signs of enlargement - severe enlargement of the left inf. lateral ventricle and mild-to-moderate enlargement of the right inf. lateral ventricle For the subcortical structures: - mild-to-moderate atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens - ventral dc demonstrates a healthy morphology without signs of atrophy - severe atrophy of the left amygdala and mild-to-moderate atrophy of the right amygdala - no appreciable degenerative or atrophic changes observed in the caudate - mild-to-moderate atrophy of the left hippocampus - the left hippocampus volume is borderline low - no observable atrophic changes in the putamen - thalamus appears within normal limits without apparent atrophy - no evident atrophy or tissue thinning seen in the basal forebrain - no observable atrophic changes in the pallidum
SV
ADNI_023_S_4796_MR_MPRAGE_GRAPPA2_br_raw_20130322153627924_142_S185076_I364199
On a T1-weighted brain MRI we observed: For the cerebral cortex: - parietal lobe appears within normal limits without apparent atrophy - mild atrophy of the left occipital lobe; the right occipital lobe is normal; focal volume loss observed in the following subregions: inf. occipital gyrus (mild atrophy both left/right) - mild atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: posterior insula (normal-to-mild atrophy on the left and moderate atrophy on the right) and central operculum (mild atrophy both left/right) - mild bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: inf. temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), planum polare (mild atrophy on the left and normal on the right) and middle temporal gyrus (normal on the left and mild atrophy on the right) - mild atrophy of the left limbic cortex; normal-to-mild atrophy of the right limbic cortex; focal volume loss observed in the following subregions: parahippocampal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and anterior cingulate gyrus (mild atrophy on the left) - the frontal lobe shows no notable changes suggestive of atrophy For the subcortical structures: - basal forebrain appears preserved, with no observable tissue loss - thalamus maintains a normal appearance with no observable atrophic features - the left hippocampus volume is borderline low - the left hippocampus volume is borderline low - no evident atrophy or tissue thinning seen in the pallidum - mild atrophy of the left amygdala and mild-to-moderate atrophy of the right amygdala - no clear atrophic alterations are visible in the putamen - caudate appears preserved, with no observable tissue loss - ventral dc maintains a normal appearance with no observable atrophic features - the accumbens shows no notable changes suggestive of atrophy For the ventricles: - moderate-to-severe enlargement of the left inf. lateral ventricle and mild-to-moderate enlargement of the right inf. lateral ventricle - no evident size increase noted in the external csf - mild enlargement of the 3rd ventricle - no appreciable enlargement noted in the 4th ventricle - no observable enlargement of the lateral ventricle
AD
ADNI_033_S_1285_MR_MPR__GradWarp__B1_Correction__N3__Scaled_Br_20070426175923899_S26128_I51588
On a T1-weighted brain MRI we observed: For the subcortical structures: - no evident atrophy or tissue thinning seen in the putamen - ventral dc appears within normal limits without apparent atrophy - no clear atrophic alterations are visible in the caudate - accumbens appears preserved, with no observable tissue loss - no clear atrophic alterations are visible in the pallidum - mild atrophy of the left hippocampus - mild atrophy of the right hippocampus - no appreciable degenerative or atrophic changes observed in the basal forebrain - the thalamus shows no notable changes suggestive of atrophy - mild atrophy of the left amygdala; normal-to-mild atrophy of the right amygdala For the ventricles: - no evident size increase noted in the inf. lateral ventricle - no evident size increase noted in the 4th ventricle - lateral ventricle appears within normal size limits with no apparent enlargement - the external csf shows no notable changes suggestive of enlargement - no evident size increase noted in the 3rd ventricle For the cerebral cortex: - no findings suggestive of atrophy are seen in the limbic cortex - the temporal lobe shows no notable changes suggestive of atrophy - no evident atrophy or tissue thinning seen in the parietal lobe - occipital lobe appears preserved, with no observable tissue loss - no findings suggestive of atrophy are seen in the insular cortex - no evident atrophy or tissue thinning seen in the frontal lobe
AD
FTLD_203197205_03509_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450866
On a T1-weighted brain MRI we observed: For the cerebral cortex: - parietal lobe demonstrates a healthy morphology without signs of atrophy - occipital lobe demonstrates a healthy morphology without signs of atrophy - mild-to-moderate atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: parahippocampal gyrus (moderate atrophy on the left and normal on the right), entorhinal area (mild-to-moderate atrophy on the left and normal on the right), middle cingulate gyrus (mild atrophy on the left) and posterior cingulate gyrus (mild atrophy on the left and normal on the right) - severe atrophy of the left temporal lobe and moderate-to-severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (mild-to-moderate atrophy both left/right), inf. temporal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), middle temporal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), fusiform gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), planum polare (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) and sup. temporal gyrus (mild atrophy on the left) - the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in medial frontal cortex (moderate atrophy on the left), gyrus rectus (mild atrophy on the left and normal-to-mild atrophy on the right), precentral gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and sup. frontal gyrus medial segment (normal on the left and mild atrophy on the right) - moderate atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and mild atrophy on the right), posterior insula (mild-to-moderate atrophy on the left and mild atrophy on the right) and parietal operculum (normal-to-mild atrophy on the left and mild atrophy on the right) For the ventricles: - 3rd ventricle maintains its expected proportions without signs of enlargement - external csf maintains a typical volume without observable enlargement - no appreciable enlargement noted in the 4th ventricle - mild-to-moderate enlargement of the left lateral ventricle and mild enlargement of the right lateral ventricle - moderate-to-severe enlargement of the left inf. lateral ventricle; normal-to-mild enlargement of the right inf. lateral ventricle For the subcortical structures: - severe atrophy of the left amygdala and moderate-to-severe atrophy of the right amygdala - moderate atrophy of the left hippocampus - mild atrophy of the right hippocampus - the ventral dc shows no notable changes suggestive of atrophy - mild atrophy of the left basal forebrain; the right basal forebrain is normal - mild atrophy of the left pallidum; the right pallidum is normal - caudate appears preserved, with no observable tissue loss - no appreciable degenerative or atrophic changes observed in the thalamus - mild atrophy of the left accumbens; the right accumbens is normal - mild-to-moderate atrophy of the left putamen and mild atrophy of the right putamen
SV
FTLD_203545403_03304_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10176941
On a T1-weighted brain MRI we observed: For the ventricles: - mild enlargement of the external csf - mild enlargement of the 3rd ventricle - 4th ventricle maintains a typical volume without observable enlargement - severe bilateral enlargement of the lateral ventricle - severe bilateral enlargement of the inf. lateral ventricle For the subcortical structures: - moderate-to-severe atrophy of the left amygdala and severe atrophy of the right amygdala - moderate-to-severe atrophy of the left hippocampus - severe atrophy of the right hippocampus - the basal forebrain shows no notable changes suggestive of atrophy - severe bilateral atrophy of the putamen - moderate atrophy of the left pallidum and severe atrophy of the right pallidum - severe bilateral atrophy of the accumbens - severe bilateral atrophy of the caudate - mild-to-moderate atrophy of the right thalamus; normal-to-mild atrophy of the left thalamus - mild atrophy of the right ventral dc; normal-to-mild atrophy of the left ventral dc For the cerebral cortex: - no findings suggestive of atrophy are seen in the occipital lobe - moderate atrophy of the right frontal lobe; normal-to-mild atrophy of the left frontal lobe; focal volume loss observed in the following subregions: sup. frontal gyrus medial segment (mild atrophy on the left and mild-to-moderate atrophy on the right), medial frontal cortex (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), medial orbital gyrus (mild atrophy both left/right), gyrus rectus (mild atrophy both left/right), triangular inf. frontal gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), opercular inf. frontal gyrus (normal on the left and mild-to-moderate atrophy on the right), posterior orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. frontal gyrus (normal on the left and mild atrophy on the right) and lateral orbital gyrus (mild atrophy on the left and normal on the right) - moderate bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: entorhinal area (mild-to-moderate atrophy on the left and moderate atrophy on the right), anterior cingulate gyrus (mild-to-moderate atrophy both left/right) and parahippocampal gyrus (mild-to-moderate atrophy both left/right) - mild-to-moderate atrophy of the right temporal lobe; the left temporal lobe is normal; focal volume loss observed in the following subregions: temporal pole (mild atrophy on the left and moderate atrophy on the right) and inf. temporal gyrus (normal on the left and mild atrophy on the right) - no clear atrophic alterations are visible in the parietal lobe - mild-to-moderate atrophy of the left insular cortex and moderate atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and severe atrophy on the right), posterior insula (mild-to-moderate atrophy both left/right) and frontal operculum (normal-to-mild atrophy on the left and mild atrophy on the right)
BV
FTLD_203460005_01506_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177588
On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild atrophy of the right frontal lobe; normal-to-mild atrophy of the left frontal lobe; focal volume loss observed in the following subregions: sup. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), precentral gyrus (normal on the left and mild atrophy on the right), supplementary motor cortex (mild atrophy on the left and normal on the right) and frontal pole (normal on the left and mild atrophy on the right) - no evident atrophy or tissue thinning seen in the insular cortex - no evident atrophy or tissue thinning seen in the limbic cortex - no appreciable degenerative or atrophic changes observed in the parietal lobe - no observable atrophic changes in the temporal lobe - occipital lobe appears preserved, with no observable tissue loss For the subcortical structures: - amygdala appears within normal limits without apparent atrophy - no appreciable degenerative or atrophic changes observed in the caudate - no observable atrophic changes in the accumbens - no findings suggestive of atrophy are seen in the thalamus - putamen appears within normal limits without apparent atrophy - no appreciable degenerative or atrophic changes observed in the ventral dc - the left hippocampus volume is borderline low - pallidum appears preserved, with no observable tissue loss - the basal forebrain shows no notable changes suggestive of atrophy For the ventricles: - no observable enlargement of the 3rd ventricle - no findings suggestive of enlargement are seen in the 4th ventricle - no clear enlargement or abnormal growth seen in the external csf - the lateral ventricle shows no notable changes suggestive of enlargement - mild enlargement of the right inf. lateral ventricle; normal-to-mild enlargement of the left inf. lateral ventricle
CN
ADNI_068_S_0442_MR_MPR____N3__Scaled_Br_20070911105840316_S34034_I72437
On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild atrophy of the left limbic cortex; normal-to-mild atrophy of the right limbic cortex; focal volume loss observed in the following subregions: parahippocampal gyrus (mild-to-moderate atrophy both left/right), entorhinal area (normal on the left and mild atrophy on the right) and anterior cingulate gyrus (mild atrophy on the left and normal on the right) - mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) and frontal operculum (mild atrophy on the left) - no clear atrophic alterations are visible in the occipital lobe - frontal lobe appears preserved, with no observable tissue loss - no evident atrophy or tissue thinning seen in the parietal lobe - moderate atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: temporal pole (moderate atrophy on the left and mild atrophy on the right), fusiform gyrus (mild atrophy on the left and normal on the right) and middle temporal gyrus (mild atrophy on the left and normal on the right) For the subcortical structures: - moderate atrophy of the left amygdala and mild-to-moderate atrophy of the right amygdala - severe atrophy of the left hippocampus - mild-to-moderate atrophy of the right hippocampus - mild bilateral atrophy of the accumbens - putamen appears preserved, with no observable tissue loss - basal forebrain demonstrates a healthy morphology without signs of atrophy - mild atrophy of the left thalamus; normal-to-mild atrophy of the right thalamus - mild bilateral atrophy of the ventral dc - no observable atrophic changes in the caudate - no evident atrophy or tissue thinning seen in the pallidum For the ventricles: - mild enlargement of the 3rd ventricle - mild enlargement of the external csf - no appreciable enlargement noted in the 4th ventricle - lateral ventricle appears to be of normal dimensions, with no observable increase in size - mild-to-moderate enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle
AD
FTLD_203236666_01663_MR_Sagittal_MP-Rage_br_raw_20230206173923274_I10182172
On a T1-weighted brain MRI we observed: For the cerebral cortex: - moderate atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: sup. temporal gyrus (moderate atrophy on the left and normal on the right), inf. temporal gyrus (mild atrophy on the left and normal on the right) and middle temporal gyrus (mild atrophy on the left and normal on the right) - parietal lobe appears within normal limits without apparent atrophy - moderate-to-severe atrophy of the left frontal lobe and mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), opercular inf. frontal gyrus (moderate atrophy on the left and mild atrophy on the right), sup. frontal gyrus medial segment (mild atrophy both left/right), medial orbital gyrus (mild atrophy on the left and normal on the right), sup. frontal gyrus (mild atrophy on the left and normal on the right) and lateral orbital gyrus (mild atrophy on the left) - limbic cortex appears within normal limits without apparent atrophy - occipital lobe appears within normal limits without apparent atrophy - mild-to-moderate atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and mild atrophy on the right), frontal operculum (mild atrophy both left/right) and parietal operculum (mild atrophy on the left) For the subcortical structures: - mild atrophy of the left thalamus; the right thalamus is normal - the basal forebrain shows no notable changes suggestive of atrophy - no findings suggestive of atrophy are seen in the ventral dc - mild atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens - mild bilateral atrophy of the amygdala - mild-to-moderate atrophy of the left caudate and mild atrophy of the right caudate - mild-to-moderate atrophy of the left putamen and mild atrophy of the right putamen - the left hippocampus volume is borderline low - no findings suggestive of atrophy are seen in the pallidum For the ventricles: - mild enlargement of the right lateral ventricle; normal-to-mild enlargement of the left lateral ventricle - moderate enlargement of the external csf - no clear enlargement or abnormal growth seen in the 3rd ventricle - mild-to-moderate enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle - no evident size increase noted in the 4th ventricle
BV
ADNI_021_S_0424_MR_MPR__GradWarp__N3__Scaled_Br_20101111161351528_S84608_I204863
On a T1-weighted brain MRI we observed: For the ventricles: - the external csf shows no notable changes suggestive of enlargement - 3rd ventricle appears to be of normal dimensions, with no observable increase in size - 4th ventricle maintains its expected proportions without signs of enlargement - mild bilateral enlargement of the lateral ventricle - mild bilateral enlargement of the inf. lateral ventricle For the subcortical structures: - no observable atrophic changes in the ventral dc - basal forebrain maintains a normal appearance with no observable atrophic features - putamen maintains a normal appearance with no observable atrophic features - amygdala maintains a normal appearance with no observable atrophic features - accumbens demonstrates a healthy morphology without signs of atrophy - no clear atrophic alterations are visible in the hippocampus - no appreciable degenerative or atrophic changes observed in the thalamus - pallidum appears within normal limits without apparent atrophy - no clear atrophic alterations are visible in the caudate For the cerebral cortex: - the frontal lobe shows no notable changes suggestive of atrophy - limbic cortex demonstrates a healthy morphology without signs of atrophy - mild-to-moderate atrophy of the left parietal lobe; normal-to-mild atrophy of the right parietal lobe; focal volume loss observed in the following subregions: sup. parietal lobule (mild atrophy on the left and normal-to-mild atrophy on the right), postcentral gyrus (normal on the left and mild atrophy on the right) and supramarginal gyrus (mild atrophy on the left) - insular cortex maintains a normal appearance with no observable atrophic features - occipital lobe appears preserved, with no observable tissue loss - no clear atrophic alterations are visible in the temporal lobe
AD
FTLD_203875531_03137_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450288
On a T1-weighted brain MRI we observed: For the cerebral cortex: - the insular cortex shows no notable changes suggestive of atrophy - no findings suggestive of atrophy are seen in the frontal lobe - no evident atrophy or tissue thinning seen in the parietal lobe - moderate atrophy of the left temporal lobe; normal-to-mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy on the left), fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), planum polare (mild atrophy on the left and normal on the right) and middle temporal gyrus (mild atrophy on the left and normal on the right) - the occipital lobe shows no notable changes suggestive of atrophy - no clear atrophic alterations are visible in the limbic cortex For the ventricles: - no appreciable enlargement noted in the 4th ventricle - no appreciable enlargement noted in the 3rd ventricle - external csf maintains a typical volume without observable enlargement - lateral ventricle maintains a typical volume without observable enlargement - severe enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal For the subcortical structures: - severe atrophy of the left amygdala; the right amygdala is normal - thalamus appears within normal limits without apparent atrophy - the left hippocampus volume is borderline low - no evident atrophy or tissue thinning seen in the accumbens - mild-to-moderate atrophy of the left pallidum; normal-to-mild atrophy of the right pallidum - no evident atrophy or tissue thinning seen in the basal forebrain - no findings suggestive of atrophy are seen in the caudate - ventral dc appears within normal limits without apparent atrophy - no clear atrophic alterations are visible in the putamen
SV
FTLD_203355715_01515_MR_Sagittal_MP-Rage_br_raw_20230206143046077_I10181202
On a T1-weighted brain MRI we observed: For the ventricles: - mild enlargement of the external csf - no findings suggestive of enlargement are seen in the 4th ventricle - mild enlargement of the 3rd ventricle - moderate bilateral enlargement of the lateral ventricle - mild enlargement of the left inf. lateral ventricle; normal-to-mild enlargement of the right inf. lateral ventricle For the cerebral cortex: - mild bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: precentral gyrus (mild atrophy both left/right), sup. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), sup. frontal gyrus medial segment (normal-to-mild atrophy on the left and mild atrophy on the right), triangular inf. frontal gyrus (mild atrophy on the left and normal on the right), gyrus rectus (mild atrophy on the left and normal on the right) and medial orbital gyrus (normal on the left and mild atrophy on the right) - limbic cortex appears within normal limits without apparent atrophy - insular cortex appears within normal limits without apparent atrophy - the parietal lobe shows no notable changes suggestive of atrophy - the occipital lobe shows no notable changes suggestive of atrophy - no appreciable degenerative or atrophic changes observed in the temporal lobe For the subcortical structures: - no clear atrophic alterations are visible in the basal forebrain - no evident atrophy or tissue thinning seen in the pallidum - mild-to-moderate atrophy of the left thalamus and mild atrophy of the right thalamus - accumbens demonstrates a healthy morphology without signs of atrophy - amygdala appears within normal limits without apparent atrophy - no findings suggestive of atrophy are seen in the ventral dc - mild atrophy of the left putamen; normal-to-mild atrophy of the right putamen - the left hippocampus volume is borderline low - mild bilateral atrophy of the caudate
PNFA
FTLD_203044563_03364_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10450611
On a T1-weighted brain MRI we observed: For the ventricles: - 3rd ventricle maintains its expected proportions without signs of enlargement - mild-to-moderate enlargement of the external csf - no observable enlargement of the 4th ventricle - mild bilateral enlargement of the lateral ventricle - mild-to-moderate enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal For the cerebral cortex: - moderate atrophy of the left limbic cortex; normal-to-mild atrophy of the right limbic cortex; focal volume loss observed in the following subregions: entorhinal area (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), parahippocampal gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), posterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and anterior cingulate gyrus (mild atrophy on the left) - mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and normal-to-mild atrophy on the right) and posterior insula (mild atrophy both left/right) - no findings suggestive of atrophy are seen in the parietal lobe - frontal lobe demonstrates a healthy morphology without signs of atrophy - severe atrophy of the left temporal lobe; normal-to-mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: fusiform gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), temporal pole (moderate-to-severe atrophy on the left and mild atrophy on the right), inf. temporal gyrus (moderate-to-severe atrophy on the left and normal-to-mild atrophy on the right) and middle temporal gyrus (mild atrophy on the left) - mild atrophy of the left occipital lobe; normal-to-mild atrophy of the right occipital lobe; focal volume loss observed in the following subregions: calcarine cortex (mild atrophy both left/right), middle occipital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), lingual gyrus (mild atrophy on the left and normal on the right), occipital fusiform gyrus (normal on the left and mild atrophy on the right) and inf. occipital gyrus (mild atrophy on the left) For the subcortical structures: - mild atrophy of the left accumbens; the right accumbens is normal - moderate-to-severe atrophy of the left hippocampus - mild atrophy of the right hippocampus - severe atrophy of the left amygdala and moderate-to-severe atrophy of the right amygdala - no evident atrophy or tissue thinning seen in the ventral dc - no clear atrophic alterations are visible in the thalamus - putamen appears preserved, with no observable tissue loss - mild atrophy of the left caudate; the right caudate is normal - basal forebrain appears preserved, with no observable tissue loss - no appreciable degenerative or atrophic changes observed in the pallidum
SV
ADNI_036_S_4714_MR_MT1__GradWarp__N3m_Br_20160809114938278_S446882_I764966
On a T1-weighted brain MRI we observed: For the ventricles: - external csf maintains its expected proportions without signs of enlargement - no findings suggestive of enlargement are seen in the 3rd ventricle - lateral ventricle appears within normal size limits with no apparent enlargement - no observable enlargement of the 4th ventricle - no clear enlargement or abnormal growth seen in the inf. lateral ventricle For the subcortical structures: - pallidum maintains a normal appearance with no observable atrophic features - mild atrophy of the left basal forebrain; normal-to-mild atrophy of the right basal forebrain - thalamus appears preserved, with no observable tissue loss - no findings suggestive of atrophy are seen in the hippocampus - ventral dc appears within normal limits without apparent atrophy - accumbens appears within normal limits without apparent atrophy - mild-to-moderate bilateral atrophy of the amygdala - no findings suggestive of atrophy are seen in the putamen - the caudate shows no notable changes suggestive of atrophy For the cerebral cortex: - the insular cortex shows no notable changes suggestive of atrophy - temporal lobe maintains a normal appearance with no observable atrophic features - mild-to-moderate atrophy of the left frontal lobe and mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), lateral orbital gyrus (mild atrophy both left/right), frontal pole (mild atrophy both left/right), supplementary motor cortex (mild atrophy both left/right) and anterior orbital gyrus (normal on the left and mild atrophy on the right) - the occipital lobe shows no notable changes suggestive of atrophy - limbic cortex appears within normal limits without apparent atrophy - parietal lobe appears preserved, with no observable tissue loss
AD
FTLD_203098865_03569_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450937
On a T1-weighted brain MRI we observed: For the subcortical structures: - moderate-to-severe atrophy of the left hippocampus - severe atrophy of the right hippocampus - moderate atrophy of the left pallidum and mild-to-moderate atrophy of the right pallidum - mild bilateral atrophy of the ventral dc - moderate-to-severe bilateral atrophy of the putamen - severe atrophy of the left caudate and moderate atrophy of the right caudate - moderate atrophy of the left amygdala and severe atrophy of the right amygdala - no appreciable degenerative or atrophic changes observed in the basal forebrain - severe atrophy of the left accumbens and moderate-to-severe atrophy of the right accumbens - mild-to-moderate bilateral atrophy of the thalamus For the cerebral cortex: - temporal lobe maintains a normal appearance with no observable atrophic features - no observable atrophic changes in the parietal lobe - mild-to-moderate bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: posterior orbital gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), sup. frontal gyrus medial segment (mild atrophy both left/right), gyrus rectus (mild atrophy both left/right), medial orbital gyrus (mild atrophy both left/right), frontal pole (normal-to-mild atrophy on the left and mild atrophy on the right), orbital inf. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), triangular inf. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), middle frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and anterior orbital gyrus (mild atrophy on the left and normal on the right) - mild-to-moderate atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy both left/right) and entorhinal area (mild atrophy on the right) - occipital lobe appears preserved, with no observable tissue loss - mild atrophy of the right insular cortex; the left insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (mild atrophy both left/right), frontal operculum (mild atrophy both left/right) and posterior insula (normal-to-mild atrophy on the left and mild atrophy on the right) For the ventricles: - 4th ventricle appears within normal size limits with no apparent enlargement - severe bilateral enlargement of the lateral ventricle - severe bilateral enlargement of the inf. lateral ventricle - mild enlargement of the external csf - moderate enlargement of the 3rd ventricle
BV
FTLD_203177063_03367_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10450616
On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild-to-moderate atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (severe atrophy on the left and moderate atrophy on the right) and frontal operculum (mild-to-moderate atrophy on the left and mild atrophy on the right) - mild-to-moderate atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: sup. frontal gyrus (mild atrophy on the left), opercular inf. frontal gyrus (mild-to-moderate atrophy on the left and normal on the right), posterior orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. frontal gyrus medial segment (mild atrophy on the left and normal-to-mild atrophy on the right), frontal pole (mild atrophy on the left and normal on the right), medial frontal cortex (mild atrophy on the left and normal on the right), medial orbital gyrus (mild atrophy on the left and normal on the right) and gyrus rectus (mild atrophy on the right) - no findings suggestive of atrophy are seen in the limbic cortex - parietal lobe appears preserved, with no observable tissue loss - mild bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: inf. temporal gyrus (mild atrophy both left/right) - no findings suggestive of atrophy are seen in the occipital lobe For the ventricles: - 3rd ventricle maintains a typical volume without observable enlargement - no appreciable enlargement noted in the 4th ventricle - mild enlargement of the external csf - lateral ventricle maintains its expected proportions without signs of enlargement - no observable enlargement of the inf. lateral ventricle For the subcortical structures: - hippocampus demonstrates a healthy morphology without signs of atrophy - pallidum maintains a normal appearance with no observable atrophic features - no evident atrophy or tissue thinning seen in the ventral dc - no clear atrophic alterations are visible in the thalamus - mild atrophy of the left putamen; the right putamen is normal - basal forebrain appears preserved, with no observable tissue loss - mild atrophy of the left caudate; the right caudate is normal - mild bilateral atrophy of the amygdala - mild bilateral atrophy of the accumbens
PNFA
ADNI_035_S_7001_MR_Accelerated_Sagittal_MPRAGE_Phase_A-P__br_raw_20211028164628878_138_S1077098_I1509946
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild atrophy of the left accumbens; the right accumbens is normal - mild atrophy of the left hippocampus - the left hippocampus volume is borderline low - ventral dc appears within normal limits without apparent atrophy - mild atrophy of the left amygdala; the right amygdala is normal - no findings suggestive of atrophy are seen in the basal forebrain - no evident atrophy or tissue thinning seen in the thalamus - the pallidum shows no notable changes suggestive of atrophy - mild atrophy of the left putamen; the right putamen is normal - no findings suggestive of atrophy are seen in the caudate For the ventricles: - 3rd ventricle maintains a typical volume without observable enlargement - moderate-to-severe enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle - mild enlargement of the 4th ventricle - the external csf shows no notable changes suggestive of enlargement - mild bilateral enlargement of the lateral ventricle For the cerebral cortex: - mild atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (mild atrophy both left/right) and central operculum (mild atrophy on the left and normal on the right) - limbic cortex maintains a normal appearance with no observable atrophic features - temporal lobe appears within normal limits without apparent atrophy - no appreciable degenerative or atrophic changes observed in the frontal lobe - occipital lobe maintains a normal appearance with no observable atrophic features - no observable atrophic changes in the parietal lobe
AD
ADNI_009_S_5037_MR_MPRAGE_GRAPPA2_br_raw_20130115124943538_34_S180196_I355084
On a T1-weighted brain MRI we observed: For the subcortical structures: - moderate atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens - moderate-to-severe atrophy of the left putamen and moderate atrophy of the right putamen - moderate-to-severe bilateral atrophy of the pallidum - moderate atrophy of the left thalamus and mild-to-moderate atrophy of the right thalamus - moderate bilateral atrophy of the caudate - severe atrophy of the left amygdala and moderate-to-severe atrophy of the right amygdala - mild atrophy of the left ventral dc and mild-to-moderate atrophy of the right ventral dc - no observable atrophic changes in the basal forebrain - moderate atrophy of the left hippocampus - moderate atrophy of the right hippocampus For the cerebral cortex: - mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and normal on the right) - occipital lobe demonstrates a healthy morphology without signs of atrophy - mild-to-moderate atrophy of the left limbic cortex; normal-to-mild atrophy of the right limbic cortex; focal volume loss observed in the following subregions: parahippocampal gyrus (moderate atrophy on the left and mild atrophy on the right), entorhinal area (mild atrophy on the left and normal-to-mild atrophy on the right), anterior cingulate gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and middle cingulate gyrus (mild atrophy on the left) - mild atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: inf. temporal gyrus (mild-to-moderate atrophy on the left and normal on the right) and middle temporal gyrus (mild atrophy on the left and normal on the right) - the parietal lobe shows no notable changes suggestive of atrophy - the frontal lobe shows no notable changes suggestive of atrophy For the ventricles: - severe enlargement of the left inf. lateral ventricle and mild-to-moderate enlargement of the right inf. lateral ventricle - no findings suggestive of enlargement are seen in the 4th ventricle - moderate-to-severe enlargement of the left lateral ventricle and severe enlargement of the right lateral ventricle - mild-to-moderate enlargement of the external csf - mild enlargement of the 3rd ventricle
AD
ADNI_014_S_6522_MR_Accelerated_Sagittal_MPRAGE__br_raw_20180820130203983_41_S718494_I1037958
On a T1-weighted brain MRI we observed: For the ventricles: - lateral ventricle maintains a typical volume without observable enlargement - mild enlargement of the external csf - inf. lateral ventricle appears to be of normal dimensions, with no observable increase in size - 3rd ventricle maintains a typical volume without observable enlargement - no findings suggestive of enlargement are seen in the 4th ventricle For the subcortical structures: - mild atrophy of the left putamen; normal-to-mild atrophy of the right putamen - accumbens appears preserved, with no observable tissue loss - mild atrophy of the left basal forebrain; the right basal forebrain is normal - mild atrophy of the left thalamus; normal-to-mild atrophy of the right thalamus - hippocampus appears preserved, with no observable tissue loss - mild bilateral atrophy of the pallidum - no clear atrophic alterations are visible in the amygdala - no clear atrophic alterations are visible in the caudate - mild bilateral atrophy of the ventral dc For the cerebral cortex: - limbic cortex demonstrates a healthy morphology without signs of atrophy - temporal lobe appears within normal limits without apparent atrophy - no findings suggestive of atrophy are seen in the parietal lobe - mild atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: precentral gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), gyrus rectus (normal on the left and mild atrophy on the right) and sup. frontal gyrus medial segment (mild atrophy on the left and normal on the right) - no appreciable degenerative or atrophic changes observed in the occipital lobe - insular cortex appears within normal limits without apparent atrophy
CN
FTLD_203884749_02948_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177893
On a T1-weighted brain MRI we observed: For the ventricles: - no observable enlargement of the 4th ventricle - moderate-to-severe enlargement of the 3rd ventricle - moderate-to-severe enlargement of the external csf - mild enlargement of the left lateral ventricle and mild-to-moderate enlargement of the right lateral ventricle - severe bilateral enlargement of the inf. lateral ventricle For the subcortical structures: - mild atrophy of the right pallidum; the left pallidum is normal - moderate atrophy of the left caudate and severe atrophy of the right caudate - the ventral dc shows no notable changes suggestive of atrophy - thalamus appears preserved, with no observable tissue loss - moderate atrophy of the left putamen and severe atrophy of the right putamen - severe bilateral atrophy of the amygdala - mild-to-moderate atrophy of the left hippocampus - severe atrophy of the right hippocampus - severe bilateral atrophy of the accumbens - no findings suggestive of atrophy are seen in the basal forebrain For the cerebral cortex: - mild-to-moderate atrophy of the left temporal lobe and moderate-to-severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy both left/right), middle temporal gyrus (normal-to-mild atrophy on the left and moderate-to-severe atrophy on the right), fusiform gyrus (mild atrophy both left/right), inf. temporal gyrus (normal on the left and mild atrophy on the right) and planum polare (mild atrophy on the right) - mild-to-moderate atrophy of the left insular cortex and moderate atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (severe atrophy both left/right), posterior insula (mild-to-moderate atrophy both left/right), frontal operculum (mild atrophy both left/right) and central operculum (mild atrophy on the left and normal on the right) - no clear atrophic alterations are visible in the parietal lobe - moderate-to-severe atrophy of the left frontal lobe and severe atrophy of the right frontal lobe; focal volume loss observed in the following subregions: gyrus rectus (mild-to-moderate atrophy on the left and moderate-to-severe atrophy on the right), medial orbital gyrus (moderate atrophy both left/right), frontal pole (mild atrophy on the left and moderate-to-severe atrophy on the right), sup. frontal gyrus medial segment (mild-to-moderate atrophy both left/right), middle frontal gyrus (mild atrophy on the left and moderate atrophy on the right), sup. frontal gyrus (mild atrophy on the left and moderate atrophy on the right), medial frontal cortex (normal-to-mild atrophy on the left and moderate atrophy on the right), posterior orbital gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), subcallosal area (mild-to-moderate atrophy on the left and mild atrophy on the right), lateral orbital gyrus (mild atrophy both left/right), anterior orbital gyrus (normal on the left and mild-to-moderate atrophy on the right), opercular inf. frontal gyrus (normal on the left and mild atrophy on the right) and supplementary motor cortex (mild atrophy on the left and normal on the right) - moderate atrophy of the left limbic cortex and severe atrophy of the right limbic cortex; focal volume loss observed in the following subregions: entorhinal area (moderate atrophy on the left and severe atrophy on the right), anterior cingulate gyrus (moderate atrophy on the left and moderate-to-severe atrophy on the right), middle cingulate gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and parahippocampal gyrus (normal on the left and mild-to-moderate atrophy on the right) - occipital lobe appears preserved, with no observable tissue loss
BV
FTLD_203885673_02378_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177207
On a T1-weighted brain MRI we observed: For the cerebral cortex: - parietal lobe appears preserved, with no observable tissue loss - severe atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy on the left and moderate atrophy on the right), planum polare (mild atrophy both left/right), middle temporal gyrus (mild-to-moderate atrophy on the left and normal on the right), fusiform gyrus (mild-to-moderate atrophy on the left) and inf. temporal gyrus (mild atrophy on the left and normal on the right) - no evident atrophy or tissue thinning seen in the occipital lobe - mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and mild atrophy on the right) and posterior insula (mild atrophy on the left and normal-to-mild atrophy on the right) - mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (moderate atrophy on the left and mild atrophy on the right) and parahippocampal gyrus (mild atrophy both left/right) - no evident atrophy or tissue thinning seen in the frontal lobe For the subcortical structures: - ventral dc demonstrates a healthy morphology without signs of atrophy - no appreciable degenerative or atrophic changes observed in the basal forebrain - mild-to-moderate atrophy of the left accumbens and mild atrophy of the right accumbens - severe atrophy of the left amygdala and moderate atrophy of the right amygdala - thalamus maintains a normal appearance with no observable atrophic features - mild atrophy of the left pallidum; normal-to-mild atrophy of the right pallidum - mild-to-moderate atrophy of the left putamen; the right putamen is normal - moderate atrophy of the left hippocampus - the left hippocampus volume is borderline low - caudate appears preserved, with no observable tissue loss For the ventricles: - external csf maintains its expected proportions without signs of enlargement - mild-to-moderate enlargement of the left lateral ventricle; the right lateral ventricle is normal - 3rd ventricle appears within normal size limits with no apparent enlargement - no evident size increase noted in the 4th ventricle - severe enlargement of the left inf. lateral ventricle and mild-to-moderate enlargement of the right inf. lateral ventricle
SV
FTLD_203160043_01346_MR_Sagittal_MP-Rage_br_raw_20230206140338189_I10181124
On a T1-weighted brain MRI we observed: For the cerebral cortex: - the limbic cortex shows no notable changes suggestive of atrophy - no findings suggestive of atrophy are seen in the occipital lobe - mild atrophy of the right frontal lobe; the left frontal lobe is normal; focal volume loss observed in the following subregions: precentral gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), sup. frontal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right) and precentral gyrus medial segment (mild-to-moderate atrophy on the left) - no evident atrophy or tissue thinning seen in the parietal lobe - no evident atrophy or tissue thinning seen in the insular cortex - no observable atrophic changes in the temporal lobe For the subcortical structures: - accumbens appears within normal limits without apparent atrophy - the basal forebrain shows no notable changes suggestive of atrophy - no observable atrophic changes in the ventral dc - putamen appears preserved, with no observable tissue loss - no observable atrophic changes in the pallidum - the left hippocampus volume is borderline low - the left hippocampus volume is borderline low - amygdala appears within normal limits without apparent atrophy - mild atrophy of the right caudate; the left caudate is normal - thalamus maintains a normal appearance with no observable atrophic features For the ventricles: - mild bilateral enlargement of the inf. lateral ventricle - 4th ventricle appears to be of normal dimensions, with no observable increase in size - no clear enlargement or abnormal growth seen in the external csf - mild-to-moderate enlargement of the 3rd ventricle - mild enlargement of the left lateral ventricle and moderate enlargement of the right lateral ventricle
PNFA
FTLD_203280208_03808_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10451159
On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild atrophy of the left limbic cortex and mild-to-moderate atrophy of the right limbic cortex; focal volume loss observed in the following subregions: parahippocampal gyrus (moderate atrophy on the left and mild atrophy on the right), entorhinal area (mild atrophy both left/right) and anterior cingulate gyrus (normal on the left and mild atrophy on the right) - parietal lobe maintains a normal appearance with no observable atrophic features - mild-to-moderate bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: anterior insula (mild-to-moderate atrophy both left/right) and parietal operculum (normal on the left and mild atrophy on the right) - occipital lobe appears preserved, with no observable tissue loss - the frontal lobe shows no notable changes suggestive of atrophy - severe atrophy of the left temporal lobe and moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate atrophy both left/right), inf. temporal gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), fusiform gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), planum temporale (normal-to-mild atrophy on the left and mild atrophy on the right) and middle temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) For the ventricles: - mild enlargement of the left inf. lateral ventricle; normal-to-mild enlargement of the right inf. lateral ventricle - mild enlargement of the external csf - no findings suggestive of enlargement are seen in the lateral ventricle - 4th ventricle maintains a typical volume without observable enlargement - 3rd ventricle appears within normal size limits with no apparent enlargement For the subcortical structures: - thalamus appears within normal limits without apparent atrophy - ventral dc appears within normal limits without apparent atrophy - no appreciable degenerative or atrophic changes observed in the caudate - severe atrophy of the left amygdala and moderate-to-severe atrophy of the right amygdala - pallidum appears within normal limits without apparent atrophy - no findings suggestive of atrophy are seen in the putamen - no appreciable degenerative or atrophic changes observed in the basal forebrain - mild atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens - mild-to-moderate atrophy of the left hippocampus - mild-to-moderate atrophy of the right hippocampus
SV
FTLD_203979630_03037_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10176924
On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild-to-moderate bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: entorhinal area (mild-to-moderate atrophy both left/right), parahippocampal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right) and posterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) - frontal lobe appears within normal limits without apparent atrophy - mild bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: posterior insula (mild-to-moderate atrophy on the left and moderate-to-severe atrophy on the right) and anterior insula (mild atrophy on the left and mild-to-moderate atrophy on the right) - no appreciable degenerative or atrophic changes observed in the occipital lobe - parietal lobe maintains a normal appearance with no observable atrophic features - mild-to-moderate atrophy of the left temporal lobe and moderate-to-severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (mild-to-moderate atrophy on the left and moderate atrophy on the right), inf. temporal gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), sup. temporal gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), planum temporale (normal-to-mild atrophy on the left and mild atrophy on the right), transverse temporal gyrus (mild atrophy on the left), fusiform gyrus (normal on the left and mild atrophy on the right) and middle temporal gyrus (normal on the left and mild atrophy on the right) For the ventricles: - mild-to-moderate enlargement of the 3rd ventricle - 4th ventricle maintains a typical volume without observable enlargement - the external csf shows no notable changes suggestive of enlargement - mild-to-moderate bilateral enlargement of the lateral ventricle - severe bilateral enlargement of the inf. lateral ventricle For the subcortical structures: - mild bilateral atrophy of the caudate - no observable atrophic changes in the thalamus - mild atrophy of the left pallidum and mild-to-moderate atrophy of the right pallidum - no evident atrophy or tissue thinning seen in the ventral dc - moderate atrophy of the left putamen and moderate-to-severe atrophy of the right putamen - no clear atrophic alterations are visible in the basal forebrain - moderate atrophy of the left accumbens and moderate-to-severe atrophy of the right accumbens - moderate-to-severe atrophy of the left hippocampus - severe atrophy of the right hippocampus - severe bilateral atrophy of the amygdala
BV
FTLD_203913818_02811_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10176891
On a T1-weighted brain MRI we observed: For the ventricles: - mild-to-moderate bilateral enlargement of the lateral ventricle - no evident size increase noted in the inf. lateral ventricle - 3rd ventricle maintains a typical volume without observable enlargement - external csf appears to be of normal dimensions, with no observable increase in size - no findings suggestive of enlargement are seen in the 4th ventricle For the subcortical structures: - mild atrophy of the left caudate; the right caudate is normal - mild bilateral atrophy of the putamen - basal forebrain appears within normal limits without apparent atrophy - no clear atrophic alterations are visible in the ventral dc - mild bilateral atrophy of the accumbens - moderate-to-severe atrophy of the left pallidum and moderate atrophy of the right pallidum - moderate atrophy of the left thalamus and mild atrophy of the right thalamus - no evident atrophy or tissue thinning seen in the amygdala - mild-to-moderate atrophy of the left hippocampus For the cerebral cortex: - no clear atrophic alterations are visible in the limbic cortex - no evident atrophy or tissue thinning seen in the insular cortex - frontal lobe appears preserved, with no observable tissue loss - occipital lobe maintains a normal appearance with no observable atrophic features - parietal lobe appears preserved, with no observable tissue loss - temporal lobe demonstrates a healthy morphology without signs of atrophy
BV
FTLD_203735377_03773_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10451145
On a T1-weighted brain MRI we observed: For the ventricles: - 4th ventricle maintains a typical volume without observable enlargement - the 3rd ventricle shows no notable changes suggestive of enlargement - no evident size increase noted in the external csf - mild-to-moderate bilateral enlargement of the lateral ventricle - severe enlargement of the left inf. lateral ventricle and mild-to-moderate enlargement of the right inf. lateral ventricle For the subcortical structures: - caudate appears preserved, with no observable tissue loss - the ventral dc shows no notable changes suggestive of atrophy - putamen maintains a normal appearance with no observable atrophic features - mild-to-moderate atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens - severe atrophy of the left amygdala and mild-to-moderate atrophy of the right amygdala - no appreciable degenerative or atrophic changes observed in the thalamus - mild-to-moderate atrophy of the left hippocampus - the left hippocampus volume is borderline low - no appreciable degenerative or atrophic changes observed in the basal forebrain - pallidum appears preserved, with no observable tissue loss For the cerebral cortex: - the limbic cortex shows no notable changes suggestive of atrophy - no appreciable degenerative or atrophic changes observed in the parietal lobe - occipital lobe demonstrates a healthy morphology without signs of atrophy - no clear atrophic alterations are visible in the frontal lobe - insular cortex appears preserved, with no observable tissue loss - severe atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (severe atrophy on the left and mild-to-moderate atrophy on the right), inf. temporal gyrus (moderate-to-severe atrophy on the left), fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and middle temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right)
SV
FTLD_203317150_03051_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10177392
On a T1-weighted brain MRI we observed: For the subcortical structures: - amygdala appears within normal limits without apparent atrophy - mild atrophy of the right accumbens; normal-to-mild atrophy of the left accumbens - mild atrophy of the left pallidum; the right pallidum is normal - mild atrophy of the left thalamus; normal-to-mild atrophy of the right thalamus - the basal forebrain shows no notable changes suggestive of atrophy - mild atrophy of the left caudate; normal-to-mild atrophy of the right caudate - no observable atrophic changes in the ventral dc - mild-to-moderate atrophy of the left putamen and mild atrophy of the right putamen - mild atrophy of the left hippocampus For the cerebral cortex: - parietal lobe demonstrates a healthy morphology without signs of atrophy - moderate-to-severe atrophy of the left frontal lobe and mild-to-moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), orbital inf. frontal gyrus (mild atrophy both left/right), triangular inf. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), medial frontal cortex (mild atrophy on the left and normal-to-mild atrophy on the right), precentral gyrus (mild-to-moderate atrophy on the left and normal on the right), sup. frontal gyrus (mild-to-moderate atrophy on the left and normal on the right) and supplementary motor cortex (normal on the left and mild atrophy on the right) - limbic cortex appears preserved, with no observable tissue loss - mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: frontal operculum (mild atrophy both left/right) - occipital lobe appears within normal limits without apparent atrophy - temporal lobe maintains a normal appearance with no observable atrophic features For the ventricles: - mild enlargement of the external csf - inf. lateral ventricle appears within normal size limits with no apparent enlargement - 4th ventricle maintains its expected proportions without signs of enlargement - mild enlargement of the left lateral ventricle and mild-to-moderate enlargement of the right lateral ventricle - mild enlargement of the 3rd ventricle
PNFA
FTLD_203154389_01985_MR_Sagittal_MP-Rage_br_raw_20230209094208557_I10183246
On a T1-weighted brain MRI we observed: For the ventricles: - no appreciable enlargement noted in the 4th ventricle - severe bilateral enlargement of the inf. lateral ventricle - moderate-to-severe enlargement of the external csf - moderate-to-severe bilateral enlargement of the lateral ventricle - mild-to-moderate enlargement of the 3rd ventricle For the subcortical structures: - the basal forebrain shows no notable changes suggestive of atrophy - mild-to-moderate bilateral atrophy of the amygdala - moderate bilateral atrophy of the thalamus - the caudate shows no notable changes suggestive of atrophy - mild bilateral atrophy of the pallidum - ventral dc maintains a normal appearance with no observable atrophic features - mild atrophy of the left hippocampus - the left hippocampus volume is borderline low - moderate-to-severe bilateral atrophy of the accumbens - mild-to-moderate bilateral atrophy of the putamen For the cerebral cortex: - occipital lobe appears within normal limits without apparent atrophy - mild atrophy of the left limbic cortex; normal-to-mild atrophy of the right limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) and middle cingulate gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) - mild bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: medial frontal cortex (mild-to-moderate atrophy on the left and mild atrophy on the right), anterior orbital gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), lateral orbital gyrus (moderate atrophy on the left and normal on the right) and sup. frontal gyrus medial segment (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right) - mild-to-moderate atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy on the left and mild atrophy on the right), planum polare (mild atrophy on the left and normal-to-mild atrophy on the right) and inf. temporal gyrus (mild atrophy on the left and normal on the right) - mild atrophy of the right parietal lobe; normal-to-mild atrophy of the left parietal lobe; focal volume loss observed in the following subregions: precuneus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right) and angular gyrus (normal on the left and mild atrophy on the right) - mild-to-moderate bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: central operculum (mild-to-moderate atrophy on the left and mild atrophy on the right), anterior insula (mild atrophy both left/right), posterior insula (mild atrophy both left/right) and parietal operculum (mild atrophy on the right)
BV
ADNI_133_S_0638_MR_MPR__GradWarp__B1_Correction__N3__Scaled_Br_20071028122213506_S39021_I79053
On a T1-weighted brain MRI we observed: For the subcortical structures: - no clear atrophic alterations are visible in the caudate - no appreciable degenerative or atrophic changes observed in the basal forebrain - mild-to-moderate atrophy of the left hippocampus - mild-to-moderate atrophy of the right hippocampus - no observable atrophic changes in the ventral dc - no evident atrophy or tissue thinning seen in the thalamus - no findings suggestive of atrophy are seen in the pallidum - mild bilateral atrophy of the accumbens - putamen appears preserved, with no observable tissue loss - moderate atrophy of the left amygdala and mild-to-moderate atrophy of the right amygdala For the cerebral cortex: - mild atrophy of the right occipital lobe; the left occipital lobe is normal; focal volume loss observed in the following subregions: lingual gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right) - moderate bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: fusiform gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), inf. temporal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), middle temporal gyrus (mild atrophy both left/right), sup. temporal gyrus (mild-to-moderate atrophy on the right) and planum temporale (mild atrophy on the left and normal on the right) - mild atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: parietal operculum (mild atrophy on the left and normal on the right) - frontal lobe appears preserved, with no observable tissue loss - no clear atrophic alterations are visible in the parietal lobe - mild atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (mild-to-moderate atrophy on the right) and middle cingulate gyrus (mild atrophy on the right) For the ventricles: - the external csf shows no notable changes suggestive of enlargement - mild-to-moderate enlargement of the 4th ventricle - lateral ventricle maintains its expected proportions without signs of enlargement - moderate-to-severe enlargement of the left inf. lateral ventricle and severe enlargement of the right inf. lateral ventricle - mild enlargement of the 3rd ventricle
AD
FTLD_203976333_03337_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10177418
On a T1-weighted brain MRI we observed: For the cerebral cortex: - parietal lobe demonstrates a healthy morphology without signs of atrophy - no observable atrophic changes in the occipital lobe - the temporal lobe shows no notable changes suggestive of atrophy - no observable atrophic changes in the limbic cortex - no clear atrophic alterations are visible in the insular cortex - frontal lobe maintains a normal appearance with no observable atrophic features For the ventricles: - no clear enlargement or abnormal growth seen in the inf. lateral ventricle - 3rd ventricle appears to be of normal dimensions, with no observable increase in size - no appreciable enlargement noted in the external csf - no clear enlargement or abnormal growth seen in the 4th ventricle - the lateral ventricle shows no notable changes suggestive of enlargement For the subcortical structures: - ventral dc appears within normal limits without apparent atrophy - accumbens maintains a normal appearance with no observable atrophic features - no findings suggestive of atrophy are seen in the hippocampus - no observable atrophic changes in the basal forebrain - no appreciable degenerative or atrophic changes observed in the putamen - no observable atrophic changes in the caudate - no observable atrophic changes in the thalamus - pallidum appears within normal limits without apparent atrophy - the amygdala shows no notable changes suggestive of atrophy
CN
FTLD_203236666_01663_MR_Sagittal_MP-Rage_br_raw_20230206173923274_I10182172
On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild-to-moderate atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and mild atrophy on the right), frontal operculum (mild atrophy both left/right) and parietal operculum (mild atrophy on the left) - no clear atrophic alterations are visible in the occipital lobe - moderate-to-severe atrophy of the left frontal lobe and mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), opercular inf. frontal gyrus (moderate atrophy on the left and mild atrophy on the right), sup. frontal gyrus medial segment (mild atrophy both left/right), medial orbital gyrus (mild atrophy on the left and normal on the right), sup. frontal gyrus (mild atrophy on the left and normal on the right) and lateral orbital gyrus (mild atrophy on the left) - moderate atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: sup. temporal gyrus (moderate atrophy on the left and normal on the right), inf. temporal gyrus (mild atrophy on the left and normal on the right) and middle temporal gyrus (mild atrophy on the left and normal on the right) - no findings suggestive of atrophy are seen in the parietal lobe - the limbic cortex shows no notable changes suggestive of atrophy For the subcortical structures: - the left hippocampus volume is borderline low - mild atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens - mild bilateral atrophy of the amygdala - mild-to-moderate atrophy of the left putamen and mild atrophy of the right putamen - mild atrophy of the left thalamus; the right thalamus is normal - mild-to-moderate atrophy of the left caudate and mild atrophy of the right caudate - the ventral dc shows no notable changes suggestive of atrophy - no appreciable degenerative or atrophic changes observed in the basal forebrain - no evident atrophy or tissue thinning seen in the pallidum For the ventricles: - no clear enlargement or abnormal growth seen in the 3rd ventricle - mild-to-moderate enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle - 4th ventricle appears within normal size limits with no apparent enlargement - mild enlargement of the right lateral ventricle; normal-to-mild enlargement of the left lateral ventricle - moderate enlargement of the external csf
BV
FTLD_203628476_03672_MR_Accelerated_Sagittal_IR-FSPGR_br_raw_202_I10451045
On a T1-weighted brain MRI we observed: For the subcortical structures: - moderate atrophy of the left caudate and mild-to-moderate atrophy of the right caudate - mild-to-moderate atrophy of the left thalamus and mild atrophy of the right thalamus - mild-to-moderate atrophy of the left putamen and mild atrophy of the right putamen - mild-to-moderate atrophy of the left ventral dc and mild atrophy of the right ventral dc - mild atrophy of the right amygdala; normal-to-mild atrophy of the left amygdala - the left hippocampus volume is borderline low - the left hippocampus volume is borderline low - moderate-to-severe atrophy of the left pallidum and mild atrophy of the right pallidum - moderate atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens - basal forebrain appears within normal limits without apparent atrophy For the ventricles: - mild-to-moderate enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle - mild-to-moderate enlargement of the 3rd ventricle - mild enlargement of the external csf - mild-to-moderate bilateral enlargement of the lateral ventricle - no evident size increase noted in the 4th ventricle For the cerebral cortex: - mild atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: sup. temporal gyrus (mild atrophy on the left), planum temporale (moderate atrophy on the left and normal on the right), transverse temporal gyrus (mild atrophy on the left) and temporal pole (mild atrophy on the left and normal on the right) - occipital lobe appears within normal limits without apparent atrophy - mild atrophy of the left parietal lobe; the right parietal lobe is normal - no findings suggestive of atrophy are seen in the frontal lobe - insular cortex maintains a normal appearance with no observable atrophic features - the limbic cortex shows no notable changes suggestive of atrophy
PNFA
ADNI_168_S_6828_MR_Accelerated_Sagittal_MPRAGE__br_raw_20191014171828541_47_S883939_I1240482
On a T1-weighted brain MRI we observed: For the ventricles: - 3rd ventricle appears within normal size limits with no apparent enlargement - 4th ventricle maintains its expected proportions without signs of enlargement - the lateral ventricle shows no notable changes suggestive of enlargement - no clear enlargement or abnormal growth seen in the external csf - mild-to-moderate bilateral enlargement of the inf. lateral ventricle For the cerebral cortex: - no findings suggestive of atrophy are seen in the limbic cortex - temporal lobe appears within normal limits without apparent atrophy - no evident atrophy or tissue thinning seen in the insular cortex - no observable atrophic changes in the occipital lobe - frontal lobe appears within normal limits without apparent atrophy - parietal lobe maintains a normal appearance with no observable atrophic features For the subcortical structures: - no clear atrophic alterations are visible in the ventral dc - mild atrophy of the left hippocampus - mild-to-moderate atrophy of the right hippocampus - putamen demonstrates a healthy morphology without signs of atrophy - no findings suggestive of atrophy are seen in the caudate - amygdala maintains a normal appearance with no observable atrophic features - thalamus appears within normal limits without apparent atrophy - basal forebrain appears preserved, with no observable tissue loss - no appreciable degenerative or atrophic changes observed in the accumbens - pallidum maintains a normal appearance with no observable atrophic features
AD
FTLD_203057267_02765_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177814
On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: transverse temporal gyrus (mild-to-moderate atrophy on the right), sup. temporal gyrus (mild atrophy both left/right), inf. temporal gyrus (mild-to-moderate atrophy on the left and normal on the right), fusiform gyrus (mild atrophy on the left and normal on the right) and temporal pole (mild atrophy on the left and normal on the right) - no clear atrophic alterations are visible in the occipital lobe - limbic cortex maintains a normal appearance with no observable atrophic features - frontal lobe appears preserved, with no observable tissue loss - mild-to-moderate atrophy of the right insular cortex; normal-to-mild atrophy of the left insular cortex; focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and mild-to-moderate atrophy on the right), posterior insula (mild atrophy both left/right), central operculum (normal-to-mild atrophy on the left and mild atrophy on the right) and parietal operculum (mild atrophy on the right) - parietal lobe maintains a normal appearance with no observable atrophic features For the subcortical structures: - mild atrophy of the left hippocampus - mild atrophy of the right hippocampus - mild-to-moderate atrophy of the left accumbens and mild atrophy of the right accumbens - basal forebrain demonstrates a healthy morphology without signs of atrophy - thalamus appears preserved, with no observable tissue loss - ventral dc demonstrates a healthy morphology without signs of atrophy - mild atrophy of the left amygdala and mild-to-moderate atrophy of the right amygdala - mild bilateral atrophy of the caudate - mild-to-moderate bilateral atrophy of the putamen - mild bilateral atrophy of the pallidum For the ventricles: - moderate enlargement of the left lateral ventricle and moderate-to-severe enlargement of the right lateral ventricle - external csf maintains its expected proportions without signs of enlargement - moderate-to-severe enlargement of the 3rd ventricle - moderate-to-severe bilateral enlargement of the inf. lateral ventricle - mild enlargement of the 4th ventricle
BV
ADNI_133_S_1170_MR_MPR__GradWarp__B1_Correction__N3__Scaled_Br_20080207174424754_S24674_I89957
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild atrophy of the left amygdala and mild-to-moderate atrophy of the right amygdala - mild bilateral atrophy of the thalamus - mild bilateral atrophy of the ventral dc - putamen maintains a normal appearance with no observable atrophic features - mild-to-moderate atrophy of the left hippocampus - mild-to-moderate atrophy of the right hippocampus - mild-to-moderate atrophy of the left pallidum and mild atrophy of the right pallidum - basal forebrain appears within normal limits without apparent atrophy - mild-to-moderate bilateral atrophy of the accumbens - mild-to-moderate bilateral atrophy of the caudate For the cerebral cortex: - no clear atrophic alterations are visible in the frontal lobe - mild atrophy of the right temporal lobe; normal-to-mild atrophy of the left temporal lobe; focal volume loss observed in the following subregions: inf. temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and sup. temporal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) - no appreciable degenerative or atrophic changes observed in the limbic cortex - mild bilateral atrophy of the parietal lobe; focal volume loss observed in the following subregions: sup. parietal lobule (mild atrophy on the left and normal-to-mild atrophy on the right) and postcentral gyrus (mild atrophy on the left and normal on the right) - insular cortex appears preserved, with no observable tissue loss - occipital lobe maintains a normal appearance with no observable atrophic features For the ventricles: - mild enlargement of the right inf. lateral ventricle; the left inf. lateral ventricle is normal - mild-to-moderate enlargement of the external csf - mild enlargement of the 3rd ventricle - 4th ventricle maintains a typical volume without observable enlargement - no findings suggestive of enlargement are seen in the lateral ventricle
AD
ADNI_007_S_4488_MR_Accelerated_SAG_IR-SPGR__br_raw_20120131104026380_93_S138944_I281559
On a T1-weighted brain MRI we observed: For the subcortical structures: - no evident atrophy or tissue thinning seen in the ventral dc - no appreciable degenerative or atrophic changes observed in the caudate - no observable atrophic changes in the hippocampus - basal forebrain demonstrates a healthy morphology without signs of atrophy - no evident atrophy or tissue thinning seen in the amygdala - no clear atrophic alterations are visible in the putamen - thalamus maintains a normal appearance with no observable atrophic features - accumbens appears within normal limits without apparent atrophy - no findings suggestive of atrophy are seen in the pallidum For the cerebral cortex: - no observable atrophic changes in the occipital lobe - no evident atrophy or tissue thinning seen in the limbic cortex - the parietal lobe shows no notable changes suggestive of atrophy - no clear atrophic alterations are visible in the insular cortex - temporal lobe appears preserved, with no observable tissue loss - no findings suggestive of atrophy are seen in the frontal lobe For the ventricles: - no appreciable enlargement noted in the lateral ventricle - no observable enlargement of the 3rd ventricle - external csf maintains a typical volume without observable enlargement - no findings suggestive of enlargement are seen in the inf. lateral ventricle - no findings suggestive of enlargement are seen in the 4th ventricle
CN
FTLD_203788719_01918_MR_Sagittal_MP-Rage_br_raw_20230206152255569_I10181377
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild atrophy of the left putamen; normal-to-mild atrophy of the right putamen - basal forebrain maintains a normal appearance with no observable atrophic features - pallidum appears within normal limits without apparent atrophy - no evident atrophy or tissue thinning seen in the amygdala - hippocampus demonstrates a healthy morphology without signs of atrophy - no clear atrophic alterations are visible in the ventral dc - accumbens demonstrates a healthy morphology without signs of atrophy - thalamus appears within normal limits without apparent atrophy - no evident atrophy or tissue thinning seen in the caudate For the ventricles: - no evident size increase noted in the external csf - lateral ventricle appears within normal size limits with no apparent enlargement - 3rd ventricle maintains its expected proportions without signs of enlargement - no clear enlargement or abnormal growth seen in the inf. lateral ventricle - no observable enlargement of the 4th ventricle For the cerebral cortex: - moderate-to-severe atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: central operculum (moderate atrophy on the left and mild atrophy on the right), anterior insula (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) and parietal operculum (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) - mild atrophy of the left frontal lobe; normal-to-mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: precentral gyrus (moderate atrophy on the left and normal-to-mild atrophy on the right), sup. frontal gyrus medial segment (mild atrophy on the left and normal-to-mild atrophy on the right) and anterior orbital gyrus (mild atrophy on the right) - the parietal lobe shows no notable changes suggestive of atrophy - no findings suggestive of atrophy are seen in the occipital lobe - no observable atrophic changes in the limbic cortex - no clear atrophic alterations are visible in the temporal lobe
PNFA
ADNI_013_S_1186_MR_MPRAGE_ND__br_raw_20150414145636530_77_S252185_I478691
On a T1-weighted brain MRI we observed: For the ventricles: - no appreciable enlargement noted in the 4th ventricle - external csf maintains its expected proportions without signs of enlargement - no appreciable enlargement noted in the lateral ventricle - the 3rd ventricle shows no notable changes suggestive of enlargement - no observable enlargement of the inf. lateral ventricle For the subcortical structures: - no observable atrophic changes in the hippocampus - thalamus maintains a normal appearance with no observable atrophic features - no appreciable degenerative or atrophic changes observed in the accumbens - ventral dc appears within normal limits without apparent atrophy - mild atrophy of the right basal forebrain; the left basal forebrain is normal - mild atrophy of the left amygdala and mild-to-moderate atrophy of the right amygdala - caudate appears preserved, with no observable tissue loss - the pallidum shows no notable changes suggestive of atrophy - putamen maintains a normal appearance with no observable atrophic features For the cerebral cortex: - occipital lobe appears preserved, with no observable tissue loss - mild atrophy of the right insular cortex; normal-to-mild atrophy of the left insular cortex; focal volume loss observed in the following subregions: central operculum (normal-to-mild atrophy on the left and mild atrophy on the right), anterior insula (mild atrophy on the left and normal on the right) and posterior insula (normal on the left and mild atrophy on the right) - mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: parahippocampal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), entorhinal area (mild atrophy on the left and normal-to-mild atrophy on the right) and posterior cingulate gyrus (mild atrophy on the left and normal on the right) - no clear atrophic alterations are visible in the frontal lobe - the temporal lobe shows no notable changes suggestive of atrophy - the parietal lobe shows no notable changes suggestive of atrophy
AD
FTLD_203656054_03455_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450768
On a T1-weighted brain MRI we observed: For the ventricles: - no observable enlargement of the 4th ventricle - mild enlargement of the right lateral ventricle; normal-to-mild enlargement of the left lateral ventricle - severe bilateral enlargement of the inf. lateral ventricle - mild enlargement of the 3rd ventricle - mild enlargement of the external csf For the subcortical structures: - severe bilateral atrophy of the amygdala - mild atrophy of the right accumbens; the left accumbens is normal - no findings suggestive of atrophy are seen in the basal forebrain - mild bilateral atrophy of the thalamus - mild-to-moderate atrophy of the left hippocampus - moderate-to-severe atrophy of the right hippocampus - no evident atrophy or tissue thinning seen in the caudate - no findings suggestive of atrophy are seen in the putamen - no observable atrophic changes in the pallidum - no evident atrophy or tissue thinning seen in the ventral dc For the cerebral cortex: - no observable atrophic changes in the occipital lobe - no findings suggestive of atrophy are seen in the limbic cortex - no clear atrophic alterations are visible in the parietal lobe - frontal lobe appears within normal limits without apparent atrophy - moderate atrophy of the left insular cortex and moderate-to-severe atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and moderate-to-severe atrophy on the right), posterior insula (mild atrophy on the left and mild-to-moderate atrophy on the right), parietal operculum (mild atrophy both left/right) and frontal operculum (normal-to-mild atrophy on the left and mild atrophy on the right) - moderate-to-severe atrophy of the left temporal lobe and severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate atrophy on the left and moderate-to-severe atrophy on the right), middle temporal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), inf. temporal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), planum temporale (mild atrophy both left/right), sup. temporal gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), transverse temporal gyrus (mild atrophy both left/right), fusiform gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right) and planum polare (normal-to-mild atrophy on the left and mild atrophy on the right)
SV
ADNI_941_S_10135_MR_Accelerated_Sagittal_MPRAGE_MSV21_br_raw_20240627183647610_1_I10676975
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no observable atrophic changes in the parietal lobe - no clear atrophic alterations are visible in the frontal lobe - temporal lobe maintains a normal appearance with no observable atrophic features - the limbic cortex shows no notable changes suggestive of atrophy - no findings suggestive of atrophy are seen in the occipital lobe - insular cortex maintains a normal appearance with no observable atrophic features For the subcortical structures: - caudate demonstrates a healthy morphology without signs of atrophy - moderate atrophy of the right amygdala; normal-to-mild atrophy of the left amygdala - no clear atrophic alterations are visible in the basal forebrain - no evident atrophy or tissue thinning seen in the ventral dc - thalamus demonstrates a healthy morphology without signs of atrophy - no clear atrophic alterations are visible in the hippocampus - no evident atrophy or tissue thinning seen in the putamen - the accumbens shows no notable changes suggestive of atrophy - no observable atrophic changes in the pallidum For the ventricles: - no clear enlargement or abnormal growth seen in the inf. lateral ventricle - no clear enlargement or abnormal growth seen in the lateral ventricle - no appreciable enlargement noted in the 3rd ventricle - no clear enlargement or abnormal growth seen in the 4th ventricle - no evident size increase noted in the external csf
AD
FTLD_203628476_03672_MR_Accelerated_Sagittal_IR-FSPGR_br_raw_202_I10451045
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild atrophy of the right amygdala; normal-to-mild atrophy of the left amygdala - moderate atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens - mild-to-moderate atrophy of the left thalamus and mild atrophy of the right thalamus - basal forebrain maintains a normal appearance with no observable atrophic features - moderate-to-severe atrophy of the left pallidum and mild atrophy of the right pallidum - the left hippocampus volume is borderline low - the left hippocampus volume is borderline low - mild-to-moderate atrophy of the left ventral dc and mild atrophy of the right ventral dc - moderate atrophy of the left caudate and mild-to-moderate atrophy of the right caudate - mild-to-moderate atrophy of the left putamen and mild atrophy of the right putamen For the ventricles: - mild-to-moderate bilateral enlargement of the lateral ventricle - mild-to-moderate enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle - 4th ventricle maintains its expected proportions without signs of enlargement - mild-to-moderate enlargement of the 3rd ventricle - mild enlargement of the external csf For the cerebral cortex: - insular cortex demonstrates a healthy morphology without signs of atrophy - no clear atrophic alterations are visible in the frontal lobe - mild atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: sup. temporal gyrus (mild atrophy on the left), planum temporale (moderate atrophy on the left and normal on the right), transverse temporal gyrus (mild atrophy on the left) and temporal pole (mild atrophy on the left and normal on the right) - no findings suggestive of atrophy are seen in the limbic cortex - no appreciable degenerative or atrophic changes observed in the occipital lobe - mild atrophy of the left parietal lobe; the right parietal lobe is normal
PNFA
ADNI_019_S_10263_MR_Sagittal_3D_Accelerated_MPRAGE_MSV21_br_raw_20241025184332414_1_I10989649
On a T1-weighted brain MRI we observed: For the ventricles: - no evident size increase noted in the inf. lateral ventricle - mild-to-moderate enlargement of the external csf - mild enlargement of the right lateral ventricle; normal-to-mild enlargement of the left lateral ventricle - no observable enlargement of the 3rd ventricle - 4th ventricle appears to be of normal dimensions, with no observable increase in size For the cerebral cortex: - the occipital lobe shows no notable changes suggestive of atrophy - no appreciable degenerative or atrophic changes observed in the temporal lobe - frontal lobe maintains a normal appearance with no observable atrophic features - parietal lobe demonstrates a healthy morphology without signs of atrophy - no appreciable degenerative or atrophic changes observed in the insular cortex - no evident atrophy or tissue thinning seen in the limbic cortex For the subcortical structures: - mild bilateral atrophy of the thalamus - mild-to-moderate atrophy of the left ventral dc and mild atrophy of the right ventral dc - no findings suggestive of atrophy are seen in the hippocampus - caudate appears preserved, with no observable tissue loss - mild atrophy of the left amygdala; normal-to-mild atrophy of the right amygdala - basal forebrain appears preserved, with no observable tissue loss - mild atrophy of the left putamen; normal-to-mild atrophy of the right putamen - moderate atrophy of the left pallidum and mild-to-moderate atrophy of the right pallidum - accumbens appears preserved, with no observable tissue loss
CN
ADNI_016_S_6839_MR_Accelerated_Sagittal_MPRAGE__br_raw_20191207184545003_53_S902460_I1263249
On a T1-weighted brain MRI we observed: For the cerebral cortex: - parietal lobe appears within normal limits without apparent atrophy - no appreciable degenerative or atrophic changes observed in the occipital lobe - no observable atrophic changes in the frontal lobe - mild atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: temporal pole (mild atrophy on the left and normal on the right) and fusiform gyrus (mild atrophy on the left) - mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (mild atrophy both left/right) and anterior cingulate gyrus (mild-to-moderate atrophy on the left and normal on the right) - insular cortex demonstrates a healthy morphology without signs of atrophy For the subcortical structures: - mild-to-moderate bilateral atrophy of the amygdala - mild atrophy of the left pallidum; the right pallidum is normal - mild atrophy of the left caudate; the right caudate is normal - mild atrophy of the left hippocampus - mild-to-moderate atrophy of the right hippocampus - mild bilateral atrophy of the thalamus - mild-to-moderate atrophy of the left accumbens and mild atrophy of the right accumbens - basal forebrain appears within normal limits without apparent atrophy - moderate atrophy of the left putamen and mild-to-moderate atrophy of the right putamen - mild atrophy of the right ventral dc; normal-to-mild atrophy of the left ventral dc For the ventricles: - mild-to-moderate enlargement of the left lateral ventricle and moderate enlargement of the right lateral ventricle - mild enlargement of the 3rd ventricle - moderate bilateral enlargement of the inf. lateral ventricle - mild enlargement of the 4th ventricle - mild enlargement of the external csf
AD
ADNI_037_S_6204_MR_Accelerated_Sagittal_MPRAGE__br_raw_20180309150302002_2_S665435_I971779
On a T1-weighted brain MRI we observed: For the ventricles: - no evident size increase noted in the lateral ventricle - no findings suggestive of enlargement are seen in the inf. lateral ventricle - mild enlargement of the external csf - 4th ventricle maintains its expected proportions without signs of enlargement - 3rd ventricle maintains a typical volume without observable enlargement For the subcortical structures: - no clear atrophic alterations are visible in the accumbens - thalamus appears within normal limits without apparent atrophy - no observable atrophic changes in the caudate - no appreciable degenerative or atrophic changes observed in the pallidum - putamen maintains a normal appearance with no observable atrophic features - ventral dc appears within normal limits without apparent atrophy - no findings suggestive of atrophy are seen in the hippocampus - no clear atrophic alterations are visible in the basal forebrain - mild atrophy of the left amygdala; normal-to-mild atrophy of the right amygdala For the cerebral cortex: - no findings suggestive of atrophy are seen in the insular cortex - no findings suggestive of atrophy are seen in the temporal lobe - frontal lobe appears within normal limits without apparent atrophy - occipital lobe demonstrates a healthy morphology without signs of atrophy - mild atrophy of the right limbic cortex; the left limbic cortex is normal - no observable atrophic changes in the parietal lobe
CN
ADNI_022_S_6822_MR_Accelerated_Sagittal_MPRAGE__br_raw_20191003115955882_158_S880344_I1236085
On a T1-weighted brain MRI we observed: For the ventricles: - no observable enlargement of the 4th ventricle - inf. lateral ventricle appears to be of normal dimensions, with no observable increase in size - no clear enlargement or abnormal growth seen in the 3rd ventricle - no appreciable enlargement noted in the external csf - no appreciable enlargement noted in the lateral ventricle For the cerebral cortex: - no findings suggestive of atrophy are seen in the occipital lobe - limbic cortex appears preserved, with no observable tissue loss - insular cortex appears preserved, with no observable tissue loss - parietal lobe appears within normal limits without apparent atrophy - frontal lobe appears preserved, with no observable tissue loss - temporal lobe appears preserved, with no observable tissue loss For the subcortical structures: - no findings suggestive of atrophy are seen in the caudate - ventral dc demonstrates a healthy morphology without signs of atrophy - no evident atrophy or tissue thinning seen in the hippocampus - accumbens maintains a normal appearance with no observable atrophic features - no observable atrophic changes in the putamen - basal forebrain demonstrates a healthy morphology without signs of atrophy - no evident atrophy or tissue thinning seen in the pallidum - no evident atrophy or tissue thinning seen in the amygdala - thalamus maintains a normal appearance with no observable atrophic features
CN
FTLD_203583009_01908_MR_Accelerated_Sagittal_MPRAGE_TEST_br_raw_2_I10449490
On a T1-weighted brain MRI we observed: For the ventricles: - severe bilateral enlargement of the inf. lateral ventricle - no findings suggestive of enlargement are seen in the 4th ventricle - mild enlargement of the 3rd ventricle - mild-to-moderate enlargement of the external csf - severe bilateral enlargement of the lateral ventricle For the subcortical structures: - no clear atrophic alterations are visible in the ventral dc - mild bilateral atrophy of the thalamus - severe bilateral atrophy of the putamen - severe bilateral atrophy of the amygdala - moderate atrophy of the left pallidum and moderate-to-severe atrophy of the right pallidum - moderate atrophy of the left hippocampus - severe atrophy of the right hippocampus - no findings suggestive of atrophy are seen in the basal forebrain - severe bilateral atrophy of the caudate - severe bilateral atrophy of the accumbens For the cerebral cortex: - severe bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: middle temporal gyrus (moderate-to-severe atrophy both left/right), temporal pole (moderate atrophy on the left and severe atrophy on the right), fusiform gyrus (mild-to-moderate atrophy on the left and moderate atrophy on the right), inf. temporal gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), planum polare (mild-to-moderate atrophy both left/right) and sup. temporal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right) - parietal lobe demonstrates a healthy morphology without signs of atrophy - mild atrophy of the left insular cortex and mild-to-moderate atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and moderate atrophy on the right) and posterior insula (mild-to-moderate atrophy both left/right) - mild atrophy of the left frontal lobe and mild-to-moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), gyrus rectus (mild atrophy both left/right), medial orbital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), precentral gyrus medial segment (normal-to-mild atrophy on the left and mild atrophy on the right), frontal pole (normal on the left and mild atrophy on the right), anterior orbital gyrus (mild atrophy on the left and normal on the right) and sup. frontal gyrus (normal on the left and mild atrophy on the right) - occipital lobe appears within normal limits without apparent atrophy - moderate bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: entorhinal area (moderate atrophy both left/right), parahippocampal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), anterior cingulate gyrus (mild atrophy both left/right) and middle cingulate gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right)
SV
ADNI_073_S_4777_MR_MT1__N3m_Br_20161213124755622_S515237_I800044
On a T1-weighted brain MRI we observed: For the ventricles: - 4th ventricle maintains a typical volume without observable enlargement - mild-to-moderate enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle - external csf appears within normal size limits with no apparent enlargement - 3rd ventricle maintains a typical volume without observable enlargement - the lateral ventricle shows no notable changes suggestive of enlargement For the cerebral cortex: - no evident atrophy or tissue thinning seen in the limbic cortex - frontal lobe appears within normal limits without apparent atrophy - no observable atrophic changes in the parietal lobe - no observable atrophic changes in the occipital lobe - insular cortex maintains a normal appearance with no observable atrophic features - mild atrophy of the left temporal lobe; normal-to-mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: fusiform gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right) and transverse temporal gyrus (mild atrophy both left/right) For the subcortical structures: - mild-to-moderate atrophy of the left hippocampus - mild atrophy of the right hippocampus - no findings suggestive of atrophy are seen in the putamen - no findings suggestive of atrophy are seen in the ventral dc - no appreciable degenerative or atrophic changes observed in the thalamus - pallidum demonstrates a healthy morphology without signs of atrophy - basal forebrain demonstrates a healthy morphology without signs of atrophy - no evident atrophy or tissue thinning seen in the amygdala - caudate appears preserved, with no observable tissue loss - no appreciable degenerative or atrophic changes observed in the accumbens
AD
ADNI_041_S_6401_MR_Accelerated_Sagittal_MPRAGE__br_raw_20180612161506575_37_S694592_I1008726
On a T1-weighted brain MRI we observed: For the ventricles: - no observable enlargement of the 3rd ventricle - 4th ventricle appears within normal size limits with no apparent enlargement - external csf maintains a typical volume without observable enlargement - no appreciable enlargement noted in the lateral ventricle - inf. lateral ventricle appears within normal size limits with no apparent enlargement For the subcortical structures: - mild atrophy of the left putamen; normal-to-mild atrophy of the right putamen - no observable atrophic changes in the pallidum - the amygdala shows no notable changes suggestive of atrophy - thalamus appears within normal limits without apparent atrophy - no observable atrophic changes in the caudate - no appreciable degenerative or atrophic changes observed in the hippocampus - accumbens appears within normal limits without apparent atrophy - no findings suggestive of atrophy are seen in the ventral dc - mild atrophy of the left basal forebrain; the right basal forebrain is normal For the cerebral cortex: - no clear atrophic alterations are visible in the limbic cortex - frontal lobe maintains a normal appearance with no observable atrophic features - no findings suggestive of atrophy are seen in the parietal lobe - no findings suggestive of atrophy are seen in the occipital lobe - insular cortex maintains a normal appearance with no observable atrophic features - no clear atrophic alterations are visible in the temporal lobe
CN
FTLD_203117063_03361_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10176826
On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild-to-moderate atrophy of the left limbic cortex; normal-to-mild atrophy of the right limbic cortex; focal volume loss observed in the following subregions: parahippocampal gyrus (moderate atrophy on the left), anterior cingulate gyrus (mild atrophy both left/right) and middle cingulate gyrus (normal on the left and mild atrophy on the right) - moderate atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: gyrus rectus (normal-to-mild atrophy on the left and mild atrophy on the right), opercular inf. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), sup. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), supplementary motor cortex (mild atrophy on the left), frontal pole (mild atrophy on the left and normal on the right), middle frontal gyrus (mild atrophy on the left and normal on the right), anterior orbital gyrus (mild atrophy on the left) and sup. frontal gyrus medial segment (mild atrophy on the left) - no appreciable degenerative or atrophic changes observed in the occipital lobe - severe atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: sup. temporal gyrus (moderate atrophy on the left and mild atrophy on the right), middle temporal gyrus (moderate atrophy on the left and normal on the right), temporal pole (moderate atrophy on the left and normal on the right), planum temporale (mild atrophy both left/right), fusiform gyrus (mild-to-moderate atrophy on the left and normal on the right), planum polare (mild-to-moderate atrophy on the left and normal on the right), inf. temporal gyrus (mild-to-moderate atrophy on the left and normal on the right) and transverse temporal gyrus (mild atrophy on the left and normal on the right) - moderate-to-severe atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and normal-to-mild atrophy on the right), posterior insula (mild-to-moderate atrophy on the left and mild atrophy on the right), frontal operculum (mild atrophy both left/right), parietal operculum (mild atrophy on the left and normal-to-mild atrophy on the right) and central operculum (mild-to-moderate atrophy on the left) - the parietal lobe shows no notable changes suggestive of atrophy For the ventricles: - moderate enlargement of the 3rd ventricle - severe enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal - moderate enlargement of the external csf - 4th ventricle appears to be of normal dimensions, with no observable increase in size - moderate-to-severe enlargement of the left lateral ventricle and mild enlargement of the right lateral ventricle For the subcortical structures: - severe atrophy of the left hippocampus - moderate atrophy of the right hippocampus - severe atrophy of the left thalamus; the right thalamus is normal - the basal forebrain shows no notable changes suggestive of atrophy - moderate-to-severe atrophy of the left amygdala; normal-to-mild atrophy of the right amygdala - moderate atrophy of the left caudate and mild atrophy of the right caudate - moderate atrophy of the left pallidum; normal-to-mild atrophy of the right pallidum - severe atrophy of the left putamen and mild-to-moderate atrophy of the right putamen - mild-to-moderate atrophy of the left ventral dc; normal-to-mild atrophy of the right ventral dc - moderate atrophy of the left accumbens and mild atrophy of the right accumbens
SV
ADNI_011_S_10041_MR_Accelerated_Sagittal_MPRAGE_MSV21_br_raw_20240517083516647_1_I10460262
On a T1-weighted brain MRI we observed: For the ventricles: - no findings suggestive of enlargement are seen in the 4th ventricle - no appreciable enlargement noted in the 3rd ventricle - inf. lateral ventricle appears within normal size limits with no apparent enlargement - no clear enlargement or abnormal growth seen in the external csf - lateral ventricle maintains its expected proportions without signs of enlargement For the subcortical structures: - no findings suggestive of atrophy are seen in the basal forebrain - the hippocampus shows no notable changes suggestive of atrophy - mild-to-moderate bilateral atrophy of the putamen - no appreciable degenerative or atrophic changes observed in the caudate - no observable atrophic changes in the ventral dc - mild atrophy of the right accumbens; the left accumbens is normal - amygdala demonstrates a healthy morphology without signs of atrophy - no observable atrophic changes in the thalamus - pallidum maintains a normal appearance with no observable atrophic features For the cerebral cortex: - parietal lobe demonstrates a healthy morphology without signs of atrophy - mild atrophy of the left temporal lobe; normal-to-mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: middle temporal gyrus (mild atrophy on the left and normal on the right) - no clear atrophic alterations are visible in the occipital lobe; focal volume loss observed in the following subregions: inf. occipital gyrus (mild atrophy both left/right) and lingual gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) - frontal lobe appears within normal limits without apparent atrophy - insular cortex maintains a normal appearance with no observable atrophic features - no appreciable degenerative or atrophic changes observed in the limbic cortex
CN
FTLD_203571477_02777_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178304
On a T1-weighted brain MRI we observed: For the ventricles: - lateral ventricle maintains its expected proportions without signs of enlargement - no evident size increase noted in the 4th ventricle - no findings suggestive of enlargement are seen in the 3rd ventricle - severe bilateral enlargement of the inf. lateral ventricle - moderate enlargement of the external csf For the subcortical structures: - the basal forebrain shows no notable changes suggestive of atrophy - mild-to-moderate atrophy of the left accumbens and mild atrophy of the right accumbens - moderate atrophy of the left hippocampus - mild atrophy of the right hippocampus - moderate-to-severe atrophy of the left putamen and mild atrophy of the right putamen - severe bilateral atrophy of the amygdala - no evident atrophy or tissue thinning seen in the pallidum - no observable atrophic changes in the ventral dc - mild atrophy of the left caudate; normal-to-mild atrophy of the right caudate - thalamus maintains a normal appearance with no observable atrophic features For the cerebral cortex: - mild-to-moderate bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: parahippocampal gyrus (moderate atrophy both left/right), entorhinal area (moderate atrophy on the left and mild-to-moderate atrophy on the right), anterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and middle cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) - no appreciable degenerative or atrophic changes observed in the parietal lobe - no observable atrophic changes in the occipital lobe - no appreciable degenerative or atrophic changes observed in the frontal lobe - severe atrophy of the left temporal lobe and moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), inf. temporal gyrus (moderate-to-severe atrophy on the left and mild atrophy on the right), fusiform gyrus (moderate atrophy on the left and mild atrophy on the right), middle temporal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), sup. temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and planum polare (mild atrophy on the left and normal on the right) - mild-to-moderate atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and mild atrophy on the right), posterior insula (mild-to-moderate atrophy on the left and mild atrophy on the right) and frontal operculum (normal-to-mild atrophy on the left and mild atrophy on the right)
SV
ADNI_031_S_4024_MR_MPRAGE_br_raw_20110425135648715_88_S105088_I228879
On a T1-weighted brain MRI we observed: For the subcortical structures: - no clear atrophic alterations are visible in the thalamus - the caudate shows no notable changes suggestive of atrophy - mild atrophy of the left hippocampus - mild atrophy of the right hippocampus - no observable atrophic changes in the ventral dc - no observable atrophic changes in the accumbens - basal forebrain maintains a normal appearance with no observable atrophic features - no findings suggestive of atrophy are seen in the pallidum - putamen appears preserved, with no observable tissue loss - mild-to-moderate atrophy of the left amygdala and mild atrophy of the right amygdala For the ventricles: - 3rd ventricle appears within normal size limits with no apparent enlargement - no findings suggestive of enlargement are seen in the 4th ventricle - inf. lateral ventricle maintains its expected proportions without signs of enlargement - no evident size increase noted in the external csf - mild enlargement of the left lateral ventricle and moderate enlargement of the right lateral ventricle For the cerebral cortex: - mild bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: middle temporal gyrus (mild atrophy both left/right) and inf. temporal gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) - limbic cortex appears preserved, with no observable tissue loss - mild atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: sup. frontal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), opercular inf. frontal gyrus (normal on the left and mild atrophy on the right), medial frontal cortex (mild atrophy on the left) and posterior orbital gyrus (normal on the left and mild atrophy on the right) - no observable atrophic changes in the occipital lobe - mild atrophy of the left parietal lobe; normal-to-mild atrophy of the right parietal lobe; focal volume loss observed in the following subregions: angular gyrus (normal on the left and mild atrophy on the right) and sup. parietal lobule (mild atrophy on the left and normal on the right) - insular cortex appears preserved, with no observable tissue loss
AD
ADNI_012_S_5121_MR_MPRAGE_br_raw_20150508113643289_1_S258850_I491410
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no evident atrophy or tissue thinning seen in the occipital lobe - no findings suggestive of atrophy are seen in the limbic cortex - temporal lobe appears within normal limits without apparent atrophy - no evident atrophy or tissue thinning seen in the insular cortex - no observable atrophic changes in the frontal lobe - no observable atrophic changes in the parietal lobe For the subcortical structures: - mild bilateral atrophy of the pallidum - no observable atrophic changes in the caudate - no observable atrophic changes in the thalamus - mild bilateral atrophy of the accumbens - no appreciable degenerative or atrophic changes observed in the putamen - amygdala maintains a normal appearance with no observable atrophic features - basal forebrain maintains a normal appearance with no observable atrophic features - hippocampus appears within normal limits without apparent atrophy - mild atrophy of the right ventral dc; the left ventral dc is normal For the ventricles: - no appreciable enlargement noted in the 3rd ventricle - no evident size increase noted in the lateral ventricle - 4th ventricle appears to be of normal dimensions, with no observable increase in size - no findings suggestive of enlargement are seen in the external csf - no clear enlargement or abnormal growth seen in the inf. lateral ventricle
AD
FTLD_203590286_02689_MR_Accelerated_Sagittal_IR-FSPGR_br_raw_202_I10176953
On a T1-weighted brain MRI we observed: For the ventricles: - the lateral ventricle shows no notable changes suggestive of enlargement - no evident size increase noted in the 4th ventricle - inf. lateral ventricle appears within normal size limits with no apparent enlargement - 3rd ventricle maintains a typical volume without observable enlargement - no observable enlargement of the external csf For the subcortical structures: - no clear atrophic alterations are visible in the basal forebrain - no findings suggestive of atrophy are seen in the thalamus - the hippocampus shows no notable changes suggestive of atrophy - mild bilateral atrophy of the caudate - no findings suggestive of atrophy are seen in the amygdala - the ventral dc shows no notable changes suggestive of atrophy - pallidum demonstrates a healthy morphology without signs of atrophy - mild atrophy of the left accumbens; the right accumbens is normal - putamen maintains a normal appearance with no observable atrophic features For the cerebral cortex: - no appreciable degenerative or atrophic changes observed in the parietal lobe - mild atrophy of the right temporal lobe; normal-to-mild atrophy of the left temporal lobe; focal volume loss observed in the following subregions: temporal pole (mild atrophy both left/right) and sup. temporal gyrus (mild atrophy on the left and normal on the right) - no findings suggestive of atrophy are seen in the occipital lobe - no clear atrophic alterations are visible in the limbic cortex - insular cortex appears within normal limits without apparent atrophy - frontal lobe appears preserved, with no observable tissue loss
PNFA
FTLD_203519649_02941_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177147
On a T1-weighted brain MRI we observed: For the ventricles: - mild enlargement of the external csf - the 4th ventricle shows no notable changes suggestive of enlargement - inf. lateral ventricle maintains its expected proportions without signs of enlargement - mild enlargement of the 3rd ventricle - no observable enlargement of the lateral ventricle For the cerebral cortex: - limbic cortex maintains a normal appearance with no observable atrophic features - insular cortex appears preserved, with no observable tissue loss - no observable atrophic changes in the parietal lobe - frontal lobe appears preserved, with no observable tissue loss - occipital lobe maintains a normal appearance with no observable atrophic features - no findings suggestive of atrophy are seen in the temporal lobe For the subcortical structures: - no appreciable degenerative or atrophic changes observed in the thalamus - no clear atrophic alterations are visible in the caudate - ventral dc appears preserved, with no observable tissue loss - no clear atrophic alterations are visible in the putamen - mild atrophy of the right hippocampus - no clear atrophic alterations are visible in the basal forebrain - mild bilateral atrophy of the pallidum - moderate atrophy of the left accumbens and mild atrophy of the right accumbens - mild bilateral atrophy of the amygdala
BV
ADNI_018_S_4257_MR_MPRAGE_br_raw_20111024133019140_57_S126108_I262076
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild-to-moderate atrophy of the left amygdala; the right amygdala is normal - mild atrophy of the left putamen; normal-to-mild atrophy of the right putamen - mild atrophy of the left hippocampus - basal forebrain appears preserved, with no observable tissue loss - no appreciable degenerative or atrophic changes observed in the pallidum - thalamus appears within normal limits without apparent atrophy - ventral dc demonstrates a healthy morphology without signs of atrophy - accumbens appears preserved, with no observable tissue loss - no observable atrophic changes in the caudate For the cerebral cortex: - no evident atrophy or tissue thinning seen in the occipital lobe - frontal lobe appears preserved, with no observable tissue loss - parietal lobe maintains a normal appearance with no observable atrophic features - no evident atrophy or tissue thinning seen in the limbic cortex; focal volume loss observed in the following subregions: posterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) - no observable atrophic changes in the insular cortex - no findings suggestive of atrophy are seen in the temporal lobe For the ventricles: - external csf appears to be of normal dimensions, with no observable increase in size - no appreciable enlargement noted in the 4th ventricle - mild enlargement of the left lateral ventricle; the right lateral ventricle is normal - the 3rd ventricle shows no notable changes suggestive of enlargement - mild enlargement of the left inf. lateral ventricle; normal-to-mild enlargement of the right inf. lateral ventricle
CN