subject
stringlengths
64
104
txt_report
stringlengths
1.34k
4.06k
gold_diagnosis
stringclasses
5 values
FTLD_203207681_03180_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178283
On a T1-weighted brain MRI we observed: For the ventricles: - external csf appears within normal size limits with no apparent enlargement - moderate enlargement of the left inf. lateral ventricle; normal-to-mild enlargement of the right inf. lateral ventricle - moderate-to-severe enlargement of the left lateral ventricle and moderate enlargement of the right lateral ventricle - no appreciable enlargement noted in the 4th ventricle - no clear enlargement or abnormal growth seen in the 3rd ventricle For the cerebral cortex: - mild atrophy of the right limbic cortex; normal-to-mild atrophy of the left limbic cortex; focal volume loss observed in the following subregions: parahippocampal gyrus (mild atrophy both left/right), posterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and anterior cingulate gyrus (normal on the left and mild atrophy on the right) - moderate bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: central operculum (moderate atrophy on the left and mild-to-moderate atrophy on the right), parietal operculum (mild atrophy on the left and moderate atrophy on the right) and anterior insula (mild atrophy both left/right) - mild atrophy of the left parietal lobe; the right parietal lobe is normal; focal volume loss observed in the following subregions: precuneus (mild atrophy both left/right), angular gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), postcentral gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and supramarginal gyrus (mild atrophy on the left) - mild atrophy of the right temporal lobe; normal-to-mild atrophy of the left temporal lobe; focal volume loss observed in the following subregions: planum temporale (mild atrophy on the left and mild-to-moderate atrophy on the right) and sup. temporal gyrus (normal on the left and mild-to-moderate atrophy on the right) - the frontal lobe shows no notable changes suggestive of atrophy - no findings suggestive of atrophy are seen in the occipital lobe For the subcortical structures: - no clear atrophic alterations are visible in the ventral dc - caudate appears within normal limits without apparent atrophy - no appreciable degenerative or atrophic changes observed in the basal forebrain - no clear atrophic alterations are visible in the hippocampus - no appreciable degenerative or atrophic changes observed in the putamen - mild bilateral atrophy of the accumbens - no observable atrophic changes in the pallidum - the thalamus shows no notable changes suggestive of atrophy - mild atrophy of the left amygdala; normal-to-mild atrophy of the right amygdala
BV
ADNI_168_S_6561_MR_Accelerated_Sagittal_MPRAGE__br_raw_20180822163451957_35_S720326_I1040036
On a T1-weighted brain MRI we observed: For the subcortical structures: - no evident atrophy or tissue thinning seen in the basal forebrain - putamen maintains a normal appearance with no observable atrophic features - no findings suggestive of atrophy are seen in the hippocampus - no observable atrophic changes in the ventral dc - no appreciable degenerative or atrophic changes observed in the pallidum - no clear atrophic alterations are visible in the thalamus - no evident atrophy or tissue thinning seen in the amygdala - no clear atrophic alterations are visible in the caudate - no evident atrophy or tissue thinning seen in the accumbens For the ventricles: - lateral ventricle appears within normal size limits with no apparent enlargement - 3rd ventricle appears within normal size limits with no apparent enlargement - 4th ventricle maintains its expected proportions without signs of enlargement - no findings suggestive of enlargement are seen in the external csf - the inf. lateral ventricle shows no notable changes suggestive of enlargement For the cerebral cortex: - temporal lobe demonstrates a healthy morphology without signs of atrophy - no observable atrophic changes in the occipital lobe - no clear atrophic alterations are visible in the limbic cortex - no clear atrophic alterations are visible in the insular cortex - parietal lobe maintains a normal appearance with no observable atrophic features - no observable atrophic changes in the frontal lobe
CN
FTLD_203196400_02009_MR_Sagittal_MP-Rage_br_raw_20230209094406847_I10183255
On a T1-weighted brain MRI we observed: For the cerebral cortex: - the parietal lobe shows no notable changes suggestive of atrophy - mild-to-moderate atrophy of the left insular cortex and moderate atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (mild-to-moderate atrophy both left/right), central operculum (mild-to-moderate atrophy both left/right) and posterior insula (normal on the left and mild-to-moderate atrophy on the right) - mild atrophy of the left frontal lobe and mild-to-moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: posterior orbital gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), opercular inf. frontal gyrus (mild atrophy both left/right), orbital inf. frontal gyrus (mild atrophy both left/right), middle frontal gyrus (mild atrophy both left/right), gyrus rectus (mild atrophy on the left and normal-to-mild atrophy on the right), triangular inf. frontal gyrus (normal on the left and mild atrophy on the right), precentral gyrus (mild atrophy on the left and normal on the right), precentral gyrus medial segment (mild atrophy on the left and normal on the right) and sup. frontal gyrus medial segment (normal on the left and mild atrophy on the right) - mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy both left/right) and parahippocampal gyrus (mild atrophy on the left and normal on the right) - mild bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: transverse temporal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), temporal pole (normal-to-mild atrophy on the left and mild atrophy on the right), fusiform gyrus (mild atrophy on the left and normal on the right) and planum temporale (normal on the left and mild atrophy on the right) - occipital lobe appears preserved, with no observable tissue loss For the ventricles: - moderate-to-severe enlargement of the 3rd ventricle - moderate enlargement of the external csf - severe bilateral enlargement of the inf. lateral ventricle - severe enlargement of the 4th ventricle - severe bilateral enlargement of the lateral ventricle For the subcortical structures: - mild-to-moderate bilateral atrophy of the thalamus - basal forebrain appears preserved, with no observable tissue loss - moderate bilateral atrophy of the pallidum - mild bilateral atrophy of the ventral dc - severe bilateral atrophy of the caudate - the left hippocampus volume is borderline low - the left hippocampus volume is borderline low - moderate-to-severe atrophy of the left putamen and moderate atrophy of the right putamen - mild bilateral atrophy of the amygdala - moderate-to-severe bilateral atrophy of the accumbens
BV
ADNI_036_S_4740_MR_MPRAGE_br_raw_20120531115018775_6_S151616_I306469
On a T1-weighted brain MRI we observed: For the subcortical structures: - no appreciable degenerative or atrophic changes observed in the pallidum - putamen maintains a normal appearance with no observable atrophic features - mild-to-moderate atrophy of the left caudate and mild atrophy of the right caudate - moderate-to-severe atrophy of the left amygdala and mild atrophy of the right amygdala - mild bilateral atrophy of the basal forebrain - mild-to-moderate atrophy of the left hippocampus - mild atrophy of the right hippocampus - mild-to-moderate atrophy of the left ventral dc and mild atrophy of the right ventral dc - accumbens appears within normal limits without apparent atrophy - the thalamus shows no notable changes suggestive of atrophy For the ventricles: - mild-to-moderate enlargement of the left lateral ventricle and mild enlargement of the right lateral ventricle - mild-to-moderate enlargement of the left inf. lateral ventricle; normal-to-mild enlargement of the right inf. lateral ventricle - mild-to-moderate enlargement of the 4th ventricle - 3rd ventricle maintains its expected proportions without signs of enlargement - no observable enlargement of the external csf For the cerebral cortex: - mild atrophy of the right insular cortex; normal-to-mild atrophy of the left insular cortex; focal volume loss observed in the following subregions: parietal operculum (normal on the left and mild atrophy on the right) and posterior insula (normal on the left and mild atrophy on the right) - moderate atrophy of the left temporal lobe; normal-to-mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: transverse temporal gyrus (mild atrophy both left/right), middle temporal gyrus (mild-to-moderate atrophy on the left and normal on the right), sup. temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), planum temporale (mild atrophy on the left and normal on the right) and inf. temporal gyrus (mild atrophy on the left and normal on the right) - frontal lobe appears preserved, with no observable tissue loss - parietal lobe appears within normal limits without apparent atrophy - limbic cortex maintains a normal appearance with no observable atrophic features - occipital lobe appears within normal limits without apparent atrophy
AD
FTLD_203901165_02560_MR_Sagittal_MP-Rage_br_raw_20230209103425185_I10183512
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild atrophy of the right hippocampus - the amygdala shows no notable changes suggestive of atrophy - the putamen shows no notable changes suggestive of atrophy - mild bilateral atrophy of the caudate - thalamus maintains a normal appearance with no observable atrophic features - pallidum maintains a normal appearance with no observable atrophic features - no appreciable degenerative or atrophic changes observed in the ventral dc - basal forebrain maintains a normal appearance with no observable atrophic features - no clear atrophic alterations are visible in the accumbens For the cerebral cortex: - the frontal lobe shows no notable changes suggestive of atrophy - insular cortex appears within normal limits without apparent atrophy - limbic cortex demonstrates a healthy morphology without signs of atrophy - temporal lobe appears within normal limits without apparent atrophy - occipital lobe demonstrates a healthy morphology without signs of atrophy - the parietal lobe shows no notable changes suggestive of atrophy For the ventricles: - 3rd ventricle maintains its expected proportions without signs of enlargement - inf. lateral ventricle maintains a typical volume without observable enlargement - mild enlargement of the 4th ventricle - no evident size increase noted in the external csf - no appreciable enlargement noted in the lateral ventricle
CN
FTLD_203160043_01346_MR_Sagittal_MP-Rage_br_raw_20230206140338189_I10181124
On a T1-weighted brain MRI we observed: For the subcortical structures: - putamen appears preserved, with no observable tissue loss - mild atrophy of the right caudate; the left caudate is normal - the left hippocampus volume is borderline low - the left hippocampus volume is borderline low - pallidum appears within normal limits without apparent atrophy - no clear atrophic alterations are visible in the basal forebrain - the accumbens shows no notable changes suggestive of atrophy - amygdala appears within normal limits without apparent atrophy - the thalamus shows no notable changes suggestive of atrophy - ventral dc appears preserved, with no observable tissue loss For the ventricles: - mild-to-moderate enlargement of the 3rd ventricle - no observable enlargement of the external csf - 4th ventricle appears to be of normal dimensions, with no observable increase in size - mild enlargement of the left lateral ventricle and moderate enlargement of the right lateral ventricle - mild bilateral enlargement of the inf. lateral ventricle For the cerebral cortex: - no evident atrophy or tissue thinning seen in the temporal lobe - parietal lobe appears within normal limits without apparent atrophy - no clear atrophic alterations are visible in the limbic cortex - mild atrophy of the right frontal lobe; the left frontal lobe is normal; focal volume loss observed in the following subregions: precentral gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), sup. frontal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right) and precentral gyrus medial segment (mild-to-moderate atrophy on the left) - occipital lobe appears preserved, with no observable tissue loss - insular cortex demonstrates a healthy morphology without signs of atrophy
PNFA
ADNI_035_S_6927_MR_Accelerated_Sagittal_MPRAGE_Phase_A-P__br_raw_20220727095314231_205_S1150655_I1609469
On a T1-weighted brain MRI we observed: For the ventricles: - mild bilateral enlargement of the inf. lateral ventricle - no appreciable enlargement noted in the 4th ventricle - mild enlargement of the left lateral ventricle; normal-to-mild enlargement of the right lateral ventricle - the 3rd ventricle shows no notable changes suggestive of enlargement - no appreciable enlargement noted in the external csf For the cerebral cortex: - no findings suggestive of atrophy are seen in the limbic cortex - temporal lobe appears preserved, with no observable tissue loss - no clear atrophic alterations are visible in the occipital lobe - mild atrophy of the right parietal lobe; the left parietal lobe is normal; focal volume loss observed in the following subregions: postcentral gyrus (mild atrophy on the right) and sup. parietal lobule (normal on the left and mild atrophy on the right) - no findings suggestive of atrophy are seen in the frontal lobe - no evident atrophy or tissue thinning seen in the insular cortex For the subcortical structures: - caudate demonstrates a healthy morphology without signs of atrophy - accumbens appears preserved, with no observable tissue loss - thalamus appears within normal limits without apparent atrophy - no evident atrophy or tissue thinning seen in the basal forebrain - no clear atrophic alterations are visible in the putamen - mild-to-moderate bilateral atrophy of the amygdala - the ventral dc shows no notable changes suggestive of atrophy - mild atrophy of the left hippocampus - mild atrophy of the right hippocampus - pallidum maintains a normal appearance with no observable atrophic features
AD
FTLD_203261907_03706_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10451087
On a T1-weighted brain MRI we observed: For the ventricles: - mild enlargement of the 4th ventricle - moderate-to-severe bilateral enlargement of the lateral ventricle - severe enlargement of the left inf. lateral ventricle and moderate enlargement of the right inf. lateral ventricle - mild-to-moderate enlargement of the 3rd ventricle - no appreciable enlargement noted in the external csf For the subcortical structures: - mild atrophy of the left thalamus; normal-to-mild atrophy of the right thalamus - mild atrophy of the left caudate; normal-to-mild atrophy of the right caudate - mild-to-moderate atrophy of the left pallidum and mild atrophy of the right pallidum - mild atrophy of the left hippocampus - the left hippocampus volume is borderline low - basal forebrain appears within normal limits without apparent atrophy - mild-to-moderate atrophy of the left putamen and mild atrophy of the right putamen - mild atrophy of the left amygdala; the right amygdala is normal - mild bilateral atrophy of the ventral dc - mild bilateral atrophy of the accumbens For the cerebral cortex: - mild atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: central operculum (mild atrophy both left/right) and parietal operculum (mild atrophy on the left and normal on the right) - no evident atrophy or tissue thinning seen in the occipital lobe - the temporal lobe shows no notable changes suggestive of atrophy - no evident atrophy or tissue thinning seen in the parietal lobe - frontal lobe appears preserved, with no observable tissue loss - no observable atrophic changes in the limbic cortex
BV
FTLD_203231766_02663_MR_Accelerated_Sagittal_MPRAGE_Repeat_br_raw_I10178175
On a T1-weighted brain MRI we observed: For the ventricles: - moderate enlargement of the external csf - lateral ventricle maintains its expected proportions without signs of enlargement - 4th ventricle maintains a typical volume without observable enlargement - 3rd ventricle maintains its expected proportions without signs of enlargement - moderate enlargement of the right inf. lateral ventricle; the left inf. lateral ventricle is normal For the cerebral cortex: - mild atrophy of the right frontal lobe; the left frontal lobe is normal; focal volume loss observed in the following subregions: subcallosal area (mild atrophy on the left and mild-to-moderate atrophy on the right), frontal pole (mild atrophy both left/right), gyrus rectus (mild atrophy both left/right) and middle frontal gyrus (normal on the left and mild atrophy on the right) - mild-to-moderate atrophy of the right insular cortex; the left insular cortex is normal; focal volume loss observed in the following subregions: posterior insula (mild-to-moderate atrophy on the left and moderate-to-severe atrophy on the right), anterior insula (normal on the left and moderate atrophy on the right) and frontal operculum (normal-to-mild atrophy on the left and mild atrophy on the right) - moderate atrophy of the left temporal lobe and severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: middle temporal gyrus (mild atrophy on the left and moderate-to-severe atrophy on the right), temporal pole (mild atrophy on the left and moderate-to-severe atrophy on the right), fusiform gyrus (mild-to-moderate atrophy both left/right), inf. temporal gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right) and sup. temporal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) - occipital lobe appears within normal limits without apparent atrophy - no evident atrophy or tissue thinning seen in the parietal lobe - mild-to-moderate bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: parahippocampal gyrus (mild-to-moderate atrophy on the left and moderate atrophy on the right), entorhinal area (mild atrophy on the left and moderate atrophy on the right), middle cingulate gyrus (mild atrophy both left/right) and anterior cingulate gyrus (mild atrophy on the left and normal on the right) For the subcortical structures: - mild atrophy of the right caudate; the left caudate is normal - no clear atrophic alterations are visible in the pallidum - no findings suggestive of atrophy are seen in the thalamus - moderate-to-severe atrophy of the left amygdala and severe atrophy of the right amygdala - basal forebrain appears within normal limits without apparent atrophy - mild-to-moderate atrophy of the right hippocampus - mild atrophy of the left accumbens and moderate atrophy of the right accumbens - mild atrophy of the right putamen; normal-to-mild atrophy of the left putamen - no clear atrophic alterations are visible in the ventral dc
SV
FTLD_203792827_02729_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10176876
On a T1-weighted brain MRI we observed: For the ventricles: - 3rd ventricle appears within normal size limits with no apparent enlargement - the 4th ventricle shows no notable changes suggestive of enlargement - moderate-to-severe enlargement of the external csf - moderate-to-severe enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle - moderate-to-severe enlargement of the left lateral ventricle and severe enlargement of the right lateral ventricle For the subcortical structures: - mild atrophy of the left hippocampus - mild atrophy of the right hippocampus - no appreciable degenerative or atrophic changes observed in the basal forebrain - severe atrophy of the left caudate and moderate atrophy of the right caudate - moderate-to-severe atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens - moderate-to-severe atrophy of the left amygdala and mild-to-moderate atrophy of the right amygdala - severe atrophy of the left putamen and mild-to-moderate atrophy of the right putamen - moderate atrophy of the left pallidum and mild atrophy of the right pallidum - mild atrophy of the left thalamus; the right thalamus is normal - mild bilateral atrophy of the ventral dc For the cerebral cortex: - no findings suggestive of atrophy are seen in the parietal lobe - moderate-to-severe atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (severe atrophy on the left and normal-to-mild atrophy on the right), frontal operculum (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), central operculum (mild atrophy both left/right) and parietal operculum (mild atrophy on the left) - occipital lobe appears preserved, with no observable tissue loss - severe atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: triangular inf. frontal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), opercular inf. frontal gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), middle frontal gyrus (moderate atrophy on the left), sup. frontal gyrus (moderate atrophy on the left), lateral orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), orbital inf. frontal gyrus (mild atrophy on the left), posterior orbital gyrus (mild atrophy on the left and normal on the right), precentral gyrus (mild atrophy on the left) and sup. frontal gyrus medial segment (mild atrophy on the left) - moderate atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy on the left and mild atrophy on the right), middle temporal gyrus (moderate-to-severe atrophy on the left) and planum polare (normal-to-mild atrophy on the left and mild atrophy on the right) - mild-to-moderate atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (moderate atrophy on the left and mild atrophy on the right) and parahippocampal gyrus (mild atrophy on the left)
BV
FTLD_203280469_02968_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178105
On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild-to-moderate atrophy of the left frontal lobe and severe atrophy of the right frontal lobe; focal volume loss observed in the following subregions: gyrus rectus (moderate-to-severe atrophy both left/right), medial orbital gyrus (moderate atrophy on the left and moderate-to-severe atrophy on the right), sup. frontal gyrus (mild-to-moderate atrophy on the left and moderate-to-severe atrophy on the right), medial frontal cortex (mild-to-moderate atrophy on the left and moderate atrophy on the right), sup. frontal gyrus medial segment (mild atrophy on the left and moderate-to-severe atrophy on the right), posterior orbital gyrus (mild-to-moderate atrophy both left/right), frontal pole (normal-to-mild atrophy on the left and moderate atrophy on the right), anterior orbital gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), lateral orbital gyrus (mild atrophy both left/right), supplementary motor cortex (mild atrophy both left/right), middle frontal gyrus (moderate atrophy on the right), subcallosal area (mild atrophy both left/right), triangular inf. frontal gyrus (normal on the left and mild atrophy on the right) and orbital inf. frontal gyrus (mild atrophy on the left) - mild atrophy of the left insular cortex and mild-to-moderate atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and severe atrophy on the right), posterior insula (mild-to-moderate atrophy on the left and normal on the right) and frontal operculum (normal on the left and mild-to-moderate atrophy on the right) - occipital lobe appears preserved, with no observable tissue loss - moderate bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: entorhinal area (moderate atrophy both left/right), anterior cingulate gyrus (moderate atrophy on the left and mild atrophy on the right), middle cingulate gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and parahippocampal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) - no observable atrophic changes in the parietal lobe - moderate-to-severe atrophy of the left temporal lobe and severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: middle temporal gyrus (moderate atrophy on the left and severe atrophy on the right), temporal pole (moderate-to-severe atrophy both left/right), inf. temporal gyrus (mild atrophy on the left and moderate atrophy on the right) and fusiform gyrus (mild atrophy both left/right) For the ventricles: - mild-to-moderate enlargement of the left lateral ventricle and moderate-to-severe enlargement of the right lateral ventricle - mild-to-moderate enlargement of the 3rd ventricle - moderate-to-severe enlargement of the external csf - no observable enlargement of the 4th ventricle - mild enlargement of the left inf. lateral ventricle and mild-to-moderate enlargement of the right inf. lateral ventricle For the subcortical structures: - moderate atrophy of the left putamen and moderate-to-severe atrophy of the right putamen - severe bilateral atrophy of the amygdala - moderate atrophy of the left caudate and severe atrophy of the right caudate - severe bilateral atrophy of the accumbens - the ventral dc shows no notable changes suggestive of atrophy - mild bilateral atrophy of the thalamus - mild-to-moderate atrophy of the left hippocampus - mild-to-moderate atrophy of the right hippocampus - mild-to-moderate atrophy of the right pallidum; the left pallidum is normal - basal forebrain demonstrates a healthy morphology without signs of atrophy
BV
ADNI_024_S_5290_MR_MPRAGE_br_raw_20130909185058757_145_S200104_I388957
On a T1-weighted brain MRI we observed: For the subcortical structures: - ventral dc maintains a normal appearance with no observable atrophic features - no evident atrophy or tissue thinning seen in the hippocampus - no evident atrophy or tissue thinning seen in the basal forebrain - no findings suggestive of atrophy are seen in the pallidum - no clear atrophic alterations are visible in the putamen - no evident atrophy or tissue thinning seen in the thalamus - no clear atrophic alterations are visible in the accumbens - no findings suggestive of atrophy are seen in the caudate - no findings suggestive of atrophy are seen in the amygdala For the ventricles: - no findings suggestive of enlargement are seen in the lateral ventricle - no clear enlargement or abnormal growth seen in the 4th ventricle - mild enlargement of the external csf - no evident size increase noted in the 3rd ventricle - inf. lateral ventricle maintains its expected proportions without signs of enlargement For the cerebral cortex: - mild atrophy of the left limbic cortex; the right limbic cortex is normal - no appreciable degenerative or atrophic changes observed in the insular cortex - no observable atrophic changes in the temporal lobe - no evident atrophy or tissue thinning seen in the frontal lobe - no clear atrophic alterations are visible in the occipital lobe - parietal lobe appears preserved, with no observable tissue loss
CN
ADNI_033_S_10391_MR_Accelerated_Sagittal_MPRAGE_MSV21_br_raw_20250312185828252_1_I11152587
On a T1-weighted brain MRI we observed: For the subcortical structures: - no clear atrophic alterations are visible in the ventral dc - caudate appears within normal limits without apparent atrophy - no clear atrophic alterations are visible in the amygdala - no appreciable degenerative or atrophic changes observed in the basal forebrain - no findings suggestive of atrophy are seen in the accumbens - the putamen shows no notable changes suggestive of atrophy - hippocampus demonstrates a healthy morphology without signs of atrophy - thalamus appears within normal limits without apparent atrophy - pallidum maintains a normal appearance with no observable atrophic features For the ventricles: - external csf maintains a typical volume without observable enlargement - no clear enlargement or abnormal growth seen in the lateral ventricle - no clear enlargement or abnormal growth seen in the 3rd ventricle - no observable enlargement of the inf. lateral ventricle - 4th ventricle maintains its expected proportions without signs of enlargement For the cerebral cortex: - temporal lobe appears within normal limits without apparent atrophy - the frontal lobe shows no notable changes suggestive of atrophy - the parietal lobe shows no notable changes suggestive of atrophy - no findings suggestive of atrophy are seen in the insular cortex - no evident atrophy or tissue thinning seen in the limbic cortex - occipital lobe appears preserved, with no observable tissue loss
CN
ADNI_136_S_4993_MR_MPRAGE_br_raw_20121025150812723_51_S172271_I342522
On a T1-weighted brain MRI we observed: For the cerebral cortex: - temporal lobe maintains a normal appearance with no observable atrophic features - no evident atrophy or tissue thinning seen in the occipital lobe - limbic cortex demonstrates a healthy morphology without signs of atrophy - no appreciable degenerative or atrophic changes observed in the parietal lobe - frontal lobe appears preserved, with no observable tissue loss - insular cortex maintains a normal appearance with no observable atrophic features For the subcortical structures: - mild atrophy of the left basal forebrain; the right basal forebrain is normal - the left hippocampus volume is borderline low - no clear atrophic alterations are visible in the accumbens - caudate appears preserved, with no observable tissue loss - no findings suggestive of atrophy are seen in the pallidum - putamen appears preserved, with no observable tissue loss - ventral dc appears preserved, with no observable tissue loss - no observable atrophic changes in the amygdala - thalamus appears preserved, with no observable tissue loss For the ventricles: - mild enlargement of the left lateral ventricle; the right lateral ventricle is normal - moderate enlargement of the left inf. lateral ventricle; normal-to-mild enlargement of the right inf. lateral ventricle - external csf appears to be of normal dimensions, with no observable increase in size - 4th ventricle appears within normal size limits with no apparent enlargement - no observable enlargement of the 3rd ventricle
AD
FTLD_203447418_03814_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10451166
On a T1-weighted brain MRI we observed: For the subcortical structures: - pallidum maintains a normal appearance with no observable atrophic features - the ventral dc shows no notable changes suggestive of atrophy - severe atrophy of the left amygdala and mild-to-moderate atrophy of the right amygdala - thalamus maintains a normal appearance with no observable atrophic features - basal forebrain demonstrates a healthy morphology without signs of atrophy - mild atrophy of the left putamen; the right putamen is normal - caudate demonstrates a healthy morphology without signs of atrophy - mild atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens - moderate atrophy of the left hippocampus - mild atrophy of the right hippocampus For the ventricles: - mild bilateral enlargement of the lateral ventricle - 3rd ventricle maintains its expected proportions without signs of enlargement - severe enlargement of the left inf. lateral ventricle and moderate-to-severe enlargement of the right inf. lateral ventricle - external csf maintains its expected proportions without signs of enlargement - 4th ventricle appears within normal size limits with no apparent enlargement For the cerebral cortex: - occipital lobe maintains a normal appearance with no observable atrophic features - the frontal lobe shows no notable changes suggestive of atrophy - parietal lobe appears preserved, with no observable tissue loss - severe atrophy of the left temporal lobe and moderate-to-severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), middle temporal gyrus (moderate-to-severe atrophy on the left and mild atrophy on the right), inf. temporal gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), fusiform gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), planum temporale (mild atrophy on the left and mild-to-moderate atrophy on the right) and sup. temporal gyrus (mild atrophy on the left and normal on the right) - mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: parietal operculum (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), posterior insula (mild atrophy on the left) and central operculum (mild atrophy on the left and normal on the right) - limbic cortex demonstrates a healthy morphology without signs of atrophy
SV
FTLD_203590286_02689_MR_Accelerated_Sagittal_IR-FSPGR_br_raw_202_I10176953
On a T1-weighted brain MRI we observed: For the ventricles: - the external csf shows no notable changes suggestive of enlargement - no clear enlargement or abnormal growth seen in the 4th ventricle - no appreciable enlargement noted in the lateral ventricle - inf. lateral ventricle maintains a typical volume without observable enlargement - 3rd ventricle appears to be of normal dimensions, with no observable increase in size For the subcortical structures: - no observable atrophic changes in the thalamus - putamen maintains a normal appearance with no observable atrophic features - mild atrophy of the left accumbens; the right accumbens is normal - mild bilateral atrophy of the caudate - hippocampus appears within normal limits without apparent atrophy - no observable atrophic changes in the amygdala - pallidum appears preserved, with no observable tissue loss - ventral dc maintains a normal appearance with no observable atrophic features - no clear atrophic alterations are visible in the basal forebrain For the cerebral cortex: - no observable atrophic changes in the occipital lobe - insular cortex demonstrates a healthy morphology without signs of atrophy - parietal lobe appears preserved, with no observable tissue loss - mild atrophy of the right temporal lobe; normal-to-mild atrophy of the left temporal lobe; focal volume loss observed in the following subregions: temporal pole (mild atrophy both left/right) and sup. temporal gyrus (mild atrophy on the left and normal on the right) - frontal lobe demonstrates a healthy morphology without signs of atrophy - no observable atrophic changes in the limbic cortex
PNFA
FTLD_203014537_02731_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178217
On a T1-weighted brain MRI we observed: For the ventricles: - mild enlargement of the left lateral ventricle; normal-to-mild enlargement of the right lateral ventricle - 4th ventricle maintains a typical volume without observable enlargement - no observable enlargement of the external csf - no findings suggestive of enlargement are seen in the inf. lateral ventricle - no appreciable enlargement noted in the 3rd ventricle For the subcortical structures: - moderate atrophy of the left pallidum; the right pallidum is normal - no appreciable degenerative or atrophic changes observed in the thalamus - no clear atrophic alterations are visible in the hippocampus - mild atrophy of the left ventral dc; the right ventral dc is normal - no clear atrophic alterations are visible in the amygdala - caudate appears within normal limits without apparent atrophy - basal forebrain appears preserved, with no observable tissue loss - mild atrophy of the left putamen; the right putamen is normal - no findings suggestive of atrophy are seen in the accumbens For the cerebral cortex: - temporal lobe demonstrates a healthy morphology without signs of atrophy - limbic cortex appears preserved, with no observable tissue loss - mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (mild atrophy both left/right) - occipital lobe maintains a normal appearance with no observable atrophic features - parietal lobe demonstrates a healthy morphology without signs of atrophy - mild-to-moderate atrophy of the left frontal lobe and mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: precentral gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), middle frontal gyrus (mild atrophy both left/right), posterior orbital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), anterior orbital gyrus (mild atrophy on the left) and sup. frontal gyrus medial segment (normal on the left and mild atrophy on the right)
PNFA
ADNI_018_S_2155_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_20221121162905864_1_S1177447_I1644018
On a T1-weighted brain MRI we observed: For the subcortical structures: - ventral dc appears within normal limits without apparent atrophy - no clear atrophic alterations are visible in the basal forebrain - no evident atrophy or tissue thinning seen in the thalamus - caudate appears within normal limits without apparent atrophy - mild atrophy of the left amygdala and mild-to-moderate atrophy of the right amygdala - mild atrophy of the left hippocampus - mild-to-moderate atrophy of the right hippocampus - no evident atrophy or tissue thinning seen in the pallidum - accumbens demonstrates a healthy morphology without signs of atrophy - the putamen shows no notable changes suggestive of atrophy For the cerebral cortex: - mild atrophy of the left parietal lobe; normal-to-mild atrophy of the right parietal lobe; focal volume loss observed in the following subregions: angular gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) and postcentral gyrus medial segment (moderate atrophy on the left and normal on the right) - frontal lobe demonstrates a healthy morphology without signs of atrophy - no observable atrophic changes in the limbic cortex - no findings suggestive of atrophy are seen in the insular cortex - occipital lobe maintains a normal appearance with no observable atrophic features - no appreciable degenerative or atrophic changes observed in the temporal lobe For the ventricles: - the 4th ventricle shows no notable changes suggestive of enlargement - no appreciable enlargement noted in the external csf - no observable enlargement of the lateral ventricle - no evident size increase noted in the inf. lateral ventricle - no appreciable enlargement noted in the 3rd ventricle
AD
ADNI_003_S_1021_MR_MPR-R__GradWarp__B1_Correction__N3__Scaled_Br_20070918111516027_S21771_I73506
On a T1-weighted brain MRI we observed: For the ventricles: - no findings suggestive of enlargement are seen in the 3rd ventricle - inf. lateral ventricle maintains its expected proportions without signs of enlargement - no evident size increase noted in the lateral ventricle - 4th ventricle maintains its expected proportions without signs of enlargement - no evident size increase noted in the external csf For the cerebral cortex: - insular cortex maintains a normal appearance with no observable atrophic features - temporal lobe demonstrates a healthy morphology without signs of atrophy - no evident atrophy or tissue thinning seen in the frontal lobe - no evident atrophy or tissue thinning seen in the limbic cortex - mild atrophy of the left occipital lobe and moderate-to-severe atrophy of the right occipital lobe; focal volume loss observed in the following subregions: calcarine cortex (mild atrophy on the left and mild-to-moderate atrophy on the right), inf. occipital gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), sup. occipital gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), cuneus (mild-to-moderate atrophy on the right) and lingual gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) - parietal lobe appears within normal limits without apparent atrophy For the subcortical structures: - hippocampus demonstrates a healthy morphology without signs of atrophy - the putamen shows no notable changes suggestive of atrophy - the pallidum shows no notable changes suggestive of atrophy - no findings suggestive of atrophy are seen in the amygdala - accumbens demonstrates a healthy morphology without signs of atrophy - no findings suggestive of atrophy are seen in the basal forebrain - thalamus maintains a normal appearance with no observable atrophic features - ventral dc demonstrates a healthy morphology without signs of atrophy - no findings suggestive of atrophy are seen in the caudate
CN
FTLD_203561157_02756_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178302
On a T1-weighted brain MRI we observed: For the subcortical structures: - no clear atrophic alterations are visible in the amygdala - no evident atrophy or tissue thinning seen in the thalamus - no clear atrophic alterations are visible in the caudate - the hippocampus shows no notable changes suggestive of atrophy - pallidum demonstrates a healthy morphology without signs of atrophy - no evident atrophy or tissue thinning seen in the ventral dc - no appreciable degenerative or atrophic changes observed in the putamen - the accumbens shows no notable changes suggestive of atrophy - no appreciable degenerative or atrophic changes observed in the basal forebrain For the cerebral cortex: - no evident atrophy or tissue thinning seen in the limbic cortex - the temporal lobe shows no notable changes suggestive of atrophy - frontal lobe maintains a normal appearance with no observable atrophic features - mild atrophy of the right occipital lobe; the left occipital lobe is normal; focal volume loss observed in the following subregions: occipital pole (mild atrophy on the left and normal-to-mild atrophy on the right) and sup. occipital gyrus (normal on the left and mild atrophy on the right) - no evident atrophy or tissue thinning seen in the parietal lobe - insular cortex demonstrates a healthy morphology without signs of atrophy For the ventricles: - 3rd ventricle appears within normal size limits with no apparent enlargement - no observable enlargement of the 4th ventricle - no evident size increase noted in the inf. lateral ventricle - no evident size increase noted in the lateral ventricle - no findings suggestive of enlargement are seen in the external csf
BV
FTLD_203916466_03661_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10451034
On a T1-weighted brain MRI we observed: For the ventricles: - 4th ventricle maintains its expected proportions without signs of enlargement - 3rd ventricle maintains its expected proportions without signs of enlargement - external csf maintains a typical volume without observable enlargement - no clear enlargement or abnormal growth seen in the lateral ventricle - mild enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal For the subcortical structures: - the accumbens shows no notable changes suggestive of atrophy - putamen appears within normal limits without apparent atrophy - mild atrophy of the left thalamus; the right thalamus is normal - mild atrophy of the left hippocampus - mild atrophy of the left ventral dc; the right ventral dc is normal - no appreciable degenerative or atrophic changes observed in the caudate - mild-to-moderate atrophy of the left amygdala and mild atrophy of the right amygdala - mild atrophy of the left pallidum; the right pallidum is normal - no observable atrophic changes in the basal forebrain For the cerebral cortex: - mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left) and posterior insula (mild atrophy on the left and normal on the right) - frontal lobe maintains a normal appearance with no observable atrophic features - no clear atrophic alterations are visible in the parietal lobe - occipital lobe appears preserved, with no observable tissue loss - no clear atrophic alterations are visible in the temporal lobe - no appreciable degenerative or atrophic changes observed in the limbic cortex
PNFA
ADNI_068_S_2248_MR_MPRAGE_br_raw_20130212110530403_99_S181998_I358756
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens - mild atrophy of the right amygdala; normal-to-mild atrophy of the left amygdala - no appreciable degenerative or atrophic changes observed in the putamen - no clear atrophic alterations are visible in the basal forebrain - thalamus demonstrates a healthy morphology without signs of atrophy - no appreciable degenerative or atrophic changes observed in the ventral dc - caudate appears within normal limits without apparent atrophy - the left hippocampus volume is borderline low - no evident atrophy or tissue thinning seen in the pallidum For the cerebral cortex: - no evident atrophy or tissue thinning seen in the occipital lobe - temporal lobe maintains a normal appearance with no observable atrophic features - no observable atrophic changes in the limbic cortex - insular cortex maintains a normal appearance with no observable atrophic features - mild atrophy of the left frontal lobe; normal-to-mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: medial orbital gyrus (mild atrophy both left/right), precentral gyrus (mild atrophy both left/right) and precentral gyrus medial segment (mild-to-moderate atrophy on the left) - mild atrophy of the right parietal lobe; the left parietal lobe is normal; focal volume loss observed in the following subregions: angular gyrus (normal on the left and mild atrophy on the right) For the ventricles: - mild bilateral enlargement of the lateral ventricle - no observable enlargement of the external csf - no findings suggestive of enlargement are seen in the 3rd ventricle - mild-to-moderate bilateral enlargement of the inf. lateral ventricle - mild enlargement of the 4th ventricle
AD
ADNI_037_S_6995_MR_Accelerated_Sagittal_MPRAGE__br_raw_20210922101025650_58_S1064781_I1494601
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild-to-moderate bilateral atrophy of the putamen - thalamus demonstrates a healthy morphology without signs of atrophy - mild bilateral atrophy of the ventral dc - the caudate shows no notable changes suggestive of atrophy - no findings suggestive of atrophy are seen in the amygdala - no clear atrophic alterations are visible in the hippocampus - basal forebrain appears preserved, with no observable tissue loss - mild atrophy of the left accumbens; the right accumbens is normal - mild bilateral atrophy of the pallidum For the cerebral cortex: - the frontal lobe shows no notable changes suggestive of atrophy - the occipital lobe shows no notable changes suggestive of atrophy - parietal lobe demonstrates a healthy morphology without signs of atrophy - insular cortex appears within normal limits without apparent atrophy - no clear atrophic alterations are visible in the temporal lobe - limbic cortex demonstrates a healthy morphology without signs of atrophy For the ventricles: - no findings suggestive of enlargement are seen in the 3rd ventricle - lateral ventricle appears to be of normal dimensions, with no observable increase in size - no findings suggestive of enlargement are seen in the external csf - no evident size increase noted in the inf. lateral ventricle - 4th ventricle maintains its expected proportions without signs of enlargement
CN
FTLD_203571477_02777_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178304
On a T1-weighted brain MRI we observed: For the ventricles: - 3rd ventricle appears within normal size limits with no apparent enlargement - the lateral ventricle shows no notable changes suggestive of enlargement - the 4th ventricle shows no notable changes suggestive of enlargement - severe bilateral enlargement of the inf. lateral ventricle - moderate enlargement of the external csf For the cerebral cortex: - no observable atrophic changes in the parietal lobe - occipital lobe maintains a normal appearance with no observable atrophic features - severe atrophy of the left temporal lobe and moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), inf. temporal gyrus (moderate-to-severe atrophy on the left and mild atrophy on the right), fusiform gyrus (moderate atrophy on the left and mild atrophy on the right), middle temporal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), sup. temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and planum polare (mild atrophy on the left and normal on the right) - mild-to-moderate bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: parahippocampal gyrus (moderate atrophy both left/right), entorhinal area (moderate atrophy on the left and mild-to-moderate atrophy on the right), anterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and middle cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) - mild-to-moderate atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and mild atrophy on the right), posterior insula (mild-to-moderate atrophy on the left and mild atrophy on the right) and frontal operculum (normal-to-mild atrophy on the left and mild atrophy on the right) - no evident atrophy or tissue thinning seen in the frontal lobe For the subcortical structures: - severe bilateral atrophy of the amygdala - no evident atrophy or tissue thinning seen in the basal forebrain - moderate atrophy of the left hippocampus - mild atrophy of the right hippocampus - the pallidum shows no notable changes suggestive of atrophy - no findings suggestive of atrophy are seen in the thalamus - mild-to-moderate atrophy of the left accumbens and mild atrophy of the right accumbens - moderate-to-severe atrophy of the left putamen and mild atrophy of the right putamen - no observable atrophic changes in the ventral dc - mild atrophy of the left caudate; normal-to-mild atrophy of the right caudate
SV
FTLD_203876487_02787_MR_Accelerated_Sagittal_IR-FSPGR_br_raw_202_I10176971
On a T1-weighted brain MRI we observed: For the subcortical structures: - no observable atrophic changes in the thalamus - no clear atrophic alterations are visible in the basal forebrain - no clear atrophic alterations are visible in the amygdala - no findings suggestive of atrophy are seen in the putamen - no observable atrophic changes in the caudate - accumbens appears preserved, with no observable tissue loss - the left hippocampus volume is borderline low - no observable atrophic changes in the ventral dc - no appreciable degenerative or atrophic changes observed in the pallidum For the ventricles: - 4th ventricle appears within normal size limits with no apparent enlargement - mild-to-moderate enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal - external csf maintains its expected proportions without signs of enlargement - mild-to-moderate enlargement of the left lateral ventricle; the right lateral ventricle is normal - the 3rd ventricle shows no notable changes suggestive of enlargement For the cerebral cortex: - no evident atrophy or tissue thinning seen in the parietal lobe - insular cortex appears within normal limits without apparent atrophy - no appreciable degenerative or atrophic changes observed in the temporal lobe - no evident atrophy or tissue thinning seen in the limbic cortex - no observable atrophic changes in the frontal lobe - no evident atrophy or tissue thinning seen in the occipital lobe
CN
FTLD_203337893_03393_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450664
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild atrophy of the right accumbens; normal-to-mild atrophy of the left accumbens - no evident atrophy or tissue thinning seen in the basal forebrain - mild atrophy of the left thalamus; normal-to-mild atrophy of the right thalamus - no appreciable degenerative or atrophic changes observed in the ventral dc - severe atrophy of the left pallidum and moderate-to-severe atrophy of the right pallidum - the putamen shows no notable changes suggestive of atrophy - no observable atrophic changes in the caudate - the left hippocampus volume is borderline low - amygdala demonstrates a healthy morphology without signs of atrophy For the ventricles: - 4th ventricle maintains its expected proportions without signs of enlargement - mild enlargement of the right lateral ventricle; normal-to-mild enlargement of the left lateral ventricle - moderate enlargement of the external csf - mild enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal - mild enlargement of the 3rd ventricle For the cerebral cortex: - mild atrophy of the right insular cortex; the left insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy on the left and mild atrophy on the right), central operculum (mild-to-moderate atrophy on the left and normal on the right) and parietal operculum (mild atrophy on the right) - no clear atrophic alterations are visible in the temporal lobe - occipital lobe appears within normal limits without apparent atrophy - mild bilateral atrophy of the parietal lobe; focal volume loss observed in the following subregions: supramarginal gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right) - mild atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: posterior cingulate gyrus (mild atrophy on the left and normal on the right) - mild atrophy of the left frontal lobe; normal-to-mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: lateral orbital gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), triangular inf. frontal gyrus (mild atrophy both left/right), orbital inf. frontal gyrus (mild atrophy both left/right), gyrus rectus (mild atrophy on the left and normal-to-mild atrophy on the right) and precentral gyrus (mild-to-moderate atrophy on the left and normal on the right)
BV
ADNI_005_S_1341_MR_MPR__GradWarp__B1_Correction__N3__Scaled_Br_20070717180348670_S27673_I60417
On a T1-weighted brain MRI we observed: For the ventricles: - 3rd ventricle maintains a typical volume without observable enlargement - no evident size increase noted in the external csf - no clear enlargement or abnormal growth seen in the lateral ventricle - moderate enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal - mild enlargement of the 4th ventricle For the cerebral cortex: - no appreciable degenerative or atrophic changes observed in the frontal lobe - no observable atrophic changes in the limbic cortex - mild-to-moderate atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: inf. temporal gyrus (mild atrophy both left/right), fusiform gyrus (mild atrophy both left/right), planum polare (normal-to-mild atrophy on the left and mild atrophy on the right) and sup. temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) - no evident atrophy or tissue thinning seen in the occipital lobe - no observable atrophic changes in the parietal lobe - insular cortex maintains a normal appearance with no observable atrophic features For the subcortical structures: - the caudate shows no notable changes suggestive of atrophy - pallidum appears within normal limits without apparent atrophy - mild atrophy of the left hippocampus - the accumbens shows no notable changes suggestive of atrophy - ventral dc appears within normal limits without apparent atrophy - no findings suggestive of atrophy are seen in the basal forebrain - putamen demonstrates a healthy morphology without signs of atrophy - moderate-to-severe atrophy of the left amygdala and mild-to-moderate atrophy of the right amygdala - no appreciable degenerative or atrophic changes observed in the thalamus
AD
FTLD_203088918_01818_MR_Sagittal_MP-Rage_br_raw_20230124205617426_I10178450
On a T1-weighted brain MRI we observed: For the ventricles: - mild bilateral enlargement of the lateral ventricle - no evident size increase noted in the inf. lateral ventricle - external csf maintains a typical volume without observable enlargement - 3rd ventricle maintains its expected proportions without signs of enlargement - no appreciable enlargement noted in the 4th ventricle For the cerebral cortex: - the occipital lobe shows no notable changes suggestive of atrophy - limbic cortex demonstrates a healthy morphology without signs of atrophy - the parietal lobe shows no notable changes suggestive of atrophy - mild atrophy of the left temporal lobe; normal-to-mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: inf. temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), fusiform gyrus (normal on the left and mild atrophy on the right) and planum temporale (mild atrophy on the left) - no appreciable degenerative or atrophic changes observed in the frontal lobe - no findings suggestive of atrophy are seen in the insular cortex For the subcortical structures: - no clear atrophic alterations are visible in the accumbens - amygdala maintains a normal appearance with no observable atrophic features - no appreciable degenerative or atrophic changes observed in the caudate - no evident atrophy or tissue thinning seen in the pallidum - the putamen shows no notable changes suggestive of atrophy - thalamus appears preserved, with no observable tissue loss - basal forebrain maintains a normal appearance with no observable atrophic features - no evident atrophy or tissue thinning seen in the hippocampus - ventral dc maintains a normal appearance with no observable atrophic features
CN
ADNI_021_S_5177_MR_Accelerated_SAG_IR-FSPGR_br_raw_20130517100149157_69_S189689_I372716
On a T1-weighted brain MRI we observed: For the ventricles: - 3rd ventricle appears to be of normal dimensions, with no observable increase in size - the lateral ventricle shows no notable changes suggestive of enlargement - no observable enlargement of the inf. lateral ventricle - mild enlargement of the external csf - no evident size increase noted in the 4th ventricle For the cerebral cortex: - the parietal lobe shows no notable changes suggestive of atrophy - the occipital lobe shows no notable changes suggestive of atrophy - no appreciable degenerative or atrophic changes observed in the temporal lobe - no findings suggestive of atrophy are seen in the frontal lobe - no appreciable degenerative or atrophic changes observed in the limbic cortex - insular cortex appears preserved, with no observable tissue loss For the subcortical structures: - caudate demonstrates a healthy morphology without signs of atrophy - no clear atrophic alterations are visible in the accumbens - no clear atrophic alterations are visible in the pallidum - mild atrophy of the left thalamus; normal-to-mild atrophy of the right thalamus - basal forebrain appears within normal limits without apparent atrophy - mild bilateral atrophy of the putamen - amygdala demonstrates a healthy morphology without signs of atrophy - hippocampus maintains a normal appearance with no observable atrophic features - ventral dc demonstrates a healthy morphology without signs of atrophy
CN
ADNI_033_S_0511_MR_MPR__GradWarp__B1_Correction__N3__Scaled_Br_20080617171837568_S51223_I109915
On a T1-weighted brain MRI we observed: For the subcortical structures: - no evident atrophy or tissue thinning seen in the pallidum - mild bilateral atrophy of the caudate - mild atrophy of the left hippocampus - mild atrophy of the right hippocampus - no evident atrophy or tissue thinning seen in the putamen - no clear atrophic alterations are visible in the basal forebrain - mild atrophy of the right accumbens; normal-to-mild atrophy of the left accumbens - no findings suggestive of atrophy are seen in the ventral dc - thalamus demonstrates a healthy morphology without signs of atrophy - mild atrophy of the left amygdala and moderate atrophy of the right amygdala For the ventricles: - no clear enlargement or abnormal growth seen in the external csf - moderate enlargement of the 3rd ventricle - no observable enlargement of the 4th ventricle - severe enlargement of the left inf. lateral ventricle and moderate-to-severe enlargement of the right inf. lateral ventricle - mild enlargement of the left lateral ventricle and mild-to-moderate enlargement of the right lateral ventricle For the cerebral cortex: - moderate atrophy of the right temporal lobe; normal-to-mild atrophy of the left temporal lobe; focal volume loss observed in the following subregions: middle temporal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right) and inf. temporal gyrus (normal on the left and mild-to-moderate atrophy on the right) - mild atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: posterior cingulate gyrus (mild-to-moderate atrophy on the right) and entorhinal area (mild atrophy on the left and normal on the right) - mild atrophy of the left occipital lobe and mild-to-moderate atrophy of the right occipital lobe; focal volume loss observed in the following subregions: middle occipital gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), sup. occipital gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), occipital fusiform gyrus (normal on the left and mild atrophy on the right) and inf. occipital gyrus (normal on the left and mild atrophy on the right) - no findings suggestive of atrophy are seen in the frontal lobe - insular cortex maintains a normal appearance with no observable atrophic features - mild-to-moderate atrophy of the right parietal lobe; normal-to-mild atrophy of the left parietal lobe; focal volume loss observed in the following subregions: angular gyrus (normal on the left and mild-to-moderate atrophy on the right) and supramarginal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right)
AD
FTLD_203469454_01456_MR_Sagittal_MP-Rage_br_raw_20230206172857063_I10182094
On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild-to-moderate atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild-to-moderate atrophy on the left), entorhinal area (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), middle cingulate gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right) and parahippocampal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) - mild-to-moderate atrophy of the left temporal lobe and moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: inf. temporal gyrus (mild atrophy on the left and moderate atrophy on the right), middle temporal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right) and temporal pole (normal-to-mild atrophy on the left and mild atrophy on the right) - no evident atrophy or tissue thinning seen in the parietal lobe - mild atrophy of the left insular cortex and mild-to-moderate atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and mild-to-moderate atrophy on the right) and central operculum (mild atrophy both left/right) - the occipital lobe shows no notable changes suggestive of atrophy - no clear atrophic alterations are visible in the frontal lobe For the ventricles: - no evident size increase noted in the 4th ventricle - moderate-to-severe bilateral enlargement of the inf. lateral ventricle - external csf maintains a typical volume without observable enlargement - mild-to-moderate enlargement of the 3rd ventricle - mild enlargement of the left lateral ventricle; normal-to-mild enlargement of the right lateral ventricle For the subcortical structures: - no evident atrophy or tissue thinning seen in the caudate - thalamus demonstrates a healthy morphology without signs of atrophy - moderate-to-severe bilateral atrophy of the amygdala - mild bilateral atrophy of the accumbens - no observable atrophic changes in the pallidum - moderate atrophy of the left hippocampus - mild-to-moderate atrophy of the right hippocampus - no evident atrophy or tissue thinning seen in the ventral dc - mild bilateral atrophy of the putamen - no appreciable degenerative or atrophic changes observed in the basal forebrain
SV
FTLD_203197205_03509_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450866
On a T1-weighted brain MRI we observed: For the ventricles: - no findings suggestive of enlargement are seen in the 3rd ventricle - 4th ventricle appears to be of normal dimensions, with no observable increase in size - no findings suggestive of enlargement are seen in the external csf - moderate-to-severe enlargement of the left inf. lateral ventricle; normal-to-mild enlargement of the right inf. lateral ventricle - mild-to-moderate enlargement of the left lateral ventricle and mild enlargement of the right lateral ventricle For the subcortical structures: - caudate maintains a normal appearance with no observable atrophic features - ventral dc appears within normal limits without apparent atrophy - moderate atrophy of the left hippocampus - mild atrophy of the right hippocampus - severe atrophy of the left amygdala and moderate-to-severe atrophy of the right amygdala - thalamus appears preserved, with no observable tissue loss - mild atrophy of the left pallidum; the right pallidum is normal - mild atrophy of the left basal forebrain; the right basal forebrain is normal - mild-to-moderate atrophy of the left putamen and mild atrophy of the right putamen - mild atrophy of the left accumbens; the right accumbens is normal For the cerebral cortex: - moderate atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and mild atrophy on the right), posterior insula (mild-to-moderate atrophy on the left and mild atrophy on the right) and parietal operculum (normal-to-mild atrophy on the left and mild atrophy on the right) - severe atrophy of the left temporal lobe and moderate-to-severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (mild-to-moderate atrophy both left/right), inf. temporal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), middle temporal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), fusiform gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), planum polare (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) and sup. temporal gyrus (mild atrophy on the left) - mild-to-moderate atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: parahippocampal gyrus (moderate atrophy on the left and normal on the right), entorhinal area (mild-to-moderate atrophy on the left and normal on the right), middle cingulate gyrus (mild atrophy on the left) and posterior cingulate gyrus (mild atrophy on the left and normal on the right) - occipital lobe appears within normal limits without apparent atrophy - the parietal lobe shows no notable changes suggestive of atrophy - the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in medial frontal cortex (moderate atrophy on the left), gyrus rectus (mild atrophy on the left and normal-to-mild atrophy on the right), precentral gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and sup. frontal gyrus medial segment (normal on the left and mild atrophy on the right)
SV
ADNI_002_S_1280_MR_MPR__GradWarp__B1_Correction__N3__Scaled_Br_20070713123810416_S26453_I60056
On a T1-weighted brain MRI we observed: For the ventricles: - no clear enlargement or abnormal growth seen in the 3rd ventricle - 4th ventricle appears to be of normal dimensions, with no observable increase in size - no observable enlargement of the lateral ventricle - external csf maintains a typical volume without observable enlargement - inf. lateral ventricle maintains a typical volume without observable enlargement For the subcortical structures: - the ventral dc shows no notable changes suggestive of atrophy - no clear atrophic alterations are visible in the accumbens - amygdala appears preserved, with no observable tissue loss - hippocampus appears preserved, with no observable tissue loss - pallidum demonstrates a healthy morphology without signs of atrophy - no appreciable degenerative or atrophic changes observed in the basal forebrain - the caudate shows no notable changes suggestive of atrophy - putamen appears preserved, with no observable tissue loss - thalamus appears within normal limits without apparent atrophy For the cerebral cortex: - temporal lobe demonstrates a healthy morphology without signs of atrophy - no appreciable degenerative or atrophic changes observed in the insular cortex - no appreciable degenerative or atrophic changes observed in the occipital lobe - the frontal lobe shows no notable changes suggestive of atrophy - mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: parahippocampal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and anterior cingulate gyrus (mild atrophy on the left and normal on the right) - no observable atrophic changes in the parietal lobe
CN
ADNI_141_S_0915_MR_MPRAGE_GRAPPA2_br_raw_20131218095738242_31_S208386_I401994
On a T1-weighted brain MRI we observed: For the subcortical structures: - no observable atrophic changes in the thalamus - accumbens appears preserved, with no observable tissue loss - no clear atrophic alterations are visible in the ventral dc - moderate atrophy of the left amygdala and moderate-to-severe atrophy of the right amygdala - no clear atrophic alterations are visible in the pallidum - no clear atrophic alterations are visible in the putamen - mild-to-moderate atrophy of the left hippocampus - moderate atrophy of the right hippocampus - mild-to-moderate atrophy of the left basal forebrain; the right basal forebrain is normal - no findings suggestive of atrophy are seen in the caudate For the ventricles: - moderate enlargement of the external csf - no findings suggestive of enlargement are seen in the lateral ventricle - mild-to-moderate enlargement of the right inf. lateral ventricle; normal-to-mild enlargement of the left inf. lateral ventricle - no findings suggestive of enlargement are seen in the 4th ventricle - no observable enlargement of the 3rd ventricle For the cerebral cortex: - moderate-to-severe atrophy of the left temporal lobe and severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: inf. temporal gyrus (mild-to-moderate atrophy on the left and moderate-to-severe atrophy on the right), temporal pole (moderate atrophy both left/right), middle temporal gyrus (mild-to-moderate atrophy both left/right) and fusiform gyrus (mild atrophy both left/right) - occipital lobe appears within normal limits without apparent atrophy - limbic cortex appears preserved, with no observable tissue loss - no observable atrophic changes in the insular cortex - the frontal lobe shows no notable changes suggestive of atrophy - moderate-to-severe atrophy of the left parietal lobe and moderate atrophy of the right parietal lobe; focal volume loss observed in the following subregions: angular gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), supramarginal gyrus (mild-to-moderate atrophy both left/right), precuneus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) and postcentral gyrus medial segment (mild atrophy on the left and normal on the right)
AD
ADNI_073_S_4777_MR_MT1__N3m_Br_20161213124755622_S515237_I800044
On a T1-weighted brain MRI we observed: For the subcortical structures: - pallidum demonstrates a healthy morphology without signs of atrophy - mild-to-moderate atrophy of the left hippocampus - mild atrophy of the right hippocampus - no appreciable degenerative or atrophic changes observed in the caudate - accumbens demonstrates a healthy morphology without signs of atrophy - no findings suggestive of atrophy are seen in the ventral dc - the basal forebrain shows no notable changes suggestive of atrophy - no findings suggestive of atrophy are seen in the thalamus - putamen appears within normal limits without apparent atrophy - the amygdala shows no notable changes suggestive of atrophy For the cerebral cortex: - no observable atrophic changes in the parietal lobe - mild atrophy of the left temporal lobe; normal-to-mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: fusiform gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right) and transverse temporal gyrus (mild atrophy both left/right) - no clear atrophic alterations are visible in the insular cortex - the occipital lobe shows no notable changes suggestive of atrophy - no appreciable degenerative or atrophic changes observed in the limbic cortex - no evident atrophy or tissue thinning seen in the frontal lobe For the ventricles: - no clear enlargement or abnormal growth seen in the 4th ventricle - mild-to-moderate enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle - no findings suggestive of enlargement are seen in the lateral ventricle - external csf appears within normal size limits with no apparent enlargement - no observable enlargement of the 3rd ventricle
AD
FTLD_203380788_01888_MR_Sagittal_MP-Rage_br_raw_20230206175423133_I10182285
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild atrophy of the right amygdala; the left amygdala is normal - mild atrophy of the left caudate and moderate atrophy of the right caudate - basal forebrain appears preserved, with no observable tissue loss - mild-to-moderate atrophy of the right pallidum; normal-to-mild atrophy of the left pallidum - the left hippocampus volume is borderline low - mild-to-moderate atrophy of the left putamen and moderate-to-severe atrophy of the right putamen - no clear atrophic alterations are visible in the accumbens - mild atrophy of the right thalamus; the left thalamus is normal - mild atrophy of the right ventral dc; the left ventral dc is normal For the cerebral cortex: - the parietal lobe shows no notable changes suggestive of atrophy - occipital lobe appears preserved, with no observable tissue loss - mild atrophy of the right temporal lobe; the left temporal lobe is normal; focal volume loss observed in the following subregions: planum temporale (normal on the left and mild atrophy on the right) - mild atrophy of the right insular cortex; normal-to-mild atrophy of the left insular cortex; focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and moderate atrophy on the right) and frontal operculum (mild atrophy on the left and normal on the right) - mild-to-moderate atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (normal on the left and mild atrophy on the right) and entorhinal area (mild atrophy on the right) - mild-to-moderate atrophy of the left frontal lobe and severe atrophy of the right frontal lobe; focal volume loss observed in the following subregions: triangular inf. frontal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), middle frontal gyrus (normal-to-mild atrophy on the left and moderate atrophy on the right), opercular inf. frontal gyrus (mild atrophy both left/right), orbital inf. frontal gyrus (mild atrophy both left/right), posterior orbital gyrus (mild-to-moderate atrophy on the right), precentral gyrus (normal on the left and mild-to-moderate atrophy on the right), sup. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), frontal pole (normal on the left and mild atrophy on the right), gyrus rectus (mild atrophy on the right), lateral orbital gyrus (mild atrophy on the left and normal on the right) and precentral gyrus medial segment (mild atrophy on the left and normal on the right) For the ventricles: - mild enlargement of the right lateral ventricle; the left lateral ventricle is normal - no appreciable enlargement noted in the 4th ventricle - mild enlargement of the 3rd ventricle - moderate enlargement of the external csf - severe enlargement of the right inf. lateral ventricle; the left inf. lateral ventricle is normal
PNFA
FTLD_203916466_03661_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10451034
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild-to-moderate atrophy of the left amygdala and mild atrophy of the right amygdala - basal forebrain appears within normal limits without apparent atrophy - no evident atrophy or tissue thinning seen in the putamen - mild atrophy of the left ventral dc; the right ventral dc is normal - mild atrophy of the left thalamus; the right thalamus is normal - caudate demonstrates a healthy morphology without signs of atrophy - accumbens maintains a normal appearance with no observable atrophic features - mild atrophy of the left pallidum; the right pallidum is normal - mild atrophy of the left hippocampus For the ventricles: - external csf appears within normal size limits with no apparent enlargement - no evident size increase noted in the 3rd ventricle - no observable enlargement of the lateral ventricle - mild enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal - no appreciable enlargement noted in the 4th ventricle For the cerebral cortex: - no appreciable degenerative or atrophic changes observed in the limbic cortex - no appreciable degenerative or atrophic changes observed in the temporal lobe - no findings suggestive of atrophy are seen in the frontal lobe - occipital lobe demonstrates a healthy morphology without signs of atrophy - mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left) and posterior insula (mild atrophy on the left and normal on the right) - parietal lobe maintains a normal appearance with no observable atrophic features
PNFA
FTLD_203489181_03188_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10176905
On a T1-weighted brain MRI we observed: For the ventricles: - mild-to-moderate bilateral enlargement of the lateral ventricle - no appreciable enlargement noted in the external csf - mild enlargement of the 3rd ventricle - mild-to-moderate enlargement of the right inf. lateral ventricle; the left inf. lateral ventricle is normal - mild enlargement of the 4th ventricle For the subcortical structures: - no clear atrophic alterations are visible in the pallidum - no observable atrophic changes in the ventral dc - no evident atrophy or tissue thinning seen in the basal forebrain - mild atrophy of the left accumbens; the right accumbens is normal - caudate appears preserved, with no observable tissue loss - the left hippocampus volume is borderline low - putamen appears within normal limits without apparent atrophy - thalamus maintains a normal appearance with no observable atrophic features - amygdala appears within normal limits without apparent atrophy For the cerebral cortex: - occipital lobe maintains a normal appearance with no observable atrophic features - mild-to-moderate bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: anterior insula (mild atrophy both left/right), central operculum (normal-to-mild atrophy on the left and mild atrophy on the right), posterior insula (normal on the left and mild atrophy on the right), frontal operculum (mild atrophy on the left and normal on the right) and parietal operculum (mild atrophy on the left and normal on the right) - no findings suggestive of atrophy are seen in the parietal lobe - limbic cortex appears preserved, with no observable tissue loss - the frontal lobe shows no notable changes suggestive of atrophy - no appreciable degenerative or atrophic changes observed in the temporal lobe
BV
FTLD_203447418_03814_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10451166
On a T1-weighted brain MRI we observed: For the subcortical structures: - basal forebrain appears preserved, with no observable tissue loss - mild atrophy of the left putamen; the right putamen is normal - mild atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens - severe atrophy of the left amygdala and mild-to-moderate atrophy of the right amygdala - moderate atrophy of the left hippocampus - mild atrophy of the right hippocampus - caudate appears preserved, with no observable tissue loss - pallidum maintains a normal appearance with no observable atrophic features - no evident atrophy or tissue thinning seen in the thalamus - no observable atrophic changes in the ventral dc For the ventricles: - mild bilateral enlargement of the lateral ventricle - severe enlargement of the left inf. lateral ventricle and moderate-to-severe enlargement of the right inf. lateral ventricle - no appreciable enlargement noted in the 3rd ventricle - external csf maintains its expected proportions without signs of enlargement - the 4th ventricle shows no notable changes suggestive of enlargement For the cerebral cortex: - severe atrophy of the left temporal lobe and moderate-to-severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), middle temporal gyrus (moderate-to-severe atrophy on the left and mild atrophy on the right), inf. temporal gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), fusiform gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), planum temporale (mild atrophy on the left and mild-to-moderate atrophy on the right) and sup. temporal gyrus (mild atrophy on the left and normal on the right) - mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: parietal operculum (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), posterior insula (mild atrophy on the left) and central operculum (mild atrophy on the left and normal on the right) - limbic cortex appears within normal limits without apparent atrophy - the parietal lobe shows no notable changes suggestive of atrophy - no observable atrophic changes in the frontal lobe - occipital lobe maintains a normal appearance with no observable atrophic features
SV
ADNI_009_S_5037_MR_MPRAGE_GRAPPA2_br_raw_20130115124943538_34_S180196_I355084
On a T1-weighted brain MRI we observed: For the subcortical structures: - moderate atrophy of the left hippocampus - moderate atrophy of the right hippocampus - severe atrophy of the left amygdala and moderate-to-severe atrophy of the right amygdala - moderate-to-severe atrophy of the left putamen and moderate atrophy of the right putamen - moderate atrophy of the left thalamus and mild-to-moderate atrophy of the right thalamus - the basal forebrain shows no notable changes suggestive of atrophy - moderate bilateral atrophy of the caudate - moderate-to-severe bilateral atrophy of the pallidum - mild atrophy of the left ventral dc and mild-to-moderate atrophy of the right ventral dc - moderate atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens For the ventricles: - 4th ventricle maintains its expected proportions without signs of enlargement - severe enlargement of the left inf. lateral ventricle and mild-to-moderate enlargement of the right inf. lateral ventricle - mild enlargement of the 3rd ventricle - moderate-to-severe enlargement of the left lateral ventricle and severe enlargement of the right lateral ventricle - mild-to-moderate enlargement of the external csf For the cerebral cortex: - frontal lobe appears preserved, with no observable tissue loss - mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and normal on the right) - mild atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: inf. temporal gyrus (mild-to-moderate atrophy on the left and normal on the right) and middle temporal gyrus (mild atrophy on the left and normal on the right) - occipital lobe appears preserved, with no observable tissue loss - no clear atrophic alterations are visible in the parietal lobe - mild-to-moderate atrophy of the left limbic cortex; normal-to-mild atrophy of the right limbic cortex; focal volume loss observed in the following subregions: parahippocampal gyrus (moderate atrophy on the left and mild atrophy on the right), entorhinal area (mild atrophy on the left and normal-to-mild atrophy on the right), anterior cingulate gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and middle cingulate gyrus (mild atrophy on the left)
AD
ADNI_035_S_0341_MR_MPR__GradWarp__B1_Correction__N3__Scaled_Br_20070319175003745_S12952_I45213
On a T1-weighted brain MRI we observed: For the subcortical structures: - no evident atrophy or tissue thinning seen in the putamen - no appreciable degenerative or atrophic changes observed in the ventral dc - moderate bilateral atrophy of the amygdala - moderate atrophy of the left hippocampus - moderate-to-severe atrophy of the right hippocampus - no appreciable degenerative or atrophic changes observed in the thalamus - no findings suggestive of atrophy are seen in the accumbens - no findings suggestive of atrophy are seen in the caudate - no observable atrophic changes in the pallidum - the basal forebrain shows no notable changes suggestive of atrophy For the cerebral cortex: - temporal lobe appears preserved, with no observable tissue loss - occipital lobe demonstrates a healthy morphology without signs of atrophy - frontal lobe maintains a normal appearance with no observable atrophic features - insular cortex appears preserved, with no observable tissue loss - mild bilateral atrophy of the parietal lobe; focal volume loss observed in the following subregions: sup. parietal lobule (mild-to-moderate atrophy on the left and mild atrophy on the right) and precuneus (mild atrophy on the left and normal on the right) - no evident atrophy or tissue thinning seen in the limbic cortex For the ventricles: - moderate bilateral enlargement of the lateral ventricle - mild enlargement of the 4th ventricle - external csf maintains a typical volume without observable enlargement - mild enlargement of the 3rd ventricle - moderate-to-severe bilateral enlargement of the inf. lateral ventricle
AD
FTLD_203792827_02729_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10176876
On a T1-weighted brain MRI we observed: For the subcortical structures: - severe atrophy of the left caudate and moderate atrophy of the right caudate - moderate atrophy of the left pallidum and mild atrophy of the right pallidum - mild atrophy of the left thalamus; the right thalamus is normal - moderate-to-severe atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens - moderate-to-severe atrophy of the left amygdala and mild-to-moderate atrophy of the right amygdala - severe atrophy of the left putamen and mild-to-moderate atrophy of the right putamen - basal forebrain demonstrates a healthy morphology without signs of atrophy - mild atrophy of the left hippocampus - mild atrophy of the right hippocampus - mild bilateral atrophy of the ventral dc For the ventricles: - moderate-to-severe enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle - no findings suggestive of enlargement are seen in the 4th ventricle - moderate-to-severe enlargement of the left lateral ventricle and severe enlargement of the right lateral ventricle - no findings suggestive of enlargement are seen in the 3rd ventricle - moderate-to-severe enlargement of the external csf For the cerebral cortex: - moderate atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy on the left and mild atrophy on the right), middle temporal gyrus (moderate-to-severe atrophy on the left) and planum polare (normal-to-mild atrophy on the left and mild atrophy on the right) - moderate-to-severe atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (severe atrophy on the left and normal-to-mild atrophy on the right), frontal operculum (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), central operculum (mild atrophy both left/right) and parietal operculum (mild atrophy on the left) - severe atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: triangular inf. frontal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), opercular inf. frontal gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), middle frontal gyrus (moderate atrophy on the left), sup. frontal gyrus (moderate atrophy on the left), lateral orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), orbital inf. frontal gyrus (mild atrophy on the left), posterior orbital gyrus (mild atrophy on the left and normal on the right), precentral gyrus (mild atrophy on the left) and sup. frontal gyrus medial segment (mild atrophy on the left) - mild-to-moderate atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (moderate atrophy on the left and mild atrophy on the right) and parahippocampal gyrus (mild atrophy on the left) - the occipital lobe shows no notable changes suggestive of atrophy - parietal lobe appears within normal limits without apparent atrophy
BV
FTLD_203380788_01888_MR_Sagittal_MP-Rage_br_raw_20230206175423133_I10182285
On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild-to-moderate atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (normal on the left and mild atrophy on the right) and entorhinal area (mild atrophy on the right) - mild atrophy of the right insular cortex; normal-to-mild atrophy of the left insular cortex; focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and moderate atrophy on the right) and frontal operculum (mild atrophy on the left and normal on the right) - parietal lobe appears preserved, with no observable tissue loss - occipital lobe appears preserved, with no observable tissue loss - mild-to-moderate atrophy of the left frontal lobe and severe atrophy of the right frontal lobe; focal volume loss observed in the following subregions: triangular inf. frontal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), middle frontal gyrus (normal-to-mild atrophy on the left and moderate atrophy on the right), opercular inf. frontal gyrus (mild atrophy both left/right), orbital inf. frontal gyrus (mild atrophy both left/right), posterior orbital gyrus (mild-to-moderate atrophy on the right), precentral gyrus (normal on the left and mild-to-moderate atrophy on the right), sup. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), frontal pole (normal on the left and mild atrophy on the right), gyrus rectus (mild atrophy on the right), lateral orbital gyrus (mild atrophy on the left and normal on the right) and precentral gyrus medial segment (mild atrophy on the left and normal on the right) - mild atrophy of the right temporal lobe; the left temporal lobe is normal; focal volume loss observed in the following subregions: planum temporale (normal on the left and mild atrophy on the right) For the subcortical structures: - mild atrophy of the right thalamus; the left thalamus is normal - no observable atrophic changes in the accumbens - mild-to-moderate atrophy of the right pallidum; normal-to-mild atrophy of the left pallidum - mild atrophy of the right amygdala; the left amygdala is normal - mild-to-moderate atrophy of the left putamen and moderate-to-severe atrophy of the right putamen - mild atrophy of the left caudate and moderate atrophy of the right caudate - basal forebrain demonstrates a healthy morphology without signs of atrophy - the left hippocampus volume is borderline low - mild atrophy of the right ventral dc; the left ventral dc is normal For the ventricles: - moderate enlargement of the external csf - mild enlargement of the right lateral ventricle; the left lateral ventricle is normal - severe enlargement of the right inf. lateral ventricle; the left inf. lateral ventricle is normal - mild enlargement of the 3rd ventricle - no appreciable enlargement noted in the 4th ventricle
PNFA
FTLD_203519612_03211_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178291
On a T1-weighted brain MRI we observed: For the ventricles: - the 4th ventricle shows no notable changes suggestive of enlargement - mild-to-moderate enlargement of the 3rd ventricle - severe bilateral enlargement of the inf. lateral ventricle - moderate-to-severe enlargement of the external csf - mild bilateral enlargement of the lateral ventricle For the cerebral cortex: - no findings suggestive of atrophy are seen in the occipital lobe - severe atrophy of the left temporal lobe and moderate-to-severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy on the left and moderate atrophy on the right), fusiform gyrus (moderate atrophy both left/right), inf. temporal gyrus (moderate-to-severe atrophy on the left and normal-to-mild atrophy on the right), middle temporal gyrus (mild-to-moderate atrophy both left/right), sup. temporal gyrus (moderate atrophy on the left and mild atrophy on the right) and planum polare (mild-to-moderate atrophy on the left and normal on the right) - mild atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: gyrus rectus (normal-to-mild atrophy on the left and mild atrophy on the right), middle frontal gyrus (mild atrophy on the left), medial orbital gyrus (mild atrophy on the left), sup. frontal gyrus (normal on the left and mild atrophy on the right), lateral orbital gyrus (mild atrophy on the right) and precentral gyrus medial segment (mild atrophy on the left) - no evident atrophy or tissue thinning seen in the parietal lobe - mild atrophy of the left limbic cortex and mild-to-moderate atrophy of the right limbic cortex; focal volume loss observed in the following subregions: parahippocampal gyrus (moderate atrophy on the left and mild atrophy on the right), entorhinal area (mild-to-moderate atrophy on the left and mild atrophy on the right) and anterior cingulate gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) - mild bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and mild-to-moderate atrophy on the right) and posterior insula (mild-to-moderate atrophy both left/right) For the subcortical structures: - no appreciable degenerative or atrophic changes observed in the basal forebrain - mild-to-moderate atrophy of the left hippocampus - mild-to-moderate atrophy of the right hippocampus - mild-to-moderate atrophy of the left thalamus and mild atrophy of the right thalamus - moderate atrophy of the left accumbens and mild atrophy of the right accumbens - moderate atrophy of the left caudate and mild atrophy of the right caudate - severe bilateral atrophy of the amygdala - moderate-to-severe atrophy of the left putamen and mild-to-moderate atrophy of the right putamen - moderate-to-severe atrophy of the left pallidum and mild-to-moderate atrophy of the right pallidum - no evident atrophy or tissue thinning seen in the ventral dc
SV
ADNI_130_S_4971_MR_MPRAGE_br_raw_20121025110023272_8_S172180_I342338
On a T1-weighted brain MRI we observed: For the ventricles: - moderate enlargement of the 3rd ventricle - mild bilateral enlargement of the lateral ventricle - severe bilateral enlargement of the inf. lateral ventricle - external csf maintains its expected proportions without signs of enlargement - 4th ventricle appears to be of normal dimensions, with no observable increase in size For the subcortical structures: - mild atrophy of the left caudate and mild-to-moderate atrophy of the right caudate - mild bilateral atrophy of the accumbens - mild-to-moderate bilateral atrophy of the putamen - moderate atrophy of the left amygdala and mild-to-moderate atrophy of the right amygdala - basal forebrain maintains a normal appearance with no observable atrophic features - mild-to-moderate atrophy of the left thalamus and moderate atrophy of the right thalamus - mild bilateral atrophy of the pallidum - mild-to-moderate atrophy of the left hippocampus - mild atrophy of the right hippocampus - no findings suggestive of atrophy are seen in the ventral dc For the cerebral cortex: - mild bilateral atrophy of the parietal lobe; focal volume loss observed in the following subregions: angular gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), postcentral gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and supramarginal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) - occipital lobe maintains a normal appearance with no observable atrophic features - mild atrophy of the left limbic cortex; normal-to-mild atrophy of the right limbic cortex; focal volume loss observed in the following subregions: middle cingulate gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right) - no evident atrophy or tissue thinning seen in the temporal lobe - mild-to-moderate atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and mild-to-moderate atrophy on the right), posterior insula (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) and central operculum (mild atrophy on the left and normal-to-mild atrophy on the right) - mild atrophy of the left frontal lobe; normal-to-mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: subcallosal area (mild atrophy both left/right), orbital inf. frontal gyrus (mild-to-moderate atrophy on the left and normal on the right), posterior orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and sup. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right)
AD
ADNI_036_S_4820_MR_MPRAGE_br_raw_20120718104734388_6_S157909_I316737
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no clear atrophic alterations are visible in the insular cortex - temporal lobe appears within normal limits without apparent atrophy - parietal lobe appears within normal limits without apparent atrophy - frontal lobe appears preserved, with no observable tissue loss - mild atrophy of the left occipital lobe and moderate atrophy of the right occipital lobe; focal volume loss observed in the following subregions: lingual gyrus (mild atrophy both left/right), inf. occipital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), cuneus (mild atrophy on the left and normal on the right), middle occipital gyrus (normal on the left and mild atrophy on the right) and occipital fusiform gyrus (normal on the left and mild atrophy on the right) - no evident atrophy or tissue thinning seen in the limbic cortex For the subcortical structures: - no observable atrophic changes in the ventral dc - no appreciable degenerative or atrophic changes observed in the putamen - mild bilateral atrophy of the amygdala - mild atrophy of the left hippocampus - mild bilateral atrophy of the accumbens - no observable atrophic changes in the basal forebrain - no findings suggestive of atrophy are seen in the thalamus - no findings suggestive of atrophy are seen in the pallidum - caudate demonstrates a healthy morphology without signs of atrophy For the ventricles: - 3rd ventricle maintains a typical volume without observable enlargement - no findings suggestive of enlargement are seen in the external csf - the inf. lateral ventricle shows no notable changes suggestive of enlargement - mild enlargement of the 4th ventricle - no evident size increase noted in the lateral ventricle
AD
FTLD_203932722_03223_MR_Accelerated_Sagittal_MPRAGE_br_raw_20241_I11047338
On a T1-weighted brain MRI we observed: For the subcortical structures: - severe bilateral atrophy of the putamen - moderate bilateral atrophy of the pallidum - no findings suggestive of atrophy are seen in the basal forebrain - mild-to-moderate atrophy of the left accumbens and moderate-to-severe atrophy of the right accumbens - mild bilateral atrophy of the amygdala - moderate atrophy of the left caudate and moderate-to-severe atrophy of the right caudate - mild atrophy of the left hippocampus - mild atrophy of the right hippocampus - moderate-to-severe atrophy of the left thalamus and moderate atrophy of the right thalamus - mild bilateral atrophy of the ventral dc For the cerebral cortex: - mild atrophy of the left frontal lobe; normal-to-mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: frontal pole (mild atrophy on the left and mild-to-moderate atrophy on the right), gyrus rectus (mild atrophy on the left and normal on the right), anterior orbital gyrus (mild atrophy on the right) and medial orbital gyrus (mild atrophy on the left) - no appreciable degenerative or atrophic changes observed in the insular cortex - no findings suggestive of atrophy are seen in the occipital lobe - mild-to-moderate atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: middle temporal gyrus (mild-to-moderate atrophy both left/right), sup. temporal gyrus (mild atrophy both left/right), planum temporale (mild atrophy on the left and normal-to-mild atrophy on the right) and temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right) - no clear atrophic alterations are visible in the limbic cortex - the parietal lobe shows no notable changes suggestive of atrophy For the ventricles: - no clear enlargement or abnormal growth seen in the 4th ventricle - moderate-to-severe enlargement of the external csf - 3rd ventricle maintains its expected proportions without signs of enlargement - mild bilateral enlargement of the inf. lateral ventricle - mild enlargement of the left lateral ventricle and mild-to-moderate enlargement of the right lateral ventricle
BV
ADNI_041_S_0125_MR_MPR__GradWarp__B1_Correction__N3__Scaled_Br_20070109234918469_S10883_I35671
On a T1-weighted brain MRI we observed: For the subcortical structures: - no clear atrophic alterations are visible in the accumbens - mild-to-moderate atrophy of the left putamen and mild atrophy of the right putamen - no findings suggestive of atrophy are seen in the amygdala - no evident atrophy or tissue thinning seen in the ventral dc - no findings suggestive of atrophy are seen in the basal forebrain - no appreciable degenerative or atrophic changes observed in the caudate - mild bilateral atrophy of the pallidum - no clear atrophic alterations are visible in the hippocampus - no clear atrophic alterations are visible in the thalamus For the ventricles: - mild enlargement of the left lateral ventricle; normal-to-mild enlargement of the right lateral ventricle - the external csf shows no notable changes suggestive of enlargement - no evident size increase noted in the 4th ventricle - no appreciable enlargement noted in the 3rd ventricle - no findings suggestive of enlargement are seen in the inf. lateral ventricle For the cerebral cortex: - no appreciable degenerative or atrophic changes observed in the insular cortex - temporal lobe maintains a normal appearance with no observable atrophic features - no clear atrophic alterations are visible in the occipital lobe - no evident atrophy or tissue thinning seen in the limbic cortex - no appreciable degenerative or atrophic changes observed in the parietal lobe - no observable atrophic changes in the frontal lobe
CN
ADNI_021_S_5236_MR_Sag_IR-FSPGR_br_raw_20130627162135843_162_S193604_I378470
On a T1-weighted brain MRI we observed: For the ventricles: - 4th ventricle appears to be of normal dimensions, with no observable increase in size - 3rd ventricle appears within normal size limits with no apparent enlargement - no observable enlargement of the inf. lateral ventricle - the lateral ventricle shows no notable changes suggestive of enlargement - the external csf shows no notable changes suggestive of enlargement For the cerebral cortex: - no findings suggestive of atrophy are seen in the occipital lobe - frontal lobe maintains a normal appearance with no observable atrophic features - no findings suggestive of atrophy are seen in the parietal lobe - the temporal lobe shows no notable changes suggestive of atrophy - no appreciable degenerative or atrophic changes observed in the limbic cortex - no observable atrophic changes in the insular cortex For the subcortical structures: - hippocampus appears preserved, with no observable tissue loss - no evident atrophy or tissue thinning seen in the caudate - no observable atrophic changes in the thalamus - no evident atrophy or tissue thinning seen in the pallidum - ventral dc appears within normal limits without apparent atrophy - putamen demonstrates a healthy morphology without signs of atrophy - no findings suggestive of atrophy are seen in the accumbens - mild atrophy of the right basal forebrain; the left basal forebrain is normal - no findings suggestive of atrophy are seen in the amygdala
CN
ADNI_099_S_0492_MR_MPR__GradWarp__B1_Correction__N3__Scaled_Br_20070209170021020_S14944_I38770
On a T1-weighted brain MRI we observed: For the ventricles: - lateral ventricle maintains a typical volume without observable enlargement - mild enlargement of the 4th ventricle - severe enlargement of the left inf. lateral ventricle and mild-to-moderate enlargement of the right inf. lateral ventricle - no appreciable enlargement noted in the external csf - no appreciable enlargement noted in the 3rd ventricle For the subcortical structures: - accumbens maintains a normal appearance with no observable atrophic features - no clear atrophic alterations are visible in the basal forebrain - ventral dc maintains a normal appearance with no observable atrophic features - putamen demonstrates a healthy morphology without signs of atrophy - caudate maintains a normal appearance with no observable atrophic features - no appreciable degenerative or atrophic changes observed in the pallidum - mild bilateral atrophy of the amygdala - no evident atrophy or tissue thinning seen in the thalamus - mild atrophy of the left hippocampus - the left hippocampus volume is borderline low For the cerebral cortex: - insular cortex appears within normal limits without apparent atrophy; focal volume loss observed in the following subregions: central operculum (mild atrophy both left/right) - no evident atrophy or tissue thinning seen in the occipital lobe - frontal lobe maintains a normal appearance with no observable atrophic features - moderate atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: fusiform gyrus (mild atrophy both left/right), middle temporal gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), planum polare (mild atrophy on the left and normal-to-mild atrophy on the right), temporal pole (normal-to-mild atrophy on the left and mild atrophy on the right) and inf. temporal gyrus (mild atrophy on the left) - mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (mild atrophy on the left and normal-to-mild atrophy on the right) and posterior cingulate gyrus (mild atrophy on the left and normal on the right) - parietal lobe appears within normal limits without apparent atrophy
AD
FTLD_203807239_02930_MR_Accelerated_Sagittal_IR-FSPGR_br_raw_202_I10176979
On a T1-weighted brain MRI we observed: For the subcortical structures: - no findings suggestive of atrophy are seen in the ventral dc - mild atrophy of the right accumbens; normal-to-mild atrophy of the left accumbens - mild-to-moderate atrophy of the left pallidum; normal-to-mild atrophy of the right pallidum - amygdala appears within normal limits without apparent atrophy - basal forebrain maintains a normal appearance with no observable atrophic features - mild-to-moderate atrophy of the left caudate and mild atrophy of the right caudate - no findings suggestive of atrophy are seen in the thalamus - the left hippocampus volume is borderline low - moderate atrophy of the left putamen; normal-to-mild atrophy of the right putamen For the ventricles: - no clear enlargement or abnormal growth seen in the 4th ventricle - mild-to-moderate bilateral enlargement of the inf. lateral ventricle - mild bilateral enlargement of the lateral ventricle - mild-to-moderate enlargement of the external csf - no observable enlargement of the 3rd ventricle For the cerebral cortex: - insular cortex appears preserved, with no observable tissue loss - no appreciable degenerative or atrophic changes observed in the limbic cortex - no appreciable degenerative or atrophic changes observed in the parietal lobe - no clear atrophic alterations are visible in the temporal lobe - no observable atrophic changes in the occipital lobe - moderate-to-severe atrophy of the left frontal lobe and mild-to-moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), frontal pole (mild atrophy both left/right), orbital inf. frontal gyrus (mild atrophy both left/right), sup. frontal gyrus (mild atrophy both left/right), opercular inf. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), lateral orbital gyrus (normal on the left and mild-to-moderate atrophy on the right), anterior orbital gyrus (normal on the left and mild atrophy on the right), precentral gyrus (mild atrophy on the left and normal on the right) and supplementary motor cortex (mild atrophy on the left)
PNFA
ADNI_009_S_5224_MR_MPRAGE_br_raw_20130717152112089_161_S195460_I381184
On a T1-weighted brain MRI we observed: For the ventricles: - no evident size increase noted in the 4th ventricle - mild enlargement of the right lateral ventricle; normal-to-mild enlargement of the left lateral ventricle - mild enlargement of the 3rd ventricle - mild enlargement of the external csf - mild enlargement of the left inf. lateral ventricle and moderate-to-severe enlargement of the right inf. lateral ventricle For the cerebral cortex: - no evident atrophy or tissue thinning seen in the parietal lobe - no findings suggestive of atrophy are seen in the occipital lobe - mild bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: entorhinal area (mild-to-moderate atrophy both left/right) and parahippocampal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right) - frontal lobe appears within normal limits without apparent atrophy - mild-to-moderate atrophy of the right insular cortex; normal-to-mild atrophy of the left insular cortex; focal volume loss observed in the following subregions: posterior insula (normal-to-mild atrophy on the left and mild atrophy on the right), frontal operculum (mild atrophy on the left and normal-to-mild atrophy on the right) and central operculum (normal on the left and mild atrophy on the right) - mild-to-moderate atrophy of the right temporal lobe; normal-to-mild atrophy of the left temporal lobe; focal volume loss observed in the following subregions: temporal pole (mild-to-moderate atrophy on the left and moderate atrophy on the right), middle temporal gyrus (mild atrophy both left/right), inf. temporal gyrus (mild atrophy on the right) and transverse temporal gyrus (mild atrophy on the left) For the subcortical structures: - severe bilateral atrophy of the amygdala - mild atrophy of the left hippocampus - mild-to-moderate atrophy of the right hippocampus - putamen demonstrates a healthy morphology without signs of atrophy - no clear atrophic alterations are visible in the caudate - basal forebrain demonstrates a healthy morphology without signs of atrophy - no clear atrophic alterations are visible in the pallidum - mild bilateral atrophy of the accumbens - no clear atrophic alterations are visible in the thalamus - mild atrophy of the right ventral dc; normal-to-mild atrophy of the left ventral dc
AD
FTLD_203231766_02663_MR_Accelerated_Sagittal_MPRAGE_Repeat_br_raw_I10178175
On a T1-weighted brain MRI we observed: For the subcortical structures: - moderate-to-severe atrophy of the left amygdala and severe atrophy of the right amygdala - no evident atrophy or tissue thinning seen in the ventral dc - pallidum demonstrates a healthy morphology without signs of atrophy - the basal forebrain shows no notable changes suggestive of atrophy - mild atrophy of the right caudate; the left caudate is normal - mild-to-moderate atrophy of the right hippocampus - thalamus maintains a normal appearance with no observable atrophic features - mild atrophy of the right putamen; normal-to-mild atrophy of the left putamen - mild atrophy of the left accumbens and moderate atrophy of the right accumbens For the cerebral cortex: - mild-to-moderate atrophy of the right insular cortex; the left insular cortex is normal; focal volume loss observed in the following subregions: posterior insula (mild-to-moderate atrophy on the left and moderate-to-severe atrophy on the right), anterior insula (normal on the left and moderate atrophy on the right) and frontal operculum (normal-to-mild atrophy on the left and mild atrophy on the right) - moderate atrophy of the left temporal lobe and severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: middle temporal gyrus (mild atrophy on the left and moderate-to-severe atrophy on the right), temporal pole (mild atrophy on the left and moderate-to-severe atrophy on the right), fusiform gyrus (mild-to-moderate atrophy both left/right), inf. temporal gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right) and sup. temporal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) - mild atrophy of the right frontal lobe; the left frontal lobe is normal; focal volume loss observed in the following subregions: subcallosal area (mild atrophy on the left and mild-to-moderate atrophy on the right), frontal pole (mild atrophy both left/right), gyrus rectus (mild atrophy both left/right) and middle frontal gyrus (normal on the left and mild atrophy on the right) - no clear atrophic alterations are visible in the occipital lobe - mild-to-moderate bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: parahippocampal gyrus (mild-to-moderate atrophy on the left and moderate atrophy on the right), entorhinal area (mild atrophy on the left and moderate atrophy on the right), middle cingulate gyrus (mild atrophy both left/right) and anterior cingulate gyrus (mild atrophy on the left and normal on the right) - parietal lobe appears within normal limits without apparent atrophy For the ventricles: - moderate enlargement of the right inf. lateral ventricle; the left inf. lateral ventricle is normal - moderate enlargement of the external csf - 3rd ventricle appears to be of normal dimensions, with no observable increase in size - no evident size increase noted in the 4th ventricle - lateral ventricle maintains a typical volume without observable enlargement
SV
ADNI_029_S_0836_MR_MPR__GradWarp__B1_Correction__N3__Scaled_Br_20070806122937449_S18151_I65013
On a T1-weighted brain MRI we observed: For the ventricles: - mild enlargement of the left lateral ventricle; normal-to-mild enlargement of the right lateral ventricle - no observable enlargement of the 3rd ventricle - external csf maintains a typical volume without observable enlargement - no clear enlargement or abnormal growth seen in the 4th ventricle - no findings suggestive of enlargement are seen in the inf. lateral ventricle For the cerebral cortex: - no appreciable degenerative or atrophic changes observed in the temporal lobe - insular cortex appears preserved, with no observable tissue loss - no observable atrophic changes in the limbic cortex - parietal lobe appears preserved, with no observable tissue loss - occipital lobe appears preserved, with no observable tissue loss - frontal lobe appears preserved, with no observable tissue loss For the subcortical structures: - moderate atrophy of the left hippocampus - mild atrophy of the right hippocampus - mild atrophy of the right basal forebrain; the left basal forebrain is normal - mild atrophy of the left ventral dc; normal-to-mild atrophy of the right ventral dc - no clear atrophic alterations are visible in the pallidum - no findings suggestive of atrophy are seen in the caudate - no clear atrophic alterations are visible in the thalamus - the putamen shows no notable changes suggestive of atrophy - accumbens maintains a normal appearance with no observable atrophic features - no clear atrophic alterations are visible in the amygdala
AD
ADNI_073_S_0311_MR_MPR__GradWarp__B1_Correction__N3__Scaled_Br_20070213203125567_S15069_I39868
On a T1-weighted brain MRI we observed: For the ventricles: - no observable enlargement of the lateral ventricle - the 4th ventricle shows no notable changes suggestive of enlargement - inf. lateral ventricle appears within normal size limits with no apparent enlargement - no observable enlargement of the 3rd ventricle - no clear enlargement or abnormal growth seen in the external csf For the cerebral cortex: - the frontal lobe shows no notable changes suggestive of atrophy - no appreciable degenerative or atrophic changes observed in the parietal lobe - no observable atrophic changes in the limbic cortex - no findings suggestive of atrophy are seen in the temporal lobe - no findings suggestive of atrophy are seen in the occipital lobe - insular cortex appears preserved, with no observable tissue loss For the subcortical structures: - hippocampus appears preserved, with no observable tissue loss - basal forebrain demonstrates a healthy morphology without signs of atrophy - the putamen shows no notable changes suggestive of atrophy - accumbens demonstrates a healthy morphology without signs of atrophy - amygdala appears preserved, with no observable tissue loss - mild atrophy of the left thalamus; the right thalamus is normal - caudate maintains a normal appearance with no observable atrophic features - pallidum maintains a normal appearance with no observable atrophic features - no appreciable degenerative or atrophic changes observed in the ventral dc
CN
FTLD_203568133_01336_MR_Sagittal_MP-Rage_br_raw_20230206172305267_I10182049
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild-to-moderate atrophy of the left thalamus; normal-to-mild atrophy of the right thalamus - moderate atrophy of the left pallidum and mild-to-moderate atrophy of the right pallidum - mild-to-moderate atrophy of the left putamen and mild atrophy of the right putamen - amygdala appears within normal limits without apparent atrophy - mild-to-moderate atrophy of the left hippocampus - moderate atrophy of the left caudate and mild atrophy of the right caudate - the basal forebrain shows no notable changes suggestive of atrophy - mild-to-moderate atrophy of the left ventral dc and mild atrophy of the right ventral dc - no evident atrophy or tissue thinning seen in the accumbens For the ventricles: - mild enlargement of the external csf - no observable enlargement of the 4th ventricle - mild enlargement of the 3rd ventricle - moderate-to-severe enlargement of the left lateral ventricle and moderate enlargement of the right lateral ventricle - moderate-to-severe enlargement of the left inf. lateral ventricle; normal-to-mild enlargement of the right inf. lateral ventricle For the cerebral cortex: - moderate-to-severe atrophy of the left frontal lobe and mild-to-moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: frontal pole (mild-to-moderate atrophy both left/right), middle frontal gyrus (moderate atrophy on the left and mild atrophy on the right), sup. frontal gyrus (mild atrophy both left/right), lateral orbital gyrus (mild-to-moderate atrophy on the left and normal on the right), precentral gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), opercular inf. frontal gyrus (mild atrophy on the left and normal on the right), precentral gyrus medial segment (mild atrophy on the left and normal on the right), gyrus rectus (mild atrophy on the left and normal on the right), medial orbital gyrus (mild atrophy on the left and normal on the right) and supplementary motor cortex (normal on the left and mild atrophy on the right) - no findings suggestive of atrophy are seen in the occipital lobe - temporal lobe demonstrates a healthy morphology without signs of atrophy - parietal lobe appears within normal limits without apparent atrophy - mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy both left/right) and middle cingulate gyrus (mild atrophy on the left) - mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: frontal operculum (mild-to-moderate atrophy on the left and normal on the right) and anterior insula (mild atrophy on the left and normal on the right)
BV
FTLD_203881162_02268_MR_Sagittal_MP-Rage_br_raw_20230206155428347_I10181486
On a T1-weighted brain MRI we observed: For the subcortical structures: - no findings suggestive of atrophy are seen in the thalamus - mild-to-moderate atrophy of the left accumbens and mild atrophy of the right accumbens - mild atrophy of the right ventral dc; normal-to-mild atrophy of the left ventral dc - amygdala maintains a normal appearance with no observable atrophic features - mild-to-moderate atrophy of the left caudate and mild atrophy of the right caudate - no evident atrophy or tissue thinning seen in the basal forebrain - mild bilateral atrophy of the pallidum - the hippocampus shows no notable changes suggestive of atrophy - mild atrophy of the left putamen; normal-to-mild atrophy of the right putamen For the ventricles: - 4th ventricle appears to be of normal dimensions, with no observable increase in size - no observable enlargement of the inf. lateral ventricle - no appreciable enlargement noted in the 3rd ventricle - mild enlargement of the external csf - mild bilateral enlargement of the lateral ventricle For the cerebral cortex: - insular cortex appears preserved, with no observable tissue loss - no evident atrophy or tissue thinning seen in the temporal lobe - parietal lobe appears within normal limits without apparent atrophy - limbic cortex appears preserved, with no observable tissue loss - moderate-to-severe atrophy of the left frontal lobe and moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: frontal pole (moderate atrophy on the left and mild-to-moderate atrophy on the right), middle frontal gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), gyrus rectus (mild atrophy on the left and mild-to-moderate atrophy on the right), anterior orbital gyrus (mild atrophy both left/right), triangular inf. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), medial frontal cortex (mild-to-moderate atrophy on the right), lateral orbital gyrus (mild-to-moderate atrophy on the left and normal on the right), sup. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), sup. frontal gyrus medial segment (mild atrophy on the left and normal-to-mild atrophy on the right), supplementary motor cortex (mild atrophy on the left and normal-to-mild atrophy on the right) and opercular inf. frontal gyrus (normal on the left and mild atrophy on the right) - occipital lobe appears preserved, with no observable tissue loss
BV
ADNI_037_S_5162_MR_MPRAGE_br_raw_20130503091904515_4_S188623_I369977
On a T1-weighted brain MRI we observed: For the subcortical structures: - thalamus demonstrates a healthy morphology without signs of atrophy - no appreciable degenerative or atrophic changes observed in the basal forebrain - the left hippocampus volume is borderline low - the left hippocampus volume is borderline low - mild atrophy of the right amygdala; the left amygdala is normal - ventral dc appears within normal limits without apparent atrophy - pallidum appears within normal limits without apparent atrophy - accumbens appears within normal limits without apparent atrophy - mild atrophy of the right caudate; the left caudate is normal - mild atrophy of the left putamen; normal-to-mild atrophy of the right putamen For the cerebral cortex: - no clear atrophic alterations are visible in the occipital lobe - no findings suggestive of atrophy are seen in the limbic cortex - mild bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: planum temporale (normal-to-mild atrophy on the left and mild atrophy on the right), middle temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), temporal pole (normal on the left and mild atrophy on the right) and planum polare (mild atrophy on the left and normal on the right) - frontal lobe appears within normal limits without apparent atrophy - mild bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: central operculum (mild atrophy both left/right) and posterior insula (normal on the left and mild atrophy on the right) - parietal lobe appears preserved, with no observable tissue loss For the ventricles: - mild-to-moderate enlargement of the 3rd ventricle - no appreciable enlargement noted in the lateral ventricle - mild bilateral enlargement of the inf. lateral ventricle - mild enlargement of the external csf - the 4th ventricle shows no notable changes suggestive of enlargement
AD
ADNI_051_S_5005_MR_MPRAGE_GRAPPA2_br_raw_20121106153303625_111_S173397_I344142
On a T1-weighted brain MRI we observed: For the ventricles: - no clear enlargement or abnormal growth seen in the 4th ventricle - mild-to-moderate enlargement of the 3rd ventricle - external csf maintains a typical volume without observable enlargement - severe bilateral enlargement of the inf. lateral ventricle - moderate enlargement of the left lateral ventricle and moderate-to-severe enlargement of the right lateral ventricle For the cerebral cortex: - frontal lobe demonstrates a healthy morphology without signs of atrophy - occipital lobe maintains a normal appearance with no observable atrophic features - mild-to-moderate bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: middle temporal gyrus (mild atrophy both left/right), sup. temporal gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), inf. temporal gyrus (normal on the left and mild atrophy on the right) and transverse temporal gyrus (mild atrophy on the left and normal on the right) - mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (mild atrophy on the left and mild-to-moderate atrophy on the right), posterior cingulate gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and parahippocampal gyrus (mild atrophy on the left and normal on the right) - mild atrophy of the right insular cortex; the left insular cortex is normal; focal volume loss observed in the following subregions: frontal operculum (normal-to-mild atrophy on the left and mild atrophy on the right) and parietal operculum (normal-to-mild atrophy on the left and mild atrophy on the right) - no findings suggestive of atrophy are seen in the parietal lobe For the subcortical structures: - moderate-to-severe atrophy of the left amygdala and mild atrophy of the right amygdala - putamen appears preserved, with no observable tissue loss - no observable atrophic changes in the basal forebrain - no observable atrophic changes in the thalamus - mild bilateral atrophy of the accumbens - mild atrophy of the left hippocampus - mild-to-moderate atrophy of the right hippocampus - no observable atrophic changes in the ventral dc - no appreciable degenerative or atrophic changes observed in the pallidum - mild bilateral atrophy of the caudate
AD
FTLD_203307240_03040_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10177390
On a T1-weighted brain MRI we observed: For the ventricles: - mild enlargement of the left lateral ventricle; the right lateral ventricle is normal - 3rd ventricle appears to be of normal dimensions, with no observable increase in size - moderate-to-severe enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal - no findings suggestive of enlargement are seen in the external csf - no observable enlargement of the 4th ventricle For the subcortical structures: - putamen maintains a normal appearance with no observable atrophic features - the basal forebrain shows no notable changes suggestive of atrophy - moderate-to-severe atrophy of the left amygdala and mild-to-moderate atrophy of the right amygdala - the caudate shows no notable changes suggestive of atrophy - mild atrophy of the left pallidum; the right pallidum is normal - thalamus maintains a normal appearance with no observable atrophic features - mild atrophy of the left hippocampus - accumbens appears within normal limits without apparent atrophy - mild atrophy of the left ventral dc; the right ventral dc is normal For the cerebral cortex: - mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and normal on the right) - no evident atrophy or tissue thinning seen in the parietal lobe - mild atrophy of the left limbic cortex; normal-to-mild atrophy of the right limbic cortex; focal volume loss observed in the following subregions: entorhinal area (mild atrophy on the left and normal-to-mild atrophy on the right) - no findings suggestive of atrophy are seen in the occipital lobe - no observable atrophic changes in the frontal lobe - severe atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (severe atrophy on the left and mild atrophy on the right), fusiform gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), inf. temporal gyrus (moderate atrophy on the left), planum polare (mild-to-moderate atrophy on the left and normal on the right), sup. temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), transverse temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), planum temporale (normal on the left and mild atrophy on the right) and middle temporal gyrus (mild atrophy on the left)
SV
ADNI_002_S_6404_MR_Accelerated_Sagittal_MPRAGE__br_raw_20180716145110946_12_S705039_I1021530
On a T1-weighted brain MRI we observed: For the subcortical structures: - basal forebrain demonstrates a healthy morphology without signs of atrophy - no evident atrophy or tissue thinning seen in the hippocampus - amygdala appears within normal limits without apparent atrophy - no evident atrophy or tissue thinning seen in the thalamus - no appreciable degenerative or atrophic changes observed in the accumbens - pallidum demonstrates a healthy morphology without signs of atrophy - ventral dc appears within normal limits without apparent atrophy - caudate appears within normal limits without apparent atrophy - putamen maintains a normal appearance with no observable atrophic features For the cerebral cortex: - insular cortex appears within normal limits without apparent atrophy - no findings suggestive of atrophy are seen in the parietal lobe - the temporal lobe shows no notable changes suggestive of atrophy - limbic cortex demonstrates a healthy morphology without signs of atrophy - frontal lobe demonstrates a healthy morphology without signs of atrophy - no clear atrophic alterations are visible in the occipital lobe For the ventricles: - external csf appears within normal size limits with no apparent enlargement - inf. lateral ventricle appears to be of normal dimensions, with no observable increase in size - mild enlargement of the right lateral ventricle; the left lateral ventricle is normal - the 3rd ventricle shows no notable changes suggestive of enlargement - moderate-to-severe enlargement of the 4th ventricle
CN
ADNI_012_S_4545_MR_MPRAGE_SENSE2__br_raw_20120315112934375_1_S143908_I290409
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no evident atrophy or tissue thinning seen in the frontal lobe - no findings suggestive of atrophy are seen in the temporal lobe - no observable atrophic changes in the occipital lobe - no appreciable degenerative or atrophic changes observed in the limbic cortex - no observable atrophic changes in the parietal lobe - insular cortex maintains a normal appearance with no observable atrophic features For the ventricles: - no evident size increase noted in the 3rd ventricle - no evident size increase noted in the inf. lateral ventricle - no evident size increase noted in the 4th ventricle - external csf maintains its expected proportions without signs of enlargement - lateral ventricle appears to be of normal dimensions, with no observable increase in size For the subcortical structures: - amygdala appears preserved, with no observable tissue loss - no clear atrophic alterations are visible in the thalamus - accumbens appears within normal limits without apparent atrophy - the ventral dc shows no notable changes suggestive of atrophy - no findings suggestive of atrophy are seen in the caudate - mild atrophy of the right pallidum; normal-to-mild atrophy of the left pallidum - no observable atrophic changes in the hippocampus - putamen maintains a normal appearance with no observable atrophic features - mild atrophy of the right basal forebrain; normal-to-mild atrophy of the left basal forebrain
CN
ADNI_057_S_0941_MR_MPR__GradWarp__B1_Correction__N3__Scaled_Br_20071115130532568_S42111_I82342
On a T1-weighted brain MRI we observed: For the ventricles: - mild enlargement of the 4th ventricle - mild-to-moderate enlargement of the external csf - severe enlargement of the left inf. lateral ventricle and mild-to-moderate enlargement of the right inf. lateral ventricle - mild-to-moderate bilateral enlargement of the lateral ventricle - no appreciable enlargement noted in the 3rd ventricle For the cerebral cortex: - mild bilateral atrophy of the occipital lobe; focal volume loss observed in the following subregions: calcarine cortex (mild atrophy on the left and normal-to-mild atrophy on the right) and sup. occipital gyrus (normal on the left and mild atrophy on the right) - mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the left) and entorhinal area (mild atrophy on the left and normal on the right) - moderate-to-severe atrophy of the left parietal lobe and mild atrophy of the right parietal lobe; focal volume loss observed in the following subregions: angular gyrus (mild atrophy both left/right), supramarginal gyrus (mild-to-moderate atrophy on the left and normal on the right), postcentral gyrus (normal on the left and mild atrophy on the right), precuneus (mild atrophy on the left and normal on the right) and sup. parietal lobule (mild atrophy on the left) - mild bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: parietal operculum (normal on the left and mild atrophy on the right), anterior insula (mild atrophy on the left and normal on the right) and posterior insula (mild atrophy on the left and normal on the right) - moderate atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), inf. temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), middle temporal gyrus (mild-to-moderate atrophy on the left and normal on the right) and temporal pole (mild atrophy on the left and normal on the right) - the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in precentral gyrus medial segment (moderate atrophy on the left and normal on the right), middle frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and orbital inf. frontal gyrus (mild atrophy on the right) For the subcortical structures: - the thalamus shows no notable changes suggestive of atrophy - no findings suggestive of atrophy are seen in the basal forebrain - mild atrophy of the left hippocampus - mild-to-moderate atrophy of the right hippocampus - pallidum appears preserved, with no observable tissue loss - mild atrophy of the left caudate; normal-to-mild atrophy of the right caudate - no clear atrophic alterations are visible in the accumbens - moderate atrophy of the left amygdala and mild-to-moderate atrophy of the right amygdala - ventral dc maintains a normal appearance with no observable atrophic features - mild atrophy of the left putamen; the right putamen is normal
AD
ADNI_070_S_10377_MR_Accelerated_Sagittal_MPRAGE_MSV21_br_raw_20250325140312308_1_I11165020
On a T1-weighted brain MRI we observed: For the cerebral cortex: - the parietal lobe shows no notable changes suggestive of atrophy - the limbic cortex shows no notable changes suggestive of atrophy - no evident atrophy or tissue thinning seen in the temporal lobe - occipital lobe demonstrates a healthy morphology without signs of atrophy - no clear atrophic alterations are visible in the frontal lobe - no appreciable degenerative or atrophic changes observed in the insular cortex For the subcortical structures: - no findings suggestive of atrophy are seen in the caudate - putamen appears within normal limits without apparent atrophy - basal forebrain appears within normal limits without apparent atrophy - ventral dc demonstrates a healthy morphology without signs of atrophy - amygdala maintains a normal appearance with no observable atrophic features - accumbens appears within normal limits without apparent atrophy - no findings suggestive of atrophy are seen in the pallidum - hippocampus appears preserved, with no observable tissue loss - thalamus appears preserved, with no observable tissue loss For the ventricles: - 4th ventricle maintains its expected proportions without signs of enlargement - mild enlargement of the right inf. lateral ventricle; the left inf. lateral ventricle is normal - 3rd ventricle maintains a typical volume without observable enlargement - no evident size increase noted in the external csf - no evident size increase noted in the lateral ventricle
CN
FTLD_203175368_01867_MR_Sagittal_MP-Rage_br_raw_20230209093418458_I10183210
On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild-to-moderate atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: temporal pole (moderate atrophy on the left and normal-to-mild atrophy on the right), fusiform gyrus (mild atrophy both left/right) and middle temporal gyrus (mild atrophy on the left and normal on the right) - moderate atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (severe atrophy on the left and moderate atrophy on the right), frontal operculum (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), central operculum (mild atrophy on the left) and posterior insula (mild atrophy on the left and normal on the right) - severe atrophy of the left frontal lobe and mild-to-moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: gyrus rectus (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), frontal pole (mild-to-moderate atrophy both left/right), sup. frontal gyrus medial segment (mild-to-moderate atrophy on the left and mild atrophy on the right), triangular inf. frontal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), medial orbital gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), posterior orbital gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), middle frontal gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), sup. frontal gyrus (mild atrophy both left/right), orbital inf. frontal gyrus (mild-to-moderate atrophy on the left and normal on the right), medial frontal cortex (mild atrophy on the left and normal-to-mild atrophy on the right), lateral orbital gyrus (mild-to-moderate atrophy on the left), opercular inf. frontal gyrus (mild atrophy on the left and normal on the right) and anterior orbital gyrus (mild atrophy on the left) - moderate atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), entorhinal area (mild atrophy both left/right), posterior cingulate gyrus (mild atrophy on the left) and parahippocampal gyrus (mild atrophy on the left and normal on the right) - occipital lobe demonstrates a healthy morphology without signs of atrophy - no appreciable degenerative or atrophic changes observed in the parietal lobe For the subcortical structures: - severe atrophy of the left amygdala and moderate atrophy of the right amygdala - no clear atrophic alterations are visible in the pallidum - mild-to-moderate atrophy of the left caudate; the right caudate is normal - mild atrophy of the left hippocampus - mild atrophy of the left thalamus; normal-to-mild atrophy of the right thalamus - moderate-to-severe atrophy of the left putamen; the right putamen is normal - no appreciable degenerative or atrophic changes observed in the ventral dc - basal forebrain appears preserved, with no observable tissue loss - moderate atrophy of the left accumbens and mild atrophy of the right accumbens For the ventricles: - mild enlargement of the left lateral ventricle; normal-to-mild enlargement of the right lateral ventricle - moderate enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal - mild enlargement of the 4th ventricle - moderate enlargement of the external csf - mild-to-moderate enlargement of the 3rd ventricle
SV
FTLD_203167453_02356_MR_Sagittal_MPR_br_raw_20230206184743165_1.d_I10182645
On a T1-weighted brain MRI we observed: For the subcortical structures: - ventral dc maintains a normal appearance with no observable atrophic features - no evident atrophy or tissue thinning seen in the accumbens - no observable atrophic changes in the thalamus - no evident atrophy or tissue thinning seen in the basal forebrain - mild bilateral atrophy of the pallidum - no observable atrophic changes in the amygdala - mild-to-moderate atrophy of the left hippocampus - mild atrophy of the right hippocampus - putamen appears preserved, with no observable tissue loss - mild-to-moderate bilateral atrophy of the caudate For the ventricles: - no clear enlargement or abnormal growth seen in the 3rd ventricle - inf. lateral ventricle appears within normal size limits with no apparent enlargement - mild bilateral enlargement of the lateral ventricle - external csf maintains its expected proportions without signs of enlargement - mild enlargement of the 4th ventricle For the cerebral cortex: - no findings suggestive of atrophy are seen in the frontal lobe - no findings suggestive of atrophy are seen in the insular cortex - limbic cortex appears preserved, with no observable tissue loss - parietal lobe maintains a normal appearance with no observable atrophic features - no appreciable degenerative or atrophic changes observed in the occipital lobe - the temporal lobe shows no notable changes suggestive of atrophy
BV
ADNI_032_S_0095_MR_MPR____N3__Scaled_Br_20070731174115956_S10729_I63424
On a T1-weighted brain MRI we observed: For the subcortical structures: - the caudate shows no notable changes suggestive of atrophy - no clear atrophic alterations are visible in the accumbens - pallidum demonstrates a healthy morphology without signs of atrophy - basal forebrain appears within normal limits without apparent atrophy - the putamen shows no notable changes suggestive of atrophy - no findings suggestive of atrophy are seen in the thalamus - hippocampus appears preserved, with no observable tissue loss - ventral dc appears within normal limits without apparent atrophy - amygdala demonstrates a healthy morphology without signs of atrophy For the cerebral cortex: - the temporal lobe shows no notable changes suggestive of atrophy - insular cortex appears preserved, with no observable tissue loss - no clear atrophic alterations are visible in the occipital lobe - no evident atrophy or tissue thinning seen in the frontal lobe - mild atrophy of the left parietal lobe; normal-to-mild atrophy of the right parietal lobe; focal volume loss observed in the following subregions: precuneus (mild atrophy on the left and normal on the right) - no findings suggestive of atrophy are seen in the limbic cortex For the ventricles: - 3rd ventricle maintains a typical volume without observable enlargement - no evident size increase noted in the lateral ventricle - no observable enlargement of the 4th ventricle - inf. lateral ventricle maintains a typical volume without observable enlargement - the external csf shows no notable changes suggestive of enlargement
CN
ADNI_067_S_4782_MR_Accelerated_Sagittal_MPRAGE__br_raw_20211006133310138_115_S1070028_I1500995
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild bilateral atrophy of the putamen - pallidum maintains a normal appearance with no observable atrophic features - ventral dc demonstrates a healthy morphology without signs of atrophy - mild atrophy of the left caudate; normal-to-mild atrophy of the right caudate - mild atrophy of the right thalamus; the left thalamus is normal - moderate-to-severe bilateral atrophy of the amygdala - moderate atrophy of the left hippocampus - moderate-to-severe atrophy of the right hippocampus - basal forebrain demonstrates a healthy morphology without signs of atrophy - mild bilateral atrophy of the accumbens For the ventricles: - mild enlargement of the left inf. lateral ventricle and mild-to-moderate enlargement of the right inf. lateral ventricle - mild bilateral enlargement of the lateral ventricle - 4th ventricle appears to be of normal dimensions, with no observable increase in size - mild enlargement of the external csf - mild-to-moderate enlargement of the 3rd ventricle For the cerebral cortex: - mild-to-moderate atrophy of the left parietal lobe; normal-to-mild atrophy of the right parietal lobe; focal volume loss observed in the following subregions: precuneus (mild atrophy on the left and normal-to-mild atrophy on the right) and supramarginal gyrus (mild atrophy on the left) - mild-to-moderate bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: precentral gyrus medial segment (mild-to-moderate atrophy on the left), medial orbital gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), triangular inf. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), posterior orbital gyrus (mild atrophy on the left and normal on the right), sup. frontal gyrus medial segment (mild atrophy on the left and normal on the right), gyrus rectus (mild atrophy on the left and normal on the right), orbital inf. frontal gyrus (mild atrophy on the left and normal on the right) and precentral gyrus (normal on the left and mild atrophy on the right) - insular cortex demonstrates a healthy morphology without signs of atrophy - mild-to-moderate atrophy of the right limbic cortex; normal-to-mild atrophy of the left limbic cortex; focal volume loss observed in the following subregions: parahippocampal gyrus (mild-to-moderate atrophy both left/right) and entorhinal area (mild atrophy both left/right) - mild atrophy of the right temporal lobe; normal-to-mild atrophy of the left temporal lobe; focal volume loss observed in the following subregions: fusiform gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and temporal pole (normal-to-mild atrophy on the left and mild atrophy on the right) - mild atrophy of the right occipital lobe; the left occipital lobe is normal; focal volume loss observed in the following subregions: sup. occipital gyrus (mild atrophy both left/right) and middle occipital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right)
AD
FTLD_203807239_02930_MR_Accelerated_Sagittal_IR-FSPGR_br_raw_202_I10176979
On a T1-weighted brain MRI we observed: For the ventricles: - mild-to-moderate enlargement of the external csf - mild-to-moderate bilateral enlargement of the inf. lateral ventricle - 3rd ventricle appears to be of normal dimensions, with no observable increase in size - no appreciable enlargement noted in the 4th ventricle - mild bilateral enlargement of the lateral ventricle For the cerebral cortex: - parietal lobe appears preserved, with no observable tissue loss - no evident atrophy or tissue thinning seen in the limbic cortex - moderate-to-severe atrophy of the left frontal lobe and mild-to-moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), frontal pole (mild atrophy both left/right), orbital inf. frontal gyrus (mild atrophy both left/right), sup. frontal gyrus (mild atrophy both left/right), opercular inf. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), lateral orbital gyrus (normal on the left and mild-to-moderate atrophy on the right), anterior orbital gyrus (normal on the left and mild atrophy on the right), precentral gyrus (mild atrophy on the left and normal on the right) and supplementary motor cortex (mild atrophy on the left) - no evident atrophy or tissue thinning seen in the occipital lobe - no findings suggestive of atrophy are seen in the insular cortex - no observable atrophic changes in the temporal lobe For the subcortical structures: - mild atrophy of the right accumbens; normal-to-mild atrophy of the left accumbens - mild-to-moderate atrophy of the left caudate and mild atrophy of the right caudate - no clear atrophic alterations are visible in the amygdala - no observable atrophic changes in the thalamus - mild-to-moderate atrophy of the left pallidum; normal-to-mild atrophy of the right pallidum - the left hippocampus volume is borderline low - no evident atrophy or tissue thinning seen in the ventral dc - the basal forebrain shows no notable changes suggestive of atrophy - moderate atrophy of the left putamen; normal-to-mild atrophy of the right putamen
PNFA
FTLD_203489181_03188_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10176905
On a T1-weighted brain MRI we observed: For the subcortical structures: - pallidum appears within normal limits without apparent atrophy - mild atrophy of the left accumbens; the right accumbens is normal - no evident atrophy or tissue thinning seen in the caudate - putamen maintains a normal appearance with no observable atrophic features - no evident atrophy or tissue thinning seen in the ventral dc - no findings suggestive of atrophy are seen in the thalamus - the left hippocampus volume is borderline low - no appreciable degenerative or atrophic changes observed in the amygdala - basal forebrain appears preserved, with no observable tissue loss For the ventricles: - mild enlargement of the 4th ventricle - no evident size increase noted in the external csf - mild-to-moderate enlargement of the right inf. lateral ventricle; the left inf. lateral ventricle is normal - mild enlargement of the 3rd ventricle - mild-to-moderate bilateral enlargement of the lateral ventricle For the cerebral cortex: - no findings suggestive of atrophy are seen in the occipital lobe - frontal lobe demonstrates a healthy morphology without signs of atrophy - mild-to-moderate bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: anterior insula (mild atrophy both left/right), central operculum (normal-to-mild atrophy on the left and mild atrophy on the right), posterior insula (normal on the left and mild atrophy on the right), frontal operculum (mild atrophy on the left and normal on the right) and parietal operculum (mild atrophy on the left and normal on the right) - temporal lobe appears within normal limits without apparent atrophy - no appreciable degenerative or atrophic changes observed in the parietal lobe - limbic cortex maintains a normal appearance with no observable atrophic features
BV
FTLD_203447962_03264_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10177413
On a T1-weighted brain MRI we observed: For the ventricles: - severe bilateral enlargement of the inf. lateral ventricle - mild enlargement of the external csf - mild enlargement of the right lateral ventricle; the left lateral ventricle is normal - mild enlargement of the 3rd ventricle - no clear enlargement or abnormal growth seen in the 4th ventricle For the subcortical structures: - mild-to-moderate atrophy of the left caudate and mild atrophy of the right caudate - basal forebrain appears within normal limits without apparent atrophy - mild atrophy of the left pallidum and moderate atrophy of the right pallidum - severe bilateral atrophy of the amygdala - moderate-to-severe atrophy of the left accumbens and severe atrophy of the right accumbens - ventral dc appears preserved, with no observable tissue loss - mild atrophy of the left hippocampus - mild-to-moderate atrophy of the right hippocampus - no findings suggestive of atrophy are seen in the thalamus - mild atrophy of the left putamen and severe atrophy of the right putamen For the cerebral cortex: - occipital lobe appears preserved, with no observable tissue loss - mild atrophy of the left insular cortex and moderate atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and severe atrophy on the right) and posterior insula (mild atrophy on the left and mild-to-moderate atrophy on the right) - mild-to-moderate bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: entorhinal area (moderate atrophy both left/right), anterior cingulate gyrus (mild atrophy both left/right) and parahippocampal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) - no findings suggestive of atrophy are seen in the parietal lobe - severe bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy both left/right), fusiform gyrus (mild-to-moderate atrophy on the left and moderate atrophy on the right), inf. temporal gyrus (mild-to-moderate atrophy on the left and moderate atrophy on the right), sup. temporal gyrus (mild atrophy on the left and moderate atrophy on the right) and middle temporal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right) - frontal lobe maintains a normal appearance with no observable atrophic features
SV
ADNI_129_S_6763_MR_Accelerated_Sag_IR-FSPGR___br_raw_20200729143138118_83_S950284_I1326101
On a T1-weighted brain MRI we observed: For the cerebral cortex: - limbic cortex appears within normal limits without apparent atrophy - parietal lobe appears within normal limits without apparent atrophy - no appreciable degenerative or atrophic changes observed in the occipital lobe - no appreciable degenerative or atrophic changes observed in the temporal lobe - no appreciable degenerative or atrophic changes observed in the insular cortex - no observable atrophic changes in the frontal lobe For the subcortical structures: - no appreciable degenerative or atrophic changes observed in the ventral dc - no observable atrophic changes in the putamen - thalamus appears within normal limits without apparent atrophy - hippocampus maintains a normal appearance with no observable atrophic features - no findings suggestive of atrophy are seen in the accumbens - no appreciable degenerative or atrophic changes observed in the pallidum - mild bilateral atrophy of the caudate - basal forebrain maintains a normal appearance with no observable atrophic features - no findings suggestive of atrophy are seen in the amygdala For the ventricles: - no findings suggestive of enlargement are seen in the 4th ventricle - mild-to-moderate enlargement of the external csf - no observable enlargement of the inf. lateral ventricle - lateral ventricle appears to be of normal dimensions, with no observable increase in size - the 3rd ventricle shows no notable changes suggestive of enlargement
AD
ADNI_035_S_7050_MR_Accelerated_Sagittal_MPRAGE_Phase_A-P__br_raw_20220321155010010_136_S1116123_I1558920
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no findings suggestive of atrophy are seen in the frontal lobe - no evident atrophy or tissue thinning seen in the insular cortex - no findings suggestive of atrophy are seen in the occipital lobe - the parietal lobe shows no notable changes suggestive of atrophy - no clear atrophic alterations are visible in the limbic cortex - no observable atrophic changes in the temporal lobe For the ventricles: - the inf. lateral ventricle shows no notable changes suggestive of enlargement - the 4th ventricle shows no notable changes suggestive of enlargement - external csf appears within normal size limits with no apparent enlargement - no evident size increase noted in the lateral ventricle - no findings suggestive of enlargement are seen in the 3rd ventricle For the subcortical structures: - no observable atrophic changes in the basal forebrain - no appreciable degenerative or atrophic changes observed in the caudate - amygdala maintains a normal appearance with no observable atrophic features - no observable atrophic changes in the ventral dc - no clear atrophic alterations are visible in the putamen - pallidum appears within normal limits without apparent atrophy - no evident atrophy or tissue thinning seen in the accumbens - the hippocampus shows no notable changes suggestive of atrophy - thalamus appears preserved, with no observable tissue loss
CN
FTLD_203628476_03672_MR_Accelerated_Sagittal_IR-FSPGR_br_raw_202_I10451045
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no findings suggestive of atrophy are seen in the limbic cortex - the occipital lobe shows no notable changes suggestive of atrophy - mild atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: sup. temporal gyrus (mild atrophy on the left), planum temporale (moderate atrophy on the left and normal on the right), transverse temporal gyrus (mild atrophy on the left) and temporal pole (mild atrophy on the left and normal on the right) - the frontal lobe shows no notable changes suggestive of atrophy - the insular cortex shows no notable changes suggestive of atrophy - mild atrophy of the left parietal lobe; the right parietal lobe is normal For the subcortical structures: - moderate atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens - moderate atrophy of the left caudate and mild-to-moderate atrophy of the right caudate - mild-to-moderate atrophy of the left putamen and mild atrophy of the right putamen - mild atrophy of the right amygdala; normal-to-mild atrophy of the left amygdala - mild-to-moderate atrophy of the left ventral dc and mild atrophy of the right ventral dc - moderate-to-severe atrophy of the left pallidum and mild atrophy of the right pallidum - the left hippocampus volume is borderline low - the left hippocampus volume is borderline low - basal forebrain appears preserved, with no observable tissue loss - mild-to-moderate atrophy of the left thalamus and mild atrophy of the right thalamus For the ventricles: - mild-to-moderate bilateral enlargement of the lateral ventricle - mild-to-moderate enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle - mild enlargement of the external csf - mild-to-moderate enlargement of the 3rd ventricle - 4th ventricle maintains a typical volume without observable enlargement
PNFA
FTLD_203961383_03386_MR_Accelerated_Sagittal_MPRAGE_TEST_br_raw_2_I10450649
On a T1-weighted brain MRI we observed: For the ventricles: - moderate-to-severe enlargement of the external csf - moderate enlargement of the 3rd ventricle - mild enlargement of the right lateral ventricle; the left lateral ventricle is normal - severe bilateral enlargement of the inf. lateral ventricle - no appreciable enlargement noted in the 4th ventricle For the subcortical structures: - basal forebrain appears preserved, with no observable tissue loss - mild-to-moderate atrophy of the right pallidum; the left pallidum is normal - no appreciable degenerative or atrophic changes observed in the ventral dc - thalamus appears within normal limits without apparent atrophy - mild atrophy of the left hippocampus - mild-to-moderate atrophy of the right hippocampus - moderate atrophy of the right putamen; normal-to-mild atrophy of the left putamen - severe bilateral atrophy of the amygdala - mild-to-moderate atrophy of the left accumbens and severe atrophy of the right accumbens - mild atrophy of the left caudate and moderate-to-severe atrophy of the right caudate For the cerebral cortex: - mild-to-moderate atrophy of the right insular cortex; the left insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (mild-to-moderate atrophy on the left and moderate atrophy on the right) and posterior insula (normal on the left and mild-to-moderate atrophy on the right) - parietal lobe demonstrates a healthy morphology without signs of atrophy - moderate atrophy of the left temporal lobe and severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy on the left and severe atrophy on the right), inf. temporal gyrus (moderate atrophy on the left and moderate-to-severe atrophy on the right), fusiform gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), middle temporal gyrus (normal on the left and moderate-to-severe atrophy on the right), sup. temporal gyrus (mild-to-moderate atrophy on the right) and planum polare (normal on the left and mild atrophy on the right) - the occipital lobe shows no notable changes suggestive of atrophy - moderate-to-severe atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (mild atrophy on the left and mild-to-moderate atrophy on the right), parahippocampal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), anterior cingulate gyrus (normal on the left and moderate atrophy on the right) and middle cingulate gyrus (mild atrophy on the right) - the frontal lobe shows no notable changes suggestive of atrophy
SV
ADNI_068_S_0872_MR_MT1__N3m_Br_20120105155848721_S126380_I275484
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild atrophy of the right basal forebrain; normal-to-mild atrophy of the left basal forebrain - no observable atrophic changes in the caudate - moderate-to-severe atrophy of the left hippocampus - mild-to-moderate atrophy of the right hippocampus - amygdala maintains a normal appearance with no observable atrophic features - mild bilateral atrophy of the thalamus - pallidum demonstrates a healthy morphology without signs of atrophy - no evident atrophy or tissue thinning seen in the putamen - mild atrophy of the left ventral dc; normal-to-mild atrophy of the right ventral dc - no clear atrophic alterations are visible in the accumbens For the cerebral cortex: - insular cortex maintains a normal appearance with no observable atrophic features - no evident atrophy or tissue thinning seen in the temporal lobe - frontal lobe maintains a normal appearance with no observable atrophic features - no observable atrophic changes in the parietal lobe - no clear atrophic alterations are visible in the limbic cortex - mild atrophy of the left occipital lobe; the right occipital lobe is normal; focal volume loss observed in the following subregions: occipital fusiform gyrus (mild atrophy on the left) For the ventricles: - inf. lateral ventricle maintains its expected proportions without signs of enlargement - external csf appears to be of normal dimensions, with no observable increase in size - no appreciable enlargement noted in the 4th ventricle - 3rd ventricle maintains a typical volume without observable enlargement - lateral ventricle maintains its expected proportions without signs of enlargement
AD
FTLD_203756460_03065_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10177394
On a T1-weighted brain MRI we observed: For the subcortical structures: - thalamus appears preserved, with no observable tissue loss - the pallidum shows no notable changes suggestive of atrophy - no clear atrophic alterations are visible in the accumbens - mild atrophy of the left caudate; normal-to-mild atrophy of the right caudate - the basal forebrain shows no notable changes suggestive of atrophy - the putamen shows no notable changes suggestive of atrophy - moderate-to-severe atrophy of the left amygdala and moderate atrophy of the right amygdala - ventral dc maintains a normal appearance with no observable atrophic features - mild atrophy of the left hippocampus For the ventricles: - no appreciable enlargement noted in the 4th ventricle - severe enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle - mild enlargement of the 3rd ventricle - mild-to-moderate enlargement of the external csf - lateral ventricle appears within normal size limits with no apparent enlargement For the cerebral cortex: - no evident atrophy or tissue thinning seen in the insular cortex - mild atrophy of the left frontal lobe; normal-to-mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), medial frontal cortex (mild atrophy on the left and normal-to-mild atrophy on the right), anterior orbital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), gyrus rectus (mild atrophy on the left and normal on the right) and posterior orbital gyrus (normal on the left and mild atrophy on the right) - mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (mild-to-moderate atrophy on the left and mild atrophy on the right), parahippocampal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and middle cingulate gyrus (mild atrophy on the left) - parietal lobe demonstrates a healthy morphology without signs of atrophy - no appreciable degenerative or atrophic changes observed in the occipital lobe - moderate atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate atrophy on the left and mild-to-moderate atrophy on the right), fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), inf. temporal gyrus (mild atrophy on the left and normal on the right) and middle temporal gyrus (mild atrophy on the left and normal on the right)
SV
ADNI_012_S_5157_MR_MPRAGE_br_raw_20130517143346124_1_S189829_I372891
On a T1-weighted brain MRI we observed: For the ventricles: - no clear enlargement or abnormal growth seen in the inf. lateral ventricle - no appreciable enlargement noted in the lateral ventricle - mild-to-moderate enlargement of the external csf - no appreciable enlargement noted in the 4th ventricle - no observable enlargement of the 3rd ventricle For the subcortical structures: - no findings suggestive of atrophy are seen in the ventral dc - no findings suggestive of atrophy are seen in the basal forebrain - no appreciable degenerative or atrophic changes observed in the accumbens - mild atrophy of the left hippocampus - no observable atrophic changes in the amygdala - mild-to-moderate atrophy of the left thalamus and mild atrophy of the right thalamus - no findings suggestive of atrophy are seen in the putamen - mild bilateral atrophy of the caudate - no appreciable degenerative or atrophic changes observed in the pallidum For the cerebral cortex: - the temporal lobe shows no notable changes suggestive of atrophy - mild bilateral atrophy of the parietal lobe; focal volume loss observed in the following subregions: precuneus (normal-to-mild atrophy on the left and mild atrophy on the right), supramarginal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and angular gyrus (mild atrophy on the left) - no findings suggestive of atrophy are seen in the occipital lobe - no evident atrophy or tissue thinning seen in the limbic cortex - mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (mild atrophy both left/right) and frontal operculum (mild atrophy on the left) - mild bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (mild atrophy both left/right), gyrus rectus (normal-to-mild atrophy on the left and mild atrophy on the right), medial frontal cortex (normal on the left and mild-to-moderate atrophy on the right), anterior orbital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), posterior orbital gyrus (mild atrophy on the right) and precentral gyrus medial segment (mild atrophy on the left)
CN
FTLD_203644572_03274_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10176939
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild-to-moderate atrophy of the left putamen and mild atrophy of the right putamen - mild atrophy of the left thalamus; the right thalamus is normal - mild-to-moderate bilateral atrophy of the caudate - mild bilateral atrophy of the accumbens - no clear atrophic alterations are visible in the basal forebrain - ventral dc demonstrates a healthy morphology without signs of atrophy - mild-to-moderate atrophy of the left amygdala and mild atrophy of the right amygdala - mild bilateral atrophy of the pallidum - no findings suggestive of atrophy are seen in the hippocampus For the cerebral cortex: - mild atrophy of the left temporal lobe; normal-to-mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate atrophy on the left and mild-to-moderate atrophy on the right) - no observable atrophic changes in the occipital lobe - mild atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (mild atrophy both left/right) and central operculum (mild atrophy on the left) - no appreciable degenerative or atrophic changes observed in the limbic cortex - mild atrophy of the left parietal lobe; normal-to-mild atrophy of the right parietal lobe; focal volume loss observed in the following subregions: postcentral gyrus medial segment (mild atrophy both left/right), precuneus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) and sup. parietal lobule (mild atrophy on the left and normal on the right) - severe atrophy of the left frontal lobe and moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), sup. frontal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), frontal pole (mild atrophy on the left and mild-to-moderate atrophy on the right), precentral gyrus (mild atrophy both left/right), sup. frontal gyrus medial segment (mild atrophy both left/right), opercular inf. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), precentral gyrus medial segment (mild atrophy on the left and normal-to-mild atrophy on the right) and supplementary motor cortex (mild atrophy on the left and normal-to-mild atrophy on the right) For the ventricles: - no evident size increase noted in the 3rd ventricle - severe enlargement of the external csf - inf. lateral ventricle maintains its expected proportions without signs of enlargement - 4th ventricle maintains a typical volume without observable enlargement - lateral ventricle appears to be of normal dimensions, with no observable increase in size
PNFA
ADNI_024_S_1171_MR_MPR__GradWarp__B1_Correction__N3__Scaled_Br_20070731172208570_S24659_I63406
On a T1-weighted brain MRI we observed: For the ventricles: - mild-to-moderate enlargement of the left lateral ventricle and moderate enlargement of the right lateral ventricle - no evident size increase noted in the external csf - moderate-to-severe enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle - mild enlargement of the 3rd ventricle - mild-to-moderate enlargement of the 4th ventricle For the subcortical structures: - mild bilateral atrophy of the thalamus - mild bilateral atrophy of the putamen - mild bilateral atrophy of the amygdala - the left hippocampus volume is borderline low - the left hippocampus volume is borderline low - pallidum appears within normal limits without apparent atrophy - mild atrophy of the left accumbens; the right accumbens is normal - caudate appears within normal limits without apparent atrophy - ventral dc appears within normal limits without apparent atrophy - the basal forebrain shows no notable changes suggestive of atrophy For the cerebral cortex: - the limbic cortex shows no notable changes suggestive of atrophy - mild-to-moderate atrophy of the left parietal lobe and mild atrophy of the right parietal lobe; focal volume loss observed in the following subregions: angular gyrus (mild atrophy both left/right) and precuneus (normal-to-mild atrophy on the left and mild atrophy on the right) - no evident atrophy or tissue thinning seen in the frontal lobe - temporal lobe appears within normal limits without apparent atrophy - no clear atrophic alterations are visible in the occipital lobe - no evident atrophy or tissue thinning seen in the insular cortex
AD
FTLD_203142083_03384_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10450647
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no observable atrophic changes in the frontal lobe - occipital lobe appears preserved, with no observable tissue loss - moderate atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: inf. temporal gyrus (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), temporal pole (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) and fusiform gyrus (mild atrophy on the left) - the parietal lobe shows no notable changes suggestive of atrophy - no observable atrophic changes in the insular cortex - no clear atrophic alterations are visible in the limbic cortex For the subcortical structures: - mild atrophy of the left hippocampus - no clear atrophic alterations are visible in the caudate - putamen appears within normal limits without apparent atrophy - moderate atrophy of the left amygdala; the right amygdala is normal - no observable atrophic changes in the pallidum - no findings suggestive of atrophy are seen in the ventral dc - accumbens demonstrates a healthy morphology without signs of atrophy - no appreciable degenerative or atrophic changes observed in the thalamus - the basal forebrain shows no notable changes suggestive of atrophy For the ventricles: - mild enlargement of the 3rd ventricle - severe enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal - no appreciable enlargement noted in the external csf - no findings suggestive of enlargement are seen in the 4th ventricle - lateral ventricle maintains a typical volume without observable enlargement
SV
FTLD_203447087_01784_MR_Sagittal_MP-Rage_br_raw_20230206184131678_I10182617
On a T1-weighted brain MRI we observed: For the ventricles: - the inf. lateral ventricle shows no notable changes suggestive of enlargement - 4th ventricle appears to be of normal dimensions, with no observable increase in size - no findings suggestive of enlargement are seen in the external csf - no appreciable enlargement noted in the lateral ventricle - 3rd ventricle maintains its expected proportions without signs of enlargement For the subcortical structures: - mild atrophy of the right amygdala; the left amygdala is normal - no appreciable degenerative or atrophic changes observed in the pallidum - the ventral dc shows no notable changes suggestive of atrophy - no findings suggestive of atrophy are seen in the accumbens - no evident atrophy or tissue thinning seen in the basal forebrain - no evident atrophy or tissue thinning seen in the putamen - no evident atrophy or tissue thinning seen in the hippocampus - no appreciable degenerative or atrophic changes observed in the thalamus - caudate demonstrates a healthy morphology without signs of atrophy For the cerebral cortex: - limbic cortex demonstrates a healthy morphology without signs of atrophy - no evident atrophy or tissue thinning seen in the insular cortex - no evident atrophy or tissue thinning seen in the parietal lobe - the temporal lobe shows no notable changes suggestive of atrophy - no appreciable degenerative or atrophic changes observed in the occipital lobe - frontal lobe appears within normal limits without apparent atrophy
CN
FTLD_203773746_03647_MR_Accelerated_Sagittal_MPRAGE_br_raw_20241_I11047639
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild-to-moderate atrophy of the left amygdala and mild atrophy of the right amygdala - thalamus maintains a normal appearance with no observable atrophic features - mild atrophy of the right pallidum; normal-to-mild atrophy of the left pallidum - no findings suggestive of atrophy are seen in the hippocampus - no evident atrophy or tissue thinning seen in the putamen - the accumbens shows no notable changes suggestive of atrophy - ventral dc appears preserved, with no observable tissue loss - basal forebrain maintains a normal appearance with no observable atrophic features - mild-to-moderate bilateral atrophy of the caudate For the ventricles: - no clear enlargement or abnormal growth seen in the inf. lateral ventricle - no findings suggestive of enlargement are seen in the 3rd ventricle - no evident size increase noted in the 4th ventricle - moderate enlargement of the external csf - the lateral ventricle shows no notable changes suggestive of enlargement For the cerebral cortex: - mild atrophy of the right limbic cortex; normal-to-mild atrophy of the left limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and parahippocampal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) - mild-to-moderate bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: gyrus rectus (mild atrophy on the left and normal-to-mild atrophy on the right), middle frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), precentral gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), orbital inf. frontal gyrus (mild atrophy on the left and normal on the right), lateral orbital gyrus (normal on the left and mild atrophy on the right), anterior orbital gyrus (mild atrophy on the left) and sup. frontal gyrus (mild atrophy on the left and normal on the right) - mild atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and normal-to-mild atrophy on the right) - mild atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: middle temporal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right) and planum polare (normal on the left and mild atrophy on the right) - occipital lobe demonstrates a healthy morphology without signs of atrophy - the parietal lobe shows no notable changes suggestive of atrophy
PNFA
ADNI_082_S_1079_MR_MPR__GradWarp__B1_Correction__N3__Scaled_Br_20070418082140556_S22650_I49490
On a T1-weighted brain MRI we observed: For the cerebral cortex: - moderate atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (mild atrophy on the left and mild-to-moderate atrophy on the right), parahippocampal gyrus (mild atrophy both left/right), middle cingulate gyrus (mild-to-moderate atrophy on the right) and anterior cingulate gyrus (mild atrophy on the right) - mild atrophy of the right insular cortex; normal-to-mild atrophy of the left insular cortex; focal volume loss observed in the following subregions: posterior insula (mild atrophy on the left and mild-to-moderate atrophy on the right), parietal operculum (normal on the left and mild-to-moderate atrophy on the right) and anterior insula (normal on the left and mild atrophy on the right) - no observable atrophic changes in the occipital lobe - mild bilateral atrophy of the parietal lobe; focal volume loss observed in the following subregions: angular gyrus (mild atrophy both left/right) and supramarginal gyrus (mild-to-moderate atrophy on the left and normal on the right) - mild atrophy of the left temporal lobe and moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: inf. temporal gyrus (mild-to-moderate atrophy both left/right), temporal pole (mild-to-moderate atrophy both left/right) and middle temporal gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right) - no clear atrophic alterations are visible in the frontal lobe For the subcortical structures: - moderate-to-severe atrophy of the left amygdala and severe atrophy of the right amygdala - basal forebrain appears within normal limits without apparent atrophy - no observable atrophic changes in the ventral dc - pallidum appears preserved, with no observable tissue loss - mild bilateral atrophy of the putamen - mild atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens - mild bilateral atrophy of the caudate - moderate atrophy of the left hippocampus - moderate-to-severe atrophy of the right hippocampus - no findings suggestive of atrophy are seen in the thalamus For the ventricles: - severe bilateral enlargement of the inf. lateral ventricle - no appreciable enlargement noted in the 4th ventricle - mild enlargement of the 3rd ventricle - mild-to-moderate bilateral enlargement of the lateral ventricle - no appreciable enlargement noted in the external csf
AD
ADNI_006_S_0675_MR_MPR-R__GradWarp__B1_Correction__N3__Scaled_Br_20081224111819875_S60800_I132229
On a T1-weighted brain MRI we observed: For the cerebral cortex: - occipital lobe appears within normal limits without apparent atrophy - parietal lobe maintains a normal appearance with no observable atrophic features - mild atrophy of the left temporal lobe and mild-to-moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (mild atrophy on the left and mild-to-moderate atrophy on the right), planum temporale (mild atrophy on the left and normal-to-mild atrophy on the right), inf. temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), fusiform gyrus (normal on the left and mild atrophy on the right) and sup. temporal gyrus (mild atrophy on the right) - no observable atrophic changes in the frontal lobe - no findings suggestive of atrophy are seen in the insular cortex - mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (mild atrophy on the left and mild-to-moderate atrophy on the right) and anterior cingulate gyrus (mild atrophy on the left) For the ventricles: - mild enlargement of the external csf - no findings suggestive of enlargement are seen in the lateral ventricle - 3rd ventricle maintains a typical volume without observable enlargement - moderate-to-severe enlargement of the right inf. lateral ventricle; normal-to-mild enlargement of the left inf. lateral ventricle - no appreciable enlargement noted in the 4th ventricle For the subcortical structures: - no clear atrophic alterations are visible in the caudate - no observable atrophic changes in the accumbens - mild bilateral atrophy of the pallidum - mild atrophy of the left hippocampus - mild atrophy of the right hippocampus - thalamus appears preserved, with no observable tissue loss - moderate-to-severe atrophy of the left amygdala and severe atrophy of the right amygdala - basal forebrain demonstrates a healthy morphology without signs of atrophy - no observable atrophic changes in the ventral dc - mild bilateral atrophy of the putamen
AD
FTLD_203979630_03037_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10176924
On a T1-weighted brain MRI we observed: For the subcortical structures: - ventral dc maintains a normal appearance with no observable atrophic features - mild atrophy of the left pallidum and mild-to-moderate atrophy of the right pallidum - severe bilateral atrophy of the amygdala - no clear atrophic alterations are visible in the basal forebrain - no observable atrophic changes in the thalamus - moderate-to-severe atrophy of the left hippocampus - severe atrophy of the right hippocampus - moderate atrophy of the left putamen and moderate-to-severe atrophy of the right putamen - moderate atrophy of the left accumbens and moderate-to-severe atrophy of the right accumbens - mild bilateral atrophy of the caudate For the ventricles: - no clear enlargement or abnormal growth seen in the external csf - mild-to-moderate enlargement of the 3rd ventricle - mild-to-moderate bilateral enlargement of the lateral ventricle - severe bilateral enlargement of the inf. lateral ventricle - 4th ventricle maintains a typical volume without observable enlargement For the cerebral cortex: - mild-to-moderate atrophy of the left temporal lobe and moderate-to-severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (mild-to-moderate atrophy on the left and moderate atrophy on the right), inf. temporal gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), sup. temporal gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), planum temporale (normal-to-mild atrophy on the left and mild atrophy on the right), transverse temporal gyrus (mild atrophy on the left), fusiform gyrus (normal on the left and mild atrophy on the right) and middle temporal gyrus (normal on the left and mild atrophy on the right) - mild-to-moderate bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: entorhinal area (mild-to-moderate atrophy both left/right), parahippocampal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right) and posterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) - occipital lobe maintains a normal appearance with no observable atrophic features - no evident atrophy or tissue thinning seen in the frontal lobe - mild bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: posterior insula (mild-to-moderate atrophy on the left and moderate-to-severe atrophy on the right) and anterior insula (mild atrophy on the left and mild-to-moderate atrophy on the right) - no appreciable degenerative or atrophic changes observed in the parietal lobe
BV
FTLD_203469454_01456_MR_Sagittal_MP-Rage_br_raw_20230206172857063_I10182094
On a T1-weighted brain MRI we observed: For the cerebral cortex: - frontal lobe appears within normal limits without apparent atrophy - no evident atrophy or tissue thinning seen in the parietal lobe - no findings suggestive of atrophy are seen in the occipital lobe - mild-to-moderate atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild-to-moderate atrophy on the left), entorhinal area (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), middle cingulate gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right) and parahippocampal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) - mild atrophy of the left insular cortex and mild-to-moderate atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and mild-to-moderate atrophy on the right) and central operculum (mild atrophy both left/right) - mild-to-moderate atrophy of the left temporal lobe and moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: inf. temporal gyrus (mild atrophy on the left and moderate atrophy on the right), middle temporal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right) and temporal pole (normal-to-mild atrophy on the left and mild atrophy on the right) For the ventricles: - moderate-to-severe bilateral enlargement of the inf. lateral ventricle - 4th ventricle appears to be of normal dimensions, with no observable increase in size - mild enlargement of the left lateral ventricle; normal-to-mild enlargement of the right lateral ventricle - mild-to-moderate enlargement of the 3rd ventricle - no clear enlargement or abnormal growth seen in the external csf For the subcortical structures: - no observable atrophic changes in the ventral dc - mild bilateral atrophy of the accumbens - no appreciable degenerative or atrophic changes observed in the thalamus - basal forebrain maintains a normal appearance with no observable atrophic features - moderate atrophy of the left hippocampus - mild-to-moderate atrophy of the right hippocampus - mild bilateral atrophy of the putamen - no findings suggestive of atrophy are seen in the pallidum - moderate-to-severe bilateral atrophy of the amygdala - no clear atrophic alterations are visible in the caudate
SV
FTLD_203773746_03647_MR_Accelerated_Sagittal_MPRAGE_br_raw_20241_I11047639
On a T1-weighted brain MRI we observed: For the cerebral cortex: - parietal lobe appears preserved, with no observable tissue loss - mild atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and normal-to-mild atrophy on the right) - mild atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: middle temporal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right) and planum polare (normal on the left and mild atrophy on the right) - mild atrophy of the right limbic cortex; normal-to-mild atrophy of the left limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and parahippocampal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) - no evident atrophy or tissue thinning seen in the occipital lobe - mild-to-moderate bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: gyrus rectus (mild atrophy on the left and normal-to-mild atrophy on the right), middle frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), precentral gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), orbital inf. frontal gyrus (mild atrophy on the left and normal on the right), lateral orbital gyrus (normal on the left and mild atrophy on the right), anterior orbital gyrus (mild atrophy on the left) and sup. frontal gyrus (mild atrophy on the left and normal on the right) For the ventricles: - moderate enlargement of the external csf - no findings suggestive of enlargement are seen in the 4th ventricle - no appreciable enlargement noted in the 3rd ventricle - no evident size increase noted in the lateral ventricle - no findings suggestive of enlargement are seen in the inf. lateral ventricle For the subcortical structures: - mild-to-moderate atrophy of the left amygdala and mild atrophy of the right amygdala - ventral dc maintains a normal appearance with no observable atrophic features - basal forebrain appears within normal limits without apparent atrophy - putamen maintains a normal appearance with no observable atrophic features - no findings suggestive of atrophy are seen in the thalamus - hippocampus demonstrates a healthy morphology without signs of atrophy - accumbens appears preserved, with no observable tissue loss - mild-to-moderate bilateral atrophy of the caudate - mild atrophy of the right pallidum; normal-to-mild atrophy of the left pallidum
PNFA
FTLD_203929346_03642_MR_Accelerated_Sagittal_MPRAGE_br_raw_20241_I11047637
On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild-to-moderate atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (mild-to-moderate atrophy on the left and moderate atrophy on the right), anterior cingulate gyrus (mild atrophy on the right) and parahippocampal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) - no evident atrophy or tissue thinning seen in the occipital lobe - frontal lobe appears preserved, with no observable tissue loss - severe atrophy of the right temporal lobe; the left temporal lobe is normal; focal volume loss observed in the following subregions: temporal pole (mild-to-moderate atrophy on the left and moderate-to-severe atrophy on the right), inf. temporal gyrus (normal-to-mild atrophy on the left and moderate-to-severe atrophy on the right), fusiform gyrus (normal-to-mild atrophy on the left and moderate atrophy on the right), middle temporal gyrus (moderate-to-severe atrophy on the right), sup. temporal gyrus (mild atrophy on the right) and planum polare (mild atrophy on the right) - parietal lobe appears preserved, with no observable tissue loss - mild atrophy of the right insular cortex; the left insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (mild-to-moderate atrophy on the right) and posterior insula (mild-to-moderate atrophy on the right) For the ventricles: - 4th ventricle maintains a typical volume without observable enlargement - mild enlargement of the left lateral ventricle and mild-to-moderate enlargement of the right lateral ventricle - mild enlargement of the left inf. lateral ventricle and severe enlargement of the right inf. lateral ventricle - mild enlargement of the external csf - mild enlargement of the 3rd ventricle For the subcortical structures: - mild atrophy of the right ventral dc; the left ventral dc is normal - moderate-to-severe atrophy of the left amygdala and severe atrophy of the right amygdala - no evident atrophy or tissue thinning seen in the basal forebrain - mild atrophy of the right thalamus; the left thalamus is normal - the left hippocampus volume is borderline low - moderate atrophy of the right hippocampus - mild atrophy of the left pallidum and moderate atrophy of the right pallidum - mild-to-moderate bilateral atrophy of the accumbens - moderate atrophy of the right putamen; normal-to-mild atrophy of the left putamen - mild atrophy of the right caudate; normal-to-mild atrophy of the left caudate
SV
FTLD_203885673_02378_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177207
On a T1-weighted brain MRI we observed: For the cerebral cortex: - occipital lobe demonstrates a healthy morphology without signs of atrophy - frontal lobe appears preserved, with no observable tissue loss - mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (moderate atrophy on the left and mild atrophy on the right) and parahippocampal gyrus (mild atrophy both left/right) - mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and mild atrophy on the right) and posterior insula (mild atrophy on the left and normal-to-mild atrophy on the right) - parietal lobe demonstrates a healthy morphology without signs of atrophy - severe atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy on the left and moderate atrophy on the right), planum polare (mild atrophy both left/right), middle temporal gyrus (mild-to-moderate atrophy on the left and normal on the right), fusiform gyrus (mild-to-moderate atrophy on the left) and inf. temporal gyrus (mild atrophy on the left and normal on the right) For the ventricles: - the 3rd ventricle shows no notable changes suggestive of enlargement - no observable enlargement of the 4th ventricle - no evident size increase noted in the external csf - mild-to-moderate enlargement of the left lateral ventricle; the right lateral ventricle is normal - severe enlargement of the left inf. lateral ventricle and mild-to-moderate enlargement of the right inf. lateral ventricle For the subcortical structures: - no appreciable degenerative or atrophic changes observed in the basal forebrain - moderate atrophy of the left hippocampus - the left hippocampus volume is borderline low - mild atrophy of the left pallidum; normal-to-mild atrophy of the right pallidum - caudate demonstrates a healthy morphology without signs of atrophy - severe atrophy of the left amygdala and moderate atrophy of the right amygdala - no clear atrophic alterations are visible in the thalamus - mild-to-moderate atrophy of the left putamen; the right putamen is normal - ventral dc demonstrates a healthy morphology without signs of atrophy - mild-to-moderate atrophy of the left accumbens and mild atrophy of the right accumbens
SV
ADNI_381_S_10536_MR_Accelerated_Sagittal_MPRAGE_MSV21_br_raw_20250325162210538_1_I11165365
On a T1-weighted brain MRI we observed: For the subcortical structures: - ventral dc appears within normal limits without apparent atrophy - no appreciable degenerative or atrophic changes observed in the caudate - no appreciable degenerative or atrophic changes observed in the basal forebrain - putamen appears within normal limits without apparent atrophy - pallidum maintains a normal appearance with no observable atrophic features - the left hippocampus volume is borderline low - no observable atrophic changes in the thalamus - amygdala demonstrates a healthy morphology without signs of atrophy - accumbens appears preserved, with no observable tissue loss For the ventricles: - external csf maintains a typical volume without observable enlargement - mild enlargement of the right inf. lateral ventricle; the left inf. lateral ventricle is normal - the 4th ventricle shows no notable changes suggestive of enlargement - 3rd ventricle maintains its expected proportions without signs of enlargement - no findings suggestive of enlargement are seen in the lateral ventricle For the cerebral cortex: - no findings suggestive of atrophy are seen in the limbic cortex - mild bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: inf. temporal gyrus (mild-to-moderate atrophy on the left and moderate atrophy on the right), middle temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and temporal pole (normal on the left and mild atrophy on the right) - mild atrophy of the left parietal lobe; the right parietal lobe is normal; focal volume loss observed in the following subregions: sup. parietal lobule (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) - occipital lobe maintains a normal appearance with no observable atrophic features - no appreciable degenerative or atrophic changes observed in the insular cortex - no findings suggestive of atrophy are seen in the frontal lobe
CN
ADNI_014_S_10409_MR_Accelerated_Sagittal_MPRAGE_MSV21_br_raw_20250218185310963_1_I11121641
On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild bilateral atrophy of the occipital lobe; focal volume loss observed in the following subregions: calcarine cortex (mild-to-moderate atrophy both left/right), middle occipital gyrus (mild-to-moderate atrophy on the right) and lingual gyrus (mild atrophy on the left and normal on the right) - mild atrophy of the left parietal lobe; the right parietal lobe is normal; focal volume loss observed in the following subregions: supramarginal gyrus (mild-to-moderate atrophy both left/right) and precuneus (mild atrophy on the left and normal on the right) - mild atrophy of the right insular cortex; normal-to-mild atrophy of the left insular cortex; focal volume loss observed in the following subregions: anterior insula (mild atrophy both left/right) and posterior insula (mild atrophy on the left and normal-to-mild atrophy on the right) - no findings suggestive of atrophy are seen in the temporal lobe - no findings suggestive of atrophy are seen in the limbic cortex - frontal lobe appears preserved, with no observable tissue loss For the subcortical structures: - no evident atrophy or tissue thinning seen in the basal forebrain - no clear atrophic alterations are visible in the hippocampus - no observable atrophic changes in the putamen - no evident atrophy or tissue thinning seen in the pallidum - no observable atrophic changes in the accumbens - the caudate shows no notable changes suggestive of atrophy - no findings suggestive of atrophy are seen in the thalamus - amygdala appears preserved, with no observable tissue loss - ventral dc appears preserved, with no observable tissue loss For the ventricles: - no evident size increase noted in the 3rd ventricle - mild enlargement of the external csf - the inf. lateral ventricle shows no notable changes suggestive of enlargement - 4th ventricle maintains its expected proportions without signs of enlargement - lateral ventricle appears to be of normal dimensions, with no observable increase in size
CN
ADNI_053_S_7086_MR_Accelerated_Sagittal_MPRAGE_MSV21_br_raw_20250630191515496_1_I11332562
On a T1-weighted brain MRI we observed: For the ventricles: - moderate-to-severe enlargement of the left inf. lateral ventricle and severe enlargement of the right inf. lateral ventricle - external csf maintains its expected proportions without signs of enlargement - 4th ventricle maintains a typical volume without observable enlargement - the 3rd ventricle shows no notable changes suggestive of enlargement - mild-to-moderate enlargement of the left lateral ventricle and moderate enlargement of the right lateral ventricle For the cerebral cortex: - mild atrophy of the right parietal lobe; normal-to-mild atrophy of the left parietal lobe; focal volume loss observed in the following subregions: angular gyrus (normal on the left and mild-to-moderate atrophy on the right) and precuneus (normal on the left and mild atrophy on the right) - no findings suggestive of atrophy are seen in the insular cortex - mild-to-moderate atrophy of the right temporal lobe; normal-to-mild atrophy of the left temporal lobe; focal volume loss observed in the following subregions: fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. temporal gyrus (normal on the left and mild atrophy on the right), inf. temporal gyrus (normal on the left and mild atrophy on the right) and middle temporal gyrus (mild atrophy on the right) - occipital lobe appears within normal limits without apparent atrophy - limbic cortex demonstrates a healthy morphology without signs of atrophy - no findings suggestive of atrophy are seen in the frontal lobe For the subcortical structures: - no appreciable degenerative or atrophic changes observed in the caudate - mild atrophy of the left amygdala and moderate atrophy of the right amygdala - mild atrophy of the right accumbens; normal-to-mild atrophy of the left accumbens - mild bilateral atrophy of the pallidum - the basal forebrain shows no notable changes suggestive of atrophy - mild atrophy of the right ventral dc; the left ventral dc is normal - mild bilateral atrophy of the putamen - mild atrophy of the right hippocampus - no findings suggestive of atrophy are seen in the thalamus
AD
ADNI_009_S_2381_MR_MPRAGE_GRAPPA2_br_raw_20130624101803453_158_S193107_I377789
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no evident atrophy or tissue thinning seen in the occipital lobe - mild atrophy of the left parietal lobe; normal-to-mild atrophy of the right parietal lobe - limbic cortex appears preserved, with no observable tissue loss - mild atrophy of the right insular cortex; the left insular cortex is normal; focal volume loss observed in the following subregions: parietal operculum (normal on the left and mild atrophy on the right) - temporal lobe maintains a normal appearance with no observable atrophic features - no appreciable degenerative or atrophic changes observed in the frontal lobe For the ventricles: - the lateral ventricle shows no notable changes suggestive of enlargement - no appreciable enlargement noted in the 3rd ventricle - mild-to-moderate enlargement of the external csf - no findings suggestive of enlargement are seen in the inf. lateral ventricle - no appreciable enlargement noted in the 4th ventricle For the subcortical structures: - moderate atrophy of the left hippocampus - moderate-to-severe atrophy of the right hippocampus - mild bilateral atrophy of the putamen - no appreciable degenerative or atrophic changes observed in the thalamus - mild-to-moderate atrophy of the left amygdala and moderate-to-severe atrophy of the right amygdala - pallidum appears preserved, with no observable tissue loss - accumbens maintains a normal appearance with no observable atrophic features - mild atrophy of the right ventral dc; the left ventral dc is normal - mild atrophy of the left caudate; normal-to-mild atrophy of the right caudate - no observable atrophic changes in the basal forebrain
AD
FTLD_203426391_02192_MR_Sagittal_MP-Rage_br_raw_20230209095858883_I10183320
On a T1-weighted brain MRI we observed: For the ventricles: - moderate enlargement of the external csf - 3rd ventricle appears within normal size limits with no apparent enlargement - no clear enlargement or abnormal growth seen in the inf. lateral ventricle - 4th ventricle maintains its expected proportions without signs of enlargement - no clear enlargement or abnormal growth seen in the lateral ventricle For the cerebral cortex: - mild bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: parahippocampal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), anterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and entorhinal area (mild atrophy on the left and normal on the right) - mild atrophy of the left parietal lobe and mild-to-moderate atrophy of the right parietal lobe; focal volume loss observed in the following subregions: precuneus (mild atrophy both left/right), sup. parietal lobule (mild atrophy both left/right) and supramarginal gyrus (mild atrophy on the right) - moderate atrophy of the left frontal lobe; normal-to-mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (mild atrophy both left/right), precentral gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. frontal gyrus (mild-to-moderate atrophy on the left and normal on the right), medial frontal cortex (normal on the left and mild atrophy on the right), supplementary motor cortex (mild atrophy on the left and normal on the right) and triangular inf. frontal gyrus (mild atrophy on the left) - the insular cortex shows no notable changes suggestive of atrophy - the temporal lobe shows no notable changes suggestive of atrophy - no appreciable degenerative or atrophic changes observed in the occipital lobe For the subcortical structures: - mild-to-moderate atrophy of the left amygdala; the right amygdala is normal - moderate atrophy of the left hippocampus - mild atrophy of the right hippocampus - mild atrophy of the left caudate; the right caudate is normal - no observable atrophic changes in the basal forebrain - no observable atrophic changes in the thalamus - the ventral dc shows no notable changes suggestive of atrophy - mild-to-moderate atrophy of the left putamen and mild atrophy of the right putamen - accumbens appears within normal limits without apparent atrophy - no observable atrophic changes in the pallidum
PNFA
FTLD_203236666_01663_MR_Sagittal_MP-Rage_br_raw_20230206173923274_I10182172
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild bilateral atrophy of the amygdala - the left hippocampus volume is borderline low - mild atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens - pallidum demonstrates a healthy morphology without signs of atrophy - mild-to-moderate atrophy of the left caudate and mild atrophy of the right caudate - mild-to-moderate atrophy of the left putamen and mild atrophy of the right putamen - no evident atrophy or tissue thinning seen in the ventral dc - mild atrophy of the left thalamus; the right thalamus is normal - basal forebrain demonstrates a healthy morphology without signs of atrophy For the ventricles: - moderate enlargement of the external csf - mild-to-moderate enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle - the 4th ventricle shows no notable changes suggestive of enlargement - mild enlargement of the right lateral ventricle; normal-to-mild enlargement of the left lateral ventricle - no appreciable enlargement noted in the 3rd ventricle For the cerebral cortex: - moderate atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: sup. temporal gyrus (moderate atrophy on the left and normal on the right), inf. temporal gyrus (mild atrophy on the left and normal on the right) and middle temporal gyrus (mild atrophy on the left and normal on the right) - mild-to-moderate atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and mild atrophy on the right), frontal operculum (mild atrophy both left/right) and parietal operculum (mild atrophy on the left) - moderate-to-severe atrophy of the left frontal lobe and mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), opercular inf. frontal gyrus (moderate atrophy on the left and mild atrophy on the right), sup. frontal gyrus medial segment (mild atrophy both left/right), medial orbital gyrus (mild atrophy on the left and normal on the right), sup. frontal gyrus (mild atrophy on the left and normal on the right) and lateral orbital gyrus (mild atrophy on the left) - no evident atrophy or tissue thinning seen in the occipital lobe - limbic cortex appears preserved, with no observable tissue loss - no observable atrophic changes in the parietal lobe
BV
FTLD_203697473_03379_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10450635
On a T1-weighted brain MRI we observed: For the ventricles: - moderate-to-severe enlargement of the external csf - mild-to-moderate enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal - moderate enlargement of the left lateral ventricle and mild enlargement of the right lateral ventricle - mild enlargement of the 3rd ventricle - no observable enlargement of the 4th ventricle For the subcortical structures: - ventral dc appears within normal limits without apparent atrophy - the left hippocampus volume is borderline low - mild atrophy of the right hippocampus - moderate atrophy of the left amygdala and severe atrophy of the right amygdala - mild-to-moderate atrophy of the left caudate and moderate atrophy of the right caudate - mild bilateral atrophy of the putamen - the pallidum shows no notable changes suggestive of atrophy - the basal forebrain shows no notable changes suggestive of atrophy - thalamus appears within normal limits without apparent atrophy - moderate atrophy of the left accumbens and mild atrophy of the right accumbens For the cerebral cortex: - mild atrophy of the right parietal lobe; the left parietal lobe is normal; focal volume loss observed in the following subregions: angular gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right) - moderate atrophy of the left frontal lobe and severe atrophy of the right frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (mild-to-moderate atrophy on the left and moderate-to-severe atrophy on the right), gyrus rectus (mild-to-moderate atrophy both left/right), sup. frontal gyrus medial segment (mild atrophy on the left and mild-to-moderate atrophy on the right), opercular inf. frontal gyrus (mild atrophy both left/right), medial frontal cortex (mild atrophy both left/right), sup. frontal gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), precentral gyrus (mild-to-moderate atrophy on the right), triangular inf. frontal gyrus (normal on the left and mild-to-moderate atrophy on the right), posterior orbital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and lateral orbital gyrus (normal on the left and mild atrophy on the right) - mild-to-moderate atrophy of the right temporal lobe; the left temporal lobe is normal; focal volume loss observed in the following subregions: sup. temporal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), temporal pole (normal-to-mild atrophy on the left and mild atrophy on the right), middle temporal gyrus (mild-to-moderate atrophy on the right), fusiform gyrus (normal on the left and mild atrophy on the right) and planum temporale (mild atrophy on the right) - the occipital lobe shows no notable changes suggestive of atrophy - moderate-to-severe bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: anterior insula (severe atrophy both left/right), posterior insula (mild-to-moderate atrophy both left/right), frontal operculum (mild atrophy both left/right), central operculum (mild atrophy on the left and normal-to-mild atrophy on the right) and parietal operculum (normal on the left and mild atrophy on the right) - mild bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild-to-moderate atrophy both left/right) and middle cingulate gyrus (mild atrophy on the left)
BV
ADNI_005_S_10288_MR_Accelerated_Sagittal_MPRAGE_MSV21_br_raw_20241022184200401_1_I10987612
On a T1-weighted brain MRI we observed: For the subcortical structures: - the accumbens shows no notable changes suggestive of atrophy - no observable atrophic changes in the basal forebrain - no clear atrophic alterations are visible in the caudate - thalamus demonstrates a healthy morphology without signs of atrophy - ventral dc demonstrates a healthy morphology without signs of atrophy - no evident atrophy or tissue thinning seen in the amygdala - no observable atrophic changes in the hippocampus - putamen maintains a normal appearance with no observable atrophic features - no findings suggestive of atrophy are seen in the pallidum For the cerebral cortex: - occipital lobe demonstrates a healthy morphology without signs of atrophy - the temporal lobe shows no notable changes suggestive of atrophy - frontal lobe appears within normal limits without apparent atrophy - no evident atrophy or tissue thinning seen in the insular cortex - mild atrophy of the right parietal lobe; normal-to-mild atrophy of the left parietal lobe; focal volume loss observed in the following subregions: angular gyrus (mild atrophy both left/right) - no observable atrophic changes in the limbic cortex For the ventricles: - inf. lateral ventricle maintains a typical volume without observable enlargement - no observable enlargement of the external csf - no findings suggestive of enlargement are seen in the lateral ventricle - 4th ventricle appears to be of normal dimensions, with no observable increase in size - 3rd ventricle appears to be of normal dimensions, with no observable increase in size
CN
FTLD_203349888_02884_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178251
On a T1-weighted brain MRI we observed: For the cerebral cortex: - occipital lobe demonstrates a healthy morphology without signs of atrophy - the frontal lobe shows no notable changes suggestive of atrophy - limbic cortex appears within normal limits without apparent atrophy - no observable atrophic changes in the insular cortex - mild bilateral atrophy of the parietal lobe; focal volume loss observed in the following subregions: angular gyrus (mild atrophy both left/right), precuneus (mild atrophy both left/right) and sup. parietal lobule (normal-to-mild atrophy on the left and mild atrophy on the right) - mild atrophy of the left temporal lobe; normal-to-mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: inf. temporal gyrus (mild atrophy both left/right) and fusiform gyrus (mild-to-moderate atrophy on the left and normal on the right) For the ventricles: - 3rd ventricle appears within normal size limits with no apparent enlargement - moderate-to-severe enlargement of the external csf - mild bilateral enlargement of the lateral ventricle - the inf. lateral ventricle shows no notable changes suggestive of enlargement - no evident size increase noted in the 4th ventricle For the subcortical structures: - caudate appears preserved, with no observable tissue loss - no evident atrophy or tissue thinning seen in the hippocampus - mild bilateral atrophy of the pallidum - mild-to-moderate atrophy of the left amygdala and mild atrophy of the right amygdala - the putamen shows no notable changes suggestive of atrophy - mild bilateral atrophy of the thalamus - the accumbens shows no notable changes suggestive of atrophy - mild bilateral atrophy of the ventral dc - no clear atrophic alterations are visible in the basal forebrain
CN
ADNI_027_S_1082_MR_MPR-R__GradWarp__B1_Correction__N3__Scaled_Br_20070327161431010_S22938_I47204
On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild atrophy of the right insular cortex; the left insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and mild-to-moderate atrophy on the right) and frontal operculum (mild atrophy both left/right) - mild atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: middle frontal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right) and sup. frontal gyrus medial segment (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) - mild atrophy of the left occipital lobe; the right occipital lobe is normal; focal volume loss observed in the following subregions: calcarine cortex (mild atrophy on the left and normal-to-mild atrophy on the right), occipital fusiform gyrus (mild-to-moderate atrophy on the left and normal on the right), middle occipital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and occipital pole (mild atrophy on the left and normal-to-mild atrophy on the right) - no evident atrophy or tissue thinning seen in the parietal lobe - mild bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: middle temporal gyrus (mild atrophy both left/right) and sup. temporal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) - limbic cortex appears within normal limits without apparent atrophy For the subcortical structures: - no appreciable degenerative or atrophic changes observed in the ventral dc - no appreciable degenerative or atrophic changes observed in the caudate - the thalamus shows no notable changes suggestive of atrophy - accumbens appears within normal limits without apparent atrophy - no findings suggestive of atrophy are seen in the pallidum - no evident atrophy or tissue thinning seen in the basal forebrain - moderate-to-severe bilateral atrophy of the amygdala - the putamen shows no notable changes suggestive of atrophy - mild atrophy of the left hippocampus - mild atrophy of the right hippocampus For the ventricles: - mild enlargement of the external csf - mild enlargement of the 3rd ventricle - mild bilateral enlargement of the lateral ventricle - 4th ventricle maintains a typical volume without observable enlargement - severe bilateral enlargement of the inf. lateral ventricle
AD