databio/diseases-msmarco · Datasets at Hugging Face

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What is autoimmune disease of central nervous system?	An autoimmune disease of the central nervous system.
What is leiomyoma?	A cell type benign neoplasm that is a benign tumor of smooth muscle cells.
What is human papillomavirus related adenocarcinoma?	A human papillomavirus related carcinoma that results_in infection, has_material_basis_in human papillomaviruses (types 16, 18, 31, 39 or 45), which cause lesions that progress to cancers.
What is essential tremor?	A movement disorder that causes involuntary tremors, especially in the hands. It occurs alone without other neurological signs and symptoms.
What is anal squamous cell carcinoma?	An anal carcinoma that arises near the squamocolumnar junction.
What is esotropia?	Esotropia is a strabismus in which the eye turns inward toward the nose.
What is basaloid squamous cell carcinoma?	A squamous cell carcinoma that has a solid, closely packed growth of cells with hyperchromatic nuclei, scant cytoplasm, small cystic spaces, and foci of necrosis. It has overlying squamous dysplasia, rare foci of overt keratinization, and/or coexistent keratinizing squamous cell carcinoma.
What is spleen cancer?	A lymphatic system cancer that affects white blood cells and involves tumor deposits in the spleen.
What is ectopic pregnancy?	A female reproductive system disease characterized by the implantation of the embryo outside the uterine cavity.
What is pneumococcal pneumonia?	A pneumococcal infectious disease that involves infection by the bacterium Streptococcus pneumoniae, also known as pneumococcus. In adults, pneumococcal pneumonia is often characterized by sudden onset of illness with symptoms including shaking chills, fever, shortness of breath or rapid breathing, pain in the chest that is worsened by breathing deeply, and a productive cough. In infants and young children, signs and symptoms may not be specific, and may include fever, cough, rapid breathing or grunting.
What is Fuchs' heterochromic uveitis?	A syndrome that is a chronic unilateral (or rarely bilateral) iridocyclitis appearing with the triad of heterochromia, predisposition to cataracts and glaucoma, and keratitic percipitates on the posterior corneal surface.
What is Microsporum fulvum tinea capitis?	An ectothrix infectious disease that results_in geophilic fungal infection located_in scalp and located_in hair in humans and animals, has_material_basis_in Microsporum fulvum.
What is (-)ssRNA virus infectious disease?	A RNA virus infectious disease that results_in infection, has_material_basis_in ssRNA negative-strand viruses, which have negative-sense single-stranded RNA genomes.
What is Plasmodium ovale malaria?	A malaria characaterized as a relatively mild form caused by a parasite Plasmodium ovale, which is characterized by tertian chills and febrile paroxysms, and that ends spontaneously.
What is chronic myeloproliferative disease?	A myeloma that is characterized by a group of slow growing blood cancers in which large numbers of abnormal red blood cells, white blood cells, or platelets grow and spread in the bone marrow and the peripheral blood.
What is placental insufficiency?	A placenta disease that is characterized by insufficient blood flow to the placenta during pregnancy.
What is articulation disorder?	A speech disorder that involves mispronouncing speech sounds by omitting, distorting, substituting, or adding sounds which can make speech difficult to understand.
What is angiosarcoma?	A malignant vascular tumor that results_in rapidly proliferating, extensively infiltrating anaplastic cells derived_from blood vessels and derived_from the lining of irregular blood-filled spaces.
What is poliomyelitis?	A viral infectious disease that results_in destruction located_in motor neurons, has_material_basis_in Human poliovirus 1, has_material_basis_in Human poliovirus 2, or has_material_basis_in Human poliovirus 3, which are transmitted_by ingestion of food or water contaminated with feces, or transmitted_by direct contact with the oral secretions. The infection has_symptom fever, has_symptom sore throat, has_symptom headache, has_symptom vomiting, has_symptom fatigue, has_symptom neck stiffness, has_symptom muscle spasms, and has_symptom acute flaccid paralysis.
What is lung giant cell carcinoma?	A lung carcinoma that is located_in large undifferentiated cells.
What is anisakiasis?	A parasitic helminthiasis infectious disease that results_in infection located_in intestinal mucosa with larvae of the nematodes transmitted_by ingestion of raw or poorly cooked saltwater fish, has_material_basis_in Anisakis simplex or has_material_basis_in Pseudoterranova decipiens and has_symptom abdominal pain, has_symptom nausea and vomiting. Invasive anisakiasis results in the infection of omentum, pancreas, liver, and lung.
What is alexithymia?	An agnosia that is a deficiency in understanding, processing, or describing emotions.
What is metaphyseal dysplasia?	An osteochondrodysplasia that results_in thinning and the tendency to fracture located_in bone.
What is gamma-amino butyric acid metabolism disorder?	An amino acid metabolic disorder characterized by impairment of the GABA catabolic pathway.
What is hypertension?	An artery disease characterized by chronic elevated blood pressure in the arteries.
What is amyotrophic lateral sclerosis type 4?	A type of ALS with juvenile onset caused_by mutation located_in senataxin gene (SETX) located_in chromosome 9.
What is Johanson-Blizzard syndrome?	An autosomal recessive disease that involves abnormal development of the pancreas, nose and scalp, with mental retardation, hearing loss and growth failure. It is inherited in an autosomal recessive manner.
What is variola minor?	A smallpox that results_in milder infection, located_in skin, has_material_basis_in Variola virus. The infection results_in_formation_of lesions.
What is autosomal dominant nonsyndromic deafness?	A nonsyndromic deafness characterized by an autosomal dominant inheritance mode.
What is disease of cellular proliferation?	A disease that is characterized by abnormally rapid cell division.
What is lateral sclerosis?	A motor neuron disease characterized by painless but progressive weakness and stiffness of the muscles of the legs.
What is Chagas disease?	A trypanosomiasis that is a tropical parasitic disease caused by the flagellate protozoan Trypanosoma cruzi, which is transmitted to humans and other mammals by an insect vector, the blood-sucking assassin bugs of the subfamily Triatominae (family Reduviidae), most commonly species belonging to the Triatoma, Rhodnius, and Panstrongylus genera. The symptoms include fever, fatigue, body aches, headache, rash, loss of appetite, diarrhea, vomiting, swelling of the eyelids and myocarditis.
What is lymphatic system disease?	An immune system disease that is located_in the lymphatic system.
What is disease?	A disease is a disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism.
What is leiomyosarcoma?	A malignant smooth muscle cancer that can arise almost anywhere in the body, but is most common in the uterus, abdomen, or pelvis.
What is cerebral folate receptor alpha deficiency?	A vitamin metabolic disorder that has_material_basis_in mutations in the folate receptor 1 (FOLR1) gene coding for folate receptor alpha (FRalpha), is located_in the brain and is characterized by progressive movement disturbance, psychomotor decline, and epilepsy.
What is ischemia?	A vascular disease that is characterized by a restriction in blood supply to tissues.
What is asymptomatic neurosyphilis?	A tertiary neurosyphilis that results_in mild meningitis.
What is hereditary spastic paraplegia?	A paraplegia that is characterized by progressive stiffness and contraction (spasticity) in the lower limbs.
What is Ross River fever?	A viral infectious disease that results_in infection located_in joint, has_material_basis_in Ross River virus, which is transmitted_by Culex, and transmitted_by Aedes mosquitoes. The infection has_symptom fever, has_symptom arthralgia, and has_symptom rash.
What is methylmalonic acidemia?	An organic acidemia that involves an accumulation of methylmalonic acid in the blood.
What is Lyme disease?	A primary bacterial infectious disease that results_in infection, has_material_basis_in Borrelia burgdorferi, which is transmitted_by blacklegged tick (Ixodes scapularis) or transmitted_by western blacklegged tick (Ixodes pacificus). The infection has_symptom fever, has_symptom headache, has_symptom fatigue, and has_symptom skin rash called erythema migrans. If left untreated, infection can spread to joints, the heart, and the nervous system.
What is coccidiosis?	A parasitic protozoa infectious disease that occurs in the intestinal tract of animals and humans caused by Coccidia protozoa. Immunocompromised persons are at greater risk of developing the infection.
What is sarcocystosis?	A coccidiosis that involves infection of the intestine and muscles of humans and animals caused by an intracellular protozoan parasite of genus Sarcocystis. The symptoms include mild fever, diarrhea, chills, vomiting, muscle swelling, erythema, muscle tenderness,cough, arthralgia, transient pruritic rashes, headache, malaise and lymphadenopathy.
What is extragonadal nonseminomatous germ cell tumor?	An extragonadal germ cell cancer that are located_in the pineal gland in the brain, located_in the mediastinum or located_in the abdomen.
What is myotonic dystrophy type 1?	A myotonic disease that is characterized by progressive muscle wasting and weakness affecting the distal skeletal and smooth muscles of lower legs, hands, neck, and face along with myotonia and cataracts and has_physical_basis_in the autosomal dominant inheritance of the DMPK gene containing an expansion of a CTG trinucleotide repeat in the non-coding region.
What is Coxiella burnetii pneumonia?	A Q fever that is a zoonotic infectious disease caused by Coxiella burnetii, a bacterium which affects both humans and animals. The symptoms include fever, headache, cough, pleuritic chest pain, myalgia and arthralgia. Infection of humans usually occurs by inhalation of these organisms from air that contains airborne barnyard dust contaminated by dried placental material, birth fluids, or excreta of infected herd animals, ingestion of contaminated milk, tick bites and human to human transmission.
What is anus rhabdomyosarcoma?	A rhabdomyosarcoma and sarcoma of the anus that is located_in the anus.
What is obsessive-compulsive personality disorder?	A personality disorder that is characterized by a pervasive pattern of preoccupation with orderliness, perfectionism, and mental and interpersonal control at the expense of flexibility, openness, and efficiency.
What is achondrogenesis type II?	An achondrogenesis that has_material_basis_in mutations in the COL2A1 gene which results_in underdeveloped lungs, hydrops fetalis, a prominent forehead and abnormal ossification of the located_in vertebral column or located_in pelvis.
What is pulmonary alveolar proteinosis?	A lung disease that is characterized by abnormal accumulation of surfactant occurs within the alveoli, interfering with gas exchange.
What is megalocornea?	A corneal disease characterized by a bilaterally enlarged corneal diameter without an increase in intraocular pressure; caused_by mutation in the CHRDL1 gene.
What is human papilloma virus related anal squamous cell carcinoma?	A human papillomavirus related squamous cell carcinoma that results_in infection located_in anus, has_material_basis_in human papillomavirus (types 16 or 18), which cause malignant tumors in squamous epithelium of anus.
What is silicosis?	A pneumoconiosis that is an inflammation and scarring of the uper lobes of the lungs causing nodular lesions resulting from inhalation of silica, quartz or slate particles.
What is mediastinum liposarcoma?	A liposarcoma and mediastinum sarcoma that is located_in the mediastinum.
What is cholera?	A primary bacterial infectious disease that is described as an acute, diarrheal illness caused by infection of the intestine with the bacterium Vibrio cholerae, which is characterized by profuse watery diarrhea, vomiting, leg cramps, circulatory collapse and shock.
What is Measles virus hepatitis?	A Measles virus infectious disease that results_in inflammation located_in liver, has_material_basis_in Measles virus, which is transmitted_by contact with oronasal secretions, or semen of an infected person. The infection causes hepatic dysfunction and has_symptom jaundice.
What is metabolic acidosis?	A lactic acidosis that has_material_basis_in high levels of acid.
What is hallucinogen dependence?	A drug dependence that involves the continued use of hallucinogenic drugs despite problems related to use of the substance.
What is urea cycle disorder?	An amino acid metabolic disorder that involves a deficiency of one of the enzymes in the urea cycle which is responsible for removing ammonia from the blood stream.
What is central nervous system cancer?	A nervous system cancer that is located_in the central nervous system.
What is Capgras syndrome?	A delusional disorder in which a person holds a delusion that a friend, spouse, parent, or other close family member has been replaced by an identical-looking impostor.
What is bladder disease?	A urinary system disease that is located_in the bladder.
What is coccidioidal meningitis?	A coccidioidomycosis that results_in inflammation located_in meninges, has_material_basis_in Coccidioides immitis, transmitted_by airborne spores and has_symptom headache, has_symptom alterations in sensorium, and has_symptom obstructing hydrocephalus.
What is intraocular retinoblastoma?	A retinoblastoma that is located_in the eye and has not spread to other parts of the body.
What is somatization disorder?	A somatoform disorder that involves persistently complaints of varied physical symptoms that have no identifiable physical origin.
What is hepatobiliary disease?	A gastrointestinal system disease that is located_in the liver and/or biliary tract.
What is tongue squamous cell carcinoma?	A tongue cancer that is located_in the squamous cells of the tongue.
What is sennetsu fever?	A primary bacterial infectious disease that results_in infection, has_material_basis_in Neorickettsia sennetsu, which is transmitted_by ingestion of raw or under-cooked gray mullet fish infected with the trematodes. The infection has_symptom fever, has_symptom malaise, has_symptom anorexia, has_symptom lymphadenopathy, has_symptom hepatosplenomegaly, has_symptom fatigue, has_symptom chills, has_symptom headache, has_symptom backache and has_symptom myalgia.
What is squamous cell neoplasm?	A cell type benign neoplasm composed_of epithelial cells located_in the ectodermal or endodermal cells linking body cavities.
What is glandular tularemia?	A tularemia that results_in swelling of regional lymph glands.
What is skeletal tuberculosis?	An extrapulmonary tuberculosis that results in formation of lesions located_in bone.
What is familial hypercholesterolemia?	A familial hyperlipidemia characterized by very high levels of low-density lipoprotein (LDL) and early cardiovascular disease.
What is lung mucoepidermoid carcinoma?	A lung carcinoma that has_material_basis in a combination of squamous cells, mucus secreting cells and intermediate cells.
What is neuromyelitis optica?	A central nervous system disease characterized by acute neuritis located_in eye and demyelination located_in optic nerve and located_in spinal cord.
What is Trichophyton soudanense tinea capitis?	An endothrix infectious disease that results_in anthropophilic fungal infection located_in scalp and located_in hair, has_material_basis_in Trichophyton soudanense.
What is tuberculous empyema?	A pleural empyema which involves presence of pus in the pleural cavity and calcified visceral pleura. It results from a large number of mycobacteria spilling into the pleural space, usually from rupture of a cavity or an adjacent paranchymal focus via a bronchopleural fistula.
What is left ventricular noncompaction?	An intrinsic cardiomyopathy characterized by distinctive (spongy) morphological appearance of the LV myocardium.
What is mediastinum neuroblastoma?	A malignant mediastinal neurogenic neoplasm that has_material_basis_in immature nerve cells.
What is sialuria?	A lysosomal storage disease characterized by increased sialic acid in the urine.
What is herpes simplex?	A viral infectious disease that results_in_formation_of lesions, located_in mouth, located_in face, located_in genitalia, or located_in hands, has_material_basis_in Human herpesvirus 1 or has_material_basis_in Human herpesvirus 2, which are transmitted_by direct contact with an active lesion or body fluid of an infected person.
What is bilateral retinoblastoma?	A retinoblastoma that develops in both eyes.
What is trypanosomiasis?	A parasitic protozoa infectious disease that involves infection caused by parasitic protozoan of the genus Trypanosoma in animals and humans.
What is AIDS dementia complex?	A HIV encephalopathy that results_in infection in adults located_in brain, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2. The infection has_symptom cognitive impairment, has_symptom motor dysfunction, has_symptom behavioral change, and has_symptom speech problems.
What is visna?	A viral infectious disease that results_in infection located_in brain in sheep and goats, has_material_basis_in Visna/Maedi virus , which is transmitted_by droplet spread of oronasal secretion, and transmitted_by ingestion of contaminated water, milk or colostrum. The infection has_symptom hindlimb weakness, has_symptom head tilt, has_symptom ataxia, has_symptom incoordination, has_symptom muscle tremors, has_symptom paresis, and has_symptom paraplegia.
What is subleukemic leukemia?	A leukemia that is characterized by the presence of abnormal white blood cells located_in peripheral blood, but in which the total number of white blood cells is normal.
What is bubonic plague?	A plague that results_in infection located_in lymph node producing a bubo, which is an inflamed, necrotic, and hemorrhagic lymphoid tissue. The infection has_symptom enlarged, tender lymph nodes, has_symptom fever, has_symptom chills and has_symptom prostration.
What is disseminated paracoccidioidomycosis?	A primary systemic mycosis that results_in systemic fungal infection through hematogenous spread, has_material_basis_in Paracoccidioides brasiliensis.
What is thoracic disease?	A disease of anatomical entity that is located_in the thoracic cavity.
What is complex genetic disease?	A genetic disease that require multiple abnormal alleles to manifest are complex. These diseases are termed multifactorial or polygenic. Expressivity or penetrance of the disease is complex and is associated with multiple genes in combination with lifestyle and environmental factors. Multifactoral genetic diseases include heart disease and diabetes, although a subset of diabetes may be classified as a monogenic disease (due to the presence of a single abnormal allele).
What is leukemia?	A cancer that affects the blood or bone marrow characterized by an abnormal proliferation of blood cells.
What is myeloid metaplasia?	A myeloma and spenic disease that is located_in the bone marrow that results_in the marrow being replaced by fibrous (scar) tissue and has_symptom abdominal fullness related to an enlarged spleen, has_symptom bone pain, has_symptom bruising, has_symptom easy bleeding, has_symptom fatigue, has_symptom increased susceptibility to infection, has_symptom pallor, has_symtom shortness of breath while doing physical work.
What is cervical dystonia?	A focal dystonia that is characterized by simultaneous contraction of the agonist and antagonist muscles that control the position of the head contracting during dystonic movement which causes the neck to involuntarily turn to the left, right, upwards, and/or downwards.
What is Townes-Brocks syndrome?	An autosomal dominant disease that is characterized by imperforate anus, dysplastic ears often associated with sensorineural and/or conductive hearing impairment, and thumb malformations.
What is pseudoachondroplasia?	An osteochondrodysplasia that has_material_basis_in mutations in the COMP gene which results_in short limb dwarfism.
What is bilirubin metabolic disorder?	An inherited metabolic disorder that involves elevated levels of bilirubin resulting from disruption of bilirubin metabolism.
What is mucopolysaccharidosis I?	A mucopolysaccharidosis characterized by a deficiency of the lysosomal enzyme alpha-L-iduronidase.
What is pulmonary paracoccidioidomycosis?	A primary systemic mycosis that results_in inflammation located_in lungs, has_material_basis_in Paracoccidioides brasiliensis and has_symptom cough, has_symptom fever, has_symptom night sweats, has_symptom malaise, and has_symptom weight loss.
What is papillary adenocarcinoma?	An adenocarcinoma that derives_from epithelial cells originating in glandular tissue, which form complex papillary structures and exhibit compressive, destructive growth that replaces the normal tissue.
What is fusariosis?	An opportunistic mycosis that involves localized or hematogenously disseminated fungal infection by Fusarium solani or Fusarium oxysporum. Skin lesions are seen in neutropenic patients, and indolent cellulitis or soft-tissue necrosis occur in immunocompromised patients at the site of trauma.

What is autoimmune disease of central nervous system?

An autoimmune disease of the central nervous system.

What is leiomyoma?

A cell type benign neoplasm that is a benign tumor of smooth muscle cells.

What is human papillomavirus related adenocarcinoma?

A human papillomavirus related carcinoma that results_in infection, has_material_basis_in human papillomaviruses (types 16, 18, 31, 39 or 45), which cause lesions that progress to cancers.

What is essential tremor?

A movement disorder that causes involuntary tremors, especially in the hands. It occurs alone without other neurological signs and symptoms.

What is anal squamous cell carcinoma?

An anal carcinoma that arises near the squamocolumnar junction.

What is esotropia?

Esotropia is a strabismus in which the eye turns inward toward the nose.

What is basaloid squamous cell carcinoma?

A squamous cell carcinoma that has a solid, closely packed growth of cells with hyperchromatic nuclei, scant cytoplasm, small cystic spaces, and foci of necrosis. It has overlying squamous dysplasia, rare foci of overt keratinization, and/or coexistent keratinizing squamous cell carcinoma.

What is spleen cancer?

A lymphatic system cancer that affects white blood cells and involves tumor deposits in the spleen.

What is ectopic pregnancy?

A female reproductive system disease characterized by the implantation of the embryo outside the uterine cavity.

What is pneumococcal pneumonia?

A pneumococcal infectious disease that involves infection by the bacterium Streptococcus pneumoniae, also known as pneumococcus. In adults, pneumococcal pneumonia is often characterized by sudden onset of illness with symptoms including shaking chills, fever, shortness of breath or rapid breathing, pain in the chest that is worsened by breathing deeply, and a productive cough. In infants and young children, signs and symptoms may not be specific, and may include fever, cough, rapid breathing or grunting.

What is Fuchs' heterochromic uveitis?

A syndrome that is a chronic unilateral (or rarely bilateral) iridocyclitis appearing with the triad of heterochromia, predisposition to cataracts and glaucoma, and keratitic percipitates on the posterior corneal surface.

What is Microsporum fulvum tinea capitis?

An ectothrix infectious disease that results_in geophilic fungal infection located_in scalp and located_in hair in humans and animals, has_material_basis_in Microsporum fulvum.

What is (-)ssRNA virus infectious disease?

A RNA virus infectious disease that results_in infection, has_material_basis_in ssRNA negative-strand viruses, which have negative-sense single-stranded RNA genomes.

What is Plasmodium ovale malaria?

A malaria characaterized as a relatively mild form caused by a parasite Plasmodium ovale, which is characterized by tertian chills and febrile paroxysms, and that ends spontaneously.

What is chronic myeloproliferative disease?

A myeloma that is characterized by a group of slow growing blood cancers in which large numbers of abnormal red blood cells, white blood cells, or platelets grow and spread in the bone marrow and the peripheral blood.

What is placental insufficiency?

A placenta disease that is characterized by insufficient blood flow to the placenta during pregnancy.

What is articulation disorder?

A speech disorder that involves mispronouncing speech sounds by omitting, distorting, substituting, or adding sounds which can make speech difficult to understand.

What is angiosarcoma?

A malignant vascular tumor that results_in rapidly proliferating, extensively infiltrating anaplastic cells derived_from blood vessels and derived_from the lining of irregular blood-filled spaces.

What is poliomyelitis?

A viral infectious disease that results_in destruction located_in motor neurons, has_material_basis_in Human poliovirus 1, has_material_basis_in Human poliovirus 2, or has_material_basis_in Human poliovirus 3, which are transmitted_by ingestion of food or water contaminated with feces, or transmitted_by direct contact with the oral secretions. The infection has_symptom fever, has_symptom sore throat, has_symptom headache, has_symptom vomiting, has_symptom fatigue, has_symptom neck stiffness, has_symptom muscle spasms, and has_symptom acute flaccid paralysis.

What is lung giant cell carcinoma?

A lung carcinoma that is located_in large undifferentiated cells.

What is anisakiasis?

A parasitic helminthiasis infectious disease that results_in infection located_in intestinal mucosa with larvae of the nematodes transmitted_by ingestion of raw or poorly cooked saltwater fish, has_material_basis_in Anisakis simplex or has_material_basis_in Pseudoterranova decipiens and has_symptom abdominal pain, has_symptom nausea and vomiting. Invasive anisakiasis results in the infection of omentum, pancreas, liver, and lung.

What is alexithymia?

An agnosia that is a deficiency in understanding, processing, or describing emotions.

What is metaphyseal dysplasia?

An osteochondrodysplasia that results_in thinning and the tendency to fracture located_in bone.

What is gamma-amino butyric acid metabolism disorder?

An amino acid metabolic disorder characterized by impairment of the GABA catabolic pathway.

What is hypertension?

An artery disease characterized by chronic elevated blood pressure in the arteries.

What is amyotrophic lateral sclerosis type 4?

A type of ALS with juvenile onset caused_by mutation located_in senataxin gene (SETX) located_in chromosome 9.

What is Johanson-Blizzard syndrome?

An autosomal recessive disease that involves abnormal development of the pancreas, nose and scalp, with mental retardation, hearing loss and growth failure. It is inherited in an autosomal recessive manner.

What is variola minor?

A smallpox that results_in milder infection, located_in skin, has_material_basis_in Variola virus. The infection results_in_formation_of lesions.

What is autosomal dominant nonsyndromic deafness?

A nonsyndromic deafness characterized by an autosomal dominant inheritance mode.

What is disease of cellular proliferation?

A disease that is characterized by abnormally rapid cell division.

What is lateral sclerosis?

A motor neuron disease characterized by painless but progressive weakness and stiffness of the muscles of the legs.

What is Chagas disease?

A trypanosomiasis that is a tropical parasitic disease caused by the flagellate protozoan Trypanosoma cruzi, which is transmitted to humans and other mammals by an insect vector, the blood-sucking assassin bugs of the subfamily Triatominae (family Reduviidae), most commonly species belonging to the Triatoma, Rhodnius, and Panstrongylus genera. The symptoms include fever, fatigue, body aches, headache, rash, loss of appetite, diarrhea, vomiting, swelling of the eyelids and myocarditis.

What is lymphatic system disease?

An immune system disease that is located_in the lymphatic system.

What is disease?

A disease is a disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism.

What is leiomyosarcoma?

A malignant smooth muscle cancer that can arise almost anywhere in the body, but is most common in the uterus, abdomen, or pelvis.

What is cerebral folate receptor alpha deficiency?

A vitamin metabolic disorder that has_material_basis_in mutations in the folate receptor 1 (FOLR1) gene coding for folate receptor alpha (FRalpha), is located_in the brain and is characterized by progressive movement disturbance, psychomotor decline, and epilepsy.

What is ischemia?

A vascular disease that is characterized by a restriction in blood supply to tissues.

What is asymptomatic neurosyphilis?

A tertiary neurosyphilis that results_in mild meningitis.

What is hereditary spastic paraplegia?

A paraplegia that is characterized by progressive stiffness and contraction (spasticity) in the lower limbs.

What is Ross River fever?

A viral infectious disease that results_in infection located_in joint, has_material_basis_in Ross River virus, which is transmitted_by Culex, and transmitted_by Aedes mosquitoes. The infection has_symptom fever, has_symptom arthralgia, and has_symptom rash.

What is methylmalonic acidemia?

An organic acidemia that involves an accumulation of methylmalonic acid in the blood.

What is Lyme disease?

A primary bacterial infectious disease that results_in infection, has_material_basis_in Borrelia burgdorferi, which is transmitted_by blacklegged tick (Ixodes scapularis) or transmitted_by western blacklegged tick (Ixodes pacificus). The infection has_symptom fever, has_symptom headache, has_symptom fatigue, and has_symptom skin rash called erythema migrans. If left untreated, infection can spread to joints, the heart, and the nervous system.

What is coccidiosis?

A parasitic protozoa infectious disease that occurs in the intestinal tract of animals and humans caused by Coccidia protozoa. Immunocompromised persons are at greater risk of developing the infection.

What is sarcocystosis?

A coccidiosis that involves infection of the intestine and muscles of humans and animals caused by an intracellular protozoan parasite of genus Sarcocystis. The symptoms include mild fever, diarrhea, chills, vomiting, muscle swelling, erythema, muscle tenderness,cough, arthralgia, transient pruritic rashes, headache, malaise and lymphadenopathy.

What is extragonadal nonseminomatous germ cell tumor?

An extragonadal germ cell cancer that are located_in the pineal gland in the brain, located_in the mediastinum or located_in the abdomen.

What is myotonic dystrophy type 1?

A myotonic disease that is characterized by progressive muscle wasting and weakness affecting the distal skeletal and smooth muscles of lower legs, hands, neck, and face along with myotonia and cataracts and has_physical_basis_in the autosomal dominant inheritance of the DMPK gene containing an expansion of a CTG trinucleotide repeat in the non-coding region.

What is Coxiella burnetii pneumonia?

A Q fever that is a zoonotic infectious disease caused by Coxiella burnetii, a bacterium which affects both humans and animals. The symptoms include fever, headache, cough, pleuritic chest pain, myalgia and arthralgia. Infection of humans usually occurs by inhalation of these organisms from air that contains airborne barnyard dust contaminated by dried placental material, birth fluids, or excreta of infected herd animals, ingestion of contaminated milk, tick bites and human to human transmission.

What is anus rhabdomyosarcoma?

A rhabdomyosarcoma and sarcoma of the anus that is located_in the anus.

What is obsessive-compulsive personality disorder?

A personality disorder that is characterized by a pervasive pattern of preoccupation with orderliness, perfectionism, and mental and interpersonal control at the expense of flexibility, openness, and efficiency.

What is achondrogenesis type II?

An achondrogenesis that has_material_basis_in mutations in the COL2A1 gene which results_in underdeveloped lungs, hydrops fetalis, a prominent forehead and abnormal ossification of the located_in vertebral column or located_in pelvis.

What is pulmonary alveolar proteinosis?

A lung disease that is characterized by abnormal accumulation of surfactant occurs within the alveoli, interfering with gas exchange.

What is megalocornea?

A corneal disease characterized by a bilaterally enlarged corneal diameter without an increase in intraocular pressure; caused_by mutation in the CHRDL1 gene.

What is human papilloma virus related anal squamous cell carcinoma?

A human papillomavirus related squamous cell carcinoma that results_in infection located_in anus, has_material_basis_in human papillomavirus (types 16 or 18), which cause malignant tumors in squamous epithelium of anus.

What is silicosis?

A pneumoconiosis that is an inflammation and scarring of the uper lobes of the lungs causing nodular lesions resulting from inhalation of silica, quartz or slate particles.

What is mediastinum liposarcoma?

A liposarcoma and mediastinum sarcoma that is located_in the mediastinum.

What is cholera?

A primary bacterial infectious disease that is described as an acute, diarrheal illness caused by infection of the intestine with the bacterium Vibrio cholerae, which is characterized by profuse watery diarrhea, vomiting, leg cramps, circulatory collapse and shock.

What is Measles virus hepatitis?

A Measles virus infectious disease that results_in inflammation located_in liver, has_material_basis_in Measles virus, which is transmitted_by contact with oronasal secretions, or semen of an infected person. The infection causes hepatic dysfunction and has_symptom jaundice.

What is metabolic acidosis?

A lactic acidosis that has_material_basis_in high levels of acid.

What is hallucinogen dependence?

A drug dependence that involves the continued use of hallucinogenic drugs despite problems related to use of the substance.

What is urea cycle disorder?

An amino acid metabolic disorder that involves a deficiency of one of the enzymes in the urea cycle which is responsible for removing ammonia from the blood stream.

What is central nervous system cancer?

A nervous system cancer that is located_in the central nervous system.

What is Capgras syndrome?

A delusional disorder in which a person holds a delusion that a friend, spouse, parent, or other close family member has been replaced by an identical-looking impostor.

What is bladder disease?

A urinary system disease that is located_in the bladder.

What is coccidioidal meningitis?

A coccidioidomycosis that results_in inflammation located_in meninges, has_material_basis_in Coccidioides immitis, transmitted_by airborne spores and has_symptom headache, has_symptom alterations in sensorium, and has_symptom obstructing hydrocephalus.

What is intraocular retinoblastoma?

A retinoblastoma that is located_in the eye and has not spread to other parts of the body.

What is somatization disorder?

A somatoform disorder that involves persistently complaints of varied physical symptoms that have no identifiable physical origin.

What is hepatobiliary disease?

A gastrointestinal system disease that is located_in the liver and/or biliary tract.

What is tongue squamous cell carcinoma?

A tongue cancer that is located_in the squamous cells of the tongue.

What is sennetsu fever?

A primary bacterial infectious disease that results_in infection, has_material_basis_in Neorickettsia sennetsu, which is transmitted_by ingestion of raw or under-cooked gray mullet fish infected with the trematodes. The infection has_symptom fever, has_symptom malaise, has_symptom anorexia, has_symptom lymphadenopathy, has_symptom hepatosplenomegaly, has_symptom fatigue, has_symptom chills, has_symptom headache, has_symptom backache and has_symptom myalgia.

What is squamous cell neoplasm?

A cell type benign neoplasm composed_of epithelial cells located_in the ectodermal or endodermal cells linking body cavities.

What is glandular tularemia?

A tularemia that results_in swelling of regional lymph glands.

What is skeletal tuberculosis?

An extrapulmonary tuberculosis that results in formation of lesions located_in bone.

What is familial hypercholesterolemia?

A familial hyperlipidemia characterized by very high levels of low-density lipoprotein (LDL) and early cardiovascular disease.

What is lung mucoepidermoid carcinoma?

A lung carcinoma that has_material_basis in a combination of squamous cells, mucus secreting cells and intermediate cells.

What is neuromyelitis optica?

A central nervous system disease characterized by acute neuritis located_in eye and demyelination located_in optic nerve and located_in spinal cord.

What is Trichophyton soudanense tinea capitis?

An endothrix infectious disease that results_in anthropophilic fungal infection located_in scalp and located_in hair, has_material_basis_in Trichophyton soudanense.

What is tuberculous empyema?

A pleural empyema which involves presence of pus in the pleural cavity and calcified visceral pleura. It results from a large number of mycobacteria spilling into the pleural space, usually from rupture of a cavity or an adjacent paranchymal focus via a bronchopleural fistula.

What is left ventricular noncompaction?

An intrinsic cardiomyopathy characterized by distinctive (spongy) morphological appearance of the LV myocardium.

What is mediastinum neuroblastoma?

A malignant mediastinal neurogenic neoplasm that has_material_basis_in immature nerve cells.

What is sialuria?

A lysosomal storage disease characterized by increased sialic acid in the urine.

What is herpes simplex?

A viral infectious disease that results_in_formation_of lesions, located_in mouth, located_in face, located_in genitalia, or located_in hands, has_material_basis_in Human herpesvirus 1 or has_material_basis_in Human herpesvirus 2, which are transmitted_by direct contact with an active lesion or body fluid of an infected person.

What is bilateral retinoblastoma?

A retinoblastoma that develops in both eyes.

What is trypanosomiasis?

A parasitic protozoa infectious disease that involves infection caused by parasitic protozoan of the genus Trypanosoma in animals and humans.

What is AIDS dementia complex?

A HIV encephalopathy that results_in infection in adults located_in brain, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2. The infection has_symptom cognitive impairment, has_symptom motor dysfunction, has_symptom behavioral change, and has_symptom speech problems.

What is visna?

A viral infectious disease that results_in infection located_in brain in sheep and goats, has_material_basis_in Visna/Maedi virus , which is transmitted_by droplet spread of oronasal secretion, and transmitted_by ingestion of contaminated water, milk or colostrum. The infection has_symptom hindlimb weakness, has_symptom head tilt, has_symptom ataxia, has_symptom incoordination, has_symptom muscle tremors, has_symptom paresis, and has_symptom paraplegia.

What is subleukemic leukemia?

A leukemia that is characterized by the presence of abnormal white blood cells located_in peripheral blood, but in which the total number of white blood cells is normal.

What is bubonic plague?

A plague that results_in infection located_in lymph node producing a bubo, which is an inflamed, necrotic, and hemorrhagic lymphoid tissue. The infection has_symptom enlarged, tender lymph nodes, has_symptom fever, has_symptom chills and has_symptom prostration.

What is disseminated paracoccidioidomycosis?

A primary systemic mycosis that results_in systemic fungal infection through hematogenous spread, has_material_basis_in Paracoccidioides brasiliensis.

What is thoracic disease?

A disease of anatomical entity that is located_in the thoracic cavity.

What is complex genetic disease?

A genetic disease that require multiple abnormal alleles to manifest are complex. These diseases are termed multifactorial or polygenic. Expressivity or penetrance of the disease is complex and is associated with multiple genes in combination with lifestyle and environmental factors. Multifactoral genetic diseases include heart disease and diabetes, although a subset of diabetes may be classified as a monogenic disease (due to the presence of a single abnormal allele).

What is leukemia?

A cancer that affects the blood or bone marrow characterized by an abnormal proliferation of blood cells.

What is myeloid metaplasia?

A myeloma and spenic disease that is located_in the bone marrow that results_in the marrow being replaced by fibrous (scar) tissue and has_symptom abdominal fullness related to an enlarged spleen, has_symptom bone pain, has_symptom bruising, has_symptom easy bleeding, has_symptom fatigue, has_symptom increased susceptibility to infection, has_symptom pallor, has_symtom shortness of breath while doing physical work.

What is cervical dystonia?

A focal dystonia that is characterized by simultaneous contraction of the agonist and antagonist muscles that control the position of the head contracting during dystonic movement which causes the neck to involuntarily turn to the left, right, upwards, and/or downwards.

What is Townes-Brocks syndrome?

An autosomal dominant disease that is characterized by imperforate anus, dysplastic ears often associated with sensorineural and/or conductive hearing impairment, and thumb malformations.

What is pseudoachondroplasia?

An osteochondrodysplasia that has_material_basis_in mutations in the COMP gene which results_in short limb dwarfism.

What is bilirubin metabolic disorder?

An inherited metabolic disorder that involves elevated levels of bilirubin resulting from disruption of bilirubin metabolism.

What is mucopolysaccharidosis I?

A mucopolysaccharidosis characterized by a deficiency of the lysosomal enzyme alpha-L-iduronidase.

What is pulmonary paracoccidioidomycosis?

A primary systemic mycosis that results_in inflammation located_in lungs, has_material_basis_in Paracoccidioides brasiliensis and has_symptom cough, has_symptom fever, has_symptom night sweats, has_symptom malaise, and has_symptom weight loss.

What is papillary adenocarcinoma?

An adenocarcinoma that derives_from epithelial cells originating in glandular tissue, which form complex papillary structures and exhibit compressive, destructive growth that replaces the normal tissue.

What is fusariosis?

An opportunistic mycosis that involves localized or hematogenously disseminated fungal infection by Fusarium solani or Fusarium oxysporum. Skin lesions are seen in neutropenic patients, and indolent cellulitis or soft-tissue necrosis occur in immunocompromised patients at the site of trauma.